JP2009520758A5 - - Google Patents
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- Publication number
- JP2009520758A5 JP2009520758A5 JP2008546433A JP2008546433A JP2009520758A5 JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5 JP 2008546433 A JP2008546433 A JP 2008546433A JP 2008546433 A JP2008546433 A JP 2008546433A JP 2009520758 A5 JP2009520758 A5 JP 2009520758A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- binding domain
- polypeptide
- igg binding
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002163 immunogen Effects 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 12
- 102000004196 processed proteins & peptides Human genes 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 125000003275 alpha amino acid group Chemical group 0.000 claims 7
- 108090000623 proteins and genes Proteins 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 7
- 108091033319 polynucleotide Proteins 0.000 claims 4
- 102000040430 polynucleotide Human genes 0.000 claims 4
- 239000002157 polynucleotide Substances 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 3
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 210000002925 A-like Anatomy 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000005847 immunogenicity Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0526038A GB0526038D0 (en) | 2005-12-21 | 2005-12-21 | Immunogenic composition |
| GB0526038.5 | 2005-12-21 | ||
| PCT/EP2006/069944 WO2007071692A2 (en) | 2005-12-21 | 2006-12-19 | Immunogenic composition |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Division JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520758A JP2009520758A (ja) | 2009-05-28 |
| JP2009520758A5 true JP2009520758A5 (enExample) | 2010-02-12 |
| JP5780693B2 JP5780693B2 (ja) | 2015-09-16 |
Family
ID=35840898
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546433A Expired - Fee Related JP5780693B2 (ja) | 2005-12-21 | 2006-12-19 | 免疫原性組成物 |
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013117514A Pending JP2013215197A (ja) | 2005-12-21 | 2013-06-04 | 免疫原性組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20080311146A1 (enExample) |
| EP (1) | EP1962890B1 (enExample) |
| JP (2) | JP5780693B2 (enExample) |
| CA (1) | CA2634898A1 (enExample) |
| ES (1) | ES2558703T3 (enExample) |
| GB (1) | GB0526038D0 (enExample) |
| WO (1) | WO2007071692A2 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0610776D0 (en) * | 2006-05-31 | 2006-07-12 | Univ Bath | Novel applications for staphylococcus aureus Sbi protein |
| WO2008127457A2 (en) | 2006-12-06 | 2008-10-23 | Repligen Corporation | Nucleic acids encoding recombinant protein a |
| PT3281947T (pt) | 2009-04-03 | 2020-05-07 | Univ Chicago | Composições e métodos relacionados com variantes da proteína a (spa) |
| WO2010119343A2 (en) | 2009-04-14 | 2010-10-21 | Novartis Ag | Compositions for immunising against staphylococcus aureus |
| ES2812523T3 (es) | 2009-09-30 | 2021-03-17 | Glaxosmithkline Biologicals Sa | Conjugación de polisacáridos capsulares de Staphylococcus aureus de tipo 5 y de tipo 8 |
| MX345967B (es) | 2009-10-30 | 2017-02-28 | Novartis Ag | Purificacion de sacaridos capsulares de staphylococcus aureus tipo 5 y tipo 8. |
| EP2588120B1 (en) * | 2010-07-02 | 2017-11-15 | The University of Chicago | Compositions and methods related to protein a (spa) variants |
| EP2614074A1 (en) * | 2010-09-09 | 2013-07-17 | The University of Chicago | Methods and compositions involving protective staphylococcal antigens |
| US9988439B2 (en) | 2011-12-23 | 2018-06-05 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| EP2793944B1 (en) | 2011-12-23 | 2025-10-08 | Nicholas B. Lydon | Immunoglobulins and variants directed against pathogenic microbes |
| CN102698260B (zh) * | 2012-04-20 | 2013-09-25 | 西北农林科技大学 | 预防山羊葡萄球菌乳房炎的亚单位疫苗的制备方法及应用 |
| WO2015073801A1 (en) * | 2013-11-14 | 2015-05-21 | Duke University | Tetanus toxoid and ccl3 improve dc vaccines |
| JP2016540764A (ja) * | 2013-12-04 | 2016-12-28 | グリコヴァキシン アーゲー | 大腸菌で合成された糖タンパク質ワクチンによる黄色ブドウ球菌感染の予防 |
| CN103694322B (zh) * | 2013-12-09 | 2016-08-17 | 成都欧林生物科技股份有限公司 | 金黄色葡萄球菌SpA5突变体及其制备方法和应用 |
| EA037818B1 (ru) | 2014-03-26 | 2021-05-25 | Глаксосмитклайн Байолоджикалс С.А. | Мутантные стафилококковые антигены |
| GB201619965D0 (en) * | 2016-11-25 | 2017-01-11 | Univ Of Bath The | Immunogenic compositions comprising sbi protein and uses thereof |
| GB201802339D0 (en) | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| BR112021022902A2 (pt) | 2019-05-14 | 2022-01-25 | Univ Chicago | Métodos e composições que compreendem variantes de proteína a staphylococcus (spa) |
| EP3777884A1 (en) * | 2019-08-15 | 2021-02-17 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| US20230210967A1 (en) * | 2020-04-23 | 2023-07-06 | Brightpath Biotherapeutics Co., Ltd. | Improved peptide vaccine |
| WO2024129976A2 (en) * | 2022-12-14 | 2024-06-20 | Scribe Therapeutics Inc. | Particle delivery systems |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5571514A (en) * | 1987-06-01 | 1996-11-05 | Alfa Laval Ab | Fibronectin binding protein as well as its preparation |
| SE9704141D0 (sv) * | 1997-11-12 | 1997-11-12 | Sbl Vaccin Ab | New protein and nucleotide sequence, encoding said protein |
| KR100644953B1 (ko) | 1998-08-31 | 2006-11-10 | 인히비텍스, 인코포레이티드 | 다성분 백신 |
| WO2000012132A1 (en) | 1998-08-31 | 2000-03-09 | Inhibitex, Inc. | Staphylococcal immunotherapeutics via donor selection and donor stimulation |
| CA2344166C (en) | 1998-09-14 | 2008-11-18 | Nabi | Compositions of .beta.-glucans and specific igiv |
| US7098383B2 (en) * | 2000-12-19 | 2006-08-29 | Sembiosys Genetics Inc. | Methods for the production of multimeric immunoglobulins, and related compositions |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US9296795B2 (en) * | 2003-03-07 | 2016-03-29 | Wyeth Holdings, Llc. | Polysaccharide-staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections |
| US20050137220A1 (en) * | 2003-07-23 | 2005-06-23 | Pharmacia Corporation | Beta-carboline compounds and analogues thereof as mitogen-activated protein kinase-activated protein kinase-2 inhibitors |
| RU2337108C2 (ru) * | 2003-07-24 | 2008-10-27 | Мерк Энд Ко., Инк. | Полипептиды для индукции защитного иммунного ответа против staphylococcus aureus |
| JP2008513406A (ja) * | 2004-09-22 | 2008-05-01 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 免疫原性組成物 |
-
2005
- 2005-12-21 GB GB0526038A patent/GB0526038D0/en not_active Ceased
-
2006
- 2006-12-19 US US12/097,820 patent/US20080311146A1/en not_active Abandoned
- 2006-12-19 ES ES06830724.8T patent/ES2558703T3/es active Active
- 2006-12-19 EP EP06830724.8A patent/EP1962890B1/en active Active
- 2006-12-19 JP JP2008546433A patent/JP5780693B2/ja not_active Expired - Fee Related
- 2006-12-19 CA CA 2634898 patent/CA2634898A1/en not_active Abandoned
- 2006-12-19 WO PCT/EP2006/069944 patent/WO2007071692A2/en not_active Ceased
-
2013
- 2013-06-04 JP JP2013117514A patent/JP2013215197A/ja active Pending
-
2015
- 2015-01-15 US US14/598,221 patent/US20150125481A1/en not_active Abandoned
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