|
SG10202108118RA
(en)
|
2001-11-13 |
2021-08-30 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
HUE054805T2
(hu)
|
2003-09-30 |
2021-09-28 |
Univ Pennsylvania |
Adeno-asszociált vírus (AAV) kládok, szekvenciák, az azokat tartalmazó vektorok és alkalmazásaik
|
|
US9198984B2
(en)
|
2006-04-28 |
2015-12-01 |
The Trustees Of The University Of Pennsylvania |
Scalable production method for AAV
|
|
CN101511373B
(zh)
*
|
2006-06-19 |
2015-12-09 |
阿斯克肋匹奥生物制药公司 |
用于基因治疗的修饰的因子ⅷ和因子ⅸ基因和载体
|
|
HUE030719T2
(en)
|
2007-04-09 |
2017-05-29 |
Univ Florida |
Raav vector compositions having tyrosine-modified capsid proteins and methods for use
|
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
|
EP2315833B8
(en)
|
2008-05-20 |
2015-05-27 |
Eos Neuroscience, Inc. |
Vectors for delivery of light-sensitive proteins and methods of use
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
US11219696B2
(en)
|
2008-12-19 |
2022-01-11 |
Nationwide Children's Hospital |
Delivery of polynucleotides using recombinant AAV9
|
|
ES2724122T3
(es)
*
|
2009-04-30 |
2019-09-06 |
Univ Pennsylvania |
Composiciones para dirigir células de las vías respiratorias de conducción que comprenden construcciones de virus adenoasociado
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
WO2011038187A1
(en)
|
2009-09-25 |
2011-03-31 |
The Trustees Of The University Of Pennsylvania |
Controlled adeno-associated virus (aav) diversification and libraries prepared therefrom
|
|
KR20130040844A
(ko)
|
2010-03-29 |
2013-04-24 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
약학적으로 유발된 전이유전자 제거 시스템
|
|
US9315825B2
(en)
|
2010-03-29 |
2016-04-19 |
The Trustees Of The University Of Pennsylvania |
Pharmacologically induced transgene ablation system
|
|
EP3567106A1
(en)
|
2010-04-23 |
2019-11-13 |
University of Massachusetts |
Cns targeting aav vectors and methods of use thereof
|
|
US9272053B2
(en)
|
2010-04-23 |
2016-03-01 |
University Of Massachusetts |
AAV-based treatment of cholesterol-related disorders
|
|
CA2833905C
(en)
|
2010-04-23 |
2019-09-10 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
US9309534B2
(en)
|
2010-07-12 |
2016-04-12 |
Universidad Autonoma De Barcelona |
Gene therapy composition for use in diabetes treatment
|
|
US8663624B2
(en)
|
2010-10-06 |
2014-03-04 |
The Regents Of The University Of California |
Adeno-associated virus virions with variant capsid and methods of use thereof
|
|
CN107828820B
(zh)
*
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
EP2699688A1
(en)
|
2011-04-20 |
2014-02-26 |
The Trustees Of The University Of Pennsylvania |
Regimens and compositions for aav-mediated passive immunization of airborne pathogens
|
|
US9226976B2
(en)
|
2011-04-21 |
2016-01-05 |
University Of Massachusetts |
RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
CN107012171B
(zh)
|
2011-04-22 |
2021-07-13 |
加利福尼亚大学董事会 |
具有变异衣壳的腺相关病毒病毒体及其使用方法
|
|
US20130039888A1
(en)
|
2011-06-08 |
2013-02-14 |
Nationwide Children's Hospital Inc. |
Products and methods for delivery of polynucleotides by adeno-associated virus for lysosomal storage disorders
|
|
KR102057540B1
(ko)
*
|
2012-02-17 |
2019-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
세포, 기관 및 조직으로의 유전자 전이를 위한 aav 벡터 조성물 및 방법
|
|
JP6342886B2
(ja)
|
2012-04-18 |
2018-06-13 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia |
Aavカプシドバリアントを使用した高効率な遺伝子導入のための組成物及び方法
|
|
TWI775096B
(zh)
|
2012-05-15 |
2022-08-21 |
澳大利亞商艾佛蘭屈澳洲私營有限公司 |
使用腺相關病毒(aav)sflt-1治療老年性黃斑部退化(amd)
|
|
US10294281B2
(en)
|
2012-05-15 |
2019-05-21 |
University Of Florida Research Foundation, Incorporated |
High-transduction-efficiency rAAV vectors, compositions, and methods of use
|
|
US12358954B2
(en)
|
2012-05-15 |
2025-07-15 |
University Of Florida Research Foundation, Incorporated |
Capsid-modified rAAV vector compositions and methods therefor
|
|
BR112015002168A2
(pt)
|
2012-08-01 |
2017-11-07 |
Nationwide Childrens Hospital |
liberação intratecal de vírus 9 adeno-associado recombinante
|
|
EP2692868A1
(en)
|
2012-08-02 |
2014-02-05 |
Universitat Autònoma De Barcelona |
Adeno-associated viral (AAV) vectors useful for transducing adipose tissue
|
|
PL2900686T3
(pl)
|
2012-09-28 |
2021-01-25 |
The University Of North Carolina At Chapel Hill |
Wektory aav ukierunkowane na oligodendrocyty
|
|
JP6591956B2
(ja)
|
2013-03-15 |
2019-10-16 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
Mps1を治療するための組成物および方法
|
|
WO2015012924A2
(en)
|
2013-04-29 |
2015-01-29 |
The Trustees Of The University Of Pennsylvania |
Tissue preferential codon modified expression cassettes, vectors containing same, and use thereof
|
|
KR102298579B1
(ko)
*
|
2013-05-21 |
2021-09-07 |
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 |
캡시드-변형된 raav3 벡터 조성물, 및 인간 간암의 유전자 요법에서의 용도
|
|
CN105247044B
(zh)
*
|
2013-05-31 |
2021-05-07 |
加利福尼亚大学董事会 |
腺相关病毒变体及其使用方法
|
|
PT3024498T
(pt)
*
|
2013-07-22 |
2020-03-06 |
Childrens Hospital Philadelphia |
Variante aav e composições, métodos e usos para transferência genética em células, órgãos e tecidos
|
|
AU2014324717B2
(en)
|
2013-09-26 |
2020-10-08 |
University Of Florida Research Foundation, Inc. |
Synthetic combinatorial AAV capsid library for targeted gene therapy
|
|
US20150098925A1
(en)
*
|
2013-10-07 |
2015-04-09 |
Kiromic, Llc |
Compositions and methods for treating cardiovascular diseases using disease-specific promoter
|
|
NZ718926A
(en)
|
2013-10-11 |
2021-12-24 |
Massachusetts Eye & Ear Infirmary |
Methods of predicting ancestral virus sequences and uses thereof
|
|
GB201403684D0
(en)
*
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
US10072251B2
(en)
|
2014-02-19 |
2018-09-11 |
University Of Massachusetts |
Recombinant AAVS having useful transcytosis properties
|
|
JP6822841B2
(ja)
|
2014-03-09 |
2021-01-27 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
オルニチントランスカルバミラーゼ(otc)欠損症の処置において有用な組成物
|
|
EP3800191B1
(en)
|
2014-03-17 |
2025-08-20 |
Adverum Biotechnologies, Inc. |
Compositions and methods for enhanced gene expression in cone cells
|
|
CA3276269A1
(en)
|
2014-03-18 |
2026-03-02 |
University Of Massachusetts |
Raav-based compositions and methods for treating amyotrophic lateral sclerosis
|
|
CA2946392A1
(en)
|
2014-04-25 |
2015-10-29 |
James M. Wilson |
Ldlr variants and their use in compositions for reducing cholesterol levels
|
|
WO2015164723A1
(en)
|
2014-04-25 |
2015-10-29 |
The Trustees Of The University Of Pennsylvania |
Methods and compositions for treating metastatic breast cancer and other cancers in the brain
|
|
EP3137497B2
(en)
|
2014-05-02 |
2025-03-05 |
Genzyme Corporation |
Aav vectors for retinal and cns gene therapy
|
|
MY186389A
(en)
|
2014-05-13 |
2021-07-22 |
Univ Pennsylvania |
Compositions comprising aav expressing dual antibody constructs and uses thereof
|
|
US10577627B2
(en)
|
2014-06-09 |
2020-03-03 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
CN107427557B
(zh)
*
|
2014-08-13 |
2022-01-04 |
费城儿童医院 |
用于包装和表达变体因子viii以治疗血友病的改良表达组件
|
|
WO2016041588A1
(en)
|
2014-09-16 |
2016-03-24 |
Universitat Autònoma De Barcelona |
Adeno-associated viral vectors for the gene therapy of metabolic diseases
|
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
|
EP3200830B1
(en)
|
2014-10-03 |
2020-09-09 |
University of Massachusetts |
High efficiency library-identified aav vectors
|
|
RU2020140209A
(ru)
|
2014-10-21 |
2021-01-25 |
Юниверсити Оф Массачусетс |
Варианты рекомбинантных aav и их применения
|
|
CN107106689A
(zh)
|
2014-11-05 |
2017-08-29 |
沃雅戈治疗公司 |
用于治疗帕金森病的aadc多核苷酸
|
|
GB201420139D0
(en)
|
2014-11-12 |
2014-12-24 |
Ucl Business Plc |
Factor IX gene therapy
|
|
CN112410338A
(zh)
|
2014-11-14 |
2021-02-26 |
沃雅戈治疗公司 |
调节性多核苷酸
|
|
IL292999A
(en)
|
2014-11-14 |
2022-07-01 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
EP4344741A3
(en)
|
2014-11-21 |
2024-08-28 |
The University of North Carolina at Chapel Hill |
Aav vectors targeted to the central nervous system
|
|
WO2016094783A1
(en)
|
2014-12-12 |
2016-06-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the production of scaav
|
|
US10876134B2
(en)
|
2014-12-16 |
2020-12-29 |
Board Of Regents Of The University Of Nebraska |
Gene therapy for juvenile batten disease
|
|
EP3242945B1
(en)
|
2015-01-07 |
2021-09-01 |
Universitat Autònoma de Barcelona |
Single-vector gene construct comprising insulin and glucokinase genes
|
|
US20180030096A1
(en)
|
2015-02-03 |
2018-02-01 |
University Of Florida Research Foundation, Inc. |
Recombinant aav1, aav5, and aav6 capsid mutants and uses thereof
|
|
JP6929791B2
(ja)
|
2015-02-09 |
2021-09-01 |
デューク ユニバーシティ |
エピゲノム編集のための組成物および方法
|
|
WO2016131009A1
(en)
|
2015-02-13 |
2016-08-18 |
University Of Massachusetts |
Compositions and methods for transient delivery of nucleases
|
|
JP7095994B2
(ja)
|
2015-03-02 |
2022-07-05 |
アドヴェラム バイオテクノロジーズ, インコーポレイテッド |
ポリヌクレオチドを網膜錐体に硝子体内送達するための組成物及び方法
|
|
ES2836258T3
(es)
|
2015-03-10 |
2021-06-24 |
Univ Columbia |
Construcciones de vectores virales adenoasociados de GLUT1 recombinante y métodos relacionados para restaurar la expresión de GLUT1
|
|
ES2860712T3
(es)
|
2015-03-24 |
2021-10-05 |
Univ California |
Variantes de virus adenoasociados y métodos de uso de las mismas
|
|
CN107531760A
(zh)
*
|
2015-03-30 |
2018-01-02 |
勃林格殷格翰动物保健公司 |
Pcv2 orf2载体平台
|
|
JP6851319B2
(ja)
|
2015-04-27 |
2021-03-31 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ヒト疾患のCRISPR/Cas9媒介性の修正のためのデュアルAAVベクター系
|
|
AU2016256894B2
(en)
|
2015-05-07 |
2020-11-26 |
Massachusetts Eye And Ear Infirmary |
Methods of delivering an agent to the eye
|
|
EA201792500A1
(ru)
|
2015-05-13 |
2018-04-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Aav-опосредованная экспрессия антител против гриппа и способы их использования
|
|
PT3313991T
(pt)
|
2015-06-23 |
2024-09-27 |
Childrens Hospital Philadelphia |
Fator ix modificado e composições, métodos e utilizações para transferência de genes para células, órgãos e tecidos
|
|
WO2017015637A1
(en)
|
2015-07-22 |
2017-01-26 |
Duke University |
High-throughput screening of regulatory element function with epigenome editing technologies
|
|
EP4134375A1
(en)
*
|
2015-07-30 |
2023-02-15 |
Massachusetts Eye & Ear Infirmary |
Ancestral adeno associated virus sequences and uses thereof
|
|
GB2557123B
(en)
|
2015-07-31 |
2021-11-03 |
Univ Minnesota |
Modified cells and methods of therapy
|
|
US12221615B2
(en)
|
2015-08-06 |
2025-02-11 |
The Trustees Of The University Of Pennsylvania |
GLP-1 and use thereof in compositions for treating metabolic diseases
|
|
WO2017035416A2
(en)
|
2015-08-25 |
2017-03-02 |
Duke University |
Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases
|
|
CA2995733A1
(en)
*
|
2015-08-31 |
2017-03-09 |
The Trustees Of The University Of Pennsylvania |
Aav-epo for treating companion animals
|
|
EP3359663A4
(en)
|
2015-09-24 |
2019-08-14 |
The Trustees of The University of Pennsylvania |
COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE
|
|
WO2017062750A1
(en)
|
2015-10-09 |
2017-04-13 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods useful in treating stargardt's disease and other ocular disorders
|
|
EP4089175A1
(en)
|
2015-10-13 |
2022-11-16 |
Duke University |
Genome engineering with type i crispr systems in eukaryotic cells
|
|
US12188037B2
(en)
*
|
2015-10-22 |
2025-01-07 |
University Of Florida Research Foundation, Incorporated |
Synthetic combinatorial AAV3 capsid library
|
|
WO2017070525A1
(en)
|
2015-10-22 |
2017-04-27 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance in neurodegenerative disease
|
|
EP3364996B1
(en)
|
2015-10-22 |
2021-08-25 |
University of Massachusetts |
Prostate-targeting adeno-associated virus serotype vectors
|
|
EP3368054A4
(en)
|
2015-10-28 |
2019-07-03 |
Voyager Therapeutics, Inc. |
REGULATORY EXPRESSION USING THE ADENO-ASSOCIATED VIRUS (AAV)
|
|
JP2019501115A
(ja)
|
2015-10-28 |
2019-01-17 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
遺伝子治療のためのアデノ随伴ウイルスベクターのくも膜下腔内投与
|
|
WO2017096162A1
(en)
|
2015-12-02 |
2017-06-08 |
Voyager Therapeutics, Inc. |
Assays for the detection of aav neutralizing antibodies
|
|
ES2918998T3
(es)
|
2015-12-11 |
2022-07-21 |
Univ Pennsylvania |
Método de purificación escalable para AAVrh10
|
|
US11098286B2
(en)
|
2015-12-11 |
2021-08-24 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAV9
|
|
US11015173B2
(en)
|
2015-12-11 |
2021-05-25 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for AAV1
|
|
CA3008142A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating familial hypercholesterolemia
|
|
WO2017100676A1
(en)
|
2015-12-11 |
2017-06-15 |
The Trustees Of The University Of Pennsylvania |
Scalable purification method for aav8
|
|
CN116236591B
(zh)
|
2015-12-11 |
2026-02-27 |
马萨诸塞眼科耳科诊所 |
用于将核酸递送至耳蜗和前庭细胞的材料和方法
|
|
AU2016370590B2
(en)
|
2015-12-14 |
2023-11-02 |
The Trustees Of The University Of Pennsylvania |
Composition for treatment of Crigler-Najjar syndrome
|
|
BR112018011881A2
(pt)
|
2015-12-14 |
2018-12-04 |
The University Of North Carolina At Chapel Hill |
proteínas capsidiais modificadas para liberação aumentada de vetores de parvovírus
|
|
WO2017106202A2
(en)
|
2015-12-14 |
2017-06-22 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for ocular disorders
|
|
GB2545763A
(en)
|
2015-12-23 |
2017-06-28 |
Adverum Biotechnologies Inc |
Mutant viral capsid libraries and related systems and methods
|
|
WO2017136536A1
(en)
|
2016-02-02 |
2017-08-10 |
University Of Massachusetts |
Method to enhance the efficiency of systemic aav gene delivery to the central nervous system
|
|
AU2017215211C1
(en)
|
2016-02-03 |
2023-11-16 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating mucopolysaccharidosis type i
|
|
EP3443001B1
(en)
|
2016-04-11 |
2025-04-30 |
Obsidian Therapeutics, Inc. |
REGULATED BIOCIRCUIT SYSTEMS
|
|
EP3443081A4
(en)
|
2016-04-13 |
2019-10-30 |
Duke University |
CRISPR / CAS9-BASED REPRESSORS FOR IN VIVO SHUT-OFF OF GEN-TARGETS AND METHOD OF USE
|
|
AU2017250298B2
(en)
|
2016-04-15 |
2024-10-03 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating mucopolysaccharidosis type II
|
|
CA3019423A1
(en)
*
|
2016-04-15 |
2017-10-19 |
The Trustees Of The University Of Pennsylvania |
Novel aav8 mutant capsids and compositions containing same
|
|
WO2017180936A1
(en)
|
2016-04-15 |
2017-10-19 |
The Trustees Of The University Of Pennsylvania |
Compositions for treatment of wet age-related macular degeneration
|
|
WO2017181105A1
(en)
|
2016-04-15 |
2017-10-19 |
University Of Massachusetts |
Methods and compositions for treating metabolic imbalance
|
|
US11401527B2
(en)
|
2016-04-17 |
2022-08-02 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods useful for prophylaxis of organophosphates
|
|
WO2017189964A2
(en)
|
2016-04-29 |
2017-11-02 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
US11326182B2
(en)
|
2016-04-29 |
2022-05-10 |
Voyager Therapeutics, Inc. |
Compositions for the treatment of disease
|
|
WO2017197355A2
(en)
|
2016-05-13 |
2017-11-16 |
4D Molecular Therapeutics Inc. |
Adeno-associated virus variant capsids and methods of use thereof
|
|
KR20220108216A
(ko)
|
2016-05-18 |
2022-08-02 |
보이저 테라퓨틱스, 인크. |
헌팅톤 질환을 치료하기 위한 조성물 및 방법
|
|
SG11201809699XA
(en)
|
2016-05-18 |
2018-12-28 |
Voyager Therapeutics Inc |
Modulatory polynucleotides
|
|
KR102629418B1
(ko)
|
2016-06-13 |
2024-01-25 |
더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 |
최적화된 cln1 유전자 및 발현 카세트 및 그의 용도
|
|
US11882815B2
(en)
|
2016-06-15 |
2024-01-30 |
University Of Massachusetts |
Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic cells
|
|
KR102799528B1
(ko)
|
2016-07-08 |
2025-04-23 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
Rdh12가 연루된 장애 및 질환의 치료를 위한 방법 및 조성물
|
|
EP4275747A3
(en)
|
2016-07-19 |
2024-01-24 |
Duke University |
Therapeutic applications of cpf1-based genome editing
|
|
US11883470B2
(en)
|
2016-07-25 |
2024-01-30 |
The Trustees Of The University Of Pennsylvania |
Compositions comprising a lecithin cholesterol acyltransferase variant and uses thereof
|
|
AU2017301600B2
(en)
|
2016-07-26 |
2022-08-04 |
Biomarin Pharmaceutical Inc. |
Novel adeno-associated virus capsid proteins
|
|
EP4700118A3
(en)
|
2016-07-29 |
2026-04-22 |
The Regents of the University of California |
Adeno-associated virus virions with varint capsid and methods of use thereof
|
|
IL315358A
(en)
|
2016-08-18 |
2024-11-01 |
Univ California |
CRISPR-CAS genome engineering using a modular AAV delivery system
|
|
CN110650673B
(zh)
|
2016-08-30 |
2024-04-09 |
加利福尼亚大学董事会 |
用于生物医学靶向和递送的方法以及用于实践该方法的装置和系统
|
|
US10457940B2
(en)
|
2016-09-22 |
2019-10-29 |
University Of Massachusetts |
AAV treatment of Huntington's disease
|
|
EP3518985A4
(en)
|
2016-09-29 |
2020-08-05 |
University of Florida Research Foundation, Incorporated |
AAVRH.10 VARIANTS WITH HOST ANTIBODY EXHAUST CAPACITIES AND MODIFIED TISSUE TARGETING PROPERTIES
|
|
CA3040483A1
(en)
|
2016-10-13 |
2018-04-19 |
University Of Massachusetts |
Aav capsid designs
|
|
GB2573406B
(en)
|
2016-10-18 |
2021-11-10 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
|
CA3040179A1
(en)
|
2016-10-19 |
2018-04-26 |
Adverum Biotechnologies, Inc. |
Modified aav capsids and uses thereof
|
|
EP3548065B1
(en)
|
2016-12-01 |
2022-11-09 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Pharmaceutical compositions for the treatment of retinal degenerative diseases
|
|
EP3575398A4
(en)
*
|
2017-01-30 |
2020-11-11 |
Nippon Medical School Foundation |
ADENO-ASSOCIATED VIRUS (AAV) CAPSIDE PROTEIN MUTANT
|
|
MA47436A
(fr)
|
2017-01-31 |
2019-12-11 |
Regenxbio Inc |
Traitement de la mucopolysaccharidose i avec une alpha-l-iduronidase glycosylée entièrement humaine (idua)
|
|
KR20190118163A
(ko)
|
2017-02-20 |
2019-10-17 |
더 트러스티스 오브 더 유니버시티 오브 펜실바니아 |
가족성 고콜레스테롤혈증을 치료하기 위한 유전자 요법
|
|
CA3114549A1
(en)
|
2017-02-21 |
2018-08-30 |
University Of Florida Research Foundation, Incorporated |
Modified aav capsid proteins and uses thereof
|
|
BR112019017697A2
(pt)
|
2017-02-28 |
2020-04-07 |
The Trustees Of The University Of Pennsylvania |
vacinas contra influenza baseadas em vetores de vírus adenoassociado (aav)
|
|
MX2019010275A
(es)
|
2017-02-28 |
2019-10-15 |
Univ Pennsylvania |
Novedoso vector del subtipo f del virus adenoasociado (aav) y usos de este.
|
|
JOP20190200A1
(ar)
|
2017-02-28 |
2019-08-27 |
Univ Pennsylvania |
تركيبات نافعة في معالجة ضمور العضل النخاعي
|
|
KR20230093072A
(ko)
|
2017-03-01 |
2023-06-26 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
안구 장애에 대한 유전자 치료
|
|
CN110831961B
(zh)
|
2017-03-03 |
2024-01-02 |
黑曜石疗法公司 |
用于免疫疗法的cd19组合物和方法
|
|
CN110913954A
(zh)
|
2017-03-03 |
2020-03-24 |
黑曜石疗法公司 |
免疫疗法的组合物和方法
|
|
AU2018253303B2
(en)
|
2017-04-14 |
2024-11-21 |
Regenxbio Inc. |
Treatment of mucopolysaccharidosis II with recombinant human iduronate-2 sulfatase (IDS) produced by human neural or glial cells
|
|
WO2018200542A1
(en)
|
2017-04-24 |
2018-11-01 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for ocular disorders
|
|
JP2020518259A
(ja)
|
2017-05-05 |
2020-06-25 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics,Inc. |
ハンチントン病治療組成物および方法
|
|
SG11201909870SA
(en)
|
2017-05-05 |
2019-11-28 |
Voyager Therapeutics Inc |
Compositions and methods of treating amyotrophic lateral sclerosis (als)
|
|
AU2018265414B2
(en)
|
2017-05-10 |
2022-01-20 |
Massachusetts Eye And Ear Infirmary |
Methods and compositions for modifying assembly-activating protein (APP)-dependence of viruses
|
|
BR112019023303A2
(pt)
|
2017-05-11 |
2020-06-16 |
The Trustees Of The University Of Pennsylvania |
Terapia de gene para lipofuscinoses ceroides neuronais
|
|
CN108103082B
(zh)
*
|
2017-05-11 |
2021-07-13 |
北京锦篮基因科技有限公司 |
一种腺相关病毒介导的lcat基因表达载体及其用途
|
|
KR102765034B1
(ko)
|
2017-05-24 |
2025-02-11 |
유니버시타트 아우토노마 데 바르셀로나 |
섬유아세포 성장 인자 21 (fgf21) 코딩 서열을 포함하는 바이러스 발현 컨스트럭트
|
|
CA3098592A1
(en)
|
2017-05-31 |
2018-12-06 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treating peroxisomal disorders
|
|
US11827898B2
(en)
|
2017-06-14 |
2023-11-28 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for ocular disorders
|
|
JOP20190269A1
(ar)
|
2017-06-15 |
2019-11-20 |
Voyager Therapeutics Inc |
بولي نوكليوتيدات aadc لعلاج مرض باركنسون
|
|
EP3645052A4
(en)
|
2017-06-30 |
2021-07-28 |
Regents of the University of California |
ADENO-ASSOCIATED VIRUS VIRIONS WITH ASSOCIATED CAPSIDE VARIANTS AND METHODS OF USE
|
|
JP2020530307A
(ja)
*
|
2017-06-30 |
2020-10-22 |
インティマ・バイオサイエンス,インコーポレーテッド |
遺伝子治療のためのアデノ随伴ウイルスベクター
|
|
EP3676385A1
(en)
|
2017-07-06 |
2020-07-08 |
The Trustees of The University of Pennsylvania |
Aav9-mediated gene therapy for treating mucopolysaccharidosis type i
|
|
JP7229989B2
(ja)
|
2017-07-17 |
2023-02-28 |
ボイジャー セラピューティクス インコーポレイテッド |
軌道アレイガイドシステム
|
|
TWI832036B
(zh)
|
2017-08-03 |
2024-02-11 |
美商航海家醫療公司 |
用於aav之遞送之組合物及方法
|
|
CA3073937A1
(en)
*
|
2017-08-25 |
2019-02-28 |
Ovid Therapeutics Inc. |
Recombinant adeno-associated vectors
|
|
KR20200039617A
(ko)
|
2017-08-28 |
2020-04-16 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
아데노-연관 바이러스 캡시드 변이체 및 이의 사용 방법
|
|
PE20201264A1
(es)
|
2017-09-20 |
2020-11-19 |
4D Molecular Therapeutics Inc |
Variantes de capsides de virus adenoasociados y metodos de uso de estas
|
|
JP7449223B2
(ja)
|
2017-09-22 |
2024-03-13 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
ムコ多糖症ii型を治療するための遺伝子療法
|
|
MX2020003042A
(es)
|
2017-09-29 |
2020-11-18 |
Voyager Therapeutics Inc |
Rescate del fenotipo neurológico central y periférico de la ataxia de friedreich mediante administración intravenosa.
|
|
US11434502B2
(en)
|
2017-10-16 |
2022-09-06 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (ALS)
|
|
EP4454654A3
(en)
|
2017-10-16 |
2025-02-19 |
Voyager Therapeutics, Inc. |
Treatment of amyotrophic lateral sclerosis (als)
|
|
AU2018350990A1
(en)
|
2017-10-18 |
2020-05-21 |
Regenxbio Inc. |
Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified VEGF-Trap
|
|
AU2018350992A1
(en)
|
2017-10-18 |
2020-05-21 |
Regenxbio Inc. |
Fully-human post-translationally modified antibody therapeutics
|
|
ES2946747T3
(es)
|
2017-11-27 |
2023-07-25 |
4D Molecular Therapeutics Inc |
Variantes de cápsides de virus adenoasociado y su utilización para inhibir la angiogénesis
|
|
EA202091352A1
(ru)
|
2017-11-30 |
2020-08-27 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Генотерапия мукополисахаридоза iiib
|
|
AU2018375164B2
(en)
|
2017-11-30 |
2025-05-15 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for Mucopolysaccharidosis IIIA
|
|
BR112020012336A2
(pt)
|
2017-12-19 |
2021-03-30 |
Akouos, Inc. |
Administração de anticorpos terapêuticos mediada por aav para o ouvido interno
|
|
US10806802B2
(en)
|
2018-01-18 |
2020-10-20 |
University Of Guelph |
Adeno-associated virus particle with mutated capsid and methods of use thereof
|
|
EP3743113B1
(en)
|
2018-01-23 |
2026-04-08 |
Mount Spec Investments Pty Ltd |
Expression vector and method
|
|
AU2019215152A1
(en)
|
2018-02-01 |
2020-08-20 |
Homology Medicines, Inc. |
Adeno-associated virus compositions for restoring PAH gene function and methods of use thereof
|
|
US10610606B2
(en)
|
2018-02-01 |
2020-04-07 |
Homology Medicines, Inc. |
Adeno-associated virus compositions for PAH gene transfer and methods of use thereof
|
|
JP7244547B2
(ja)
|
2018-02-19 |
2023-03-22 |
ホモロジー・メディシンズ・インコーポレイテッド |
F8遺伝子機能を回復させるためのアデノ随伴ウイルス組成物及びその使用の方法
|
|
US12558434B2
(en)
|
2018-02-20 |
2026-02-24 |
The Trustees Of The University Of Pennsylvania |
Compositions for treatment of wet age-related macular degeneration
|
|
IL276859B2
(en)
*
|
2018-02-27 |
2025-12-01 |
Univ Pennsylvania |
Novel adeno-associated virus (aav) vectors, aav vectors having reduced capsid deamidation and uses therefor
|
|
AU2019228504B2
(en)
*
|
2018-02-27 |
2025-06-26 |
The Trustees Of The University Of Pennsylvania |
Novel adeno-associated virus (AAV) vectors, AAV vectors having reduced capsid deamidation and uses therefor
|
|
WO2019191418A1
(en)
*
|
2018-03-29 |
2019-10-03 |
Asklepios Biopharmaceutical, Inc. |
Liver tropic recombinant aav6 vectors that evade neutralization
|
|
WO2019195701A1
(en)
|
2018-04-05 |
2019-10-10 |
Massachusetts Eye And Ear Infirmary |
Methods of making and using combinatorial barcoded nucleic acid libraries having defined variation
|
|
CN112004925B
(zh)
|
2018-04-05 |
2024-09-27 |
吉尼松公司 |
具有降低的肝向性的AAV9和AAVrh74的杂合重组腺相关病毒血清型
|
|
CA3099958A1
(en)
|
2018-04-16 |
2019-10-24 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating duchenne muscular dystrophy
|
|
KR20210009317A
(ko)
|
2018-04-18 |
2021-01-26 |
더 트러스티스 오브 콜롬비아 유니버시티 인 더 시티 오브 뉴욕 |
미토콘드리아 dna 고갈 증후군을 포함하는 불균형 뉴클레오타이드 풀에 의해 초래된 질환에 대한 유전자 요법
|
|
US12365865B2
(en)
|
2018-04-29 |
2025-07-22 |
Regenxbio Inc. |
Scalable clarification process for recombinant AAV production
|
|
EP3788165A1
(en)
|
2018-04-29 |
2021-03-10 |
REGENXBIO Inc. |
Systems and methods of spectrophotometry for the determination of genome content, capsid content and full/empty ratios of adeno-associated virus particles
|
|
IL278393B2
(en)
|
2018-05-08 |
2023-11-01 |
Univ Rutgers |
AAV compatible polymerization proteins bind to laminin
|
|
TW202005978A
(zh)
|
2018-05-14 |
2020-02-01 |
美商拜奧馬林製藥公司 |
新穎肝靶向腺相關病毒載體
|
|
WO2019222329A1
(en)
|
2018-05-15 |
2019-11-21 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
EP3794126A1
(en)
|
2018-05-15 |
2021-03-24 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of parkinson's disease
|
|
US20220403001A1
(en)
|
2018-06-12 |
2022-12-22 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
|
WO2019241486A1
(en)
|
2018-06-13 |
2019-12-19 |
Voyager Therapeutics, Inc. |
Engineered 5' untranslated regions (5' utr) for aav production
|
|
WO2019241535A2
(en)
|
2018-06-14 |
2019-12-19 |
Regenxbio Inc. |
Anion exchange chromatography for recombinant aav production
|
|
GB201811368D0
(en)
|
2018-07-11 |
2018-08-29 |
Ucb Biopharma Sprl |
Antibody
|
|
US11510999B2
(en)
|
2018-07-17 |
2022-11-29 |
Helixmith Co., Ltd |
Treatment of neuropathy with DNA constructs expressing IGF-1 isoforms
|
|
JP2021530548A
(ja)
|
2018-07-24 |
2021-11-11 |
ボイジャー セラピューティクス インコーポレイテッドVoyager Therapeutics, Inc. |
遺伝子治療製剤を生産するための系および方法
|
|
CA3108324A1
(en)
*
|
2018-07-31 |
2020-02-06 |
Cornell University |
Gene therapy methods to control organ function
|
|
US12612644B2
(en)
|
2018-08-10 |
2026-04-28 |
Regenxbio Inc. |
Scalable method for recombinant AAV production
|
|
GB201813528D0
(en)
|
2018-08-20 |
2018-10-03 |
Ucl Business Plc |
Factor IX encoding nucleotides
|
|
US10842885B2
(en)
|
2018-08-20 |
2020-11-24 |
Ucl Business Ltd |
Factor IX encoding nucleotides
|
|
WO2020041498A1
(en)
*
|
2018-08-21 |
2020-02-27 |
Massachusetts Eye And Ear Infirmary |
Compositions and methods for modulating transduction efficiency of adeno-associated viruses
|
|
WO2020047467A2
(en)
|
2018-08-30 |
2020-03-05 |
Tenaya Therapeutics, Inc. |
Cardiac cell reprogramming with myocardin and ascl1
|
|
CN113383010B
(zh)
|
2018-09-28 |
2025-09-09 |
沃雅戈治疗公司 |
具有经工程化改造的启动子的共济蛋白表达构建体及其使用方法
|
|
KR20210082460A
(ko)
|
2018-10-01 |
2021-07-05 |
울트라제닉스 파마수티컬 인코포레이티드 |
프로피온산혈증을 치료하기 위한 유전자 요법
|
|
BR112021006060A2
(pt)
|
2018-10-01 |
2021-07-20 |
The Trustees Of The University Of Pennsylvania |
composições úteis para tratamento de gangliosidose gm1
|
|
TW202035689A
(zh)
|
2018-10-04 |
2020-10-01 |
美商航海家醫療公司 |
測量病毒載體粒子的效價及強度之方法
|
|
JP2022512621A
(ja)
|
2018-10-05 |
2022-02-07 |
ボイジャー セラピューティクス インコーポレイテッド |
Aav産生タンパク質をコードする操作された核酸コンストラクト
|
|
WO2020077165A1
(en)
|
2018-10-12 |
2020-04-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
UY38407A
(es)
|
2018-10-15 |
2020-05-29 |
Novartis Ag |
Anticuerpos estabilizadores de trem2
|
|
EP3867389A1
(en)
|
2018-10-15 |
2021-08-25 |
Voyager Therapeutics, Inc. |
Expression vectors for large-scale production of raav in the baculovirus/sf9 system
|
|
US20210324483A1
(en)
|
2018-10-15 |
2021-10-21 |
Regenxbio Inc. |
Method for measuring the infectivity of replication defective viral vectors and viruses
|
|
WO2020086742A1
(en)
|
2018-10-24 |
2020-04-30 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
|
JP7590968B2
(ja)
|
2018-12-05 |
2024-11-27 |
アビオナ・セラピュ―ティクス・インコーポレイテッド |
遺伝子送達のための組み換えアデノ随伴ウイルスベクター
|
|
SG11202106855YA
(en)
|
2019-01-04 |
2021-07-29 |
Ultragenyx Pharmaceutical Inc |
Gene therapy constructs for treating wilson disease
|
|
MX2021008542A
(es)
|
2019-01-18 |
2021-11-12 |
Voyager Therapeutics Inc |
Métodos y sistemas para la producción de partículas de aav.
|
|
CN113347962B
(zh)
*
|
2019-01-23 |
2025-01-28 |
佛罗里达大学研究基金会有限公司 |
通过合理设计增强的新型aav病毒在视网膜中的高效转导和侧向扩散
|
|
CN113924115A
(zh)
|
2019-01-31 |
2022-01-11 |
俄勒冈健康与科学大学 |
用于aav衣壳的使用转录依赖性定向进化的方法
|
|
MX2021010134A
(es)
|
2019-02-22 |
2021-09-23 |
Univ Pennsylvania |
Virus adenoasociado recombinante para el tratamiento de la neurodegeneracion de inicio en adultos asociada a grn.
|
|
WO2020174369A2
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Compositions and methods to treat bietti crystalline dystrophy
|
|
SG11202108044YA
(en)
|
2019-02-25 |
2021-09-29 |
Novartis Ag |
Compositions and methods to treat bietti crystalline dystrophy
|
|
SG11202108480UA
(en)
|
2019-02-26 |
2021-09-29 |
Univ Pennsylvania |
Compositions useful in treatment of krabbe disease
|
|
JP7637060B2
(ja)
|
2019-03-04 |
2025-02-27 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
Akt経路を標的とする神経保護遺伝子療法
|
|
WO2020205889A1
(en)
|
2019-04-01 |
2020-10-08 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
MX2021011889A
(es)
|
2019-04-03 |
2021-10-26 |
Regenxbio Inc |
Tratamiento genico para patologias oculares.
|
|
TW202102526A
(zh)
|
2019-04-04 |
2021-01-16 |
美商銳進科斯生物股份有限公司 |
重組腺相關病毒及其用途
|
|
US12565645B2
(en)
|
2019-04-11 |
2026-03-03 |
Regenxbio Inc. |
Methods of size exclusion chromatography for the characterization of recombinant adeno-associated virus compositions
|
|
WO2020214929A1
(en)
|
2019-04-19 |
2020-10-22 |
Regenxbio Inc. |
Adeno-associated virus vector formulations and methods
|
|
CA3136872A1
(en)
*
|
2019-04-23 |
2020-10-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
New adeno-associated virus (aav) variants and uses thereof for gene therapy
|
|
TW202106708A
(zh)
|
2019-04-24 |
2021-02-16 |
美商銳進科斯生物股份有限公司 |
全人類轉譯後修飾之抗體治療劑
|
|
EP3752524A4
(en)
*
|
2019-04-27 |
2021-11-24 |
Ocugen, Inc. |
ADENO-ASSOCIATED VIRUS VECTOR MEDIATED GENE THERAPY FOR OPHTHALMIC DISEASE
|
|
MX2021013266A
(es)
*
|
2019-04-29 |
2021-11-17 |
Univ Pennsylvania |
Nuevas capsides de aav y composiciones que las contienen.
|
|
AU2020270421A1
(en)
|
2019-05-03 |
2021-11-18 |
The Trustees Of The University Of Pennsylvania |
Compositions useful in treatment of metachromatic leukodystrophy
|
|
WO2020227515A1
(en)
|
2019-05-07 |
2020-11-12 |
Voyager Therapeutics, Inc. |
Compositions and methods for the vectored augmentation of protein destruction, expression and/or regulation
|
|
EP3914720B9
(en)
|
2019-07-10 |
2023-09-27 |
Masonic Medical Research Laboratory |
Vgll4 with ucp-1 cis-regulatory element and method of use thereof
|
|
EP3997225A1
(en)
|
2019-07-10 |
2022-05-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of epilepsy
|
|
WO2021007515A1
(en)
|
2019-07-11 |
2021-01-14 |
Tenaya Therapeutics, Inc. |
Cardiac cell reprogramming with micrornas and other factors
|
|
KR20220081971A
(ko)
*
|
2019-07-15 |
2022-06-16 |
메이라지티엑스 유케이 Ii 리미티드 |
관절염 질환 치료용 변형된 aav 캡시드 단백질
|
|
US20220396806A1
(en)
|
2019-07-26 |
2022-12-15 |
Akouos, Inc. |
Methods of treating hearing loss using a secreted target protein
|
|
EP4004214A1
(en)
|
2019-07-26 |
2022-06-01 |
RegenxBio Inc. |
Engineered nucleic acid regulatory element and methods of uses thereof
|
|
BR112022003811A2
(pt)
|
2019-08-26 |
2022-11-16 |
Regenxbio Inc |
Tratamento de retinopatia diabética com fab anti vegf totalmente humano modificado pós tradução
|
|
US20230092895A1
(en)
|
2019-08-30 |
2023-03-23 |
Obsidian Therapeutics, Inc. |
Tandem cd19 car-based compositions and methods for immunotherapy
|
|
WO2021046155A1
(en)
|
2019-09-03 |
2021-03-11 |
Voyager Therapeutics, Inc. |
Vectorized editing of nucleic acids to correct overt mutations
|
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
|
KR20220079857A
(ko)
|
2019-09-13 |
2022-06-14 |
루트거스, 더 스테이트 유니버시티 오브 뉴 저지 |
Aav-상용성 라미닌-링커 중합 단백질
|
|
US12544437B2
(en)
|
2019-10-04 |
2026-02-10 |
Ultragenyx Pharmaceutical Inc. |
Methods for improved therapeutic use of recombinant AAV
|
|
CN114728049A
(zh)
|
2019-10-07 |
2022-07-08 |
再生生物股份有限公司 |
腺相关病毒载体药物组合物和方法
|
|
US20220403414A1
(en)
*
|
2019-10-16 |
2022-12-22 |
Wuxi Apptec (Shanghai) Co., Ltd. |
Novel aav variant
|
|
WO2021099394A1
(en)
|
2019-11-19 |
2021-05-27 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antisense oligonucleotides and their use for the treatment of cancer
|
|
US20230270886A1
(en)
|
2019-11-28 |
2023-08-31 |
Regenxbio Inc. |
Microdystrophin gene therapy constructs and uses thereof
|
|
MX2022007135A
(es)
|
2019-12-10 |
2022-09-19 |
Takeda Pharmaceuticals Co |
Vectores de virus adenoasociados para el tratamiento del síndrome de hunter.
|
|
IL293658A
(en)
*
|
2019-12-10 |
2022-08-01 |
Homology Medicines Inc |
Adeno-associated virus preparations and a method of using them
|
|
IL293972A
(en)
|
2019-12-19 |
2022-08-01 |
Univ Pennsylvania |
Preparations for the treatment of Friedrich's ataxia
|
|
IL294278A
(en)
|
2019-12-31 |
2022-08-01 |
Swanbio Therapeutics Ltd |
Improved aav-abcd1 constructs and use for the treatment or prevention of adrenoleukodystrophy (ald) and/or adrenomyeloneuropathy (amn)
|
|
TW202140791A
(zh)
|
2020-01-13 |
2021-11-01 |
美商霍蒙拉奇醫藥公司 |
治療苯酮尿症之方法
|
|
EP4093428A1
(en)
|
2020-01-22 |
2022-11-30 |
RegenxBio Inc. |
Treatment of mucopolysaccharidosis i with fully-human glycosylated human alpha-l-iduronidase (idua)
|
|
TW202142695A
(zh)
|
2020-01-29 |
2021-11-16 |
美商銳進科斯生物股份有限公司 |
用人類神經或神經膠質細胞產生之重組人類艾杜糖醛酸—2—硫酸酯酶(ids)對ii型黏多糖病之治療
|
|
WO2021154956A1
(en)
|
2020-01-29 |
2021-08-05 |
Regenxbio Inc. |
Treatment of mucopolysaccharidosis iva
|
|
CA3165057A1
(en)
|
2020-02-02 |
2021-08-05 |
James M. Wilson |
Compositions useful for treating gm1 gangliosidosis
|
|
BR112022015921A2
(pt)
|
2020-02-14 |
2022-10-04 |
Ultragenyx Pharmaceutical Inc |
Terapia gênica para tratar o transtorno de deficiência de cdkl5
|
|
EP4110792A4
(en)
*
|
2020-02-25 |
2024-08-21 |
Children's Medical Research Institute |
POLYPEPTIDES AND CAPSIDIC VECTORS OF ADENO-ASSOCIATED VIRUSES
|
|
JP2023518415A
(ja)
|
2020-03-19 |
2023-05-01 |
ウルトラジェニックス ファーマシューティカル インコーポレイテッド |
組換えaavにおいてcapおよびrep配列の逆パッケージングを低減するための組成物および方法
|
|
EP4126936A1
(en)
|
2020-03-27 |
2023-02-08 |
UCB Biopharma SRL |
Autonomous knob domain peptides
|
|
US20230129893A1
(en)
|
2020-03-31 |
2023-04-27 |
Ultragenyx Pharmaceutical Inc. |
Gene therapy for treating propionic acidemia
|
|
US20230242940A1
(en)
*
|
2020-04-13 |
2023-08-03 |
Massachusetts Eye And Ear Infirmary |
Methods of making and using a vaccine against coronavirus
|
|
BR112022020753A2
(pt)
|
2020-04-15 |
2022-12-20 |
Voyager Therapeutics Inc |
Compostos de ligação a tau
|
|
CA3177407A1
(en)
|
2020-05-12 |
2021-11-18 |
James M. Wilson |
Compositions for drg-specific reduction of transgene expression
|
|
US20230210941A1
(en)
|
2020-05-12 |
2023-07-06 |
The Trustees Of The University Of Pennsylvania |
Compositions useful in treatment of krabbe disease
|
|
AR122078A1
(es)
|
2020-05-13 |
2022-08-10 |
Akouos Inc |
Composiciones y métodos para tratar la pérdida auditiva asociada a slc26a4
|
|
EP4165194A2
(en)
|
2020-05-13 |
2023-04-19 |
Akouos, Inc. |
Compositions and methods for treating kcnq4-associated hearing loss
|
|
JP2023529315A
(ja)
|
2020-05-26 |
2023-07-10 |
シェイプ セラピューティクス インコーポレイテッド |
機能的aavカプシドのハイスループット工学操作
|
|
TW202208632A
(zh)
|
2020-05-27 |
2022-03-01 |
美商同源醫藥公司 |
用於恢復pah基因功能的腺相關病毒組成物及其使用方法
|
|
WO2021247995A2
(en)
|
2020-06-04 |
2021-12-09 |
Voyager Therapeutics, Inc. |
Compositions and methods of treating neuropathic pain
|
|
JP2023531451A
(ja)
|
2020-06-17 |
2023-07-24 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
遺伝子療法患者の治療のための組成物及び方法
|
|
WO2022003211A1
(en)
*
|
2020-07-03 |
2022-01-06 |
Genethon |
Method for engineering novel hybrid aav capsids through hypervariable regions swapping
|
|
IL299771A
(en)
|
2020-07-10 |
2023-03-01 |
Inst Nat Sante Rech Med |
Methods and compounds for the treatment of epilepsy
|
|
KR20230038503A
(ko)
|
2020-07-13 |
2023-03-20 |
더 트러스티스 오브 더 유니버시티 오브 펜실베니아 |
샤르코-마리-투스 질환의 치료에 유용한 조성물
|
|
BR112023001456A2
(pt)
|
2020-07-27 |
2023-04-11 |
Voyager Therapeutics Inc |
Composições e métodos para o tratamento de distúrbios neurológicos relacionados à deficiência de beta glicosilceramidase
|
|
US20230285596A1
(en)
|
2020-07-27 |
2023-09-14 |
Voyager Therapeutics, Inc |
Compositions and methods for the treatment of niemann-pick type c1 disease
|
|
CN116121275B
(zh)
*
|
2020-07-29 |
2024-11-29 |
北京三诺佳邑生物技术有限责任公司 |
一组肝靶向新型腺相关病毒的获得及其应用
|
|
JP2023536148A
(ja)
|
2020-07-30 |
2023-08-23 |
シェイプ セラピューティクス インク. |
Raavウイルス粒子の誘導産生のための安定な細胞株
|
|
BR112023003310A2
(pt)
|
2020-08-24 |
2023-05-02 |
Univ Pennsylvania |
Vetores virais que codificam fusões de agonistas do receptor de glp-1 e usos dos mesmos no tratamento de doenças metabólicas
|
|
AR123358A1
(es)
|
2020-08-26 |
2022-11-23 |
Univ Pennsylvania |
Virus adenoasociado recombinante para el tratamiento de la neurodegeneración de inicio adulto asociada a la grn
|
|
EP4213890A1
(en)
|
2020-09-15 |
2023-07-26 |
RegenxBio Inc. |
Vectorized lanadelumab and administration thereof
|
|
WO2022060916A1
(en)
|
2020-09-15 |
2022-03-24 |
Regenxbio Inc. |
Vectorized antibodies for anti-viral therapy
|
|
US20230383278A1
(en)
|
2020-09-18 |
2023-11-30 |
The United States Of America,As Represented By The Secretary,Department Of Health And Human Services |
Novel adeno-associated viral (aav) vectors to treat hereditary methylmalonic acidemia (mma) caused by methylmalonyl-coa mutase (mmut) deficiency
|
|
AU2021358048A1
(en)
|
2020-10-07 |
2023-05-25 |
Regenxbio Inc. |
Formulations for suprachoroidal administration such as high viscosity formulations
|
|
WO2022076750A2
(en)
|
2020-10-07 |
2022-04-14 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns or muscle delivery
|
|
IL301947A
(en)
|
2020-10-07 |
2023-06-01 |
Regenxbio Inc |
Formulations for suprachoroidal administration such as gel formulations
|
|
US20230364206A1
(en)
|
2020-10-07 |
2023-11-16 |
Regenxbio Inc. |
Gene therapy for ocular manifestations of cln2 disease
|
|
CA3198368A1
(en)
|
2020-10-07 |
2022-04-14 |
Regenxbio Inc. |
Formulations for suprachoroidal administration such as formulations with aggregate formation
|
|
AU2021356667A1
(en)
|
2020-10-07 |
2023-06-08 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
JP7415042B2
(ja)
|
2020-10-09 |
2024-01-16 |
テナヤ セラピューティクス, インコーポレイテッド |
プラコフィリン2遺伝子治療の方法および組成物
|
|
AU2021356684A1
(en)
|
2020-10-09 |
2023-05-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of fabry disease
|
|
US11781156B2
(en)
|
2020-10-09 |
2023-10-10 |
Tenaya Therapeutics, Inc. |
Plakophillin-2 gene therapy methods and compositions
|
|
CA3195553A1
(en)
|
2020-10-18 |
2022-04-21 |
Qiang Wang |
Improved adeno-associated virus (aav) vector and uses therefor
|
|
WO2022094157A1
(en)
|
2020-10-28 |
2022-05-05 |
Regenxbio Inc. |
Vectorized anti-cgrp and anti-cgrpr antibodies and administration thereof
|
|
JP2023547832A
(ja)
|
2020-10-28 |
2023-11-14 |
リジェネックスバイオ インコーポレイテッド |
眼の適応症に対するベクター化抗TNF-α抗体
|
|
WO2022094078A1
(en)
|
2020-10-28 |
2022-05-05 |
The Trustees Of The University Of Pennsylvania |
Compositions useful in treatment of rett syndrome
|
|
EP4236974A2
(en)
|
2020-10-29 |
2023-09-06 |
RegenxBio Inc. |
Vectorized factor xii antibodies and administration thereof
|
|
EP4237453A1
(en)
|
2020-10-29 |
2023-09-06 |
RegenxBio Inc. |
Vectorized tnf-alpha antagonists for ocular indications
|
|
MX2023006445A
(es)
|
2020-12-01 |
2023-08-10 |
Univ Pennsylvania |
Composiciones y usos de estas para el tratamiento del síndrome de angelman.
|
|
IL303317A
(en)
|
2020-12-01 |
2023-07-01 |
Akouos Inc |
ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA
|
|
AR124216A1
(es)
|
2020-12-01 |
2023-03-01 |
Univ Pennsylvania |
Composiciones nuevas con motivos selectivos específicos del tejido y composiciones que las contienen
|
|
JP2023554389A
(ja)
|
2020-12-16 |
2023-12-27 |
リジェネクスバイオ インコーポレイテッド |
組換えアデノ随伴ウイルスウイルス粒子を生成する方法
|
|
US20240309076A1
(en)
|
2020-12-29 |
2024-09-19 |
Regenxbio Inc. |
Tau-specific antibody gene therapy compositions, methods and uses thereof
|
|
KR20230127263A
(ko)
|
2020-12-29 |
2023-08-31 |
아카우오스, 인크. |
Clrn1-연관된 청력손실 및/또는 시력손실을 치료하기위한 조성물 및 방법
|
|
WO2022155500A1
(en)
|
2021-01-14 |
2022-07-21 |
Senti Biosciences, Inc. |
Secretable payload regulation
|
|
JP2024503895A
(ja)
|
2021-01-21 |
2024-01-29 |
リジェネクスバイオ インコーポレイテッド |
組換えポリペプチド及びウイルスの生成の改善
|
|
EP4284335A1
(en)
|
2021-02-01 |
2023-12-06 |
RegenxBio Inc. |
Gene therapy for neuronal ceroid lipofuscinoses
|
|
EP4288553A4
(en)
|
2021-02-02 |
2025-06-25 |
University of Massachusetts |
INVERTED TERMINAL REPEAT SEQUENCES OF AAV SEROTYPES 8 AND RH.39 IN GENE THERAPY VECTORS
|
|
BR112023016075A2
(pt)
|
2021-02-10 |
2023-11-21 |
Regenxbio Inc |
Método para tratar hepatoesplenomegalia, método de distribuição de um raav que codifica hids, método para tratar um sujeito humano, método de tratamento de um sujeito humano, método para determinar a eficácia do tratamento, método para identificar um sujeito como tendo mps ii
|
|
WO2022183052A1
(en)
|
2021-02-26 |
2022-09-01 |
Takeda Pharmaceutical Company Limited |
Composition and methods for the treatment of fabry disease
|
|
AU2022258312A1
(en)
|
2021-04-12 |
2023-10-26 |
The Trustees Of The University Of Pennsylvania |
Compositions useful for treating spinal and bulbar muscular atrophy (sbma)
|
|
US20240181084A1
(en)
|
2021-04-23 |
2024-06-06 |
University Of Rochester |
Genome Editing by Directed Non-Homologous DNA Insertion Using a Retroviral Integrase-Cas Fusion Protein and Methods of Treatment
|
|
MX2023012513A
(es)
|
2021-04-23 |
2023-12-15 |
Univ Pennsylvania |
Nuevas composiciones con motivos selectivos para el cerebro y composiciones que las contienen.
|
|
US20240216543A1
(en)
|
2021-04-26 |
2024-07-04 |
Regenxbio Inc. |
Microdystrophin gene therapy administration for treatment of dystrophinopathies
|
|
WO2022235614A2
(en)
|
2021-05-04 |
2022-11-10 |
Regenxbio Inc. |
Novel aav vectors and methods and uses thereof
|
|
US20240358857A1
(en)
|
2021-05-11 |
2024-10-31 |
Regenxbio Inc. |
Treatment of duchenne muscular dystrophy and combinations thereof
|
|
WO2022272297A1
(en)
|
2021-06-25 |
2022-12-29 |
Oxford Biomedica Solutions Llc |
Adeno-associated virus packaging systems
|
|
AU2022301302A1
(en)
|
2021-07-01 |
2024-01-25 |
Indapta Therapeutics, Inc. |
Engineered natural killer (nk) cells and related methods
|
|
US20240409955A1
(en)
|
2021-07-19 |
2024-12-12 |
New York University |
Auf1 combination therapies for treatment of muscle degenerative disease
|
|
JP2024531138A
(ja)
|
2021-08-11 |
2024-08-29 |
ウルトラジェニックス ファーマシューティカル インコーポレイテッド |
筋ジストロフィーを処置するための組成物および方法
|
|
AU2022325955A1
(en)
|
2021-08-11 |
2024-02-08 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions
|
|
WO2023019226A1
(en)
|
2021-08-11 |
2023-02-16 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy
|
|
JP2024531234A
(ja)
|
2021-08-11 |
2024-08-29 |
サナ バイオテクノロジー,インコーポレイテッド |
同種異系細胞療法のための遺伝子改変された初代細胞
|
|
JP2024534771A
(ja)
|
2021-08-11 |
2024-09-26 |
サナ バイオテクノロジー,インコーポレイテッド |
補体媒介性炎症反応を低減するための同種異系細胞療法のための遺伝子改変細胞
|
|
US20230076072A1
(en)
|
2021-08-24 |
2023-03-09 |
Oxford Biomedica Solutions Llc |
Adeno-associated virus formulations
|
|
CA3230004A1
(en)
*
|
2021-08-25 |
2023-03-02 |
Yunxiang Zhu |
Aav particles comprising liver-tropic capsid protein and acid alpha-glucosidase and use to treat pompe disease
|
|
IL311096A
(en)
|
2021-08-31 |
2024-04-01 |
Scout Bio Inc |
Antigen binding molecules and their uses
|
|
AU2022356427A1
(en)
|
2021-09-30 |
2024-05-09 |
Akouos, Inc. |
Compositions and methods for treating kcnq4-associated hearing loss
|
|
TW202325845A
(zh)
|
2021-10-02 |
2023-07-01 |
賓州大學委員會 |
新穎aav衣殼及含其之組成物
|
|
CN118202060A
(zh)
|
2021-10-05 |
2024-06-14 |
再生生物股份有限公司 |
用于重组aav生产的组合物和方法
|
|
WO2023060113A1
(en)
|
2021-10-05 |
2023-04-13 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
EP4413019A2
(en)
|
2021-10-07 |
2024-08-14 |
RegenxBio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
EP4413018A1
(en)
|
2021-10-07 |
2024-08-14 |
RegenxBio Inc. |
Recombinant adeno-associated viruses for targeted delivery
|
|
WO2023077092A1
(en)
|
2021-10-28 |
2023-05-04 |
Regenxbio Inc. |
Engineered nucleic acid regulatory elements and methods and uses thereof
|
|
WO2023072181A1
(en)
*
|
2021-10-28 |
2023-05-04 |
Shanghai Vitalgen Biopharma Co., Ltd. |
Adeno-associated virus capsid
|
|
US20230183659A1
(en)
|
2021-10-29 |
2023-06-15 |
Homology Medicines, Inc. |
Methods and compositions for the purification of adeno-associated virus
|
|
WO2023087019A2
(en)
|
2021-11-15 |
2023-05-19 |
The Trustees Of The University Of Pennsylvania |
Compositions for drg-specific reduction of transgene expression
|
|
CA3238867A1
(en)
|
2021-11-29 |
2023-06-01 |
Shanghai Regenelead Therapies Co., Ltd. |
Aadc/gdnf polynucleotide, and use thereof in treating parkinson's disease
|
|
AU2022401548A1
(en)
|
2021-12-01 |
2024-07-04 |
Shape Therapeutics Inc. |
Functional aav capsids for systemic administration
|
|
KR20240128717A
(ko)
|
2021-12-01 |
2024-08-26 |
셰이프 테라퓨틱스 인코포레이티드 |
유리체내 투여용 기능성 aav 캡시드
|
|
US20240408157A1
(en)
|
2021-12-02 |
2024-12-12 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of fabry disease
|
|
CN118510905A
(zh)
*
|
2021-12-06 |
2024-08-16 |
学校法人顺天堂 |
改变型腺伴随病毒载体
|
|
US20230323395A1
(en)
|
2021-12-15 |
2023-10-12 |
Homology Medicines, Inc. |
Methods and compositions for the production of adeno-associated virus
|
|
TW202340467A
(zh)
|
2022-01-10 |
2023-10-16 |
賓州大學委員會 |
有用於治療c9orf72介導之病症之組成物及方法
|
|
TW202338086A
(zh)
|
2022-01-10 |
2023-10-01 |
賓州大學委員會 |
有用於治療異染性白質失養症之組成物
|
|
WO2023133595A2
(en)
|
2022-01-10 |
2023-07-13 |
Sana Biotechnology, Inc. |
Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
|
|
WO2023147304A1
(en)
|
2022-01-25 |
2023-08-03 |
The Trustees Of The University Of Pennsylvania |
Aav capsids for improved heart transduction and detargeting of liver
|
|
WO2023150647A1
(en)
|
2022-02-02 |
2023-08-10 |
Sana Biotechnology, Inc. |
Methods of repeat dosing and administration of lipid particles or viral vectors and related systems and uses
|
|
EP4473011A1
(en)
|
2022-02-02 |
2024-12-11 |
Akouos, Inc. |
Anti-vegf antibody constructs and related methods for treating vestibular schwannoma associated symptoms
|
|
JP2025508720A
(ja)
|
2022-02-17 |
2025-04-10 |
サナ バイオテクノロジー,インコーポレイテッド |
遺伝子操作されたcd47タンパク質及びその使用関連出願の相互参照
|
|
CN118660913A
(zh)
|
2022-02-21 |
2024-09-17 |
上海瑞宏迪医药有限公司 |
Vegf结合分子及其医药用途
|
|
JP2025509328A
(ja)
|
2022-03-07 |
2025-04-11 |
ウルトラジェニックス ファーマシューティカル インコーポレイテッド |
改良されたバッチaav産生システムおよび方法
|
|
US20250101382A1
(en)
|
2022-03-11 |
2025-03-27 |
Sana Biotechnology, Inc. |
Genetically modified cells and compositions and uses thereof
|
|
WO2023178053A1
(en)
|
2022-03-13 |
2023-09-21 |
Regenxbio Inc. |
Modified muscle-specific promoters
|
|
EP4499154A1
(en)
|
2022-03-25 |
2025-02-05 |
REGENXBIO Inc. |
Dominant-negative tumor necrosis factor alpha adeno-associated virus gene therapy
|
|
WO2023187728A1
(en)
|
2022-04-01 |
2023-10-05 |
Takeda Pharmaceutical Company Limited |
Gene therapy for diseases with cns manifestations
|
|
CA3247507A1
(en)
|
2022-04-06 |
2023-10-12 |
Regenxbio Inc. |
PHARMACEUTICAL COMPOSITION COMPRISING A RECOMMENDED ADENO-ASSOCIATED VIRUS (AAV) VECTOR WITH AN EXPRESSION CASSETTE ENCODED BY A TRANSGENE FOR SUPRACHOROID ADMINISTRATION
|
|
TW202404651A
(zh)
|
2022-04-06 |
2024-02-01 |
美商銳進科斯生物股份有限公司 |
用於脈絡膜上投與之調配物諸如形成聚集體之調配物
|
|
WO2023196892A1
(en)
|
2022-04-06 |
2023-10-12 |
The Trustees Of The University Of Pennsylvania |
Passive immunization with anti- aav neutralizing antibodies to prevent off-target transduction of intrathecally delivered aav vectors
|
|
TW202345913A
(zh)
|
2022-04-06 |
2023-12-01 |
美商銳進科斯生物股份有限公司 |
用於脈絡膜上投與之調配物諸如凝膠調配物
|
|
WO2023196893A1
(en)
|
2022-04-06 |
2023-10-12 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating her2 positive metastatic breast cancer and other cancers
|
|
WO2023201277A1
(en)
|
2022-04-14 |
2023-10-19 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
US20250249127A1
(en)
|
2022-04-14 |
2025-08-07 |
Regenxbio Inc. |
Gene therapy for treating an ocular disease
|
|
WO2023215807A1
(en)
|
2022-05-03 |
2023-11-09 |
Regenxbio Inc. |
VECTORIZED ANTI-TNF-α INHIBITORS FOR OCULAR INDICATIONS
|
|
WO2023215806A2
(en)
|
2022-05-03 |
2023-11-09 |
Regenxbio Inc. |
Vectorized anti-complement antibodies and complement agents and administration thereof
|
|
JP2025517628A
(ja)
|
2022-05-06 |
2025-06-10 |
ノバルティス アーゲー |
新規の組換えaav vp2融合ポリペプチド
|
|
WO2023239627A2
(en)
|
2022-06-08 |
2023-12-14 |
Regenxbio Inc. |
Methods for recombinant aav production
|
|
KR20250044484A
(ko)
|
2022-06-24 |
2025-03-31 |
튠 쎄라퓨틱스, 인코포레이티드 |
표적 유전자 억제를 통해 저밀도 지단백질을 감소시키기 위한 조성물, 시스템, 및 방법
|
|
CN120051297A
(zh)
|
2022-06-30 |
2025-05-27 |
因达普塔治疗公司 |
工程化自然杀伤(nk)细胞与抗体疗法的组合及相关方法
|
|
WO2024017990A1
(en)
|
2022-07-21 |
2024-01-25 |
Institut National de la Santé et de la Recherche Médicale |
Methods and compositions for treating chronic pain disorders
|
|
US20260027145A1
(en)
|
2022-07-27 |
2026-01-29 |
Sana Biotechnology, Inc. |
Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
|
|
US20260055144A1
(en)
|
2022-08-24 |
2026-02-26 |
Regenxbio Inc. |
Recombinant adeno-associated viruses and uses thereof
|
|
CA3264923A1
(en)
|
2022-08-25 |
2024-02-29 |
Takeda Pharmaceutical Company Limited |
COMPOSITION INTENDED FOR USE IN THE TREATMENT OF FABRY'S DISEASE
|
|
EP4593955A1
(en)
|
2022-09-30 |
2025-08-06 |
RegenxBio Inc. |
Treatment of ocular diseases with recombinant viral vectors encoding anti-vegf fab
|
|
CN115960177B
(zh)
*
|
2022-10-09 |
2023-07-07 |
广州派真生物技术有限公司 |
腺相关病毒突变体及其应用
|
|
JP2025534666A
(ja)
|
2022-10-11 |
2025-10-17 |
リジェネックスバイオ インコーポレイテッド |
操作された核酸調節エレメントならびにその使用方法
|
|
WO2024105638A1
(en)
|
2022-11-18 |
2024-05-23 |
Jcr Pharmaceuticals Co., Ltd. |
Recombinant aav vectors and methods for treatment of hunter syndrome
|
|
CN116789738B
(zh)
*
|
2022-12-08 |
2023-12-19 |
广州派真生物技术有限公司 |
腺相关病毒突变体及其应用
|
|
WO2024130067A2
(en)
|
2022-12-17 |
2024-06-20 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav mutant vectors with cardiac and skeletal muscle-specific targeting motifs and compositions containing same
|
|
WO2024130070A2
(en)
|
2022-12-17 |
2024-06-20 |
The Trustees Of The University Of Pennsylvania |
Recombinant aav capsids with cardiac- and skeletal muscle- specific targeting motifs and uses thereof
|
|
IT202200026595A1
(it)
|
2022-12-22 |
2024-06-22 |
Fond Telethon Ets |
Nuovi inibitori di regolatori epigenetici
|
|
CN120752339A
(zh)
|
2023-01-06 |
2025-10-03 |
国家医疗保健研究所 |
静脉内施用用于治疗疼痛的反义寡核苷酸
|
|
WO2024151541A1
(en)
|
2023-01-09 |
2024-07-18 |
Sana Biotechnology, Inc. |
Type-1 diabetes autoimmune mouse
|
|
AU2023427408A1
(en)
|
2023-02-02 |
2025-09-04 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of neurological disorders related to glucosylceramidase beta deficiency
|
|
EP4680741A2
(en)
|
2023-03-15 |
2026-01-21 |
RegenxBio Inc. |
Exon skipping gene therapy constructs, vectors and uses thereof
|
|
WO2024211780A1
(en)
|
2023-04-07 |
2024-10-10 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
WO2024216244A2
(en)
|
2023-04-13 |
2024-10-17 |
Regenxbio Inc. |
Targeting aav capsids, methods of manufacturing and using same
|
|
AU2024264889A1
(en)
|
2023-05-03 |
2025-11-13 |
Sana Biotechnology, Inc. |
Methods of dosing and administration of engineered islet cells
|
|
AU2024266138A1
(en)
|
2023-05-03 |
2025-11-13 |
Manifold Biotechnologies, Inc. |
Methods and compositions for high-throughput protein delivery, screening, and detection
|
|
WO2024233529A2
(en)
|
2023-05-07 |
2024-11-14 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
WO2024233999A2
(en)
|
2023-05-11 |
2024-11-14 |
University Hospitals Cleveland Medical Center |
Anxiolytic therapy
|
|
WO2024238853A1
(en)
|
2023-05-16 |
2024-11-21 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
AU2024271004A1
(en)
|
2023-05-16 |
2026-01-15 |
Regenxbio Inc. |
Vectorized anti-complement antibodies and administration thereof
|
|
WO2024238859A1
(en)
|
2023-05-16 |
2024-11-21 |
Regenxbio Inc. |
Vectorized c5 inhibitor agents and administration thereof
|
|
CN121604968A
(zh)
|
2023-05-22 |
2026-03-03 |
萨那生物科技公司 |
递送胰岛细胞的方法及相关方法
|
|
WO2024241176A1
(en)
|
2023-05-24 |
2024-11-28 |
Jcr Pharmaceuticals Co., Ltd. |
Recombinant aav vectors and methods for treatment of diseases with central nervous system disorders
|
|
EP4724085A1
(en)
|
2023-06-12 |
2026-04-15 |
The Trustees of The University of Pennsylvania |
Aav gene therapy for mucopolysaccharidosis iiib
|
|
AR133098A1
(es)
|
2023-06-29 |
2025-08-27 |
Univ Pennsylvania |
Aav mutante con motivos dirigidos al sistema nervioso central y composiciones que lo contienen
|
|
WO2025008406A1
(en)
|
2023-07-04 |
2025-01-09 |
Institut National de la Santé et de la Recherche Médicale |
Antisense oligonucleotides and their use for the treatment of cancer
|
|
WO2025035143A1
(en)
|
2023-08-10 |
2025-02-13 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of spinal muscular atrophy
|
|
TW202508610A
(zh)
|
2023-08-23 |
2025-03-01 |
大陸商上海瑞宏迪醫藥有限公司 |
醫藥組成物及其用途
|
|
WO2025075963A1
(en)
|
2023-10-02 |
2025-04-10 |
Regenxbio Inc. |
Methods and formulations for treating mucopolysaccharidosis ii-associated hearing loss with recombinant human iduronate-2-sulfatase
|
|
WO2025082618A1
(en)
|
2023-10-20 |
2025-04-24 |
Fuse Vectors Aps |
In vitro parvovirus capsid manufacturing
|
|
WO2025090962A1
(en)
|
2023-10-25 |
2025-05-01 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
WO2025090858A1
(en)
|
2023-10-27 |
2025-05-01 |
Biogen Ma Inc. |
Methods for identifying aav capsid variants with desired characteristics
|
|
WO2025102034A1
(en)
|
2023-11-10 |
2025-05-15 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for barth syndrome
|
|
WO2025106374A1
(en)
|
2023-11-13 |
2025-05-22 |
Juno Therapeutics, Inc. |
Aav production method
|
|
WO2025106661A1
(en)
|
2023-11-14 |
2025-05-22 |
The Trustees Of The University Of Pennsylvania |
Compositions with cardiac and skeletal musclespecific targeting motifs and uses thereof
|
|
WO2025108407A2
(en)
|
2023-11-23 |
2025-05-30 |
Neuexcell Therapeutics (Suzhou) Co., Ltd. |
Gene therapy compositions and methods for treating glioma
|
|
WO2025113676A1
(en)
|
2023-11-29 |
2025-06-05 |
Neuexcell Therapeutics (Suzhou) Co., Ltd. |
Compositions and methods for treating stroke in primates
|
|
WO2025129157A1
(en)
|
2023-12-15 |
2025-06-19 |
The Trustees Of The University Of Pennsylvania |
Gene therapy for treatment of canavan disease
|
|
TW202548022A
(zh)
|
2024-03-03 |
2025-12-16 |
美商帕西奇生物公司 |
用於治療神經退化性病症之重組腺相關病毒
|
|
TW202603165A
(zh)
|
2024-03-04 |
2026-01-16 |
美商凱特治療公司 |
用於治療杜興氏肌肉失養症之腺相關病毒組成物
|
|
WO2025217230A1
(en)
|
2024-04-08 |
2025-10-16 |
Regenxbio Inc. |
Vectorized anti-complement antibodies and complement agents and administration thereof
|
|
WO2025217214A2
(en)
|
2024-04-08 |
2025-10-16 |
Regenxbio Inc. |
Recombinant adeno-associated viruses and uses thereof
|
|
WO2025226841A1
(en)
|
2024-04-24 |
2025-10-30 |
Kate Therapeutics, Inc. |
Gene therapy approach for treating disorders associated with tnnt2
|
|
WO2025226842A1
(en)
|
2024-04-24 |
2025-10-30 |
Kate Therapeutics, Inc. |
Expression control by drg-expressed mirnas
|
|
WO2025237990A1
(en)
|
2024-05-14 |
2025-11-20 |
Institut National de la Santé et de la Recherche Médicale |
Antisense oligonucleotides and their use for the treatment of pulmonary fibrosis
|
|
WO2026006341A1
(en)
|
2024-06-24 |
2026-01-02 |
Regenxbio Inc. |
Microdystrophin gene therapy administration for treatment of dystrophinopathies
|
|
WO2026011009A1
(en)
|
2024-07-02 |
2026-01-08 |
Kate Therapeutics, Inc. |
Compositions and methods for muscle disorders
|
|
WO2026011008A1
(en)
|
2024-07-02 |
2026-01-08 |
Kate Therapeutics, Inc. |
Expression control by skeletal muscle-expressed mirnas
|
|
CN118460614B
(zh)
*
|
2024-07-05 |
2025-03-11 |
凌意(杭州)生物科技有限公司 |
一种腺相关病毒Cap蛋白的表达框
|
|
WO2026030242A1
(en)
|
2024-07-29 |
2026-02-05 |
Kate Therapeutics, Inc. |
Adeno-associated virus compositions for the treatment of facioscapulohumeral muscular dystrophy
|
|
WO2026030244A1
(en)
|
2024-07-30 |
2026-02-05 |
Kate Therapeutics, Inc. |
Adeno-associated virus compositions for the treatment of limb girdle muscular dystrophy 2a
|
|
WO2026036118A1
(en)
|
2024-08-09 |
2026-02-12 |
Shape Therapeutics Inc. |
Engineered aav capsid polypeptides and methods of use
|
|
WO2026044087A1
(en)
|
2024-08-21 |
2026-02-26 |
Shape Therapeutics Inc. |
Increased cellular stability for aav production
|
|
WO2026050402A1
(en)
|
2024-08-29 |
2026-03-05 |
Kate Therapeutics, Inc. |
Liver de-targeted muscle tropic capsids
|
|
CN118754952B
(zh)
*
|
2024-09-06 |
2025-01-10 |
上海玮美基因科技有限责任公司 |
一种新型腺相关病毒及其应用
|
|
WO2026073032A1
(en)
|
2024-09-27 |
2026-04-02 |
Shape Therapeutics Inc. |
Constructs for improved aav production
|
|
WO2026094009A1
(en)
|
2024-11-04 |
2026-05-07 |
Insmed Incorporated |
Compositions and methods for treating duchenne muscular dystrophy
|