JP2011004753A5 - - Google Patents
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- Publication number
- JP2011004753A5 JP2011004753A5 JP2010174020A JP2010174020A JP2011004753A5 JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5 JP 2010174020 A JP2010174020 A JP 2010174020A JP 2010174020 A JP2010174020 A JP 2010174020A JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- antigenic
- antigen
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000890 antigenic effect Effects 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 15
- 102000039446 nucleic acids Human genes 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 210000004408 hybridoma Anatomy 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000000977 initiatory effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 210000004989 spleen cell Anatomy 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450087 | 2003-04-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Division JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Division JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011004753A JP2011004753A (ja) | 2011-01-13 |
| JP2011004753A5 true JP2011004753A5 (enExample) | 2011-03-10 |
Family
ID=33186037
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
| JP2010174020A Pending JP2011004753A (ja) | 2003-04-15 | 2010-08-02 | 肺炎連鎖球菌抗原 |
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7635487B2 (enExample) |
| EP (11) | EP2336357A1 (enExample) |
| JP (3) | JP2007525157A (enExample) |
| CN (2) | CN1774447B (enExample) |
| AU (1) | AU2004230244B2 (enExample) |
| CA (1) | CA2522238A1 (enExample) |
| WO (1) | WO2004092209A2 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| AU2002351623A1 (en) | 2001-12-20 | 2003-07-09 | Shire Biochem Inc. | Streptococcus antigens |
| JP2007512006A (ja) * | 2003-11-10 | 2007-05-17 | ザ ユーエービー リサーチ ファウンデーション | 細菌輸送およびｃｎｓ侵襲を低減させるための組成物およびこの組成物を使用する方法 |
| AU2007285775B2 (en) * | 2006-08-17 | 2011-03-03 | Sanofi Pasteur Ltd. | Immunogenic PcpA polypeptides and uses thereof |
| WO2008039838A2 (en) | 2006-09-27 | 2008-04-03 | St. Jude Children's Research Hospital | Synthetic streptococcus pneumoniae vaccine |
| EP1923069A1 (en) * | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| AU2007353789B2 (en) * | 2007-05-23 | 2014-05-22 | The Uab Research Foundation | Detoxified pneumococcal neuraminidase and uses thereof |
| AU2008256340A1 (en) * | 2007-05-25 | 2008-12-04 | Novartis Ag | Streptococcus pneumoniae pilus antigens |
| AU2008280799B2 (en) * | 2007-07-23 | 2013-07-11 | Sanofi Pasteur Limited | Immunogenic polypeptides and monoclonal antibodies |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| AU2009208299B2 (en) * | 2008-02-01 | 2015-01-22 | Sanofi Pasteur Limited | Assay for diagnosing streptococcus pneumoniae |
| PL2268618T3 (pl) | 2008-03-03 | 2015-11-30 | Novartis Ag | Związki i kompozycje jako modulatory aktywności receptorów TLR |
| CN101977927A (zh) * | 2008-03-17 | 2011-02-16 | 英特塞尔股份公司 | 针对肺炎链球菌保护的肽以及与其有关的组合物、方法和用途 |
| EP2108656A1 (en) * | 2008-03-19 | 2009-10-14 | Beninati, Concetta | Antigenic protein fragments of streptococcus pneumoniae |
| US11839430B2 (en) | 2008-03-27 | 2023-12-12 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| US8348429B2 (en) | 2008-03-27 | 2013-01-08 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| US20110171224A1 (en) * | 2008-05-22 | 2011-07-14 | Orihuela Carlos J | PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION |
| EP3884844A1 (en) | 2008-07-18 | 2021-09-29 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| ES2352704B1 (es) * | 2008-08-08 | 2012-06-14 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) | Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones. |
| US20110196142A1 (en) * | 2008-09-04 | 2011-08-11 | Biotechnology Research Institute The Chinese Academy of Agricultural Sciences | DNA molecule for expressing Hairpin RNA, the constructing method and the use thereof |
| EP2328611A4 (en) * | 2008-09-11 | 2011-10-12 | Univ Ben Gurion | COMPOSITIONS AND METHODS FOR THE TREATMENT OF S. PNEUMONIAE INFECTION |
| EP2218457B1 (en) | 2009-02-16 | 2011-09-07 | Karlsruher Institut für Technologie | CD44v6 peptides as inhibitors of bacterial infections |
| BRPI1009829A2 (pt) | 2009-03-24 | 2016-11-16 | Novartis Ag | combinações de proteína de ligação de fator h meningocócico e conjugados de sacarídeos pneumocócicos |
| CN102762226A (zh) | 2009-06-10 | 2012-10-31 | 诺华有限公司 | 含苯并萘啶的疫苗 |
| MX2012000158A (es) * | 2009-06-29 | 2012-06-08 | Genocea Biosciences Inc | Vacunas y composiciones contra streptococcus pneumoniae. |
| JO3257B1 (ar) | 2009-09-02 | 2018-09-16 | Novartis Ag | مركبات وتركيبات كمعدلات لفاعلية tlr |
| ES2443952T3 (es) | 2009-09-02 | 2014-02-21 | Novartis Ag | Composiciones inmunógenas que incluyen moduladores de la actividad de TLR |
| US20120237536A1 (en) | 2009-09-10 | 2012-09-20 | Novartis | Combination vaccines against respiratory tract diseases |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| US9408907B2 (en) | 2009-12-15 | 2016-08-09 | Glaxosmithkline Biologicals Sa | Homogenous suspension of immunopotentiating compounds and uses thereof |
| WO2011112906A2 (en) | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| JP5848748B2 (ja) | 2010-03-23 | 2016-01-27 | アイアールエム・リミテッド・ライアビリティ・カンパニーＩｒｍ，Ｌｌｃ | 感染症、炎症、呼吸器疾患などの処置に使用するｔｌｒ２アゴニストとしての化合物（システインベースのリポペプチド）および組成物 |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| CA2819758A1 (en) | 2010-12-03 | 2012-06-07 | Sanofi Pasteur Limited | Composition for immunization against streptococcus pneumoniae |
| CN105833260A (zh) * | 2011-01-20 | 2016-08-10 | 健诺西生物科学公司 | 针对肺炎链球菌（Streptococcus Pneumoniae）的疫苗和组合物 |
| ES2864764T3 (es) | 2011-05-11 | 2021-10-14 | Childrens Medical Center | Composición inmunogénica que presenta múltiples antígenos, y métodos y usos de la misma |
| JP6170932B2 (ja) | 2011-11-07 | 2017-07-26 | ノバルティス アーゲー | ｓｐｒ００９６抗原およびｓｐｒ２０２１抗原を含むキャリア分子 |
| US20150273042A1 (en) * | 2012-02-24 | 2015-10-01 | Novartis Ag | Pilus proteins and compositions |
| JP2015510872A (ja) | 2012-03-07 | 2015-04-13 | ノバルティス アーゲー | Ｓｔｒｅｐｔｏｃｏｃｃｕｓｐｎｅｕｍｏｎｉａｅ抗原の増強された製剤 |
| AU2013265336A1 (en) | 2012-05-22 | 2014-12-04 | Novartis Ag | Meningococcus serogroup X conjugate |
| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
| WO2014018904A1 (en) * | 2012-07-26 | 2014-01-30 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| TR201807340T4 (tr) | 2013-02-01 | 2018-06-21 | Glaxosmithkline Biologicals Sa | Çan benzeri reseptör agonistleri içeren immünolojik kompozisyonların intradermal yoldan verilmesi. |
| WO2014124228A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US10772497B2 (en) | 2014-09-12 | 2020-09-15 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| WO2017048873A1 (en) | 2015-09-17 | 2017-03-23 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| US9226856B2 (en) | 2013-03-14 | 2016-01-05 | Envision Diagnostics, Inc. | Inflatable medical interfaces and other medical devices, systems, and methods |
| US20180223326A1 (en) * | 2015-06-18 | 2018-08-09 | The Research Foundation For Microbial Diseases Of Osaka University | Method For Measuring Complement-Dependent Bactericidal Function With Respect To Pneumococci |
| EP3448234A4 (en) | 2016-04-30 | 2019-05-01 | Envision Diagnostics, Inc. | MEDICAL DEVICES, SYSTEMS AND METHODS FOR PERFORMING EYE EXAMINATIONS AND EYES TRACKING |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US20200038499A1 (en) * | 2017-03-22 | 2020-02-06 | Modernatx, Inc. | Rna bacterial vaccines |
| CN110730670A (zh) | 2017-03-28 | 2020-01-24 | 儿童医疗中心有限公司 | 基于多抗原提呈系统(maps)的金黄色葡萄球菌疫苗、免疫原性组合物以及它们的用途 |
| JP2020525540A (ja) | 2017-06-23 | 2020-08-27 | ノソコミアル ヴァクスィーン コーポレイション | 免疫原性組成物 |
| IL276608B2 (en) | 2018-02-12 | 2024-04-01 | Inimmune Corp | Toll-like receptor ligands |
| GB201807380D0 (en) * | 2018-05-04 | 2018-06-20 | Karlsson Roger | Biomarkers for detecting microbial infection |
| JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
| JP7535791B2 (ja) | 2018-09-12 | 2024-08-19 | ザ チルドレンズ メディカル センター コーポレーション | 肺炎球菌融合タンパク質ワクチン |
| RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
| CN111748535B (zh) * | 2019-03-28 | 2022-07-05 | 安徽华恒生物科技股份有限公司 | 一种丙氨酸脱氢酶突变体及其在发酵生产l-丙氨酸中的应用 |
| JP2023547676A (ja) | 2020-11-04 | 2023-11-13 | エリゴ・バイオサイエンス | ＤＮＡペイロードをアクネ菌集団へとｉｎ ｓｉｔｕ送達するためのファージ由来粒子 |
| GB202100097D0 (en) * | 2021-01-05 | 2021-02-17 | Univ Liverpool | Novel composition |
| WO2023039223A1 (en) | 2021-09-09 | 2023-03-16 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
| CN118302523B (zh) * | 2022-06-07 | 2025-05-06 | 北京大学第一医院 | 包含IgA蛋白酶截短体的融合蛋白及其用途 |
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| US40000A (en) | 1863-09-15 | Improvement in sewing-machines | ||
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| KR970002255B1 (ko) | 1990-06-11 | 1997-02-26 | 넥스스타 파아마슈티컬드, 인크. | 핵산 리간드 |
| DK0464533T3 (da) | 1990-06-28 | 1999-04-26 | Gen Hospital Corp | Fusionsproteiner med immunglobulindele, deres fremstilling og anvendelse |
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| EP0772619B2 (en) | 1994-07-15 | 2010-12-08 | The University of Iowa Research Foundation | Immunomodulatory oligonucleotides |
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| EP1648500B1 (en) | 2003-07-31 | 2014-07-09 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic compositions for streptococcus pyogenes |
-
2004
- 2004-04-15 EP EP10178910A patent/EP2336357A1/en not_active Withdrawn
- 2004-04-15 AU AU2004230244A patent/AU2004230244B2/en not_active Ceased
- 2004-04-15 CN CN200480010200XA patent/CN1774447B/zh not_active Expired - Fee Related
- 2004-04-15 CA CA002522238A patent/CA2522238A1/en not_active Abandoned
- 2004-04-15 CN CN2011100423445A patent/CN102174534A/zh active Pending
- 2004-04-15 EP EP10178949A patent/EP2311990A1/en not_active Withdrawn
- 2004-04-15 EP EP10178932A patent/EP2314719A1/en not_active Withdrawn
- 2004-04-15 EP EP10178885A patent/EP2311988A1/en not_active Withdrawn
- 2004-04-15 EP EP04727537A patent/EP1615950A2/en not_active Withdrawn
- 2004-04-15 EP EP10178937A patent/EP2333114A1/en not_active Withdrawn
- 2004-04-15 US US10/552,156 patent/US7635487B2/en not_active Expired - Fee Related
- 2004-04-15 EP EP10178893A patent/EP2314718A1/en not_active Withdrawn
- 2004-04-15 WO PCT/EP2004/003984 patent/WO2004092209A2/en not_active Ceased
- 2004-04-15 EP EP10178954A patent/EP2311991A1/en not_active Withdrawn
- 2004-04-15 EP EP10178944A patent/EP2311989A1/en not_active Withdrawn
- 2004-04-15 EP EP10178902A patent/EP2298934A1/en not_active Withdrawn
- 2004-04-15 JP JP2006505135A patent/JP2007525157A/ja active Pending
- 2004-04-15 EP EP10178877A patent/EP2311987A1/en not_active Withdrawn
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2009
- 2009-12-14 US US12/637,589 patent/US8372411B2/en not_active Expired - Fee Related
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2010
- 2010-08-02 JP JP2010174020A patent/JP2011004753A/ja active Pending
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2012
- 2012-04-25 JP JP2012099977A patent/JP2012184236A/ja active Pending
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2013
- 2013-01-31 US US13/755,399 patent/US20130136761A1/en not_active Abandoned