JP2010166916A5 - - Google Patents
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- JP2010166916A5 JP2010166916A5 JP2010031866A JP2010031866A JP2010166916A5 JP 2010166916 A5 JP2010166916 A5 JP 2010166916A5 JP 2010031866 A JP2010031866 A JP 2010031866A JP 2010031866 A JP2010031866 A JP 2010031866A JP 2010166916 A5 JP2010166916 A5 JP 2010166916A5
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- JP
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- Prior art keywords
- protein
- nucleic acid
- composition
- acid molecule
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000039446 nucleic acids Human genes 0.000 claims 11
- 108020004707 nucleic acids Proteins 0.000 claims 11
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 102000004169 proteins and genes Human genes 0.000 claims 11
- 108090000623 proteins and genes Proteins 0.000 claims 11
- 239000012634 fragment Substances 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 230000000295 complement effect Effects 0.000 claims 3
- 230000002163 immunogen Effects 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 241000588650 Neisseria meningitidis Species 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8375898P | 1998-05-01 | 1998-05-01 | |
| US9486998P | 1998-07-31 | 1998-07-31 | |
| US9899498P | 1998-09-02 | 1998-09-02 | |
| US9906298P | 1998-09-02 | 1998-09-02 | |
| US10379498P | 1998-10-09 | 1998-10-09 | |
| US10379698P | 1998-10-09 | 1998-10-09 | |
| US10374998P | 1998-10-09 | 1998-10-09 | |
| US12152899P | 1999-02-25 | 1999-02-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000547235A Division JP5102414B2 (ja) | 1998-05-01 | 1999-04-30 | 髄膜炎菌抗原および組成物 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012140208A Division JP2012191946A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
| JP2012140207A Division JP2012191945A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010166916A JP2010166916A (ja) | 2010-08-05 |
| JP2010166916A5 true JP2010166916A5 (enExample) | 2011-04-07 |
Family
ID=27574612
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000547235A Expired - Fee Related JP5102414B2 (ja) | 1998-05-01 | 1999-04-30 | 髄膜炎菌抗原および組成物 |
| JP2009125889A Withdrawn JP2009183306A (ja) | 1998-05-01 | 2009-05-25 | 髄膜炎菌抗原および組成物 |
| JP2010031866A Withdrawn JP2010166916A (ja) | 1998-05-01 | 2010-02-16 | 髄膜炎菌抗原および組成物 |
| JP2012140207A Pending JP2012191945A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
| JP2012140208A Withdrawn JP2012191946A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
| JP2013157834A Expired - Lifetime JP6025674B2 (ja) | 1998-05-01 | 2013-07-30 | 髄膜炎菌抗原および組成物 |
| JP2013157835A Expired - Lifetime JP6025675B2 (ja) | 1998-05-01 | 2013-07-30 | 髄膜炎菌抗原および組成物 |
| JP2016154472A Withdrawn JP2016222709A (ja) | 1998-05-01 | 2016-08-05 | 髄膜炎菌抗原および組成物 |
| JP2016192774A Withdrawn JP2017012195A (ja) | 1998-05-01 | 2016-09-30 | 髄膜炎菌抗原および組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000547235A Expired - Fee Related JP5102414B2 (ja) | 1998-05-01 | 1999-04-30 | 髄膜炎菌抗原および組成物 |
| JP2009125889A Withdrawn JP2009183306A (ja) | 1998-05-01 | 2009-05-25 | 髄膜炎菌抗原および組成物 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012140207A Pending JP2012191945A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
| JP2012140208A Withdrawn JP2012191946A (ja) | 1998-05-01 | 2012-06-21 | 髄膜炎菌抗原および組成物 |
| JP2013157834A Expired - Lifetime JP6025674B2 (ja) | 1998-05-01 | 2013-07-30 | 髄膜炎菌抗原および組成物 |
| JP2013157835A Expired - Lifetime JP6025675B2 (ja) | 1998-05-01 | 2013-07-30 | 髄膜炎菌抗原および組成物 |
| JP2016154472A Withdrawn JP2016222709A (ja) | 1998-05-01 | 2016-08-05 | 髄膜炎菌抗原および組成物 |
| JP2016192774A Withdrawn JP2017012195A (ja) | 1998-05-01 | 2016-09-30 | 髄膜炎菌抗原および組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (9) | US7576176B1 (enExample) |
| EP (23) | EP1944371B1 (enExample) |
| JP (9) | JP5102414B2 (enExample) |
| CN (3) | CN101293920B (enExample) |
| AT (2) | ATE388230T1 (enExample) |
| AU (1) | AU761780B2 (enExample) |
| BR (1) | BR9910089A (enExample) |
| CA (2) | CA2330838C (enExample) |
| CY (2) | CY1109649T1 (enExample) |
| DE (2) | DE69937419T2 (enExample) |
| DK (2) | DK1093517T3 (enExample) |
| ES (3) | ES2537575T3 (enExample) |
| MX (4) | MX343744B (enExample) |
| NZ (4) | NZ527182A (enExample) |
| PT (3) | PT1944371E (enExample) |
| WO (1) | WO1999057280A2 (enExample) |
Families Citing this family (204)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT909323E (pt) | 1996-01-04 | 2007-06-04 | Novartis Vaccines & Diagnostic | ''bacterioferritina de helicobacter pilori'' |
| CA2266656A1 (en) | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
| AU9363798A (en) * | 1997-11-06 | 1999-05-31 | Chiron S.P.A. | Neisserial antigens |
| US6914131B1 (en) | 1998-10-09 | 2005-07-05 | Chiron S.R.L. | Neisserial antigens |
| WO2001031019A2 (en) | 1999-10-29 | 2001-05-03 | Chiron Spa | Neisserial antigenic peptides |
| US20070026021A1 (en) * | 1998-05-01 | 2007-02-01 | Chiron S.R.I. | Neisseria meningitidis antigens and compositions |
| PT1944371E (pt) | 1998-05-01 | 2015-07-13 | Novartis Ag | Antigénios e composições da neisseria meningitidis |
| US6693186B2 (en) | 1998-09-01 | 2004-02-17 | Antex Biologics Inc | Neisseria meningitidis polypeptide, nucleic acid sequence and uses thereof |
| US6756493B1 (en) | 1998-09-01 | 2004-06-29 | Antex Biologics, Inc. | Nucleic acid sequence and uses thereof |
| US6610306B2 (en) | 1998-10-22 | 2003-08-26 | The University Of Montana | OMP85 protein of neisseria meningitidis, compositions containing the same and methods of use thereof |
| GB9826886D0 (en) * | 1998-12-07 | 1999-01-27 | Smithkline Beecham Biolog | Novel compounds |
| EP2374889A3 (en) * | 1998-12-08 | 2012-02-22 | GlaxoSmithKline Biologicals SA | Novel compounds |
| EP1144645A1 (en) * | 1999-01-15 | 2001-10-17 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Neisseria meningitidis polypeptide basb052 |
| WO2000042193A1 (en) * | 1999-01-15 | 2000-07-20 | Smithkline Beecham Biologicals S.A. | Neisseria meningitidis antigen |
| CA2360667A1 (en) | 1999-01-22 | 2000-07-27 | Smithkline Beecham Biologicals S.A. | Neisseria meningitidis basb054 polypeptides and encoding polynucleotides and uses thereof |
| CA2360658A1 (en) * | 1999-01-22 | 2000-07-27 | Smithkline Beecham Biologicals S.A. | Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies |
| GB9902084D0 (en) * | 1999-01-29 | 1999-03-24 | Smithkline Beecham Biolog | Novel compounds |
| GB9902937D0 (en) * | 1999-02-10 | 1999-03-31 | Smithkline Beecham Biolog | Novel compounds |
| ATE279943T1 (de) * | 1999-02-26 | 2004-11-15 | Chiron Srl | Verbesserung der bakterizidaktivität von neisseria antigenen mit cg enthaltende oligonukleotiden |
| AU3164600A (en) | 1999-03-12 | 2000-10-04 | Smithkline Beecham Biologicals (Sa) | Novel compounds |
| EP2290083B1 (en) * | 1999-04-30 | 2014-08-20 | Novartis Vaccines and Diagnostics S.r.l. | Conserved neisserial antigens |
| AU2004240199B2 (en) * | 1999-04-30 | 2007-05-17 | Novartis Vaccines And Diagnostics S.R.L. | Conserved Neisserial antigens |
| AU2013203304B2 (en) * | 1999-05-19 | 2014-10-09 | Glaxosmithkline Biologicals S.A. | Combination Neisserial compositions |
| EP1860191A3 (en) * | 1999-05-19 | 2008-02-13 | Novartis Vaccines and Diagnostics S.r.l. | Combination neisserial compositions |
| GB9911683D0 (en) * | 1999-05-19 | 1999-07-21 | Chiron Spa | Antigenic peptides |
| AU2013200678B2 (en) * | 1999-05-19 | 2014-08-21 | Glaxosmithkline Biologicals S.A. | Combination Neisserial compositions |
| AU2003271337B2 (en) * | 1999-08-03 | 2005-07-21 | Smithkline Beecham Biologicals S.A. | Vaccine composition |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| AU1875301A (en) | 1999-11-29 | 2001-06-04 | Chiron S.P.A. | 85kda neisserial antigen |
| JP2003520248A (ja) | 2000-01-17 | 2003-07-02 | カイロン エセ．ピー．アー． | Ｎ．ｍｅｎｉｎｇｉｔｉｄｉｓ血清型ｂ外膜タンパク質を含む外膜小胞（ｏｍｖ）ワクチン |
| BR0107857A (pt) | 2000-01-25 | 2002-10-29 | Univ Queensland | Proteìnas compreendendo regiões conservadas de antìgeno nhha de superfìcie de neisseria meningitidis |
| EP1790660B1 (en) | 2000-02-28 | 2012-06-20 | Novartis Vaccines and Diagnostics S.r.l. | Heterologous expression of neisserial proteins |
| WO2002009643A2 (en) | 2000-07-27 | 2002-02-07 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
| NZ594877A (en) | 2000-10-27 | 2012-07-27 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
| US7250172B2 (en) | 2001-01-31 | 2007-07-31 | University Of Iowa Research Foundation | Vaccine and compositions for the prevention and treatment of neisserial infections |
| US7261901B2 (en) | 2001-01-31 | 2007-08-28 | University Of Iowa Research Foundation | Vaccine and compositions for the prevention and treatment of neisserial infections |
| GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| GB0107661D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| GB0107658D0 (en) | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
| CN1306956C (zh) * | 2001-04-17 | 2007-03-28 | 希龙公司 | 诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物 |
| ATE472335T1 (de) | 2001-05-31 | 2010-07-15 | Novartis Vaccines & Diagnostic | Chimere alphavirus-replikon-partikel |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| WO2003010194A2 (en) | 2001-07-27 | 2003-02-06 | Chiron Srl. | Meningococcus adhesins nada, app and orf 40 |
| AU2012202488B2 (en) * | 2001-09-06 | 2014-01-16 | Glaxosmithkline Biologicals S.A. | Hybrid and tandem expression of Neisserial proteins |
| US7838015B2 (en) * | 2001-10-03 | 2010-11-23 | Novartis Vaccines And Diagnostics, Inc. | Adjuvanted meningococcus compositions |
| AR045702A1 (es) | 2001-10-03 | 2005-11-09 | Chiron Corp | Composiciones de adyuvantes. |
| AU2002334844B2 (en) * | 2001-10-03 | 2007-08-02 | Novartis Vaccines And Diagnostics, Inc. | Adjuvanted meningococcus compositions |
| MX339524B (es) * | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
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| CA2493977A1 (en) | 2002-08-02 | 2004-02-19 | Glaxosmithkline Biologicals Sa | Vaccine composition comprising lipooligosaccharide with reduced phase variability |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
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| EP2351579B1 (en) * | 2002-10-11 | 2016-09-21 | Novartis Vaccines and Diagnostics S.r.l. | Polypeptide vaccines for broad protection against hypervirulent meningococcal lineages |
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| US7807802B2 (en) | 2002-11-12 | 2010-10-05 | Abbott Lab | Polynucleotides for the amplification and detection of Chlamydia trachomatis and Neisseria gonorrhoeae |
| US20070059329A1 (en) | 2002-11-15 | 2007-03-15 | Nathalie Norais | Unexpected surface proteins in meningococcus |
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| EP2263687B1 (en) | 2002-12-27 | 2015-03-25 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions containing phospholipid |
| CN101926988B (zh) | 2003-01-30 | 2014-06-04 | 诺华疫苗和诊断有限公司 | 抗多种脑膜炎球菌血清组的可注射性疫苗 |
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| ES2328697T5 (es) | 2003-06-02 | 2017-07-25 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunogénicas basadas en micropartículas que comprenden toxoide adsorbido y un antígeno que contiene un polisacárido |
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| AU2007281934B2 (en) | 2006-01-18 | 2012-11-15 | University Of Chicago | Compositions and methods related to Staphylococcal bacterium proteins |
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| ATE553774T1 (de) | 2007-10-19 | 2012-05-15 | Novartis Ag | Meningokokkenimpfstoffformulierungen |
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| ES2664753T3 (es) | 2007-12-07 | 2018-04-23 | Glaxosmithkline Biologicals Sa | Composiciones de inducción de respuestas inmunes |
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| HRP20150892T1 (hr) | 2008-03-03 | 2015-09-25 | Novartis Ag | Spojevi i sastavi kao modulatori tlr-aktivnosti |
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| EP2294085A1 (en) * | 2008-06-09 | 2011-03-16 | Novartis AG | Antibodies against neisserial factor h binding protein |
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- 1999-04-30 EP EP05077865A patent/EP1645631B1/en not_active Revoked
- 1999-04-30 EP EP10178545A patent/EP2261355A3/en not_active Withdrawn
- 1999-04-30 CA CA002650642A patent/CA2650642A1/en not_active Expired - Lifetime
- 1999-04-30 ES ES99922752T patent/ES2304065T3/es not_active Expired - Lifetime
- 1999-04-30 EP EP10178521A patent/EP2261344A3/en not_active Withdrawn
- 1999-04-30 EP EP10178510.3A patent/EP2261339B1/en not_active Expired - Lifetime
- 1999-04-30 JP JP2000547235A patent/JP5102414B2/ja not_active Expired - Fee Related
- 1999-04-30 EP EP10178533A patent/EP2261349A3/en not_active Withdrawn
- 1999-04-30 EP EP10178503A patent/EP2261338A3/en not_active Withdrawn
- 1999-04-30 DK DK99922752T patent/DK1093517T3/da active
- 1999-04-30 EP EP10178538A patent/EP2261352A3/en not_active Withdrawn
- 1999-04-30 MX MX2013011115A patent/MX343744B/es unknown
- 1999-04-30 EP EP10178537A patent/EP2261351A3/en not_active Withdrawn
- 1999-04-30 EP EP10178535A patent/EP2261350A3/en not_active Withdrawn
- 1999-04-30 NZ NZ527182A patent/NZ527182A/xx not_active IP Right Cessation
- 1999-04-30 EP EP10178516A patent/EP2261341A3/en not_active Withdrawn
- 1999-04-30 EP EP99922752A patent/EP1093517B1/en not_active Expired - Lifetime
- 1999-04-30 NZ NZ508366A patent/NZ508366A/xx not_active IP Right Cessation
- 1999-04-30 EP EP10178520A patent/EP2261343A3/en not_active Withdrawn
- 1999-04-30 EP EP10178529A patent/EP2261346A3/en not_active Withdrawn
- 1999-04-30 EP EP10178543A patent/EP2261354A3/en not_active Withdrawn
- 1999-04-30 EP EP10178530A patent/EP2261347A3/en not_active Withdrawn
- 1999-04-30 WO PCT/US1999/009346 patent/WO1999057280A2/en not_active Ceased
- 1999-04-30 AT AT99922752T patent/ATE388230T1/de active
- 1999-04-30 MX MX2013012066A patent/MX339406B/es unknown
- 1999-04-30 BR BR9910089-4A patent/BR9910089A/pt not_active Application Discontinuation
- 1999-04-30 EP EP10178522A patent/EP2261345A3/en not_active Withdrawn
- 1999-04-30 DE DE69937419T patent/DE69937419T2/de not_active Expired - Lifetime
- 1999-04-30 AU AU39677/99A patent/AU761780B2/en not_active Ceased
- 1999-04-30 EP EP10179752A patent/EP2261357A3/en not_active Withdrawn
- 1999-04-30 MX MX2014014862A patent/MX343752B/es unknown
- 1999-04-30 EP EP10178532A patent/EP2261348A3/en not_active Withdrawn
- 1999-04-30 NZ NZ532665A patent/NZ532665A/xx not_active IP Right Cessation
- 1999-04-30 MX MXPA00010722A patent/MXPA00010722A/es not_active IP Right Cessation
- 1999-04-30 ES ES05077865T patent/ES2294629T3/es not_active Expired - Lifetime
- 1999-04-30 DE DE69938302T patent/DE69938302T2/de not_active Expired - Lifetime
- 1999-04-30 US US09/674,546 patent/US7576176B1/en not_active Expired - Fee Related
- 1999-04-30 CN CNB998081450A patent/CN1210305C/zh not_active Expired - Fee Related
- 1999-04-30 EP EP10179068A patent/EP2261356A3/en not_active Withdrawn
- 1999-04-30 DK DK05077865T patent/DK1645631T3/da active
- 1999-04-30 PT PT05077865T patent/PT1645631E/pt unknown
- 1999-04-30 AT AT05077865T patent/ATE376591T1/de active
- 1999-04-30 NZ NZ541361A patent/NZ541361A/en not_active IP Right Cessation
- 1999-04-30 EP EP10178542A patent/EP2261353A3/en not_active Withdrawn
- 1999-04-30 EP EP10178517A patent/EP2261342A3/en not_active Withdrawn
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2008
- 2008-01-11 US US12/013,047 patent/US7988979B2/en not_active Expired - Fee Related
- 2008-01-17 CY CY20081100066T patent/CY1109649T1/el unknown
- 2008-05-30 CY CY20081100564T patent/CY1108083T1/el unknown
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2009
- 2009-05-25 JP JP2009125889A patent/JP2009183306A/ja not_active Withdrawn
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2010
- 2010-02-16 JP JP2010031866A patent/JP2010166916A/ja not_active Withdrawn
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2011
- 2011-03-23 US US13/070,448 patent/US9139621B2/en not_active Expired - Fee Related
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2012
- 2012-01-26 US US13/359,459 patent/US20120156236A1/en not_active Abandoned
- 2012-01-26 US US13/359,471 patent/US8524251B2/en not_active Expired - Fee Related
- 2012-01-26 US US13/359,442 patent/US9249196B2/en not_active Expired - Fee Related
- 2012-06-21 JP JP2012140207A patent/JP2012191945A/ja active Pending
- 2012-06-21 JP JP2012140208A patent/JP2012191946A/ja not_active Withdrawn
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2013
- 2013-07-30 JP JP2013157834A patent/JP6025674B2/ja not_active Expired - Lifetime
- 2013-07-30 JP JP2013157835A patent/JP6025675B2/ja not_active Expired - Lifetime
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2014
- 2014-08-01 US US14/450,075 patent/US9266929B2/en not_active Expired - Fee Related
- 2014-08-01 US US14/450,082 patent/US9249198B2/en not_active Expired - Fee Related
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2015
- 2015-07-21 US US14/804,756 patent/US20160030545A1/en not_active Abandoned
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2016
- 2016-08-05 JP JP2016154472A patent/JP2016222709A/ja not_active Withdrawn
- 2016-09-30 JP JP2016192774A patent/JP2017012195A/ja not_active Withdrawn