JP2023513004A5 - - Google Patents
Info
- Publication number
- JP2023513004A5 JP2023513004A5 JP2022545976A JP2022545976A JP2023513004A5 JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5 JP 2022545976 A JP2022545976 A JP 2022545976A JP 2022545976 A JP2022545976 A JP 2022545976A JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- sequence
- capsid protein
- raav
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062967416P | 2020-01-29 | 2020-01-29 | |
| US62/967,416 | 2020-01-29 | ||
| PCT/US2021/015695 WO2021155137A1 (en) | 2020-01-29 | 2021-01-29 | Modified adeno-associated viral capsid proteins for ocular gene therapy and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026082295A Division JP2026133539A (ja) | 2020-01-29 | 2026-05-15 | 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513004A JP2023513004A (ja) | 2023-03-30 |
| JP2023513004A5 true JP2023513004A5 (enExample) | 2024-02-02 |
| JP7866941B2 JP7866941B2 (ja) | 2026-05-28 |
Family
ID=74673421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545976A Active JP7866941B2 (ja) | 2020-01-29 | 2021-01-29 | 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210261625A1 (enExample) |
| EP (1) | EP4097121A1 (enExample) |
| JP (1) | JP7866941B2 (enExample) |
| KR (1) | KR20220133941A (enExample) |
| CN (1) | CN115989234A (enExample) |
| AR (1) | AR121228A1 (enExample) |
| AU (2) | AU2021213786A1 (enExample) |
| BR (1) | BR112022014852A2 (enExample) |
| CA (1) | CA3165019A1 (enExample) |
| CO (1) | CO2022010227A2 (enExample) |
| IL (1) | IL294868A (enExample) |
| MX (1) | MX2022009252A (enExample) |
| PH (1) | PH12022551878A1 (enExample) |
| WO (1) | WO2021155137A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| US20260000790A1 (en) | 2022-07-08 | 2026-01-01 | Ospedale San Raffaele S.R.L. | Transgene cassettes |
| EP4303226A1 (en) | 2022-07-08 | 2024-01-10 | Ospedale San Raffaele S.r.l. | Transgene cassettes and epigenetic silencers for the treatment of disorders |
| KR102901502B1 (ko) | 2024-06-27 | 2025-12-18 | 이엔셀 주식회사 | 안구 세포 또는 조직을 표적하는 펩타이드 및 이를 포함하는 바이러스 캡시드 단백질 및 바이러스 벡터 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2264482A1 (en) | 1996-09-06 | 1998-03-12 | The Trustees Of The University Of Pennsylvania | An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase |
| NZ500427A (en) | 1997-04-21 | 2002-12-20 | Univ Florida | The use of ribozyme treatment for retinal diseases |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6995006B2 (en) | 1997-09-05 | 2006-02-07 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| JP4559429B2 (ja) | 2003-05-21 | 2010-10-06 | ジェンザイム・コーポレーション | 空キャプシドを実質的に含まない組換えａａｖビリオン調製物を生成するための方法 |
| DK2623605T3 (en) | 2007-04-09 | 2019-03-25 | Univ Florida | RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF |
| US20100081707A1 (en) | 2008-02-21 | 2010-04-01 | Ali Robin R | Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea |
| JP5956331B2 (ja) | 2009-06-16 | 2016-07-27 | ジェンザイム・コーポレーション | 組換えａａｖベクターの改良された精製方法 |
| DK2561073T3 (en) | 2010-04-23 | 2016-12-12 | Univ Massachusetts | Aav vectors targeted to central nervous system and methods of use thereof |
| CA2826273C (en) * | 2011-02-10 | 2021-11-02 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| PT3628334T (pt) * | 2014-03-21 | 2023-09-26 | Genzyme Corp | Terapia genética para retinopatia pigmentar |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| WO2016065001A1 (en) * | 2014-10-21 | 2016-04-28 | University Of Massachusetts | Recombinant aav variants and uses thereof |
| HUE053747T2 (hu) | 2016-08-15 | 2021-07-28 | Genzyme Corp | Eljárások AAV kimutatására |
| CA3033125A1 (en) * | 2016-08-16 | 2018-02-22 | The University Of North Carolina At Chapel Hill | Methods and compositions for targeted gene transfer |
| WO2019221992A1 (en) * | 2018-05-15 | 2019-11-21 | President And Fellows Of Harvard College | Viral vectors exhibiting improved gene delivery properties |
-
2021
- 2021-01-29 WO PCT/US2021/015695 patent/WO2021155137A1/en not_active Ceased
- 2021-01-29 KR KR1020227029428A patent/KR20220133941A/ko active Pending
- 2021-01-29 CN CN202180011349.3A patent/CN115989234A/zh active Pending
- 2021-01-29 AU AU2021213786A patent/AU2021213786A1/en active Pending
- 2021-01-29 MX MX2022009252A patent/MX2022009252A/es unknown
- 2021-01-29 IL IL294868A patent/IL294868A/en unknown
- 2021-01-29 EP EP21707556.3A patent/EP4097121A1/en active Pending
- 2021-01-29 JP JP2022545976A patent/JP7866941B2/ja active Active
- 2021-01-29 CA CA3165019A patent/CA3165019A1/en active Pending
- 2021-01-29 US US17/162,356 patent/US20210261625A1/en active Pending
- 2021-01-29 PH PH1/2022/551878A patent/PH12022551878A1/en unknown
- 2021-01-29 AR ARP210100248A patent/AR121228A1/es unknown
- 2021-01-29 BR BR112022014852A patent/BR112022014852A2/pt unknown
-
2022
- 2022-07-19 CO CONC2022/0010227A patent/CO2022010227A2/es unknown
-
2026
- 2026-04-29 AU AU2026203237A patent/AU2026203237A1/en active Pending
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