|
US530579A
(en)
*
|
|
1894-12-11 |
|
Side bearing for cars |
|
US5043270A
(en)
|
1989-03-31 |
1991-08-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Intronic overexpression vectors
|
|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5399363A
(en)
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
EP0755454B1
(en)
|
1994-04-13 |
2008-02-13 |
The Rockefeller University |
Aav-mediated delivery of dna to cells of the nervous system
|
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
|
IE80468B1
(en)
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
|
US6391607B1
(en)
|
1996-06-14 |
2002-05-21 |
Genentech, Inc. |
Human DNase I hyperactive variants
|
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
|
JP2001500015A
(ja)
|
1996-09-06 |
2001-01-09 |
トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
T7ポリメラーゼを利用する組換えアデノ随伴ウイルスの誘導可能な製造方法
|
|
WO1998010087A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Chimpanzee adenovirus vectors
|
|
US6177403B1
(en)
|
1996-10-21 |
2001-01-23 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US6475469B1
(en)
|
1996-11-21 |
2002-11-05 |
Applied Dental Sciences, Inc. |
Compositions for removing tooth stains
|
|
WO1998024479A1
(en)
|
1996-12-02 |
1998-06-11 |
Cell Genesys, Inc. |
Adeno-associated viral vector-mediated delivery of dna to cells of the liver
|
|
US6156303A
(en)
*
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
JP2001517454A
(ja)
|
1997-09-19 |
2001-10-09 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスの産生に有用な方法および細胞株
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
WO1999061066A2
(en)
|
1998-05-27 |
1999-12-02 |
Avigen, Inc. |
Convection-enhanced delivery of aav vectors
|
|
AU762220B2
(en)
|
1998-05-28 |
2003-06-19 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
AAV5 vector and uses thereof
|
|
CA2335390A1
(en)
|
1998-07-22 |
2000-02-03 |
Immusol Incorporated |
Substantially complete ribozyme libraries
|
|
US20030110526A1
(en)
|
1998-08-25 |
2003-06-12 |
Robert H. Brown |
Dysferlin mutations
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
WO2001029243A1
(en)
|
1999-10-15 |
2001-04-26 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
US6821512B1
(en)
|
1999-12-03 |
2004-11-23 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for increasing packaging and yield of recombinant adenoviruses using multiple packaging signals
|
|
US7638120B2
(en)
*
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
US7749492B2
(en)
*
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
US20040136963A1
(en)
|
2001-06-22 |
2004-07-15 |
The Trustees Of The University Of Pennsylvania |
Simian adenovirus vectors and methods of use
|
|
AU2002322285A1
(en)
|
2001-06-22 |
2003-01-08 |
The Trustees Of The University Of Pennsylvania |
Method for rapid screening of bacterial transformants and novel simian adenovirus proteins
|
|
WO2003004660A1
(en)
|
2001-07-03 |
2003-01-16 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of administering vectors to synaptically connected neurons
|
|
JP2004534543A
(ja)
|
2001-07-13 |
2004-11-18 |
ユニバーシテイ・オブ・アイオワ・リサーチ・フアウンデーシヨン |
シュードタイプ化アデノ関連ウイルスおよびその使用
|
|
US20030050273A1
(en)
|
2001-08-29 |
2003-03-13 |
Keiya Ozawa |
Compositions and methods for treating neurodegenerative diseases
|
|
US20030092161A1
(en)
|
2001-09-19 |
2003-05-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for production of recombinant viruses, and uses therefor
|
|
SG10202108118RA
(en)
|
2001-11-13 |
2021-08-30 |
Univ Pennsylvania |
A method of detecting and/or identifying adeno-associated virus (aav) sequences and isolating novel sequences identified thereby
|
|
HU230364B1
(hu)
|
2001-11-21 |
2016-03-29 |
The Trustees Of The University Of Pennsylvania |
Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására
|
|
ES2975413T3
(es)
|
2001-12-17 |
2024-07-05 |
Univ Pennsylvania |
Secuencias de serotipo 8 de virus adenoasociado (AAV), vectores que las contienen y usos de las mismas
|
|
ES2526341T3
(es)
|
2001-12-17 |
2015-01-09 |
The Trustees Of The University Of Pennsylvania |
Secuencias de serotipo 9 de virus adeno-asociado (AAV), vectores que las contienen, y usos de las mismas
|
|
US20050137153A1
(en)
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
|
US20060292117A1
(en)
|
2002-04-17 |
2006-12-28 |
Loiler Scott A |
Improved rAAv vectors
|
|
AU2003221745A1
(en)
|
2002-04-19 |
2003-11-03 |
University Of Florida |
rAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES
|
|
WO2003093460A1
(en)
|
2002-04-29 |
2003-11-13 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20050255086A1
(en)
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
US20050143330A1
(en)
|
2002-09-30 |
2005-06-30 |
Ron Mandel |
Method for the treatment of Parkinson's Disease
|
|
AU2004208031B2
(en)
|
2003-01-28 |
2009-10-08 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
|
|
US7387896B2
(en)
|
2003-03-26 |
2008-06-17 |
The Regents Of The University Of Michigan |
MicroRNA vectors
|
|
WO2004108922A2
(en)
|
2003-04-25 |
2004-12-16 |
The Trustees Of The University Of Pennsylvania |
Use of aav comprising a capsid protein from aav7 or aav8 for the delivery of genes encoding apoprotein a or e genes to the liver
|
|
US20060228800A1
(en)
|
2003-05-15 |
2006-10-12 |
Shi-Lung Lin |
Novel Transgenic Methods Using intronic RNA
|
|
ES2712695T3
(es)
|
2003-06-02 |
2019-05-14 |
Univ Massachusetts |
Métodos y composiciones para controlar la eficacia de la silenciación del ARN
|
|
HUE054805T2
(hu)
|
2003-09-30 |
2021-09-28 |
Univ Pennsylvania |
Adeno-asszociált vírus (AAV) kládok, szekvenciák, az azokat tartalmazó vektorok és alkalmazásaik
|
|
KR101246862B1
(ko)
|
2004-03-05 |
2013-03-27 |
베니텍 리미티드 |
RNAi 제제의 동시 전달을 위한 다중 프로모터 발현카세트
|
|
US7498316B2
(en)
|
2004-04-06 |
2009-03-03 |
University Of Massachusetts |
Methods and compositions for treating gain-of-function disorders using RNA interference
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
US20060073119A1
(en)
|
2004-09-01 |
2006-04-06 |
Avigen, Inc. |
Methods for treating neurodegenerative disorders
|
|
CN101213305A
(zh)
*
|
2004-12-09 |
2008-07-02 |
建新公司 |
转基因在哺乳动物中枢神经系统中的可调控型表达
|
|
AU2005316476A1
(en)
*
|
2004-12-15 |
2006-06-22 |
University Of Florida Research Foundation, Inc. |
Chimeric vectors
|
|
CN101180394B
(zh)
|
2005-02-03 |
2013-01-09 |
贝尼泰克有限公司 |
RNAi表达构建体
|
|
ATE524546T1
(de)
|
2005-03-25 |
2011-09-15 |
Medtronic Inc |
Verwendung von anti-tnf oder anti-il1-rnai zur unterdrückung der wirkung entzündungsfördernder cytokine zur lokalen schmerzbehandlung
|
|
EP3085389A1
(en)
|
2005-04-07 |
2016-10-26 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an aav vector
|
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
|
CA2606362A1
(en)
|
2005-04-29 |
2006-11-09 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for regulated expression of nucleic acid at post-transcriptional level
|
|
ES2564823T3
(es)
|
2005-05-27 |
2016-03-29 |
Ospedale San Raffaele S.R.L. |
Vector génico que comprende miARN
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
WO2007027775A2
(en)
|
2005-08-29 |
2007-03-08 |
Isis Pharmaceuticals, Inc. |
Methods for use in modulating mir-122a
|
|
EP2484782B1
(en)
|
2006-01-05 |
2015-11-18 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
WO2008016391A2
(en)
|
2006-01-31 |
2008-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
ES2700048T3
(es)
|
2006-02-08 |
2019-02-13 |
Genzyme Corp |
Terapia génica par la enfermedad de Niemann-Pick tipo A
|
|
DK2514823T3
(en)
|
2006-03-03 |
2018-07-23 |
Promis Neurosciences Inc |
Methods and compositions for treating and detecting failed SOD1-mediated diseases
|
|
WO2007120542A2
(en)
|
2006-03-30 |
2007-10-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Aav capsid library and aav capsid proteins
|
|
US9198984B2
(en)
|
2006-04-28 |
2015-12-01 |
The Trustees Of The University Of Pennsylvania |
Scalable production method for AAV
|
|
CN101495624A
(zh)
*
|
2006-04-28 |
2009-07-29 |
宾夕法尼亚州立大学托管会 |
衣壳免疫原性降低的经修饰aav载体及其用途
|
|
DK2548438T3
(en)
|
2006-11-08 |
2015-10-19 |
Veritas Bio LLC |
IN VIVO SUBMITTING DOUBLE-STRENGTH RNA TO A CELL
|
|
US8753662B2
(en)
|
2007-02-15 |
2014-06-17 |
National Jewish Health |
Methods and compositions for the disruption of biofilms
|
|
CA2680063A1
(en)
|
2007-02-23 |
2008-08-28 |
University Of Florida Research Foundation, Inc. |
Compositions and methods for treating glycogen storage diseases
|
|
HUE030719T2
(en)
|
2007-04-09 |
2017-05-29 |
Univ Florida |
Raav vector compositions having tyrosine-modified capsid proteins and methods for use
|
|
CA2683469C
(en)
|
2007-04-12 |
2019-11-26 |
The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth |
Genetic suppression and replacement
|
|
EP2152722B1
(en)
|
2007-05-03 |
2016-04-27 |
Merck Sharp & Dohme Corp. |
Compositions comprising mir34 therapeutic agents for treating cancer
|
|
EP2160477B1
(en)
|
2007-05-23 |
2013-08-07 |
Dharmacon, Inc. |
Micro-RNA scaffolds and non-naturally occurring micro-RNAs
|
|
CA2688061A1
(en)
|
2007-05-23 |
2008-12-04 |
Mannkind Corporation |
Multicistronic vectors and methods for their design
|
|
EP2012122A1
(en)
|
2007-07-06 |
2009-01-07 |
Medigene AG |
Mutated parvovirus structural proteins as vaccines
|
|
WO2008150897A2
(en)
|
2007-05-31 |
2008-12-11 |
University Of Iowa Research Foundation |
Reduction of off-target rna interference toxicity
|
|
PT3252161T
(pt)
|
2007-06-06 |
2022-02-01 |
Genzyme Corp |
Terapia genética para doenças do armazenamento lisossomal
|
|
EP2019143A1
(en)
|
2007-07-23 |
2009-01-28 |
Genethon |
CNS gene delivery using peripheral administration of AAV vectors
|
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
WO2009079592A2
(en)
|
2007-12-17 |
2009-06-25 |
California Institute Of Technology |
Modulating immune system development and function through microrna mir-146
|
|
US20090215879A1
(en)
|
2008-02-26 |
2009-08-27 |
University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
EP2268811A1
(en)
|
2008-03-07 |
2011-01-05 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microrna related diseases
|
|
WO2009146178A1
(en)
|
2008-04-15 |
2009-12-03 |
President And Fellows Of Harvard College |
Angiogenin and amyotrophic lateral sclerosis
|
|
DK2282764T3
(da)
|
2008-04-22 |
2019-10-14 |
Vib Vzw |
Leverspecifikke nukleinsyreregulerende elementer samt fremgangsmåder og anvendelser heraf
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
US8222221B2
(en)
|
2008-06-04 |
2012-07-17 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small RNA targeting of gene promoters
|
|
EP2297185A1
(en)
|
2008-06-17 |
2011-03-23 |
Amsterdam Molecular Therapeutics (AMT) B.V. |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
WO2010005850A1
(en)
|
2008-07-08 |
2010-01-14 |
The J. David Gladstone Institutes |
Methods and compositions for modulating angiogenesis
|
|
CA2744804C
(en)
|
2008-09-04 |
2019-02-05 |
Galenea Corp. |
Synaptic vesicle cycling assays and systems
|
|
WO2010034314A1
(en)
|
2008-09-24 |
2010-04-01 |
Aarhus Universitet |
Retroviral delivery of synthectic gene cassettes
|
|
WO2010071454A1
(en)
|
2008-12-17 |
2010-06-24 |
Auckland Uniservices Limited |
Adeno-associated viral vectors and uses thereof
|
|
WO2010071832A1
(en)
|
2008-12-19 |
2010-06-24 |
Nationwide Children's Hospital |
Delivery of polynucleotides across the blood brain barrier using recombinant aav9
|
|
WO2010099383A2
(en)
|
2009-02-26 |
2010-09-02 |
The Johns Hopkins University |
Compositions and methods for ex vivo hepatic nucleic acid delivery
|
|
JP5879256B2
(ja)
|
2009-05-02 |
2016-03-08 |
ジェンザイム・コーポレーション |
神経変性障害のための遺伝子治療
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
EP2261242A1
(en)
|
2009-06-10 |
2010-12-15 |
Universite Catholique De Louvain |
Aspartate-N-acetyltransferase enzyme, diagnostic method and therapeutic method
|
|
JP5847717B2
(ja)
|
2009-08-25 |
2016-01-27 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
脳に治療剤を送達するためのカニューレ配置の最適化
|
|
US20110076966A1
(en)
|
2009-09-28 |
2011-03-31 |
Sony Ericsson Mobile Communications Ab |
Method for driving an antenna of a mobile device
|
|
US20120270930A1
(en)
|
2009-10-29 |
2012-10-25 |
Academisch Ziekenhuis Leiden H.O.D.N. Lumc |
Methods and compositions for dysferlin exon-skipping
|
|
EP2498825B1
(en)
|
2009-11-09 |
2017-03-29 |
Genepod Therapeutics Ab |
Novel viral vector construct for neuron specific continuous dopa synthesis in vivo
|
|
EP2508603B1
(en)
|
2009-11-19 |
2015-05-13 |
National University Corporation Okayama University |
System for increasing gene expression, and vector supporting said system
|
|
ES2683695T3
(es)
|
2010-01-12 |
2018-09-27 |
The University Of North Carolina At Chapel Hill |
Repeticiones terminales invertidas restrictivas para vectores virales
|
|
ES2680915T3
(es)
|
2010-01-28 |
2018-09-11 |
The Children's Hospital Of Philadelphia |
Plataforma de fabricación escalable para la purificación de vectores virales y vectores virales purificados de este modo para su utilización en terapia génica
|
|
CA2791974A1
(en)
|
2010-03-01 |
2011-09-09 |
The Children's Hospital Of Philadelphia |
Nucleic acids for targeting multiple regions of the hcv genome
|
|
US9272053B2
(en)
|
2010-04-23 |
2016-03-01 |
University Of Massachusetts |
AAV-based treatment of cholesterol-related disorders
|
|
EP3567106A1
(en)
|
2010-04-23 |
2019-11-13 |
University of Massachusetts |
Cns targeting aav vectors and methods of use thereof
|
|
CA2833905C
(en)
|
2010-04-23 |
2019-09-10 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
US8785413B2
(en)
|
2010-09-27 |
2014-07-22 |
Florida Atlantic University Research Corporation |
Materials and methods for the treatment of pathological neovascularization in the eye
|
|
CN107828820B
(zh)
*
|
2010-10-27 |
2022-06-07 |
学校法人自治医科大学 |
用于向神经系统细胞导入基因的腺相关病毒粒子
|
|
WO2012109667A1
(en)
|
2011-02-12 |
2012-08-16 |
University Of Iowa Research Foundation |
Therapeutic compounds
|
|
SG10202007803QA
(en)
|
2011-02-17 |
2020-09-29 |
Univ Pennsylvania |
Compositions and methods for altering tissue specificity and improving aav9-mediated gene transfer
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
WO2012142434A2
(en)
|
2011-04-15 |
2012-10-18 |
THE UNITED STATES OF AMERICA, as represented by the secretary, Depart.of Healtth and Human Services |
Aav mediated ctla-4 gene transfer to treat sjogren's syndrome
|
|
US9226976B2
(en)
|
2011-04-21 |
2016-01-05 |
University Of Massachusetts |
RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
US8609088B2
(en)
|
2011-05-10 |
2013-12-17 |
Regents Of The University Of Minnesota |
Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
|
|
EP2766482B1
(en)
|
2011-10-11 |
2016-12-07 |
The Brigham and Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
CA2856137A1
(en)
*
|
2011-11-22 |
2013-05-30 |
The Children's Hospital Of Philadelphia |
Virus vectors for highly efficient transgene delivery
|
|
US20130142861A1
(en)
|
2011-12-05 |
2013-06-06 |
National Yang Ming University |
Compositions And Method For Detecting And Treating Abnormal Liver Homeostasis And Hepatocarcinogenesis
|
|
PT2814513T
(pt)
*
|
2012-02-14 |
2018-03-02 |
Univ California |
Entrega sistémica e expressão regulada de genes parácrinos para doenças cardiovasculares e outras doenças
|
|
KR102057540B1
(ko)
|
2012-02-17 |
2019-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
세포, 기관 및 조직으로의 유전자 전이를 위한 aav 벡터 조성물 및 방법
|
|
JP6342886B2
(ja)
|
2012-04-18 |
2018-06-13 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia |
Aavカプシドバリアントを使用した高効率な遺伝子導入のための組成物及び方法
|
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
JP6417322B2
(ja)
|
2012-06-21 |
2018-11-07 |
アソシアシオン・アンスティテュ・ドゥ・ミオロジーAssociation Institut De Myologie |
遺伝子治療ベクターの広範な遺伝子送達
|
|
IL239317B
(en)
|
2012-12-12 |
2022-07-01 |
Broad Inst Inc |
Providing, engineering and optimizing systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
CA2897932A1
(en)
|
2013-01-14 |
2014-07-17 |
Recombinetics, Inc. |
Hornless livestock
|
|
CA2905952A1
(en)
|
2013-03-13 |
2014-10-02 |
The Children's Hospital Of Philadelphia |
Adeno-associated virus vectors and methods of use thereof
|
|
AU2014227766B2
(en)
|
2013-03-15 |
2018-10-04 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for dual glycan binding AAV vectors
|
|
SG11201507875RA
(en)
|
2013-03-26 |
2015-10-29 |
Coherus Biosciences Inc |
Protein production method
|
|
EP2986635B1
(en)
|
2013-04-18 |
2018-10-03 |
Fondazione Telethon |
Effective delivery of large genes by dual aav vectors
|
|
US10006049B2
(en)
|
2013-05-16 |
2018-06-26 |
University Of Florida Research Foundation, Incorporated |
Hairpin mRNA elements and methods for the regulation of protein translation
|
|
ES3029138T3
(en)
|
2013-06-05 |
2025-06-23 |
Univ Duke |
Rna-guided gene editing and gene regulation
|
|
MX2015017312A
(es)
|
2013-06-17 |
2017-04-10 |
Broad Inst Inc |
Suministro y uso de composiciones, vectores y sistemas crispr-cas para la modificación dirigida y terapia hepáticas.
|
|
WO2015009575A1
(en)
|
2013-07-16 |
2015-01-22 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of disorders related to cep290
|
|
EP3030665B9
(en)
|
2013-08-05 |
2023-10-04 |
Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum |
Recombinant aav-crumbs homologue composition and methods for treating lca-8 and progressive rp
|
|
RS63942B1
(sr)
|
2013-08-27 |
2023-02-28 |
Res Inst Nationwide Childrens Hospital |
Proizvodi i postupci za lečenje amiotrofične lateralne skleroze
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
US10072251B2
(en)
|
2014-02-19 |
2018-09-11 |
University Of Massachusetts |
Recombinant AAVS having useful transcytosis properties
|
|
WO2015150922A2
(en)
|
2014-03-17 |
2015-10-08 |
The Hospital For Sick Children |
β-HEXOSAMINIDASE PROTEIN VARIANTS AND ASSOCIATED METHODS FOR TREATING GM2 GANGLIOSIDOSES
|
|
CA3276269A1
(en)
|
2014-03-18 |
2026-03-02 |
University Of Massachusetts |
Raav-based compositions and methods for treating amyotrophic lateral sclerosis
|
|
US10975391B2
(en)
|
2014-04-25 |
2021-04-13 |
University Of Massachusetts |
Recombinant AAV vectors useful for reducing immunity against transgene products
|
|
EP3137497B2
(en)
|
2014-05-02 |
2025-03-05 |
Genzyme Corporation |
Aav vectors for retinal and cns gene therapy
|
|
ES2759317T3
(es)
|
2014-05-20 |
2020-05-08 |
Univ Iowa Res Found |
Compuestos terapéuticos para la enfermedad de Huntington
|
|
WO2015187825A2
(en)
|
2014-06-03 |
2015-12-10 |
University Of Massachusetts |
Compositions and methods for modulating dysferlin expression
|
|
RU2020140209A
(ru)
*
|
2014-10-21 |
2021-01-25 |
Юниверсити Оф Массачусетс |
Варианты рекомбинантных aav и их применения
|
|
US20190000940A1
(en)
|
2015-07-31 |
2019-01-03 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
US20200316221A1
(en)
|
2016-10-13 |
2020-10-08 |
University Of Massachusetts |
Aav capsid designs
|
|
CA3040483A1
(en)
|
2016-10-13 |
2018-04-19 |
University Of Massachusetts |
Aav capsid designs
|