JP2013515474A5 - - Google Patents
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- Publication number
- JP2013515474A5 JP2013515474A5 JP2012545436A JP2012545436A JP2013515474A5 JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5 JP 2012545436 A JP2012545436 A JP 2012545436A JP 2012545436 A JP2012545436 A JP 2012545436A JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5
- Authority
- JP
- Japan
- Prior art keywords
- factor
- variant
- nucleic acid
- acid sequence
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0922659.8 | 2009-12-24 | ||
| GBGB0922659.8A GB0922659D0 (en) | 2009-12-24 | 2009-12-24 | Factor H |
| PCT/GB2010/002334 WO2011077102A1 (en) | 2009-12-24 | 2010-12-23 | Recombinant factor h and variants and conjugates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515474A JP2013515474A (ja) | 2013-05-09 |
| JP2013515474A5 true JP2013515474A5 (enExample) | 2014-02-20 |
Family
ID=41716988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545436A Abandoned JP2013515474A (ja) | 2009-12-24 | 2010-12-23 | 組換え体h因子ならびにそのバリアントおよびコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8889374B2 (enExample) |
| EP (1) | EP2516464B1 (enExample) |
| JP (1) | JP2013515474A (enExample) |
| GB (1) | GB0922659D0 (enExample) |
| WO (1) | WO2011077102A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| FR2981661B1 (fr) * | 2011-10-25 | 2015-06-19 | Lfb Biotechnologies | Procede de preparation du facteur h humain |
| FR3015484A1 (fr) * | 2013-12-20 | 2015-06-26 | Lab Francais Du Fractionnement | Proteines recombinantes possedant une activite de facteur h |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| EP3359663A4 (en) * | 2015-09-24 | 2019-08-14 | The Trustees of The University of Pennsylvania | COMPOSITION AND METHOD FOR THE TREATMENT OF A COMPLEMENT-MEDIATED DISEASE |
| WO2017075189A1 (en) * | 2015-10-27 | 2017-05-04 | University Of Massachusetts | Factor h-fc immunotherapy |
| GB201706808D0 (en) | 2017-04-28 | 2017-06-14 | Univ Newcastle | Modified complement proteins and uses thereof |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| US20210338838A1 (en) * | 2018-07-20 | 2021-11-04 | University Of Utah Research Foundation | Gene therapy for macular degeneration |
| WO2020056122A1 (en) * | 2018-09-13 | 2020-03-19 | Regeneron Pharmaceuticals, Inc. | Complement factor h gene knockout rat as a model of c3 glomerulopathy |
| IL299048A (en) | 2020-06-14 | 2023-02-01 | Vertex Pharma | Variants of complement factor - 1 fusion structures and preparations containing them and their uses |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037504B2 (en) | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
| EP1336618A1 (en) | 2002-02-15 | 2003-08-20 | HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. | Porcine complement regulator factor H and its use |
| US8088579B2 (en) | 2005-02-14 | 2012-01-03 | University Of Iowa Research Foundation | Complement factor H for diagnosis of age-related macular degeneration |
| JP2009508822A (ja) | 2005-09-19 | 2009-03-05 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | 慢性腎症の処置のためのh因子およびその製造 |
| PT2044111E (pt) * | 2006-06-21 | 2014-11-12 | Univ Colorado Regents | Abordagem seletiva do fator h do complemento para o tratamento de doenças |
| JP2010526528A (ja) | 2007-05-03 | 2010-08-05 | メディツィニーチェ ウニベルシタット インスブルック | 補体因子h由来ショートコンセンサスリピート−抗体構築物 |
| WO2008139496A1 (en) | 2007-05-16 | 2008-11-20 | Bigtec Private Limited | Recombinant human insulin and a method thereof |
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| US20130011857A1 (en) | 2010-02-12 | 2013-01-10 | Cemm Forschungszentrum Fur Molekulare Medizin Gmbh | Complement factor h for oxidative stress disease conditions |
| WO2013142362A1 (en) | 2012-03-19 | 2013-09-26 | The Trustees Of The University Of Pennsylvania | Regulator of complement activation and uses thereof |
-
2009
- 2009-12-24 GB GBGB0922659.8A patent/GB0922659D0/en not_active Ceased
-
2010
- 2010-12-23 JP JP2012545436A patent/JP2013515474A/ja not_active Abandoned
- 2010-12-23 US US13/518,614 patent/US8889374B2/en active Active
- 2010-12-23 WO PCT/GB2010/002334 patent/WO2011077102A1/en not_active Ceased
- 2010-12-23 EP EP10803266.5A patent/EP2516464B1/en not_active Not-in-force
-
2014
- 2014-11-14 US US14/541,834 patent/US20150139975A1/en not_active Abandoned
-
2017
- 2017-04-10 US US15/483,814 patent/US10378005B2/en not_active Expired - Fee Related
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