JP2023513004A5 - - Google Patents
Info
- Publication number
- JP2023513004A5 JP2023513004A5 JP2022545976A JP2022545976A JP2023513004A5 JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5 JP 2022545976 A JP2022545976 A JP 2022545976A JP 2022545976 A JP2022545976 A JP 2022545976A JP 2023513004 A5 JP2023513004 A5 JP 2023513004A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- sequence
- capsid protein
- raav
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062967416P | 2020-01-29 | 2020-01-29 | |
| US62/967,416 | 2020-01-29 | ||
| PCT/US2021/015695 WO2021155137A1 (en) | 2020-01-29 | 2021-01-29 | Modified adeno-associated viral capsid proteins for ocular gene therapy and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023513004A JP2023513004A (ja) | 2023-03-30 |
| JP2023513004A5 true JP2023513004A5 (enExample) | 2024-02-02 |
Family
ID=74673421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545976A Pending JP2023513004A (ja) | 2020-01-29 | 2021-01-29 | 眼科遺伝子療法のための改変されたアデノ随伴ウイルスカプシドタンパク質およびその使用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20210261625A1 (enExample) |
| EP (1) | EP4097121A1 (enExample) |
| JP (1) | JP2023513004A (enExample) |
| KR (1) | KR20220133941A (enExample) |
| CN (1) | CN115989234A (enExample) |
| AR (1) | AR121228A1 (enExample) |
| AU (1) | AU2021213786A1 (enExample) |
| BR (1) | BR112022014852A2 (enExample) |
| CA (1) | CA3165019A1 (enExample) |
| CO (1) | CO2022010227A2 (enExample) |
| IL (1) | IL294868A (enExample) |
| MX (1) | MX2022009252A (enExample) |
| PH (1) | PH12022551878A1 (enExample) |
| TW (1) | TW202142552A (enExample) |
| WO (1) | WO2021155137A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| EP4551253A1 (en) | 2022-07-08 | 2025-05-14 | Ospedale San Raffaele S.r.l. | Transgene cassettes |
| EP4303226A1 (en) | 2022-07-08 | 2024-01-10 | Ospedale San Raffaele S.r.l. | Transgene cassettes and epigenetic silencers for the treatment of disorders |
| KR102901502B1 (ko) | 2024-06-27 | 2025-12-18 | 이엔셀 주식회사 | 안구 세포 또는 조직을 표적하는 펩타이드 및 이를 포함하는 바이러스 캡시드 단백질 및 바이러스 벡터 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0931158A1 (en) | 1996-09-06 | 1999-07-28 | The Trustees Of The University Of Pennsylvania | An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase |
| WO1998048009A2 (en) | 1997-04-21 | 1998-10-29 | University Of Florida | Materials and methods for ribozyme treatment of retinal diseases |
| US6989264B2 (en) | 1997-09-05 | 2006-01-24 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| US7261544B2 (en) | 2003-05-21 | 2007-08-28 | Genzyme Corporation | Methods for producing preparations of recombinant AAV virions substantially free of empty capsids |
| ES2714007T3 (es) | 2007-04-09 | 2019-05-24 | Univ Florida | Composiciones de vectores rAAV que tienen proteínas de la cápside modificadas en tirosina y métodos para su uso |
| US20100081707A1 (en) | 2008-02-21 | 2010-04-01 | Ali Robin R | Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea |
| KR20180000341A (ko) | 2009-06-16 | 2018-01-02 | 젠자임 코포레이션 | 재조합 ａａｖ 벡터에 대한 개선된 정제 방법 |
| EP2561073B1 (en) | 2010-04-23 | 2016-08-24 | University of Massachusetts | Cns targeting aav vectors and methods of use thereof |
| WO2012109570A1 (en) * | 2011-02-10 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| PL3628334T3 (pl) * | 2014-03-21 | 2023-12-18 | Genzyme Corporation | Terapia genowa w retinopatii barwnikowej |
| LT3137497T (lt) | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| CN107073051B (zh) * | 2014-10-21 | 2021-08-24 | 马萨诸塞大学 | 重组aav变体及其用途 |
| CA3033856A1 (en) | 2016-08-15 | 2018-02-22 | Genzyme Corporation | Methods for detecting aav |
| US20190262373A1 (en) * | 2016-08-16 | 2019-08-29 | The University Of North Carolina At Chapel Hill | Methods and compositions for targeted gene transfer |
| EP3813845A4 (en) * | 2018-05-15 | 2022-10-26 | President And Fellows Of Harvard College | Viral vectors exhibiting improved gene delivery properties |
-
2021
- 2021-01-29 EP EP21707556.3A patent/EP4097121A1/en active Pending
- 2021-01-29 CN CN202180011349.3A patent/CN115989234A/zh active Pending
- 2021-01-29 TW TW110103551A patent/TW202142552A/zh unknown
- 2021-01-29 CA CA3165019A patent/CA3165019A1/en active Pending
- 2021-01-29 KR KR1020227029428A patent/KR20220133941A/ko active Pending
- 2021-01-29 AU AU2021213786A patent/AU2021213786A1/en active Pending
- 2021-01-29 AR ARP210100248A patent/AR121228A1/es unknown
- 2021-01-29 JP JP2022545976A patent/JP2023513004A/ja active Pending
- 2021-01-29 US US17/162,356 patent/US20210261625A1/en active Pending
- 2021-01-29 IL IL294868A patent/IL294868A/en unknown
- 2021-01-29 PH PH1/2022/551878A patent/PH12022551878A1/en unknown
- 2021-01-29 WO PCT/US2021/015695 patent/WO2021155137A1/en not_active Ceased
- 2021-01-29 MX MX2022009252A patent/MX2022009252A/es unknown
- 2021-01-29 BR BR112022014852A patent/BR112022014852A2/pt unknown
-
2022
- 2022-07-19 CO CONC2022/0010227A patent/CO2022010227A2/es unknown
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