GB9713156D0 - Vaccines - Google Patents

Vaccines

Info

Publication number
GB9713156D0
GB9713156D0 GBGB9713156.9A GB9713156A GB9713156D0 GB 9713156 D0 GB9713156 D0 GB 9713156D0 GB 9713156 A GB9713156 A GB 9713156A GB 9713156 D0 GB9713156 D0 GB 9713156D0
Authority
GB
United Kingdom
Prior art keywords
pertussis
fimbria
conjugate
antigen
vaccinating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GBGB9713156.9A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbiological Research Authority
Original Assignee
Microbiological Research Authority
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbiological Research Authority filed Critical Microbiological Research Authority
Priority to GBGB9713156.9A priority Critical patent/GB9713156D0/en
Publication of GB9713156D0 publication Critical patent/GB9713156D0/en
Application status is Pending legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/381Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus
    • Y02A50/384Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus
    • Y02A50/385Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Dengue
    • Y02A50/386Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Dengue the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/381Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus
    • Y02A50/384Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus
    • Y02A50/389Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Japanese encephalitis
    • Y02A50/39Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Japanese encephalitis the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/381Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus
    • Y02A50/384Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus
    • Y02A50/395Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Tick-borne encephalitis [TBE]
    • Y02A50/396Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a virus of the genus Flavivirus the disease being Tick-borne encephalitis [TBE] the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/398Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a bacteria
    • Y02A50/402Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a bacteria of the genus Rickettsia, Orientia, Ehrlichia, Neorickettsia, Neoehrlichia or Anaplasma, i.e. Rickettsial diseases, e.g. spotted fever
    • Y02A50/406Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a bacteria of the genus Rickettsia, Orientia, Ehrlichia, Neorickettsia, Neoehrlichia or Anaplasma, i.e. Rickettsial diseases, e.g. spotted fever the bacteria being Yersinia pestis, i.e. Plague
    • Y02A50/407Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a bacteria of the genus Rickettsia, Orientia, Ehrlichia, Neorickettsia, Neoehrlichia or Anaplasma, i.e. Rickettsial diseases, e.g. spotted fever the bacteria being Yersinia pestis, i.e. Plague the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/38Medical treatment of vector-borne diseases characterised by the agent
    • Y02A50/408Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a protozoa
    • Y02A50/411Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a protozoa of the genus Plasmodium, i.e. Malaria
    • Y02A50/412Medical treatment of vector-borne diseases characterised by the agent the vector-borne disease being caused by a protozoa of the genus Plasmodium, i.e. Malaria the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y02A50/46Medical treatment of waterborne diseases characterized by the agent
    • Y02A50/462The waterborne disease being caused by a virus
    • Y02A50/465The waterborne disease being caused by a virus the virus being the poliovirus, i.e. Poliomyelitis or Polio
    • Y02A50/466The waterborne disease being caused by a virus the virus being the poliovirus, i.e. Poliomyelitis or Polio the medicinal preparation containing antigens or antibodies, e.g. vaccines, antisera

Abstract

A vaccinating conjugate comprises an antigen conjugated to a carrier selected from Bordetella pertussis fimbria, pertussis toxin, pertussis toxoid, and pertussis 69kD protein. The conjugate may also comprise a second antigen, different from the first. An oral vaccinating composition comprises Bordetella pertussis fimbria or fimbria-antigen conjugate.
GBGB9713156.9A 1997-06-20 1997-06-20 Vaccines Pending GB9713156D0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GBGB9713156.9A GB9713156D0 (en) 1997-06-20 1997-06-20 Vaccines

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9713156.9A GB9713156D0 (en) 1997-06-20 1997-06-20 Vaccines
JP50400699A JP2002508761A (en) 1997-06-20 1998-06-22 Bordetella pertussis antigen as carrier in vaccinated conjugates and oral vaccine containing Bordetella pertussis fimbriae
AU81194/98A AU731216B2 (en) 1997-06-20 1998-06-22 Vaccines containing bordetella pertussis antigen
PCT/GB1998/001819 WO1998058668A2 (en) 1997-06-20 1998-06-22 Bordetella pertussis antigens as carriers in vaccinating conjugates and oral vaccines comprising bordetella pertussis fimbriae
EP98930917A EP1005367A2 (en) 1997-06-20 1998-06-22 Vaccines containing bordetella pertussis antigen
CA002294348A CA2294348A1 (en) 1997-06-20 1998-06-22 Vaccines containing bordetella pertussis antigen

Publications (1)

Publication Number Publication Date
GB9713156D0 true GB9713156D0 (en) 1997-08-27

Family

ID=10814739

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9713156.9A Pending GB9713156D0 (en) 1997-06-20 1997-06-20 Vaccines

Country Status (6)

Country Link
EP (1) EP1005367A2 (en)
JP (1) JP2002508761A (en)
AU (1) AU731216B2 (en)
CA (1) CA2294348A1 (en)
GB (1) GB9713156D0 (en)
WO (1) WO1998058668A2 (en)

Families Citing this family (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT355375T (en) 1996-01-04 2006-03-15 Novartis Vaccines & Diagnostic Bacterioferritine from helicobacter pylori
AU5441199A (en) * 1998-09-01 2000-03-21 Elan Corporation, Plc Oral vaccine compositions
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
AT322285T (en) * 1998-09-01 2006-04-15 Elan Corp Plc Method for the induction of the cellular immune response and parenteral vaccine compositions therefor
GB0018031D0 (en) * 2000-07-21 2000-09-13 Microbiological Res Authority Improvements relating to vaccines containing bordetella pertussis antigen
EP2277894A1 (en) 2000-10-27 2011-01-26 Novartis Vaccines and Diagnostics S.r.l. Nucleic acids and proteins from streptococcus groups A & B
US7082569B2 (en) 2001-01-17 2006-07-25 Outlooksoft Corporation Systems and methods providing dynamic spreadsheet functionality
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
DE60228758D1 (en) 2001-12-12 2008-10-16 Novartis Vaccines & Diagnostic Immunization against chlamydia tracheomatis
EP1531796B1 (en) 2002-02-20 2016-09-28 GlaxoSmithKline Biologicals SA Microparticles with adsorbed polypeptide-containing molecules
DE60328481D1 (en) 2002-05-14 2009-09-03 Novartis Vaccines & Diagnostic Sleep-capacitive vaccine containing the adjuvanz chitosan and menigokokkenantigene
CN1816350B (en) * 2002-05-14 2010-11-10 莱顿大学;启龙有限公司 Mucosal vaccines with chitosan adjuvant and/or meningococcal antigens
GB0220194D0 (en) 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CA2501812C (en) 2002-10-11 2012-07-10 Mariagrazia Pizza Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
CA2503946C (en) 2002-11-01 2016-08-16 Glaxosmithkline Biologicals S.A. Drying process
PT2279746E (en) 2002-11-15 2013-12-09 Novartis Vaccines & Diagnostic Surface proteins in neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
US8034378B2 (en) 2002-12-27 2011-10-11 Novartis Vaccines And Diagnostics, Inc Immunogenic compositions containing phospholipid
GB0302218D0 (en) 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
US10272147B2 (en) 2003-01-30 2019-04-30 Glaxosmithkline Biologicals S.A. Injectable vaccines against multiple meningococcal serogroups
ES2423800T3 (en) 2003-03-28 2013-09-24 Novartis Vaccines And Diagnostics, Inc. Use of organic compounds for immunopotentiation
EP1631264B8 (en) 2003-06-02 2017-05-24 GlaxoSmithKline Biologicals SA Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
EP1670506B1 (en) 2003-10-02 2012-11-21 Novartis AG Liquid vaccines for multiple meningococcal serogroups
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0406013D0 (en) 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
GB0408978D0 (en) 2004-04-22 2004-05-26 Chiron Srl Meningococcal fermentation for preparing conjugate vaccines
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
GB0410866D0 (en) 2004-05-14 2004-06-16 Chiron Srl Haemophilius influenzae
GB0411387D0 (en) 2004-05-21 2004-06-23 Chiron Srl Analysis of saccharide length
GB0413868D0 (en) 2004-06-21 2004-07-21 Chiron Srl Dimensional anlaysis of saccharide conjugates
EP2277595A3 (en) 2004-06-24 2011-09-28 Novartis Vaccines and Diagnostics, Inc. Compounds for immunopotentiation
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP2612679A1 (en) 2004-07-29 2013-07-10 Novartis Vaccines and Diagnostics, Inc. Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
GB0424092D0 (en) 2004-10-29 2004-12-01 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
WO2006091517A2 (en) 2005-02-18 2006-08-31 Novartis Vaccines And Diagnostics Inc. Immunogens from uropathogenic escherichia coli
DK2351772T3 (en) 2005-02-18 2016-09-05 Glaxosmithkline Biologicals Sa Proteins and nucleic acids from meningitis / sepsis-associated Escherichia coli
EP2329843A3 (en) 2005-04-18 2011-09-14 Novartis Vaccines and Diagnostics, Inc. Expressing Hepatitis B Virus surface antigen for vaccine preparation
CA2611964C (en) 2005-06-27 2016-11-08 Glaxosmithkline Biologicals S.A. Process for manufacturing vaccines
EP1931380A2 (en) 2005-09-01 2008-06-18 Novartis Vaccines and Diagnostics GmbH & Co. KG Multiple vaccination including serogroup c meningococcus
GB0522765D0 (en) 2005-11-08 2005-12-14 Chiron Srl Combination vaccine manufacture
JP5215865B2 (en) 2005-11-22 2013-06-19 ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド Norovirus and sapovirus antigens
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
HUE041979T2 (en) 2005-12-22 2019-06-28 Glaxosmithkline Biologicals Sa Pneumococcal polysaccharide conjugate vaccine
ES2383209T3 (en) 2006-03-22 2012-06-19 Novartis Ag Regimens for immunization with meningococcal conjugates
GB0605757D0 (en) 2006-03-22 2006-05-03 Chiron Srl Separation of conjugated and unconjugated components
ES2376492T3 (en) 2006-03-23 2012-03-14 Novartis Ag Imidazoquinoxaline compounds as immunomodulators.
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
PL2054431T3 (en) 2006-06-09 2012-07-31 Novartis Ag Conformers of bacterial adhesins
GB0612854D0 (en) 2006-06-28 2006-08-09 Novartis Ag Saccharide analysis
EP2586790A3 (en) 2006-08-16 2013-08-14 Novartis AG Immunogens from uropathogenic Escherichia coli
WO2008028956A1 (en) 2006-09-07 2008-03-13 Glaxosmithkline Biologicals S.A. Vaccine
GB0700136D0 (en) 2007-01-04 2007-02-14 Glaxosmithkline Biolog Sa Process for manufacturing vaccines
GB0700562D0 (en) 2007-01-11 2007-02-21 Novartis Vaccines & Diagnostic Modified Saccharides
PE20090212A1 (en) 2007-05-02 2009-03-30 Glaxosmithkline Biolog Sa Kit vaccine for primary immunization
CA2690707A1 (en) 2007-06-26 2008-12-31 Glaxosmithkline Biologicals S.A. A vaccine for treatment or prevention of a disease caused by streptococcus pneumoniae
GB0713880D0 (en) 2007-07-17 2007-08-29 Novartis Ag Conjugate purification
GB0714963D0 (en) 2007-08-01 2007-09-12 Novartis Ag Compositions comprising antigens
US8287885B2 (en) 2007-09-12 2012-10-16 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
US20100285069A1 (en) 2007-10-19 2010-11-11 Mario Contorni Meningococcal vaccine formulations
CA2709927C (en) 2007-12-21 2017-05-16 Novartis Ag Mutant forms of streptolysin o
BRPI0907843A2 (en) 2008-02-21 2015-08-04 Novartis Ag Menigococcal fhbp polypeptides
GB0818453D0 (en) 2008-10-08 2008-11-12 Novartis Ag Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom
PL2349520T3 (en) 2008-10-27 2017-08-31 Glaxosmithkline Biologicals Sa Purification method for carbohydrate from group a streptococcus
GB0822633D0 (en) 2008-12-11 2009-01-21 Novartis Ag Formulation
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
US8585505B2 (en) 2008-12-15 2013-11-19 Tetris Online, Inc. Inter-game interactive hybrid asynchronous computer game infrastructure
CA2747340A1 (en) 2008-12-17 2010-06-24 Novartis Ag Meningococcal vaccines including hemoglobin receptor
CN102307477B (en) 2009-01-05 2015-07-29 埃皮托吉尼西斯股份有限公司 Adjunvant composition and using method
US8465751B2 (en) 2009-01-12 2013-06-18 Novartis Ag Cna—B domain antigens in vaccines against gram positive bacteria
CN102438649A (en) 2009-03-24 2012-05-02 诺华有限公司 Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
RU2557315C2 (en) 2009-03-24 2015-07-20 Новартис Аг Factor h-binding adjuvant meningococcal protein
SG10201404076TA (en) 2009-04-14 2014-10-30 Novartis Ag Compositions for immunising against staphylococcus aureus
WO2010125480A1 (en) 2009-04-30 2010-11-04 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2010132833A1 (en) 2009-05-14 2010-11-18 The Regents Of The University Of Michigan Streptococcus vaccine compositions and methods of using the same
EP2470204B1 (en) 2009-08-27 2015-12-16 GlaxoSmithKline Biologicals SA Hybrid polypeptides including meningococcal fhbp sequences
MX2012002639A (en) 2009-09-03 2012-03-14 Pfizer Vaccines Llc Pcsk9 vaccine.
CN102695523A (en) 2009-09-10 2012-09-26 诺华有限公司 Combination vaccines against respiratory tract diseases
WO2011138636A1 (en) 2009-09-30 2011-11-10 Novartis Ag Conjugation of staphylococcus aureus type 5 and type 8 capsular polysaccharides
AU2010302344A1 (en) 2009-09-30 2012-04-26 Novartis Ag Expression of meningococcal fhbp polypeptides
JP5960055B2 (en) 2009-10-27 2016-08-02 ノバルティス アーゲー Modified meningococcal fHBP polypeptide
HUE034251T2 (en) 2009-10-30 2018-02-28 Glaxosmithkline Biologicals Sa Purification of staphylococcus aureus type 5 and type 8 capsular saccharides
GB0919690D0 (en) 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
GB201003333D0 (en) 2010-02-26 2010-04-14 Novartis Ag Immunogenic proteins and compositions
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201005625D0 (en) 2010-04-01 2010-05-19 Novartis Ag Immunogenic proteins and compositions
CA2803239A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
WO2012072769A1 (en) 2010-12-01 2012-06-07 Novartis Ag Pneumococcal rrgb epitopes and clade combinations
CA2860331A1 (en) 2010-12-24 2012-06-28 Novartis Ag Compounds
ES2612511T3 (en) 2011-01-27 2017-05-17 Glaxosmithkline Biologicals Sa Adjuvant nanoemulsions with crystallization inhibitors
GB201101665D0 (en) 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions
EP2680883B1 (en) 2011-03-02 2018-09-05 Pfizer Inc Pcsk9 vaccine
WO2012117377A1 (en) 2011-03-02 2012-09-07 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
WO2012129483A1 (en) 2011-03-24 2012-09-27 Novartis Ag Adjuvant nanoemulsions with phospholipids
EP2511295A1 (en) 2011-04-15 2012-10-17 Institut National De La Sante Et De La Recherche Medicale Compositions for preventing and/or treating an infection by an HIV-1 virus
JP6088507B2 (en) 2011-07-08 2017-03-01 ノバルティス アーゲー Tyrosine ligation method
GB201114923D0 (en) 2011-08-30 2011-10-12 Novartis Ag Immunogenic proteins and compositions
ES2732708T3 (en) 2011-09-14 2019-11-25 Glaxosmithkline Biologicals Sa Manufacturing procedures of saccharide-protein glucoconjugates
CN104080479B (en) 2011-11-07 2019-11-05 葛兰素史密丝克莱恩生物有限公司 Carrier molecules including spr0096 and spr2021 antigen
DE102011122891B4 (en) 2011-11-11 2014-12-24 Novartis Ag Fermentation medium, which is free of animal components, for the preparation of diphtheria toxoids for use in the vaccination of humans
EP2592137A1 (en) 2011-11-11 2013-05-15 Novartis AG Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use
DE102011118371B4 (en) 2011-11-11 2014-02-13 Novartis Ag Composition suitable for human vaccination, comprising a diphtheria toxoid, and process for its preparation
GB2495341B (en) 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
CA2858519A1 (en) 2011-12-08 2013-06-13 Novartis Ag Clostridium difficile toxin-based vaccine
GB201121301D0 (en) 2011-12-12 2012-01-25 Novartis Ag Method
JP2015505309A (en) 2011-12-29 2015-02-19 ノバルティス アーゲー Adjuvanted combination of meningococcal factor H binding protein
RU2014138418A (en) 2012-02-24 2016-04-10 Новартис Аг Proteins of saws and compositions
JP2015510872A (en) 2012-03-07 2015-04-13 ノバルティス アーゲー Enhanced formulation of Streptococcus pneumoniae antigen
JP2015509963A (en) 2012-03-08 2015-04-02 ノバルティス アーゲー Combination vaccine containing a TLR4 agonist
US10279026B2 (en) 2012-04-26 2019-05-07 Glaxosmithkline Biologicals Sa Antigens and antigen combinations
CN108671228A (en) 2012-04-26 2018-10-19 诺华股份有限公司 antigen and antigen combination
WO2013174832A1 (en) 2012-05-22 2013-11-28 Novartis Ag Meningococcus serogroup x conjugate
RU2015106930A (en) 2012-09-06 2016-10-20 Новартис Аг Combined vaccines with the meningococc serograph b and k / d / s
MX2015002482A (en) 2012-10-03 2016-01-08 Glaxosmithkline Biolog Sa Immunogenic composition.
JP6440619B2 (en) 2012-10-12 2018-12-19 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Uncrosslinked acellular pertussis antigen for combination vaccines
AU2013351182C1 (en) 2012-11-30 2018-11-08 Glaxosmithkline Biologicals Sa Pseudomonas antigens and antigen combinations
JP6411378B2 (en) 2013-02-01 2018-10-24 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Intradermal delivery of an immunological composition comprising a TOLL-like receptor agonist
KR20150124973A (en) * 2013-03-08 2015-11-06 크루셀 홀란드 비.브이. Acellular pertussis vaccine
AU2015208822A1 (en) 2014-01-21 2016-07-21 Pfizer Inc. Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
PE20161095A1 (en) 2014-01-21 2016-10-26 Pfizer immunogenic compositions comprising capsular saccharide antigens conjugated and use thereof
KR20190132580A (en) 2014-01-21 2019-11-27 화이자 인코포레이티드 Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
US20170007713A1 (en) 2014-02-14 2017-01-12 Pfizer Inc. Immunogenic glycoprotein conjugates
EP3034516A1 (en) 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
WO2016113644A1 (en) 2015-01-15 2016-07-21 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
WO2016184963A1 (en) 2015-05-19 2016-11-24 Innavirvax Treatment of hiv-infected individuals
WO2016184962A1 (en) 2015-05-19 2016-11-24 Innavirvax Treatment of hiv-infected individuals
EP3109255A1 (en) 2015-06-26 2016-12-28 Institut National De La Recherche Agronomique Immunogenic composition
BR112018000087A2 (en) 2015-07-21 2018-09-04 Pfizer immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising them and uses thereof
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
CA3005524A1 (en) 2015-11-20 2017-05-26 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
WO2017175082A1 (en) 2016-04-05 2017-10-12 Gsk Vaccines S.R.L. Immunogenic compositions
EP3506933A2 (en) 2016-09-02 2019-07-10 GlaxoSmithKline Biologicals SA Vaccines for neisseria gonorrhoeae
US20190388532A1 (en) 2016-10-07 2019-12-26 Enterome S.A. Immunogenic Compounds For Cancer Therapy
AU2017339577A1 (en) 2016-10-07 2019-05-02 Enterome S.A. Immunogenic compounds for cancer therapy
EP3551668A1 (en) 2016-12-06 2019-10-16 GlaxoSmithKline Biologicals S.A. Purification process for capsular polysaccharide
KR20190097176A (en) 2017-01-20 2019-08-20 화이자 인코포레이티드 Immunogenic Compositions for Use in Pneumococcal Vaccines
US10183070B2 (en) 2017-01-31 2019-01-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
WO2019139692A2 (en) 2017-12-06 2019-07-18 Merck Sharp & Dohme Corp. Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
WO2019197567A2 (en) 2018-04-11 2019-10-17 Enterome S.A. Antigenic peptides for prevention and treatment of cancer
WO2019197563A2 (en) 2018-04-11 2019-10-17 Enterome S.A. Immunogenic compounds for treatment of fibrosis, autoimmune diseases and inflammation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634153B2 (en) * 1988-02-01 1993-02-18 Wyeth Holdings Corporation T-cell epitope as carriers molecule for conjugate vaccines
US5101014A (en) * 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis
IT1248735B (en) * 1990-06-21 1995-01-26 Sclavo Spa Acellular pertussis
DE69231663T2 (en) * 1991-03-12 2001-08-23 Nasa Polysaccharide-protein conjugate
DE69331495T2 (en) * 1992-08-31 2002-10-31 Baxter Healthcare Sa Vaccines against Neisseria meningitidis group C

Also Published As

Publication number Publication date
JP2002508761A (en) 2002-03-19
AU731216B2 (en) 2001-03-29
CA2294348A1 (en) 1998-12-30
WO1998058668A2 (en) 1998-12-30
WO1998058668A3 (en) 1999-04-15
AU8119498A (en) 1999-01-04
EP1005367A2 (en) 2000-06-07

Similar Documents

Publication Publication Date Title
RU2221809C2 (en) Method for preparing natural humanized antibody
DK0724432T3 (en) Methods and compositions for microencapsulating antigens for use as vaccines
DK0587780T4 (en) Infectious agent that causes Mystery Swine Disease, vaccine preparations and diagnostic kits
GB2300982B (en) Low cost, high reliability soft start arrangement
DE69739046D1 (en) Immunogenic composition comprising tumor-associated antigen and human cytokin
DK1047784T3 (en) Neissera meningitidis antigens
EG25924A (en) A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
DE69535520D1 (en) Modified, improved BRSV live vaccine
DE69637383D1 (en) Cytotoxin conjugate comprising dipeptide
DK0941333T3 (en) Immunogenically Detoxified Mutant E. Coli LT-A Toxin
DK1645631T3 (en) Neisseria antigens and preparations
NZ521540A (en) Multivalent antibodies and uses therefor
AU6222196A (en) Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein
DK0869181T3 (en) Immunogenic Detoxified Mutants of Cholera Toxin and of LT Tolsin, Its Preparation and Its Use in the Preparation of Vaccines
DE69638016D1 (en) Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents
ZA9607502B (en) Medicament delivery device.
EP1014787A4 (en) Adjuvant for transcutaneous immunization
WO2000062800A3 (en) Adjuvant composition comprising saponin and an immunostimulatory oligonucleotide
EP1041728A3 (en) Spread-spectrum system and method
CA2267456A1 (en) Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
HK1043731A1 (en) Vaccine against antigens from bacteriae
ES2110386T3 (en) Interferon conjugates.
PT2261358E (en) Novel streptococcus antigen
HK1024268A1 (en) Method for activating human antigen presenting cells, activated human antigen presenting cells, and use of the same.
CA2340174A1 (en) Compositions of cpg and saponin adjuvants and methods thereof