|
US530579A
(en)
|
|
1894-12-11 |
|
Side bearing for cars |
|
US5043270A
(en)
|
1989-03-31 |
1991-08-27 |
The Board Of Trustees Of The Leland Stanford Junior University |
Intronic overexpression vectors
|
|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5399363A
(en)
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
JPH10501686A
(ja)
|
1994-04-13 |
1998-02-17 |
ザ ロックフェラー ユニヴァーシティ |
神経系の細胞へのｄｎａのａａｖ仲介送達
|
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
|
IE80468B1
(en)
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
|
US6391607B1
(en)
|
1996-06-14 |
2002-05-21 |
Genentech, Inc. |
Human DNase I hyperactive variants
|
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
|
US6083716A
(en)
|
1996-09-06 |
2000-07-04 |
The Trustees Of The University Of Pennsylvania |
Chimpanzee adenovirus vectors
|
|
US6177403B1
(en)
|
1996-10-21 |
2001-01-23 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US6475469B1
(en)
|
1996-11-21 |
2002-11-05 |
Applied Dental Sciences, Inc. |
Compositions for removing tooth stains
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
JP2001517454A
(ja)
|
1997-09-19 |
2001-10-09 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスの産生に有用な方法および細胞株
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
CA2329259C
(en)
|
1998-05-27 |
2003-08-05 |
Avigen, Inc. |
Convection-enhanced delivery of aav vectors
|
|
DE69939169D1
(de)
|
1998-05-28 |
2008-09-04 |
Us Gov Health & Human Serv |
Aav5 vektoren und deren verwendung
|
|
EP1097244A4
(en)
|
1998-07-22 |
2002-08-07 |
Immusol Inc |
SUBSTANTIALLY COMPLETE RIBOZYME BANKS
|
|
US20030110526A1
(en)
|
1998-08-25 |
2003-06-12 |
Robert H. Brown |
Dysferlin mutations
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
US6365394B1
(en)
|
1999-09-29 |
2002-04-02 |
The Trustees Of The University Of Pennsylvania |
Cell lines and constructs useful in production of E1-deleted adenoviruses in absence of replication competent adenovirus
|
|
US6544786B1
(en)
|
1999-10-15 |
2003-04-08 |
University Of Pittsburgh Of The Commonwealth Of Higher Education |
Method and vector for producing and transferring trans-spliced peptides
|
|
US6821512B1
(en)
|
1999-12-03 |
2004-11-23 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for increasing packaging and yield of recombinant adenoviruses using multiple packaging signals
|
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
US20040136963A1
(en)
|
2001-06-22 |
2004-07-15 |
The Trustees Of The University Of Pennsylvania |
Simian adenovirus vectors and methods of use
|
|
US7344872B2
(en)
|
2001-06-22 |
2008-03-18 |
The Trustees Of The University Of Pennsylvania |
Method for rapid screening of bacterial transformants and novel simian adenovirus proteins
|
|
EP1402043A1
(en)
|
2001-07-03 |
2004-03-31 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of administering vectors to synaptically connected neurons
|
|
CA2453405A1
(en)
|
2001-07-13 |
2003-01-23 |
University Of Iowa Research Foundation |
Pseudotyped adeno-associated viruses and uses thereof
|
|
US20030050273A1
(en)
|
2001-08-29 |
2003-03-13 |
Keiya Ozawa |
Compositions and methods for treating neurodegenerative diseases
|
|
US20030092161A1
(en)
|
2001-09-19 |
2003-05-15 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for production of recombinant viruses, and uses therefor
|
|
CN103589692B
(zh)
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
MXPA04004876A
(es)
|
2001-11-21 |
2004-07-30 |
Univ Pennsylvania |
Secuencias de acido nucleico y de aminoacido de adenovirus de simio, vectores que contienen los mismos y metodos de uso.
|
|
EP1463805B1
(en)
|
2001-12-17 |
2014-10-22 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
US20050137153A1
(en)
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
|
AU2003221733A1
(en)
|
2002-04-17 |
2003-11-03 |
University Of Florida Research Foundation, Inc. |
Improved raav vectors
|
|
WO2003089011A1
(en)
|
2002-04-19 |
2003-10-30 |
University Of Florida |
rAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES
|
|
US7235393B2
(en)
|
2002-04-29 |
2007-06-26 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular DNA of tissues
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20050255086A1
(en)
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
US20050143330A1
(en)
|
2002-09-30 |
2005-06-30 |
Ron Mandel |
Method for the treatment of Parkinson's Disease
|
|
US20060206949A1
(en)
|
2003-01-28 |
2006-09-14 |
Sylvain Arnould |
Custom-made meganuclease and use thereof
|
|
US7387896B2
(en)
|
2003-03-26 |
2008-06-17 |
The Regents Of The University Of Michigan |
MicroRNA vectors
|
|
WO2004108922A2
(en)
|
2003-04-25 |
2004-12-16 |
The Trustees Of The University Of Pennsylvania |
Use of aav comprising a capsid protein from aav7 or aav8 for the delivery of genes encoding apoprotein a or e genes to the liver
|
|
US20060228800A1
(en)
|
2003-05-15 |
2006-10-12 |
Shi-Lung Lin |
Novel Transgenic Methods Using intronic RNA
|
|
CA2528012C
(en)
|
2003-06-02 |
2015-11-24 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of rna silencing
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
ATE508190T1
(de)
|
2004-03-05 |
2011-05-15 |
Benitec Inc |
Mehrfachpromotor-expressionskassetten zurgleichzeitigen zuführung von rnai-agentien
|
|
WO2005096781A2
(en)
|
2004-04-06 |
2005-10-20 |
University Of Massachusetts |
Methods and compositions for treating gain-of-function disorders using rna interference
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
US20060073119A1
(en)
|
2004-09-01 |
2006-04-06 |
Avigen, Inc. |
Methods for treating neurodegenerative disorders
|
|
US20060189564A1
(en)
|
2004-10-22 |
2006-08-24 |
Medtronic, Inc. |
Methods and sequences to suppress pro-inflamatory cytokine actions locally to treat pain
|
|
WO2006063247A2
(en)
|
2004-12-09 |
2006-06-15 |
Genzyme Corporation |
Regulated expression of transgenes in the central nervous system of mammals
|
|
EP1828390B1
(en)
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
US7803611B2
(en)
|
2005-02-03 |
2010-09-28 |
Benitec, Inc. |
RNAi expression constructs
|
|
DE23193606T1
(de)
*
|
2005-04-07 |
2024-02-15 |
The Trustees Of The University Of Pennsylvania |
Verfahren zur erhöhung der funktion eines aav-vektors
|
|
AU2006242371A1
(en)
|
2005-04-29 |
2006-11-09 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for regulated expression of nucleic acid at post-transcriptional level
|
|
US20060247655A1
(en)
|
2005-05-02 |
2006-11-02 |
Sdgi Holdings, Inc. |
Instrument to insert a prosthetic implant
|
|
DK2002003T3
(en)
|
2005-05-27 |
2016-03-21 |
Ospedale San Raffaele Srl |
Gene vector comprising miRNA
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
ATE494372T1
(de)
|
2005-08-29 |
2011-01-15 |
Regulus Therapeutics Inc |
Verfahren für mir-122a-modulation
|
|
EP2484782B1
(en)
|
2006-01-05 |
2015-11-18 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
WO2008016391A2
(en)
|
2006-01-31 |
2008-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
SI1986661T1
(sl)
|
2006-02-08 |
2018-12-31 |
Genzyme Corporation |
Genska terapija za Niemann-Pickovo bolezen tipa A
|
|
EP2514824A3
(en)
|
2006-03-03 |
2013-01-23 |
Amorfix Life Sciences Ltd. |
Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
CN101528916B
(zh)
|
2006-04-28 |
2013-09-04 |
宾夕法尼亚大学托管会 |
规模可调的aav生产方法
|
|
JP2009535339A
(ja)
|
2006-04-28 |
2009-10-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
低下されたキャプシド免疫原性を有する改変ａａｖベクターおよびその使用
|
|
DK2094086T3
(da)
|
2006-11-08 |
2013-11-25 |
Veritas Bio LLC |
Indgivelse in vivo af dobbeltstrenget rna til en målcelle
|
|
EP2114460B1
(en)
|
2007-02-15 |
2014-07-16 |
National Jewish Health |
Compositions for the disruption of biofilms
|
|
WO2008103993A2
(en)
|
2007-02-23 |
2008-08-28 |
University Of Florida Research Foundation, Inc. |
Compositions and methods for treating glycogen storage diseases
|
|
DK2623605T3
(en)
|
2007-04-09 |
2019-03-25 |
Univ Florida |
RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
|
|
US8257969B2
(en)
|
2007-04-12 |
2012-09-04 |
The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth |
Genetic suppression and replacement
|
|
US8399248B2
(en)
|
2007-05-03 |
2013-03-19 |
Merck Sharp & Dohme Corp. |
Methods of using MIR34 as a biomarker for TP53 functional status
|
|
WO2008147839A1
(en)
|
2007-05-23 |
2008-12-04 |
Dharmacon, Inc. |
Micro-rna scaffolds and non-naturally occurring micro-rnas
|
|
EP2152890A1
(en)
|
2007-05-23 |
2010-02-17 |
MannKind Corporation |
Multicistronic vectors and methods for their design
|
|
EP2012122A1
(en)
|
2007-07-06 |
2009-01-07 |
Medigene AG |
Mutated parvovirus structural proteins as vaccines
|
|
DK2164967T3
(en)
|
2007-05-31 |
2015-10-19 |
Univ Iowa Res Found |
Reduction of off-target rna interferenstoksicitet
|
|
PL2158322T3
(pl)
|
2007-06-06 |
2017-10-31 |
Genzyme Corp |
Terapia genowa dla lizosomalnych chorób spichrzeniowych
|
|
EP2019143A1
(en)
|
2007-07-23 |
2009-01-28 |
Genethon |
CNS gene delivery using peripheral administration of AAV vectors
|
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
US9090894B2
(en)
|
2007-12-17 |
2015-07-28 |
California Institute Of Technology |
Modulating immune system development and function through microRNA MIR-146
|
|
WO2009108274A2
(en)
|
2008-02-26 |
2009-09-03 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
EP2268811A1
(en)
|
2008-03-07 |
2011-01-05 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microrna related diseases
|
|
WO2009146178A1
(en)
|
2008-04-15 |
2009-12-03 |
President And Fellows Of Harvard College |
Angiogenin and amyotrophic lateral sclerosis
|
|
US9617548B2
(en)
|
2008-04-22 |
2017-04-11 |
Vib Vzw |
Liver-specific nucleic acid regulatory elements and methods and use thereof
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
CA2726052A1
(en)
|
2008-06-04 |
2009-12-10 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small rna targeting of gene promoters
|
|
US20110171262A1
(en)
|
2008-06-17 |
2011-07-14 |
Andrew Christian Bakker |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
EP2310507A4
(en)
|
2008-07-08 |
2013-03-20 |
David Gladstone Inst |
METHOD AND COMPOSITIONS FOR ANGIOGENIC MODULATION
|
|
CN102203622A
(zh)
|
2008-09-04 |
2011-09-28 |
加利尼公司 |
突触小泡循环的测定和系统
|
|
WO2010034314A1
(en)
|
2008-09-24 |
2010-04-01 |
Aarhus Universitet |
Retroviral delivery of synthectic gene cassettes
|
|
WO2010071454A1
(en)
|
2008-12-17 |
2010-06-24 |
Auckland Uniservices Limited |
Adeno-associated viral vectors and uses thereof
|
|
WO2010071832A1
(en)
|
2008-12-19 |
2010-06-24 |
Nationwide Children's Hospital |
Delivery of polynucleotides across the blood brain barrier using recombinant aav9
|
|
WO2010099383A2
(en)
|
2009-02-26 |
2010-09-02 |
The Johns Hopkins University |
Compositions and methods for ex vivo hepatic nucleic acid delivery
|
|
SI3988660T1
(sl)
|
2009-05-02 |
2025-09-30 |
Genzyme Corporation |
Genska terapija za nevrodegenerativne motnje
|
|
US8734809B2
(en)
*
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
EP2261242A1
(en)
|
2009-06-10 |
2010-12-15 |
Universite Catholique De Louvain |
Aspartate-N-acetyltransferase enzyme, diagnostic method and therapeutic method
|
|
KR101649145B1
(ko)
|
2009-08-25 |
2016-08-18 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
뇌에 치료제를 송달하기 위한 캐뉼라의 최적화된 배치
|
|
US20110076966A1
(en)
|
2009-09-28 |
2011-03-31 |
Sony Ericsson Mobile Communications Ab |
Method for driving an antenna of a mobile device
|
|
US20120270930A1
(en)
|
2009-10-29 |
2012-10-25 |
Academisch Ziekenhuis Leiden H.O.D.N. Lumc |
Methods and compositions for dysferlin exon-skipping
|
|
AU2010316982B2
(en)
|
2009-11-09 |
2013-09-12 |
Genepod Therapeutics Ab |
Novel viral vector construct for neuron specific continuous DOPA synthesis in vivo
|
|
WO2011062298A1
(ja)
|
2009-11-19 |
2011-05-26 |
国立大学法人岡山大学 |
遺伝子発現を上昇させるシステム及び該システムを保持したベクター
|
|
US9169494B2
(en)
|
2010-01-12 |
2015-10-27 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
|
EP2529020B1
(en)
|
2010-01-28 |
2018-04-25 |
The Children's Hospital of Philadelphia |
A scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
|
|
WO2011109380A1
(en)
|
2010-03-01 |
2011-09-09 |
The Children's Hospital Of Philadelphia |
Nucleic acids for targeting multiple regions of the hcv genome
|
|
CA3050894C
(en)
|
2010-04-23 |
2022-10-18 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
CA2833912C
(en)
|
2010-04-23 |
2021-09-21 |
University Of Massachusetts |
Aav-based treatment of cholesterol-related disorders
|
|
DK2561073T3
(en)
|
2010-04-23 |
2016-12-12 |
Univ Massachusetts |
Aav vectors targeted to central nervous system and methods of use thereof
|
|
US8785413B2
(en)
|
2010-09-27 |
2014-07-22 |
Florida Atlantic University Research Corporation |
Materials and methods for the treatment of pathological neovascularization in the eye
|
|
US10738326B2
(en)
|
2010-10-27 |
2020-08-11 |
Jichi Medical University |
Adeno-associated virus vector for gene transfer to nervous system cells
|
|
ES2739804T3
(es)
|
2011-02-12 |
2020-02-04 |
Univ Iowa Res Found |
Compuestos terapéuticos
|
|
CN103502458B
(zh)
|
2011-02-17 |
2016-11-16 |
宾夕法尼亚大学托管会 |
用于改变组织特异性和改善aav9-介导的基因转移的组合物和方法
|
|
US20140201857A1
(en)
|
2013-01-14 |
2014-07-17 |
Recombinetics, Inc. |
Hornless livestock
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
EP2699258A4
(en)
|
2011-04-15 |
2014-10-29 |
Us Sec Dep Of Health And Human Services |
AAV-mediated CTLA-4 gene transfer for the treatment of SJÖGREN SYNDROME
|
|
WO2012145624A2
(en)
|
2011-04-21 |
2012-10-26 |
University Of Massachusetts |
Raav-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
US8609088B2
(en)
|
2011-05-10 |
2013-12-17 |
Regents Of The University Of Minnesota |
Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
|
|
EP2766482B1
(en)
|
2011-10-11 |
2016-12-07 |
The Brigham and Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
EP2782596A4
(en)
|
2011-11-22 |
2015-07-29 |
Philadelphia Children Hospital |
VIRUS VECTORS FOR HIGHLY EFFICIENT TRANSGENIC ADMINISTRATION
|
|
US20130142861A1
(en)
|
2011-12-05 |
2013-06-06 |
National Yang Ming University |
Compositions And Method For Detecting And Treating Abnormal Liver Homeostasis And Hepatocarcinogenesis
|
|
JP6562632B2
(ja)
|
2012-02-14 |
2019-08-21 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
心血管疾患および他の状態のためのパラクリン遺伝子の全身送達および制御された発現
|
|
BR112014020325A2
(pt)
|
2012-02-17 |
2017-08-08 |
Childrens Hospital Philadelphia |
composições de vetor do aav e métodos para a transferência de gene para as células, órgãos e tecidos
|
|
JP6342886B2
(ja)
|
2012-04-18 |
2018-06-13 |
ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ |
Ａａｖカプシドバリアントを使用した高効率な遺伝子導入のための組成物及び方法
|
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
CN104704123A
(zh)
|
2012-06-21 |
2015-06-10 |
肌肉学研究协会 |
基因治疗载体的广泛的基因递送
|
|
SG10201707569YA
(en)
|
2012-12-12 |
2017-10-30 |
Broad Inst Inc |
Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
ES2926774T3
(es)
|
2013-03-15 |
2022-10-28 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para vectores AAV de doble unión de glicano
|
|
SG10201802023RA
(en)
|
2013-03-26 |
2018-05-30 |
Coherus Biosciences Inc |
Protein production method
|
|
DK2986635T3
(en)
|
2013-04-18 |
2019-01-28 |
Fond Telethon |
EFFECTIVE DELIVERY OF BIG GENES THROUGH DUAL-AAV VECTORS
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
WO2014197748A2
(en)
|
2013-06-05 |
2014-12-11 |
Duke University |
Rna-guided gene editing and gene regulation
|
|
JP6738728B2
(ja)
|
2013-06-17 |
2020-08-19 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
肝臓ターゲティングおよび治療のためのＣＲＩＳＰＲ−Ｃａｓ系、ベクターおよび組成物の送達および使用
|
|
US10155794B2
(en)
|
2013-07-16 |
2018-12-18 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of disorders related to CEP290
|
|
CN105980569A
(zh)
|
2013-08-05 |
2016-09-28 |
莱顿大学医学中心附属莱顿教学医院 |
重组aav-crumbs同源物组合物及治疗lca-8和进行性rp的方法
|
|
RS63942B1
(sr)
|
2013-08-27 |
2023-02-28 |
Res Inst Nationwide Childrens Hospital |
Proizvodi i postupci za lečenje amiotrofične lateralne skleroze
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
*
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
|
EP3119892B1
(en)
|
2014-03-17 |
2021-03-10 |
The Hospital For Sick Children |
Beta-hexosaminidase protein variants and associated methods for treating gm2 gangliosdoses
|
|
JP6756700B2
(ja)
|
2014-03-18 |
2020-09-16 |
ユニバーシティ オブ マサチューセッツ |
筋萎縮性側索硬化症を処置するためのｒＡＡＶベースの組成物および方法
|
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
|
LT3137497T
(lt)
|
2014-05-02 |
2021-07-26 |
Genzyme Corporation |
Aav vektoriai, skirti tinklainės ir cns genų terapijai
|
|
AU2015264263B2
(en)
|
2014-05-20 |
2021-08-05 |
University Of Iowa Research Foundation |
Huntington's disease therapeutic compounds
|
|
US10689653B2
(en)
|
2014-06-03 |
2020-06-23 |
University Of Massachusetts |
Compositions and methods for modulating dysferlin expression
|
|
WO2016065001A1
(en)
|
2014-10-21 |
2016-04-28 |
University Of Massachusetts |
Recombinant aav variants and uses thereof
|
|
WO2017023724A1
(en)
|
2015-07-31 |
2017-02-09 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
KR20190075964A
(ko)
|
2016-10-13 |
2019-07-01 |
유니버시티 오브 매사추세츠 |
Aav 캡시드 설계
|
|
US20200316221A1
(en)
|
2016-10-13 |
2020-10-08 |
University Of Massachusetts |
Aav capsid designs
|