JP2012000112A5 - - Google Patents
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- JP2012000112A5 JP2012000112A5 JP2011166505A JP2011166505A JP2012000112A5 JP 2012000112 A5 JP2012000112 A5 JP 2012000112A5 JP 2011166505 A JP2011166505 A JP 2011166505A JP 2011166505 A JP2011166505 A JP 2011166505A JP 2012000112 A5 JP2012000112 A5 JP 2012000112A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- nucleic acid
- seq
- sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 206010035664 Pneumonia Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 206010053555 Arthritis bacterial Diseases 0.000 claims 1
- 208000031729 Bacteremia Diseases 0.000 claims 1
- 206010007882 Cellulitis Diseases 0.000 claims 1
- 206010010741 Conjunctivitis Diseases 0.000 claims 1
- 206010014568 Empyema Diseases 0.000 claims 1
- 201000009906 Meningitis Diseases 0.000 claims 1
- 206010031252 Osteomyelitis Diseases 0.000 claims 1
- 206010033078 Otitis media Diseases 0.000 claims 1
- 210000001744 T-lymphocyte Anatomy 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 206010006451 bronchitis Diseases 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000001606 epiglottitis Diseases 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000008494 pericarditis Diseases 0.000 claims 1
- 201000009890 sinusitis Diseases 0.000 claims 1
- 208000019206 urinary tract infection Diseases 0.000 claims 1
- 239000012646 vaccine adjuvant Substances 0.000 claims 1
- 229940124931 vaccine adjuvant Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0410866.8 | 2004-05-14 | ||
| GBGB0410866.8A GB0410866D0 (en) | 2004-05-14 | 2004-05-14 | Haemophilius influenzae |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Division JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012000112A JP2012000112A (ja) | 2012-01-05 |
| JP2012000112A5 true JP2012000112A5 (enExample) | 2012-04-05 |
Family
ID=32527109
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Withdrawn JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
| JP2011166505A Pending JP2012000112A (ja) | 2004-05-14 | 2011-07-29 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007512595A Withdrawn JP2008506364A (ja) | 2004-05-14 | 2005-05-16 | 型分類不能なＨａｅｍｏｐｈｉｌｕｓｉｎｆｌｕｅｎｚａｅ由来のポリペプチド |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7749518B2 (enExample) |
| EP (5) | EP2343313A1 (enExample) |
| JP (2) | JP2008506364A (enExample) |
| CN (1) | CN1997663A (enExample) |
| BR (1) | BRPI0511118A (enExample) |
| CA (1) | CA2566632A1 (enExample) |
| GB (1) | GB0410866D0 (enExample) |
| IN (1) | IN2015KN00290A (enExample) |
| RU (1) | RU2432357C2 (enExample) |
| WO (1) | WO2005111066A2 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02008313A (es) * | 2000-02-28 | 2002-12-09 | Chiron Spa | Expresion hibrida de proteinas de neisseria. |
| US8663656B2 (en) * | 2002-10-11 | 2014-03-04 | Novartis Ag | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| JP2008538183A (ja) * | 2005-03-30 | 2008-10-16 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | Ｂ型インフルエンザ菌 |
| JP2008546390A (ja) | 2005-06-16 | 2008-12-25 | ネイションワイド チルドレンズ ホスピタル， インコーポレイテッド | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| EP2548885B1 (en) | 2005-08-10 | 2017-10-18 | Arne Forsgren AB | Interaction of moraxella catarrhalis with epithelial cells, extracellular matrix proteins and the complement system |
| EA015561B1 (ru) * | 2006-01-17 | 2011-08-30 | Арне Форсгрен | НОВЫЙ ПОВЕРХНОСТНЫЙ БЕЛОК HAEMOPHILUS INFLUENZAE (БЕЛОК E; pE) |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| CA2747340A1 (en) * | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
| US8617574B2 (en) * | 2009-02-13 | 2013-12-31 | Valneva Austria Gmbh | Nontypable Haemophilus influenzae antigens |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| PL2591114T3 (pl) | 2010-07-06 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Immunizacja dużych ssaków małymi dawkami rna |
| EP2590676B1 (en) | 2010-07-06 | 2016-08-17 | GlaxoSmithKline Biologicals SA | Virion-like delivery particles for self-replicating rna molecules |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| SI3243526T1 (sl) | 2010-07-06 | 2020-02-28 | Glaxosmithkline Biologicals S.A. | Dostava RNA za sprožitev večih imunskih poti |
| HUE026646T2 (en) | 2010-07-06 | 2016-07-28 | Glaxosmithkline Biologicals Sa | Preferred liposomes containing lipids of PKA value for delivery of RNA |
| RS63329B1 (sr) | 2010-08-31 | 2022-07-29 | Glaxosmithkline Biologicals Sa | Pegilovani lipozomi za isporuku rnk koja kodira imunogen |
| AU2011295938B2 (en) | 2010-08-31 | 2016-01-14 | Glaxosmithkline Biologicals S.A. | Lipids suitable for liposomal delivery of protein-coding RNA |
| CN103269713B (zh) | 2010-10-11 | 2016-01-20 | 诺华有限公司 | 抗原递送平台 |
| TW201302779A (zh) | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| BR112013029024A2 (pt) * | 2011-05-11 | 2017-10-31 | Riesbeck Healthcare Sweden Ab | proteína f - uma nova adesina de haemophilus influenzae com propriedades de ligação à laminina e vitronectina |
| EP3332802A1 (en) | 2011-07-06 | 2018-06-13 | GlaxoSmithKline Biologicals SA | Immunogenic combination compositions and uses thereof |
| JP2014520806A (ja) | 2011-07-06 | 2014-08-25 | ノバルティス アーゲー | Ｒｎａ分子の送達のための有用なｎ：ｐ比を有するリポソーム |
| HUE041800T2 (hu) | 2011-08-31 | 2019-05-28 | Glaxosmithkline Biologicals Sa | Pegilált liposzómák immunogént kódoló RNS bejuttatására |
| CN104321078A (zh) | 2012-04-26 | 2015-01-28 | 诺华股份有限公司 | 抗原和抗原组合 |
| US10279026B2 (en) * | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| CN104602702B (zh) | 2012-09-18 | 2021-08-27 | 葛兰素史密丝克莱恩生物有限公司 | 外膜囊泡 |
| MX377255B (es) | 2013-03-08 | 2025-03-07 | Novartis Ag | Lipidos y composiciones de lipidos para el suministro de agentes activos. |
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| WO2015095346A1 (en) | 2013-12-19 | 2015-06-25 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
| JP6778175B2 (ja) | 2014-07-16 | 2020-10-28 | ノバルティス アーゲー | 脂質ナノ粒子ホスト中に核酸を封入する方法 |
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| CN107072946B (zh) | 2014-09-05 | 2022-01-11 | 诺华股份有限公司 | 用于递送活性剂的脂质和脂质组合物 |
| EP3061826A1 (en) | 2015-02-27 | 2016-08-31 | Novartis AG | Flavivirus replicons |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
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| EP3322408B1 (en) | 2015-07-14 | 2022-06-08 | The Research Institute at Nationwide Children's Hospital | Novel formulation for the elimination of cariogenic and opportunistic pathogens within the oral cavity |
| WO2017023863A1 (en) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides and antibodies for the removal of biofilms |
| EP3365027B1 (en) | 2015-10-14 | 2022-03-30 | Research Institute at Nationwide Children's Hospital | Hu specific antibodies and their use in inhibiting biofilm |
| EP3450446A4 (en) * | 2016-04-27 | 2019-03-06 | Biocells (Beijing) Biotech Co., Ltd. | METHOD OF TREATING ADVERSE NEUROTOXICITY-RELATED INJURIES |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3565834B1 (en) * | 2017-01-04 | 2025-10-22 | The Research Institute at Nationwide Children's Hospital | Antibody fragments for the treatment of biofilm-related disorders |
| JP7514621B2 (ja) | 2017-01-04 | 2024-07-11 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | Ｄｎａｂｉｉワクチンおよび強化された活性を有する抗体 |
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| WO2018170178A1 (en) | 2017-03-15 | 2018-09-20 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| WO2020072993A1 (en) | 2018-10-05 | 2020-04-09 | Research Institute At Nationwide Children's Hospital | Hmgb1 protein derivatives for the removal of biofilms cross-reference to related application |
| WO2020174044A1 (en) * | 2019-02-27 | 2020-09-03 | Evaxion Biotech Aps | Vaccines targeting h. influenzae |
| WO2021007260A2 (en) | 2019-07-08 | 2021-01-14 | Research Institute At Nationwide Children's Hospital | Antibody compositions for disrupting biofilms |
| AU2021228218A1 (en) | 2020-02-28 | 2022-09-01 | Trait Biosciences, Inc. | Novel systems, methods, and compositions for the glycosylation of cannabinoid compounds |
| US12116614B2 (en) | 2020-06-30 | 2024-10-15 | Research Institute At Nationwide Children's Hospital | Methods for determining antibiotic sensitivity |
| TW202229228A (zh) | 2020-10-14 | 2022-08-01 | 喬治梅森研究基金會 | 可離子化脂質及其製造和使用方法 |
| CN115678869B (zh) * | 2021-07-28 | 2025-08-29 | 梅花(上海)生物科技有限公司 | 一株重组菌株及其生产氨基酸的方法 |
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| US20250134824A1 (en) | 2021-08-16 | 2025-05-01 | Glaxosmithkline Biologicals Sa | Low-dose lyophilized rna vaccines and methods for preparing and using the same |
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| WO2003076575A2 (en) * | 2002-03-04 | 2003-09-18 | Fidelity Systems, Inc., Et Al. | The complete genome and protein sequence of the hyperthermophile methanopyrus kandleri av19 and monophyly of archael methanogens and methods of use thereof |
| CA2517899A1 (en) | 2003-03-06 | 2004-09-16 | Children's Hospital, Inc. | Genes of an otitis media isolate of nontypeable haemophilus influenzae |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| JP2008546390A (ja) | 2005-06-16 | 2008-12-25 | ネイションワイド チルドレンズ ホスピタル， インコーポレイテッド | 分類不能型インフルエンザ菌の中耳炎単離物の遺伝子 |
| EA015561B1 (ru) | 2006-01-17 | 2011-08-30 | Арне Форсгрен | НОВЫЙ ПОВЕРХНОСТНЫЙ БЕЛОК HAEMOPHILUS INFLUENZAE (БЕЛОК E; pE) |
| AT507928B1 (de) | 2008-06-30 | 2015-09-15 | Coil Holding Gmbh | Drosselspule für elektrische energieversorgungsnetze mit reduzierten schallemissionen |
| US9018858B2 (en) | 2008-09-24 | 2015-04-28 | B/E Aerospace, Inc. | Calibration method for LED lighting systems |
-
2004
- 2004-05-14 GB GBGB0410866.8A patent/GB0410866D0/en not_active Ceased
-
2005
- 2005-05-16 CA CA002566632A patent/CA2566632A1/en not_active Abandoned
- 2005-05-16 WO PCT/IB2005/001775 patent/WO2005111066A2/en not_active Ceased
- 2005-05-16 IN IN290KON2015 patent/IN2015KN00290A/en unknown
- 2005-05-16 EP EP10194789A patent/EP2343313A1/en not_active Withdrawn
- 2005-05-16 EP EP10190381A patent/EP2351773A1/en not_active Withdrawn
- 2005-05-16 CN CNA2005800238288A patent/CN1997663A/zh active Pending
- 2005-05-16 US US11/596,557 patent/US7749518B2/en not_active Expired - Fee Related
- 2005-05-16 EP EP10190386A patent/EP2341069A1/en not_active Withdrawn
- 2005-05-16 EP EP10190390A patent/EP2351774A1/en not_active Withdrawn
- 2005-05-16 RU RU2006144093/10A patent/RU2432357C2/ru not_active IP Right Cessation
- 2005-05-16 EP EP05748150A patent/EP1745067A2/en not_active Withdrawn
- 2005-05-16 JP JP2007512595A patent/JP2008506364A/ja not_active Withdrawn
- 2005-05-16 BR BRPI0511118-8A patent/BRPI0511118A/pt not_active Application Discontinuation
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2010
- 2010-05-25 US US12/800,898 patent/US8124098B2/en not_active Expired - Fee Related
-
2011
- 2011-07-29 JP JP2011166505A patent/JP2012000112A/ja active Pending
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2012
- 2012-01-24 US US13/357,394 patent/US20120148615A1/en not_active Abandoned
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2014
- 2014-04-29 US US14/264,972 patent/US9102729B2/en not_active Expired - Fee Related
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