JP2022552892A5 - - Google Patents
Info
- Publication number
- JP2022552892A5 JP2022552892A5 JP2022523659A JP2022523659A JP2022552892A5 JP 2022552892 A5 JP2022552892 A5 JP 2022552892A5 JP 2022523659 A JP2022523659 A JP 2022523659A JP 2022523659 A JP2022523659 A JP 2022523659A JP 2022552892 A5 JP2022552892 A5 JP 2022552892A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- nucleic acid
- aav3b
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962924112P | 2019-10-21 | 2019-10-21 | |
| US62/924,112 | 2019-10-21 | ||
| US202063025753P | 2020-05-15 | 2020-05-15 | |
| US63/025,753 | 2020-05-15 | ||
| PCT/US2020/056511 WO2021080991A1 (en) | 2019-10-21 | 2020-10-20 | Aav3b variants with improved production yield and liver tropism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022552892A JP2022552892A (ja) | 2022-12-20 |
| JP2022552892A5 true JP2022552892A5 (enExample) | 2023-10-18 |
Family
ID=75620806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022523659A Pending JP2022552892A (ja) | 2019-10-21 | 2020-10-20 | 改善された産生収率および肝臓向性を有するａａｖ３ｂ変異体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20230002788A1 (enExample) |
| EP (1) | EP4048681A4 (enExample) |
| JP (1) | JP2022552892A (enExample) |
| AU (1) | AU2020369508A1 (enExample) |
| CA (1) | CA3155016A1 (enExample) |
| TW (1) | TW202130653A (enExample) |
| WO (1) | WO2021080991A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113444785B (zh) * | 2021-06-28 | 2022-06-21 | 甘肃农业大学 | 一种与仔猪C型产气荚膜梭菌感染性腹泻相关的ssc-miR-122-5p及其应用 |
| WO2023049846A1 (en) * | 2021-09-24 | 2023-03-30 | The Trustees Of The University Of Pennsylvania | Compositions useful for treatment of charcot-marie-tooth disease |
| WO2023196892A1 (en) | 2022-04-06 | 2023-10-12 | The Trustees Of The University Of Pennsylvania | Passive immunization with anti- aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6156303A (en) * | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| US7749492B2 (en) * | 2001-01-05 | 2010-07-06 | Nationwide Children's Hospital, Inc. | AAV vectors and methods |
| CN107073051B (zh) * | 2014-10-21 | 2021-08-24 | 马萨诸塞大学 | 重组aav变体及其用途 |
| US10081659B2 (en) * | 2015-04-06 | 2018-09-25 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Adeno-associated vectors for enhanced transduction and reduced immunogenicity |
| US11364308B2 (en) * | 2016-05-13 | 2022-06-21 | 4D Molecular Therapeutics Inc. | Adeno-associated virus variant capsids and methods of use thereof |
| EP3585900B1 (en) * | 2017-02-22 | 2022-12-21 | CRISPR Therapeutics AG | Materials and methods for treatment of spinocerebellar ataxia type 2 (sca2) and other spinocerebellar ataxia type 2 protein (atxn2) gene related conditions or disorders |
| WO2018200419A1 (en) * | 2017-04-23 | 2018-11-01 | The Trustees Of The University Of Pennsylvania | Viral vectors comprising engineered aav capsids and compositions containing the same |
| EP3768695A4 (en) * | 2018-02-27 | 2022-04-06 | The Trustees of the University of Pennsylvania | NOVEL ADENO-ASSOCIATED VIRUS (AAV) VECTORS, AAV VECTORS WITH REDUCED CAPSIID DEAMIDATION AND USES THEREOF |
| IL276859B2 (en) * | 2018-02-27 | 2025-12-01 | Univ Pennsylvania | Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor |
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2020
- 2020-10-20 EP EP20878199.7A patent/EP4048681A4/en not_active Withdrawn
- 2020-10-20 JP JP2022523659A patent/JP2022552892A/ja active Pending
- 2020-10-20 US US17/770,138 patent/US20230002788A1/en not_active Abandoned
- 2020-10-20 WO PCT/US2020/056511 patent/WO2021080991A1/en not_active Ceased
- 2020-10-20 TW TW109136242A patent/TW202130653A/zh unknown
- 2020-10-20 AU AU2020369508A patent/AU2020369508A1/en not_active Abandoned
- 2020-10-20 CA CA3155016A patent/CA3155016A1/en active Pending