JP2013515474A5 - - Google Patents

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Publication number
JP2013515474A5
JP2013515474A5 JP2012545436A JP2012545436A JP2013515474A5 JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5 JP 2012545436 A JP2012545436 A JP 2012545436A JP 2012545436 A JP2012545436 A JP 2012545436A JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5
Authority
JP
Japan
Prior art keywords
factor
variant
nucleic acid
acid sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2012545436A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013515474A (ja
Filing date
Publication date
Priority claimed from GBGB0922659.8A external-priority patent/GB0922659D0/en
Application filed filed Critical
Publication of JP2013515474A publication Critical patent/JP2013515474A/ja
Publication of JP2013515474A5 publication Critical patent/JP2013515474A5/ja
Abandoned legal-status Critical Current

Links

JP2012545436A 2009-12-24 2010-12-23 組換え体h因子ならびにそのバリアントおよびコンジュゲート Abandoned JP2013515474A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0922659.8 2009-12-24
GBGB0922659.8A GB0922659D0 (en) 2009-12-24 2009-12-24 Factor H
PCT/GB2010/002334 WO2011077102A1 (en) 2009-12-24 2010-12-23 Recombinant factor h and variants and conjugates thereof

Publications (2)

Publication Number Publication Date
JP2013515474A JP2013515474A (ja) 2013-05-09
JP2013515474A5 true JP2013515474A5 (enExample) 2014-02-20

Family

ID=41716988

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012545436A Abandoned JP2013515474A (ja) 2009-12-24 2010-12-23 組換え体h因子ならびにそのバリアントおよびコンジュゲート

Country Status (5)

Country Link
US (3) US8889374B2 (enExample)
EP (1) EP2516464B1 (enExample)
JP (1) JP2013515474A (enExample)
GB (1) GB0922659D0 (enExample)
WO (1) WO2011077102A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0922659D0 (en) 2009-12-24 2010-02-10 Univ Edinburgh Factor H
FR2981661B1 (fr) * 2011-10-25 2015-06-19 Lfb Biotechnologies Procede de preparation du facteur h humain
FR3015484A1 (fr) * 2013-12-20 2015-06-26 Lab Francais Du Fractionnement Proteines recombinantes possedant une activite de facteur h
FR3038517B1 (fr) 2015-07-06 2020-02-28 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Utilisation de fragments fc modifies en immunotherapie
EP3359663A4 (en) * 2015-09-24 2019-08-14 The Trustees of The University of Pennsylvania COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE
WO2017075189A1 (en) * 2015-10-27 2017-05-04 University Of Massachusetts Factor h-fc immunotherapy
GB201706808D0 (en) 2017-04-28 2017-06-14 Univ Newcastle Modified complement proteins and uses thereof
GB201800620D0 (en) 2018-01-15 2018-02-28 Univ Manchester C3b Binding Polypeptide
US20210338838A1 (en) * 2018-07-20 2021-11-04 University Of Utah Research Foundation Gene therapy for macular degeneration
WO2020056122A1 (en) * 2018-09-13 2020-03-19 Regeneron Pharmaceuticals, Inc. Complement factor h gene knockout rat as a model of c3 glomerulopathy
IL299048A (en) 2020-06-14 2023-02-01 Vertex Pharma Variants of complement factor - 1 fusion structures and preparations containing them and their uses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7037504B2 (en) 2001-10-23 2006-05-02 Waratah Pharmaceuticals, Inc. Epidermal growth factor protein and gene, and methods of use therefor
EP1336618A1 (en) 2002-02-15 2003-08-20 HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. Porcine complement regulator factor H and its use
US8088579B2 (en) 2005-02-14 2012-01-03 University Of Iowa Research Foundation Complement factor H for diagnosis of age-related macular degeneration
JP2009508822A (ja) 2005-09-19 2009-03-05 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー 慢性腎症の処置のためのh因子およびその製造
PT2044111E (pt) * 2006-06-21 2014-11-12 Univ Colorado Regents Abordagem seletiva do fator h do complemento para o tratamento de doenças
JP2010526528A (ja) 2007-05-03 2010-08-05 メディツィニーチェ ウニベルシタット インスブルック 補体因子h由来ショートコンセンサスリピート−抗体構築物
WO2008139496A1 (en) 2007-05-16 2008-11-20 Bigtec Private Limited Recombinant human insulin and a method thereof
GB0922659D0 (en) 2009-12-24 2010-02-10 Univ Edinburgh Factor H
US20130011857A1 (en) 2010-02-12 2013-01-10 Cemm Forschungszentrum Fur Molekulare Medizin Gmbh Complement factor h for oxidative stress disease conditions
WO2013142362A1 (en) 2012-03-19 2013-09-26 The Trustees Of The University Of Pennsylvania Regulator of complement activation and uses thereof

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