|
GB9206016D0
(en)
|
1992-03-19 |
1992-04-29 |
Sandoz Ltd |
Improvements in or relating to organic compounds
|
|
US5639872A
(en)
|
1993-07-27 |
1997-06-17 |
Hybridon, Inc. |
Human VEGF-specific oligonucleotides
|
|
US6440425B1
(en)
|
1995-05-01 |
2002-08-27 |
Aventis Pasteur Limited |
High molecular weight major outer membrane protein of moraxella
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
AU1686997A
(en)
|
1995-12-08 |
1997-06-27 |
Hybridon, Inc. |
Modified vegf antisense oligonucleotides for treatment of skin disorders
|
|
US6096548A
(en)
|
1996-03-25 |
2000-08-01 |
Maxygen, Inc. |
Method for directing evolution of a virus
|
|
EP0927044A4
(en)
|
1996-04-16 |
1999-09-08 |
Immusol Inc |
DEFINED TARGET VIRAL VECTORS
|
|
US6710036B2
(en)
|
1997-07-25 |
2004-03-23 |
Avigen, Inc. |
Induction of immune response to antigens expressed by recombinant adeno-associated virus
|
|
CA2303768C
(en)
|
1997-09-19 |
2009-11-24 |
The Trustees Of The University Of Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
EP1690868A1
(en)
|
1997-10-31 |
2006-08-16 |
Maxygen, Inc. |
Modification of virus tropism and host range by viral genome shuffling
|
|
US6410300B1
(en)
|
1998-01-12 |
2002-06-25 |
The University Of North Carolina At Chapel Hill |
Methods and formulations for mediating adeno-associated virus (AAV) attachment and infection and methods for purifying AAV
|
|
US6551795B1
(en)
|
1998-02-18 |
2003-04-22 |
Genome Therapeutics Corporation |
Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
|
|
DE19827457C1
(de)
|
1998-06-19 |
2000-03-02 |
Medigene Ag |
Strukturprotein von AAV, seine Herstellung und Verwendung
|
|
ATE294874T1
(de)
|
1998-09-11 |
2005-05-15 |
Univ California |
Rekombinante adenovirus für gewebespezifische genexpression ins herz
|
|
DE69941905D1
(de)
|
1998-11-10 |
2010-02-25 |
Univ North Carolina |
Virusvektoren und verfahren für ihre herstellung und verabreichung.
|
|
US6943153B1
(en)
|
1999-03-15 |
2005-09-13 |
The Regents Of The University Of California |
Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
US7314912B1
(en)
|
1999-06-21 |
2008-01-01 |
Medigene Aktiengesellschaft |
AAv scleroprotein, production and use thereof
|
|
DE19933288A1
(de)
|
1999-07-15 |
2001-01-18 |
Medigene Ag |
Strukturprotein von Adeno-assoziiertem Virus mit veränderter Antigenität, seine Herstellung und Verwendung
|
|
DE19933719A1
(de)
|
1999-07-19 |
2001-01-25 |
Medigene Ag |
Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung
|
|
US8232081B2
(en)
|
1999-09-21 |
2012-07-31 |
Basf Se |
Methods and microorganisms for production of panto-compounds
|
|
DE19961180C2
(de)
|
1999-12-18 |
2002-02-28 |
Daimler Chrysler Ag |
Dünnschichtwiderstand mit hohem Temperaturkoeffizienten als passives Halbleiterbauelement für integrierte Schaltungen und Herstellungsverfahren
|
|
WO2002081628A2
(en)
|
2001-04-05 |
2002-10-17 |
Ribozyme Pharmaceuticals, Incorporated |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies
|
|
US6855314B1
(en)
|
2000-03-22 |
2005-02-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
AAV5 vector for transducing brain cells and lung cells
|
|
US20030149235A1
(en)
|
2000-11-17 |
2003-08-07 |
Baker Andrew Howard |
Targeting peptides
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
US6962815B2
(en)
|
2001-01-05 |
2005-11-08 |
Children's Hopital Inc. |
AAV2 vectors and methods
|
|
US20030144221A1
(en)
|
2001-07-17 |
2003-07-31 |
Isis Pharmaceuticals Inc. |
Antisense modulation of BCL2-associated X protein expression
|
|
US7647184B2
(en)
|
2001-08-27 |
2010-01-12 |
Hanall Pharmaceuticals, Co. Ltd |
High throughput directed evolution by rational mutagenesis
|
|
US20030129203A1
(en)
|
2001-08-27 |
2003-07-10 |
Nautilus Biotech S.A. |
Mutant recombinant adeno-associated viruses
|
|
EP1572893B1
(en)
|
2001-11-09 |
2009-01-07 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Production of adeno-associated virus in insect cells
|
|
SG168422A1
(en)
|
2001-11-13 |
2011-02-28 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
US20050106558A1
(en)
|
2001-12-21 |
2005-05-19 |
Luca Perabo |
Library of modified structural genes or capsid modified particles useful for the identification of viral clones with desired cell tropism
|
|
US6846666B2
(en)
|
2002-03-21 |
2005-01-25 |
Council Of Scientific And Industrial Research |
Bacterial strain MTCC 5098 and a method of reducing total dissolved solids (TDS) from pulp and paper wastewater effluents using the said strain
|
|
WO2003089612A2
(en)
|
2002-04-17 |
2003-10-30 |
University Of Florida Research Foundation, Inc. |
IMPROVED rAAV VECTORS
|
|
WO2003093436A2
(en)
|
2002-04-30 |
2003-11-13 |
University Of Florida |
Treatment for phenylketonuria
|
|
AU2003223775A1
(en)
|
2002-04-30 |
2003-11-17 |
Duke University |
Adeno-associated viral vectors and methods for their production from hybrid adenovirus and for their use
|
|
US7071172B2
(en)
|
2002-04-30 |
2006-07-04 |
The University Of North Carolina At Chapel Hill |
Secretion signal vectors
|
|
US20060127358A1
(en)
|
2002-05-01 |
2006-06-15 |
Nicholas Muzyczka |
Raav expression systems and methods for enhancing transduction of mammalian neural cells
|
|
US7254489B2
(en)
|
2002-05-31 |
2007-08-07 |
Microsoft Corporation |
Systems, methods and apparatus for reconstructing phylogentic trees
|
|
US7148342B2
(en)
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
|
US7220577B2
(en)
|
2002-08-28 |
2007-05-22 |
University Of Florida Research Foundation, Inc. |
Modified AAV
|
|
US20070172460A1
(en)
|
2003-03-19 |
2007-07-26 |
Jurgen Kleinschmidt |
Random peptide library displayed on aav vectors
|
|
WO2004108922A2
(en)
|
2003-04-25 |
2004-12-16 |
The Trustees Of The University Of Pennsylvania |
Use of aav comprising a capsid protein from aav7 or aav8 for the delivery of genes encoding apoprotein a or e genes to the liver
|
|
EP1486567A1
(en)
|
2003-06-11 |
2004-12-15 |
Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts |
Improved adeno-associated virus (AAV) vector for gene therapy
|
|
PL2357189T3
(pl)
|
2003-06-19 |
2017-08-31 |
Genzyme Corporation |
Wiriony AAV o zmniejszonej immunoreaktywności i ich zastosowanie
|
|
JP2007524622A
(ja)
|
2003-06-23 |
2007-08-30 |
エイアンドジー ファーマスーティカルズ インコーポレイテッド |
抗癌治療に対する腫瘍細胞の感受性を回復させてアポトーシスを誘導するための組成物及び方法
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US20050019927A1
(en)
|
2003-07-13 |
2005-01-27 |
Markus Hildinger |
DECREASING GENE EXPRESSION IN A MAMMALIAN SUBJECT IN VIVO VIA AAV-MEDIATED RNAi EXPRESSION CASSETTE TRANSFER
|
|
WO2005047505A2
(en)
|
2003-08-07 |
2005-05-26 |
Whitehead Institute For Biomedical Research |
Methods and products for expression of micro rnas
|
|
US20050142581A1
(en)
|
2003-09-04 |
2005-06-30 |
Griffey Richard H. |
Microrna as ligands and target molecules
|
|
AU2004276316A1
(en)
|
2003-09-24 |
2005-04-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
IGF-1 instructs multipotent adult CNS neural stem cells to an oligodendroglial lineage
|
|
EP3910063A1
(en)
|
2003-09-30 |
2021-11-17 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
US20050266552A1
(en)
|
2003-12-05 |
2005-12-01 |
Doench John G |
Reagents and methods for identification of RNAi pathway genes and chemical modulators of RNAi
|
|
AU2005222902B2
(en)
|
2004-03-12 |
2010-06-10 |
Alnylam Pharmaceuticals, Inc. |
iRNA agents targeting VEGF
|
|
KR100614827B1
(ko)
|
2004-05-06 |
2006-08-25 |
재단법인서울대학교산학협력재단 |
양방향 은닉 마코프 모델을 이용한 완숙한마이크로알엔에이 위치예측방법 및 이를 구현하기 위한컴퓨터 프로그램을 기록한 저장매체
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
CN101124328A
(zh)
|
2004-12-15 |
2008-02-13 |
北卡罗来纳查佩尔山大学 |
嵌合载体
|
|
US20100172871A1
(en)
|
2005-02-17 |
2010-07-08 |
Flannery John G |
Muller Cell Specific Gene Therapy
|
|
EP3409296A1
(en)
|
2005-04-07 |
2018-12-05 |
The Trustees of the University of Pennsylvania |
Method of increasing the function of an aav vector
|
|
EP2465925A1
(en)
|
2005-07-22 |
2012-06-20 |
The Board Of Trustees Of The Leland |
Light-activated cation channel and uses thereof
|
|
WO2007089632A2
(en)
|
2006-01-27 |
2007-08-09 |
The University Of North Carolina At Chapel Hill |
Heparin and heparan sulfate binding chimeric vectors
|
|
EP2007795B1
(en)
|
2006-03-30 |
2016-11-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid proteins
|
|
CA2685900A1
(en)
|
2006-05-04 |
2007-11-15 |
Wayne State University |
Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids
|
|
US7872118B2
(en)
|
2006-09-08 |
2011-01-18 |
Opko Ophthalmics, Llc |
siRNA and methods of manufacture
|
|
CN1966082B
(zh)
|
2006-11-03 |
2010-06-30 |
许瑞安 |
一种防治结直肠癌的基因药物及其制备方法和用途
|
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
|
BRPI0810172A2
(pt)
|
2007-04-13 |
2014-10-14 |
Catalyst Biosciences Inc |
Polipeptídeos de fator vii modificado e seus usos
|
|
EP1985708B1
(en)
|
2007-04-27 |
2015-04-15 |
Universität Rostock |
Selective targeting of viruses to neural precursor cells
|
|
US8632764B2
(en)
|
2008-04-30 |
2014-01-21 |
University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
|
EP2910637A1
(en)
|
2008-05-20 |
2015-08-26 |
University of Florida Research Foundation, Inc. |
Vectors for delivery of light-sensitive proteins and methods of use
|
|
US20110171262A1
(en)
|
2008-06-17 |
2011-07-14 |
Andrew Christian Bakker |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
WO2010093784A2
(en)
|
2009-02-11 |
2010-08-19 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
CN101532024A
(zh)
|
2009-04-30 |
2009-09-16 |
许瑞安 |
一种用于基因治疗的新型细胞特异性内含microRNA结合序列的基因HAAVmir
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
CN106011073A
(zh)
|
2010-03-17 |
2016-10-12 |
小利兰·斯坦福大学托管委员会 |
光敏离子透过性分子
|
|
WO2011117258A2
(en)
|
2010-03-22 |
2011-09-29 |
Association Institut De Myologie |
Methods of increasing efficiency of vector penetration of target tissue
|
|
US8263396B2
(en)
|
2010-04-01 |
2012-09-11 |
Weidong Xiao |
Methods and compositions for the production of recombinant virus vectors
|
|
CN103025344B
(zh)
|
2010-05-17 |
2016-06-29 |
桑格摩生物科学股份有限公司 |
新型dna-结合蛋白及其用途
|
|
US8663624B2
(en)
|
2010-10-06 |
2014-03-04 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
|
EP2634253B1
(en)
|
2010-10-27 |
2016-05-11 |
Jichi Medical University |
Adeno-associated virus virions for transferring genes into neural cells
|
|
CA2816990A1
(en)
|
2010-11-05 |
2012-05-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Stabilized step function opsin proteins and methods of using the same
|
|
EP3486253A1
(en)
|
2010-11-05 |
2019-05-22 |
The Board of Trustees of The Leland Stanford Junior University |
Light-activated chimeric opsins and methods of using the same
|
|
LT3254703T
(lt)
|
2011-04-22 |
2020-05-25 |
The Regents Of The University Of California |
Adenoasocijuoto viruso virionai su variantine kapside ir jų panaudojimo būdai
|
|
EP2748185A1
(en)
|
2011-08-24 |
2014-07-02 |
The Board of Trustees of The Leland Stanford Junior University |
New aav capsid proteins for nucleic acid transfer
|
|
CA2870736C
(en)
|
2012-04-18 |
2021-11-02 |
The Children's Hospital Of Philadelphia |
Composition and methods for highly efficient gene transfer using aav capsid variants
|
|
JP6385920B2
(ja)
|
2012-05-09 |
2018-09-05 |
オレゴン ヘルス アンド サイエンス ユニバーシティー |
アデノ随伴ウイルスプラスミド及びベクター
|
|
TWI775096B
(zh)
|
2012-05-15 |
2022-08-21 |
澳大利亞商艾佛蘭屈澳洲私營有限公司 |
使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
|
|
JP6363958B2
(ja)
*
|
2012-12-25 |
2018-07-25 |
タカラバイオ株式会社 |
Aav変異体
|
|
DK2954051T3
(da)
*
|
2013-02-08 |
2019-07-08 |
Univ Pennsylvania |
Modificeret kapsid til genoverførsel til behandling af nethinden
|
|
JP6670743B2
(ja)
|
2013-05-29 |
2020-03-25 |
セレクティスCellectis |
Ii型crisprシステムにおける新規のコンパクトなcas9足場
|
|
WO2014194132A1
(en)
|
2013-05-31 |
2014-12-04 |
The Regents Of The University Of California |
Adeno-associated virus variants and methods of use thereof
|
|
WO2014200910A2
(en)
|
2013-06-10 |
2014-12-18 |
Iogenetics, Llc |
Bioinformatic processes for determination of peptide binding
|
|
ES2716615T3
(es)
|
2013-06-28 |
2019-06-13 |
Inst Nat Sante Rech Med |
Métodos para expresar un polinucleótido de interés en la retina de un sujeto
|
|
WO2015012501A1
(ko)
|
2013-07-25 |
2015-01-29 |
주식회사 스마트캐스터 |
비공기압 바퀴
|
|
EP3633041A3
(en)
|
2013-09-26 |
2020-07-29 |
University of Florida Research Foundation, Inc. |
Synthetic combinatorial aav capsid library for targeted gene therapy
|
|
NZ758025A
(en)
|
2013-10-11 |
2022-07-01 |
Massachusetts Eye & Ear Infirmary |
Methods of predicting ancestral virus sequences and uses thereof
|
|
WO2015089486A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
|
GB201403684D0
(en)
*
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
CA2942776C
(en)
|
2014-03-17 |
2023-01-24 |
Adverum Biotechnologies, Inc. |
Polyneucleotide cassette and expression vector for expression of a gene in cone cells using truncated m-opsin promoter
|
|
LT3137497T
(lt)
*
|
2014-05-02 |
2021-07-26 |
Genzyme Corporation |
Aav vektoriai, skirti tinklainės ir cns genų terapijai
|
|
CA2951707A1
(en)
|
2014-06-10 |
2015-12-17 |
Massachusetts Institute Of Technology |
Method for gene editing
|
|
DE102014217790A1
(de)
|
2014-09-05 |
2016-03-10 |
Evonik Degussa Gmbh |
Verfahren zur Herstellung von hydrosilylierbaren Eugenol-Polyethern und Eugenol-Polyethersiloxanen sowie deren Verwendung
|
|
ES2920850T3
(es)
*
|
2015-02-20 |
2022-08-10 |
Univ Iowa Res Found |
Procedimientos y composiciones para el tratamiento de enfermedades oculares genéticas
|
|
KR20170137730A
(ko)
|
2015-03-02 |
2017-12-13 |
애드베룸 바이오테크놀로지스, 인코포레이티드 |
망막 추상체에 폴리뉴클레오타이드의 유리체 내 전달을 위한 조성물 및 방법
|
|
HRP20201225T1
(hr)
|
2015-03-06 |
2020-11-13 |
Massachusetts Eye & Ear Infirmary |
Terapije poboljšavanja gena kod nasljedne degeneracije mrežnice uzrokovanu mutacijama u genu prpf31
|
|
WO2016154344A1
(en)
|
2015-03-24 |
2016-09-29 |
The Regents Of The University Of California |
Adeno-associated virus variants and methods of use thereof
|
|
WO2017023724A1
(en)
|
2015-07-31 |
2017-02-09 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
MX2018013463A
(es)
|
2016-05-13 |
2019-07-04 |
4D Molecular Therapeutics Inc |
Capsides variantes de virus adenoasociados y metodos de uso de las mismas.
|
|
MA44546B1
(fr)
|
2016-06-15 |
2021-03-31 |
Univ California |
Virus adéno-associés variants et procédés d'utilisation
|
|
KR20230039779A
(ko)
|
2016-07-29 |
2023-03-21 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
변이체 캡시드를 갖는 아데노-관련된 바이러스 비리온 및 이의 사용 방법
|
|
EP3676373A4
(en)
*
|
2017-08-28 |
2021-06-09 |
The Regents of The University of California |
Adeno-associated virus capsid variants and methods of use thereof
|