JP2008508859A5 - - Google Patents
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- Publication number
- JP2008508859A5 JP2008508859A5 JP2007513935A JP2007513935A JP2008508859A5 JP 2008508859 A5 JP2008508859 A5 JP 2008508859A5 JP 2007513935 A JP2007513935 A JP 2007513935A JP 2007513935 A JP2007513935 A JP 2007513935A JP 2008508859 A5 JP2008508859 A5 JP 2008508859A5
- Authority
- JP
- Japan
- Prior art keywords
- binding molecule
- seq
- pharmaceutical composition
- rabies virus
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57502304P | 2004-05-27 | 2004-05-27 | |
| EPPCT/EP2004/050943 | 2004-05-27 | ||
| EP2004050943 | 2004-05-27 | ||
| US60/575,023 | 2004-05-27 | ||
| EPPCT/EP2004/051661 | 2004-07-29 | ||
| EP2004051661 | 2004-07-29 | ||
| EPPCT/EP2004/052286 | 2004-09-23 | ||
| EP2004052286 | 2004-09-23 | ||
| EP2004052772 | 2004-11-03 | ||
| EPPCT/EP2004/052772 | 2004-11-03 | ||
| EP2005050310 | 2005-01-25 | ||
| EPPCT/EP2005/050310 | 2005-01-25 | ||
| EP2005050953 | 2005-03-03 | ||
| EPPCT/EP2005/050953 | 2005-03-03 | ||
| PCT/EP2005/052410 WO2005118644A2 (en) | 2004-05-27 | 2005-05-26 | Binding molecules capable of neutralizing rabies virus and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008508859A JP2008508859A (ja) | 2008-03-27 |
| JP2008508859A5 true JP2008508859A5 (enExample) | 2008-07-10 |
| JP4768730B2 JP4768730B2 (ja) | 2011-09-07 |
Family
ID=34968690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007513935A Expired - Fee Related JP4768730B2 (ja) | 2004-05-27 | 2005-05-26 | 狂犬病ウイルスを中和することができる結合分子およびそれらの用途 |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US7579446B2 (enExample) |
| EP (3) | EP2314621B1 (enExample) |
| JP (1) | JP4768730B2 (enExample) |
| KR (2) | KR101456770B1 (enExample) |
| CN (5) | CN102212132A (enExample) |
| AT (1) | ATE501171T1 (enExample) |
| AU (1) | AU2005250163B2 (enExample) |
| BR (1) | BRPI0511479C1 (enExample) |
| CA (1) | CA2568162C (enExample) |
| CU (1) | CU23719A3 (enExample) |
| CY (1) | CY1111550T1 (enExample) |
| DK (1) | DK1749029T3 (enExample) |
| EA (1) | EA010785B1 (enExample) |
| ES (2) | ES2468021T3 (enExample) |
| HR (3) | HRP20110320T1 (enExample) |
| IL (3) | IL179586A (enExample) |
| MX (1) | MXPA06013482A (enExample) |
| NZ (2) | NZ580607A (enExample) |
| PL (3) | PL1749029T3 (enExample) |
| PT (3) | PT1749029E (enExample) |
| RS (2) | RS53269B (enExample) |
| WO (1) | WO2005118644A2 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| DE60317677T2 (de) * | 2002-06-13 | 2008-10-30 | Crucell Holland B.V. | Ox40 (=cd134) rezeptor agonisten und therapeutische verwendung |
| EP1539235A2 (en) | 2002-07-01 | 2005-06-15 | Human Genome Sciences, Inc. | Antibodies that specifically bind to reg iv |
| PT2314629E (pt) | 2002-07-18 | 2014-01-22 | Merus B V | Produção recombinante de misturas de anticorpos |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| EP2395016A3 (en) | 2003-05-30 | 2012-12-19 | Merus B.V. | Design and use of paired variable regions of specific binding molecules |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| EP2322547A1 (en) | 2003-06-25 | 2011-05-18 | Crucell Holland B.V. | Myeloid cell-specific lectin |
| SG128680A1 (en) * | 2003-07-22 | 2007-01-30 | Crucell Holland Bv | Binding molecules against sars-coronavirus and uses thereof |
| NZ580607A (en) * | 2004-05-27 | 2011-05-27 | Crucell Holland Bv | Binding molecules capable of neutralizing rabies virus and uses thereof |
| CA2579523C (en) * | 2004-10-12 | 2016-04-12 | Crucell Holland B.V. | Atad3a-binding molecules for treatment, detection and prevention of cancer |
| US8052974B2 (en) | 2005-05-12 | 2011-11-08 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
| AU2006290736B2 (en) * | 2005-09-15 | 2011-09-15 | Crucell Holland B.V. | Method for preparing immunoglobulin libraries |
| US7807645B2 (en) | 2005-09-23 | 2010-10-05 | The Regents Of The University Of California | Method of treating degenerative disorders of the nervous system by administration of fibrinogen fragment |
| EA018030B1 (ru) | 2006-06-06 | 2013-05-30 | Круселл Холланд Б.В. | Связывающие молекулы человека, имеющие убивающую активность против стафилококков, и их применения |
| WO2007141278A2 (en) | 2006-06-06 | 2007-12-13 | Crucell Holland B.V. | Human binding molecules having killing activity against enterococci and staphylococcus aureus and uses thereof |
| CA2663388C (en) | 2006-09-07 | 2017-01-17 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| AU2007328960B2 (en) * | 2006-12-05 | 2013-01-17 | Crucell Holland B.V. | Liquid anti-rabies antibody formulations |
| DK2158315T3 (en) | 2007-06-25 | 2016-06-06 | Esbatech Alcon Biomed Res Unit | Methods of modifying antibodies and modified antibodies with improved functional properties |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| WO2010132532A1 (en) | 2009-05-15 | 2010-11-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | B cell surface reactive antibodies |
| US8821879B2 (en) | 2009-09-04 | 2014-09-02 | Xoma Technology Ltd. | Anti-botulism antibody coformulations |
| EA023477B1 (ru) * | 2009-10-02 | 2016-06-30 | Дзе Реджентс Оф Дзе Юниверсити Оф Калифорния | МОНОКЛОНАЛЬНОЕ АНТИТЕЛО, СВЯЗЫВАЮЩЕЕ ДОМЕН γ-С ФИБРИНА ИЛИ ФИБРИНОГЕНА |
| CN101696242B (zh) * | 2009-10-26 | 2011-12-28 | 中国人民解放军南京军区军事医学研究所 | 人源抗狂犬病毒中和抗体Fab及其制备方法和应用 |
| WO2011080765A2 (en) * | 2010-01-04 | 2011-07-07 | Indian Immunologicals Limited | Recombinant human bivalent diabody against rabies virus and uses thereof |
| EP2537931B1 (en) * | 2010-02-19 | 2016-10-19 | Japan Science And Technology Agency | Antiviral abzyme |
| SG183443A1 (en) | 2010-03-01 | 2012-09-27 | Bayer Healthcare Llc | Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
| ES2993335T3 (en) | 2010-03-10 | 2024-12-27 | Genmab As | Monoclonal antibodies against c-met |
| JP2013538042A (ja) * | 2010-06-16 | 2013-10-10 | ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | エンドプラスミンに対する抗体およびその使用 |
| KR101388680B1 (ko) * | 2011-03-18 | 2014-04-28 | (주)셀트리온 | 광견병 바이러스를 중화시킬 수 있는 결합 분자 |
| CA2791109C (en) | 2011-09-26 | 2021-02-16 | Merus B.V. | Generation of binding molecules |
| WO2013048130A2 (ko) * | 2011-09-30 | 2013-04-04 | (주)셀트리온 | 광견병 바이러스를 중화시킬 수 있는 결합 분자 |
| DK2838917T3 (da) | 2012-04-20 | 2019-08-26 | Merus Nv | Fremgangsmåder og midler til frembringelse af heterodimere ig-lignende molekyler |
| CN102924571A (zh) * | 2012-10-29 | 2013-02-13 | 复旦大学 | 狂犬病毒糖蛋白与核蛋白的抗原表位多肽及其筛选、鉴定方法与应用 |
| CN105814077B (zh) * | 2013-12-12 | 2019-07-26 | 赛特瑞恩股份有限公司 | 能够中和狂犬病毒的结合分子 |
| CN103954777A (zh) * | 2014-05-20 | 2014-07-30 | 北京凯思百奥科技发展有限公司 | 一种狂犬病病毒单克隆抗体及其应用 |
| RU2549971C1 (ru) * | 2014-07-01 | 2015-05-10 | Федеральное казённое учреждение здравоохранения Ставропольский научно-исследовательский противочумный институт Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Способ консервации иммунопероксидазного конъюгата |
| CN104761640A (zh) * | 2015-02-03 | 2015-07-08 | 中国食品药品检定研究院 | 具有中和活性的抗狂犬病病毒单克隆抗体的制备及应用 |
| CA2976446A1 (en) * | 2015-02-13 | 2016-08-18 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind ctla4 |
| WO2016200189A1 (ko) * | 2015-06-10 | 2016-12-15 | (주)셀트리온 | 광견병 바이러스 g 단백질의 에피토프 및 이에 특이적으로 결합하는 광견병 바이러스 중화 결합 분자 |
| WO2017124001A2 (en) * | 2016-01-14 | 2017-07-20 | Memorial Sloan-Kettering Cancer Center | T cell receptor-like antibodies specific for foxp3-derived peptides |
| JOP20190248A1 (ar) * | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| RU2718835C2 (ru) * | 2017-12-29 | 2020-04-15 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Нейтрализующее моноклональное антитело, связывающееся с гликопротеином g вируса бешенства, фрагменты днк, кодирующие указанное антитело, и антигенсвязывающий фрагмент |
| WO2019227039A1 (en) * | 2018-05-24 | 2019-11-28 | Lankenau Institute For Medical Research | Compositions comprising antibodies to rabies virus and the uses thereof |
| US11773155B2 (en) | 2018-08-09 | 2023-10-03 | Beijing Wisdomab Biotechnology Co., Ltd | Bispecific antibody against rabies virus, and application thereof |
| WO2020239005A1 (zh) * | 2019-05-30 | 2020-12-03 | 山东博安生物技术有限公司 | 靶向Claudin18.2的抗体或嵌合抗原受体 |
| CN111171145B (zh) * | 2020-01-21 | 2021-11-05 | 兰州生物制品研究所有限责任公司 | 一种抗狂犬病病毒单克隆抗体、制备方法及用途 |
| WO2021242815A1 (en) * | 2020-05-26 | 2021-12-02 | Regeneron Pharmaceuticals, Inc. | Anti-sars-cov-2-spike glycoprotein antibodies and antigen-binding fragments |
| US20250084163A1 (en) * | 2021-04-09 | 2025-03-13 | Sorrento Therapeutics, Inc. | Antigen Binding Proteins That Bind ROR1 |
| CN114397453B (zh) * | 2022-03-25 | 2022-06-07 | 江苏美克医学技术有限公司 | 新型冠状病毒突变株的检测试剂盒及其应用 |
| CN118290572A (zh) * | 2023-09-19 | 2024-07-05 | 军事科学院军事医学研究院军事兽医研究所 | 抗狂犬病病毒全人源抗体及其组合物与应用 |
| CN119930826A (zh) * | 2023-11-02 | 2025-05-06 | 重庆精准生物产业技术研究院有限公司 | 针对psca的全人源单链抗体及其应用 |
| CN117777282B (zh) * | 2023-12-07 | 2025-03-04 | 兰州生物制品研究所有限责任公司 | 一种抗狂犬病病毒中和抗体及其制备和应用 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
| ATE99958T1 (de) * | 1989-06-08 | 1994-01-15 | Wistar Inst | Monoklonale antikoerper zur behandlung nach einem kontakt mit tollwutvirus. |
| DE4006630A1 (de) | 1990-03-03 | 1991-09-12 | Behringwerke Ag | Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung |
| NL9101953A (nl) | 1991-11-21 | 1993-06-16 | Seed Capital Investments | Testinrichting omvattende een plaat met een veelvoud van putjes met een bijbehorende doseerinrichting, alsmede een kit die deze inrichtingen omvat en toepassing van de inrichtingen. |
| US5624949A (en) | 1993-12-07 | 1997-04-29 | Eli Lilly And Company | Protein kinase C inhibitors |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| DK0934526T3 (da) * | 1996-10-08 | 2003-05-05 | Bisys B V U | Fremgangsmåder og midler til udvælgelse af peptider og proteiner, der har specifik affinitet til et mål |
| ES2237420T5 (es) | 1999-04-15 | 2010-03-03 | Crucell Holland B.V. | Produccion de proteina recombinante en una celula humana. |
| US7071319B2 (en) * | 2000-05-16 | 2006-07-04 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
| US20040013672A1 (en) * | 2000-05-16 | 2004-01-22 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
| WO2002103012A1 (en) | 2001-06-15 | 2002-12-27 | Crucell Holland B.V. | Chimaeric phages |
| RU2292353C2 (ru) * | 2001-08-21 | 2007-01-27 | Томас Джефферсон Юниверсити | Рекомбинантные антитела и композиции, а также способы их создания и использования |
| DE60317677T2 (de) * | 2002-06-13 | 2008-10-30 | Crucell Holland B.V. | Ox40 (=cd134) rezeptor agonisten und therapeutische verwendung |
| PT2314629E (pt) * | 2002-07-18 | 2014-01-22 | Merus B V | Produção recombinante de misturas de anticorpos |
| US20100069614A1 (en) * | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| EP2322547A1 (en) | 2003-06-25 | 2011-05-18 | Crucell Holland B.V. | Myeloid cell-specific lectin |
| SG128680A1 (en) | 2003-07-22 | 2007-01-30 | Crucell Holland Bv | Binding molecules against sars-coronavirus and uses thereof |
| JP5744369B2 (ja) | 2004-02-27 | 2015-07-08 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | IL15−Rα用IL−15結合部位およびアゴニスト/アンタゴニスト活性を有する特異的IL−15突然変異体 |
| NZ580607A (en) | 2004-05-27 | 2011-05-27 | Crucell Holland Bv | Binding molecules capable of neutralizing rabies virus and uses thereof |
| NZ553701A (en) | 2004-11-11 | 2009-12-24 | Crucell Holland Bv | Composition comprising SC03-014 and SC03-022 antibodies against SARS-CoV |
| CA2591665C (en) | 2004-12-20 | 2015-05-05 | Crucell Holland B.V. | Binding molecules capable of neutralizing west nile virus and uses thereof |
| CN101166763B (zh) | 2005-04-18 | 2012-09-19 | 伊达研究和发展有限公司 | 稳定的抗乙肝病毒(hbv)抗体配制剂 |
| US8052974B2 (en) | 2005-05-12 | 2011-11-08 | Crucell Holland B.V. | Host cell specific binding molecules capable of neutralizing viruses and uses thereof |
| EP1893645A1 (en) | 2005-06-23 | 2008-03-05 | Crucell Holland B.V. | Optimization of west nile virus antibodies |
| KR20080100271A (ko) * | 2006-02-27 | 2008-11-14 | 엘란 파마슈티칼스, 인크. | Vla-4에 의해 매개되는 백혈구 부착을 억제하는 피리미디닐 술폰아미드 화합물 |
| WO2007141278A2 (en) * | 2006-06-06 | 2007-12-13 | Crucell Holland B.V. | Human binding molecules having killing activity against enterococci and staphylococcus aureus and uses thereof |
| EA018030B1 (ru) * | 2006-06-06 | 2013-05-30 | Круселл Холланд Б.В. | Связывающие молекулы человека, имеющие убивающую активность против стафилококков, и их применения |
| CA2663388C (en) * | 2006-09-07 | 2017-01-17 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus h5n1 and uses thereof |
| AU2007328960B2 (en) * | 2006-12-05 | 2013-01-17 | Crucell Holland B.V. | Liquid anti-rabies antibody formulations |
-
2005
- 2005-05-26 NZ NZ580607A patent/NZ580607A/en not_active IP Right Cessation
- 2005-05-26 KR KR1020127030900A patent/KR101456770B1/ko not_active Expired - Fee Related
- 2005-05-26 WO PCT/EP2005/052410 patent/WO2005118644A2/en not_active Ceased
- 2005-05-26 EA EA200602210A patent/EA010785B1/ru unknown
- 2005-05-26 CN CN2011100709086A patent/CN102212132A/zh active Pending
- 2005-05-26 NZ NZ550366A patent/NZ550366A/en not_active IP Right Cessation
- 2005-05-26 PT PT05747901T patent/PT1749029E/pt unknown
- 2005-05-26 PT PT101803989T patent/PT2314621E/pt unknown
- 2005-05-26 JP JP2007513935A patent/JP4768730B2/ja not_active Expired - Fee Related
- 2005-05-26 EP EP10180398.9A patent/EP2314621B1/en not_active Expired - Lifetime
- 2005-05-26 CN CN201110070883XA patent/CN102212131B/zh not_active Expired - Fee Related
- 2005-05-26 CN CN2005800172331A patent/CN1961002B/zh not_active Expired - Fee Related
- 2005-05-26 CA CA2568162A patent/CA2568162C/en not_active Expired - Fee Related
- 2005-05-26 EP EP10180375.7A patent/EP2314620B1/en not_active Expired - Lifetime
- 2005-05-26 CN CN201110071403.1A patent/CN102139106B/zh not_active Expired - Fee Related
- 2005-05-26 EP EP05747901A patent/EP1749029B1/en not_active Expired - Lifetime
- 2005-05-26 ES ES10180398.9T patent/ES2468021T3/es not_active Expired - Lifetime
- 2005-05-26 PL PL05747901T patent/PL1749029T3/pl unknown
- 2005-05-26 PL PL10180398T patent/PL2314621T3/pl unknown
- 2005-05-26 AT AT05747901T patent/ATE501171T1/de active
- 2005-05-26 CN CN201110070931.5A patent/CN102241769B/zh not_active Expired - Fee Related
- 2005-05-26 PL PL10180375T patent/PL2314620T3/pl unknown
- 2005-05-26 RS RS20140221A patent/RS53269B/sr unknown
- 2005-05-26 MX MXPA06013482A patent/MXPA06013482A/es active IP Right Grant
- 2005-05-26 PT PT101803757T patent/PT2314620E/pt unknown
- 2005-05-26 DK DK05747901.6T patent/DK1749029T3/da active
- 2005-05-26 ES ES10180375T patent/ES2426725T3/es not_active Expired - Lifetime
- 2005-05-26 HR HR20110320T patent/HRP20110320T1/hr unknown
- 2005-05-26 BR BRPI0511479-9 patent/BRPI0511479C1/pt not_active IP Right Cessation
- 2005-05-26 KR KR1020067024277A patent/KR101228157B1/ko not_active Expired - Fee Related
- 2005-05-26 AU AU2005250163A patent/AU2005250163B2/en not_active Ceased
- 2005-05-26 RS RS20110240A patent/RS51847B/sr unknown
-
2006
- 2006-10-31 US US11/590,126 patent/US7579446B2/en not_active Expired - Lifetime
- 2006-11-26 IL IL179586A patent/IL179586A/en active IP Right Grant
- 2006-11-27 CU CU20060230A patent/CU23719A3/es not_active IP Right Cessation
-
2007
- 2007-10-29 US US11/978,742 patent/US7740852B2/en not_active Expired - Fee Related
- 2007-10-29 US US11/980,237 patent/US20080070799A1/en not_active Abandoned
-
2009
- 2009-07-06 US US12/459,661 patent/US8148497B2/en not_active Expired - Fee Related
- 2009-11-05 IL IL201970A patent/IL201970A/en active IP Right Grant
-
2010
- 2010-04-08 US US12/798,748 patent/US9005624B2/en not_active Expired - Fee Related
-
2011
- 2011-06-08 CY CY20111100548T patent/CY1111550T1/el unknown
-
2013
- 2013-04-18 IL IL225849A patent/IL225849A0/en active IP Right Grant
- 2013-08-07 HR HRP20130750TT patent/HRP20130750T1/hr unknown
-
2014
- 2014-05-08 HR HRP20140419TT patent/HRP20140419T1/hr unknown
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