JP2009520758A5 - - Google Patents
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- Publication number
- JP2009520758A5 JP2009520758A5 JP2008546433A JP2008546433A JP2009520758A5 JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5 JP 2008546433 A JP2008546433 A JP 2008546433A JP 2008546433 A JP2008546433 A JP 2008546433A JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- binding domain
- polypeptide
- igg binding
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002163 immunogen Effects 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 210000002925 A-like Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005847 immunogenicity Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0526038A GB0526038D0 (en) | 2005-12-21 | 2005-12-21 | Immunogenic composition |
| GB0526038.5 | 2005-12-21 | ||
| PCT/EP2006/069944 WO2007071692A2 (en) | 2005-12-21 | 2006-12-19 | Immunogenic composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Division JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520758A JP2009520758A (ja) | 2009-05-28 |
| JP2009520758A5 true JP2009520758A5 (enExample) | 2010-02-12 |
| JP5780693B2 JP5780693B2 (ja) | 2015-09-16 |
Family
ID=35840898
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546433A Expired - Fee Related JP5780693B2 (ja) | 2005-12-21 | 2006-12-19 | 免疫原性組成物 |
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080311146A1 (enExample) |
| EP (1) | EP1962890B1 (enExample) |
| JP (2) | JP5780693B2 (enExample) |
| CA (1) | CA2634898A1 (enExample) |
| ES (1) | ES2558703T3 (enExample) |
| GB (1) | GB0526038D0 (enExample) |
| WO (1) | WO2007071692A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0610776D0 (en) * | 2006-05-31 | 2006-07-12 | Univ Bath | Novel applications for staphylococcus aureus Sbi protein |
| US7691608B2 (en) | 2006-12-06 | 2010-04-06 | Repligen Corporation | Nucleic acids encoding recombinant protein A |
| HRP20160274T1 (hr) | 2009-04-03 | 2016-04-08 | University Of Chicago | Pripravci i metode vezane za varijante proteina a (spa) |
| EP2419129A2 (en) | 2009-04-14 | 2012-02-22 | Novartis AG | Compositions for immunising against staphylococcus aerus |
| US8974799B2 (en) | 2009-09-30 | 2015-03-10 | Novartis Ag | Conjugation of Staphylococcus aureus type 5 and type 8 capsular polysaccharides |
| PT2493498T (pt) | 2009-10-30 | 2017-05-24 | Glaxosmithkline Biologicals Sa | Purificação de sacáridos capsulares de staphylococcus aureus tipo 5 e tipo 8 |
| AU2011274367B2 (en) | 2010-07-02 | 2015-04-23 | The University Of Chicago | Compositions and methods related to protein A (SpA) variants |
| JP5793194B2 (ja) * | 2010-09-09 | 2015-10-14 | ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ | 感染防御ブドウ球菌抗原が関与する方法および組成物 |
| WO2013096948A1 (en) * | 2011-12-23 | 2013-06-27 | Lydon Nicholas B | Immunoglobulins and variants directed against pathogenic microbes |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| CN102698260B (zh) * | 2012-04-20 | 2013-09-25 | 西北农林科技大学 | 预防山羊葡萄球菌乳房炎的亚单位疫苗的制备方法及应用 |
| WO2015073801A1 (en) * | 2013-11-14 | 2015-05-21 | Duke University | Tetanus toxoid and ccl3 improve dc vaccines |
| CN106163550A (zh) * | 2013-12-04 | 2016-11-23 | 格林考瓦因有限公司 | 通过大肠杆菌中合成的糖蛋白疫苗预防金黄色葡萄球菌感染 |
| CN103694322B (zh) * | 2013-12-09 | 2016-08-17 | 成都欧林生物科技股份有限公司 | 金黄色葡萄球菌SpA5突变体及其制备方法和应用 |
| MX377794B (es) | 2014-03-26 | 2025-03-10 | Glaxosmithkline Biologicals Sa | Antigenos estafilococicos mutantes. |
| GB201619965D0 (en) * | 2016-11-25 | 2017-01-11 | Univ Of Bath The | Immunogenic compositions comprising sbi protein and uses thereof |
| GB201802339D0 (en) | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| CA3139981A1 (en) | 2019-05-14 | 2020-11-19 | The University Of Chicago | Methods and compositions comprising staphylococcus protein a (spa) variants |
| EP3777884A1 (en) * | 2019-08-15 | 2021-02-17 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| CN115702002A (zh) * | 2020-04-23 | 2023-02-14 | 朝途生物疗法株式会社 | 改良肽疫苗 |
| WO2024129976A2 (en) * | 2022-12-14 | 2024-06-20 | Scribe Therapeutics Inc. | Particle delivery systems |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571514A (en) * | 1987-06-01 | 1996-11-05 | Alfa Laval Ab | Fibronectin binding protein as well as its preparation |
| SE9704141D0 (sv) * | 1997-11-12 | 1997-11-12 | Sbl Vaccin Ab | New protein and nucleotide sequence, encoding said protein |
| WO2000012132A1 (en) | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| IL141639A (en) | 1998-08-31 | 2005-12-18 | Inhibitex Inc | Multicomponent vaccines |
| ES2321892T3 (es) | 1998-09-14 | 2009-06-12 | Nabi Biopharmaceuticals | Composiciones de beta-glucanos e inmunoglobulinas especificas. |
| US7098383B2 (en) * | 2000-12-19 | 2006-08-29 | Sembiosys Genetics Inc. | Methods for the production of multimeric immunoglobulins, and related compositions |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| NZ561879A (en) * | 2003-03-07 | 2009-05-31 | Wyeth Corp | Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| US20050137220A1 (en) * | 2003-07-23 | 2005-06-23 | Pharmacia Corporation | Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors |
| NZ544542A (en) * | 2003-07-24 | 2009-01-31 | Merck & Co Inc | Polypeptides for inducing a protective immune response against staphylococcus aureus |
| ES2730275T3 (es) * | 2004-09-22 | 2019-11-11 | Glaxosmithkline Biologicals Sa | Composición inmunógena para uso en vacunación contra estafilococos |
-
2005
- 2005-12-21 GB GB0526038A patent/GB0526038D0/en not_active Ceased
-
2006
- 2006-12-19 CA CA 2634898 patent/CA2634898A1/en not_active Abandoned
- 2006-12-19 WO PCT/EP2006/069944 patent/WO2007071692A2/en not_active Ceased
- 2006-12-19 ES ES06830724.8T patent/ES2558703T3/es active Active
- 2006-12-19 US US12/097,820 patent/US20080311146A1/en not_active Abandoned
- 2006-12-19 JP JP2008546433A patent/JP5780693B2/ja not_active Expired - Fee Related
- 2006-12-19 EP EP06830724.8A patent/EP1962890B1/en active Active
-
2013
- 2013-06-04 JP JP2013117514A patent/JP2013215197A/ja active Pending
-
2015
- 2015-01-15 US US14/598,221 patent/US20150125481A1/en not_active Abandoned
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