JP2011004753A5 - - Google Patents
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- Publication number
- JP2011004753A5 JP2011004753A5 JP2010174020A JP2010174020A JP2011004753A5 JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5 JP 2010174020 A JP2010174020 A JP 2010174020A JP 2010174020 A JP2010174020 A JP 2010174020A JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- antigenic
- antigen
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000890 antigenic effect Effects 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 15
- 102000039446 nucleic acids Human genes 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 210000004408 hybridoma Anatomy 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000000977 initiatory effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 210000004989 spleen cell Anatomy 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450087 | 2003-04-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Division JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Division JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011004753A JP2011004753A (ja) | 2011-01-13 |
| JP2011004753A5 true JP2011004753A5 (enExample) | 2011-03-10 |
Family
ID=33186037
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
| JP2010174020A Pending JP2011004753A (ja) | 2003-04-15 | 2010-08-02 | 肺炎連鎖球菌抗原 |
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7635487B2 (enExample) |
| EP (11) | EP2336357A1 (enExample) |
| JP (3) | JP2007525157A (enExample) |
| CN (2) | CN1774447B (enExample) |
| AU (1) | AU2004230244B2 (enExample) |
| CA (1) | CA2522238A1 (enExample) |
| WO (1) | WO2004092209A2 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| US7262024B2 (en) | 2001-12-20 | 2007-08-28 | Id Biomedical Corporation | Streptococcus antigens |
| AU2004289295B2 (en) * | 2003-11-10 | 2010-08-12 | The Uab Research Foundation | Compositions for reducing bacterial carriage and CNS invasion and methods of using same |
| JP5081243B2 (ja) * | 2006-08-17 | 2012-11-28 | ザ ユーエービー リサーチ ファウンデーション | 肺炎球菌抗原を被検体における肺炎球菌性肺炎の指標とする方法 |
| US8722055B2 (en) * | 2006-09-27 | 2014-05-13 | St. Jude Children's Research Hospital | Synthetic Streptococcus pneumoniae vaccine |
| EP1923069A1 (en) * | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| MX2009012676A (es) | 2007-05-23 | 2010-02-12 | Uab Research Foundation | Neuraminidasa neumococica no toxica y sus usos. |
| BRPI0811908A2 (pt) * | 2007-05-25 | 2014-11-18 | Novartis Ag | Antígenos de pilus de streptococcus pneumoniae |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| CN101802198B (zh) * | 2007-07-23 | 2016-02-17 | 圣诺菲·帕斯图尔有限公司 | 免疫原性多肽和单克隆抗体 |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| CN105044337A (zh) * | 2008-02-01 | 2015-11-11 | 圣诺菲·帕斯图尔有限公司 | 用于诊断肺炎链球菌的试验 |
| PT2268618E (pt) | 2008-03-03 | 2015-10-12 | Novartis Ag | Compostos e composições moduladores da actividade tlr |
| AU2009226949A1 (en) | 2008-03-17 | 2009-09-24 | Intercell Ag | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| EP2108656A1 (en) * | 2008-03-19 | 2009-10-14 | Beninati, Concetta | Antigenic protein fragments of streptococcus pneumoniae |
| US11839430B2 (en) | 2008-03-27 | 2023-12-12 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| US8348429B2 (en) | 2008-03-27 | 2013-01-08 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| US20110171224A1 (en) * | 2008-05-22 | 2011-07-14 | Orihuela Carlos J | PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION |
| WO2010009450A1 (en) | 2008-07-18 | 2010-01-21 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| ES2352704B1 (es) * | 2008-08-08 | 2012-06-14 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) | Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones. |
| EP2327782B1 (en) * | 2008-09-04 | 2015-02-25 | Biotechnology Research Institute Chinese Academy of Agricultural Sciences | Dna molecule for expressing haripin rna, the constructing method and the use thereof |
| WO2010029546A2 (en) * | 2008-09-11 | 2010-03-18 | Ben Gurion University Of The Negev Research And Development Authority | Compositions and methods for treating s.pneumoniae infection |
| EP2218457B1 (en) * | 2009-02-16 | 2011-09-07 | Karlsruher Institut für Technologie | CD44v6 peptides as inhibitors of bacterial infections |
| NZ595291A (en) | 2009-03-24 | 2013-08-30 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| AU2010258677B2 (en) | 2009-06-10 | 2016-10-06 | Glaxosmithkline Biologicals S.A. | Benzonaphthyridine-containing vaccines |
| SG10201403702SA (en) * | 2009-06-29 | 2014-09-26 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
| JP5988492B2 (ja) | 2009-09-02 | 2016-09-07 | ノバルティス アーゲー | Ｔｌｒ活性モジュレーターを含む免疫原性組成物 |
| TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為ｔｌｒ活性調節劑之化合物及組合物 |
| WO2011030218A1 (en) | 2009-09-10 | 2011-03-17 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| WO2011084549A1 (en) | 2009-12-15 | 2011-07-14 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| JP2013525271A (ja) * | 2010-03-12 | 2013-06-20 | チルドレンズ メディカル センター コーポレーション | 免疫原およびそのスクリーニング方法 |
| EA031379B1 (ru) | 2010-03-23 | 2018-12-28 | Новартис Аг | Соединения (липопептиды на основе цистеина) и композиции в качестве агонистов tlr2, применяемые для лечения инфекционных, воспалительных, респираторных и других заболеваний |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| JP6046632B2 (ja) | 2010-12-03 | 2016-12-21 | サノフィ パストゥール リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ | 肺炎球菌に対する免疫用組成物 |
| MY163871A (en) * | 2011-01-20 | 2017-10-31 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
| ES2864764T3 (es) | 2011-05-11 | 2021-10-14 | Childrens Medical Center | Composición inmunogénica que presenta múltiples antígenos, y métodos y usos de la misma |
| AU2012335208B2 (en) | 2011-11-07 | 2017-08-31 | Glaxosmithkline Biologicals S.A. | Carrier molecule comprising a spr0096 and a spr2021 antigen |
| AU2013224026A1 (en) * | 2012-02-24 | 2014-08-21 | Novartis Ag | Pilus proteins and compositions |
| CN104519910B (zh) | 2012-03-07 | 2017-05-03 | 诺华股份有限公司 | 肺炎链球菌抗原的含佐剂制剂 |
| ES2820898T3 (es) | 2012-05-22 | 2021-04-22 | Glaxosmithkline Biologicals Sa | Conjugado del serogrupo X de meningococos |
| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
| WO2014018904A1 (en) * | 2012-07-26 | 2014-01-30 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| ES2670863T3 (es) | 2013-02-01 | 2018-06-01 | Glaxosmithkline Biologicals Sa | Administración intradérmica de composiciones inmunológicas que comprenden agonistas del receptor de tipo Toll |
| EP4272750A3 (en) | 2013-02-07 | 2024-01-24 | Children's Medical Center, Corp. | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US9226856B2 (en) | 2013-03-14 | 2016-01-05 | Envision Diagnostics, Inc. | Inflatable medical interfaces and other medical devices, systems, and methods |
| US10772497B2 (en) | 2014-09-12 | 2020-09-15 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| CN108138216A (zh) * | 2015-06-18 | 2018-06-08 | 般财团法人阪大微生物病研究会 | 肺炎球菌补体依赖性杀菌能力测量方法 |
| EP3834705B1 (en) | 2015-09-17 | 2023-12-20 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| WO2017190087A1 (en) | 2016-04-30 | 2017-11-02 | Envision Diagnostics, Inc. | Medical devices, systems, and methods for performing eye exams and eye tracking |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US20200038499A1 (en) * | 2017-03-22 | 2020-02-06 | Modernatx, Inc. | Rna bacterial vaccines |
| US11305001B2 (en) | 2017-03-28 | 2022-04-19 | The Children's Medical Center Corporation | Multiple antigen presenting system (MAPS)-based Staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
| CN111065417B (zh) | 2017-06-23 | 2024-04-19 | 美商艾芬尼维克斯公司 | 免疫原性组合物 |
| US11458151B2 (en) | 2018-02-12 | 2022-10-04 | Inimmune Corporation | Toll-like receptor ligands |
| GB201807380D0 (en) | 2018-05-04 | 2018-06-20 | Karlsson Roger | Biomarkers for detecting microbial infection |
| SG11202101973YA (en) | 2018-09-12 | 2021-03-30 | Childrens Medical Ct Corp | Pneumococcal fusion protein vaccines |
| PE20211112A1 (es) | 2018-09-12 | 2021-06-22 | Affinivax Inc | Vacunas neumococicas multivalentes |
| RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
| CN111748535B (zh) * | 2019-03-28 | 2022-07-05 | 安徽华恒生物科技股份有限公司 | 一种丙氨酸脱氢酶突变体及其在发酵生产l-丙氨酸中的应用 |
| JP2023547677A (ja) | 2020-11-04 | 2023-11-13 | エリゴ・バイオサイエンス | キューティバクテリウム・アクネス組換えファージ、その産生方法及び使用 |
| GB202100097D0 (en) * | 2021-01-05 | 2021-02-17 | Univ Liverpool | Novel composition |
| WO2023039223A1 (en) | 2021-09-09 | 2023-03-16 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
| JP2025523396A (ja) * | 2022-06-07 | 2025-07-23 | ペキン ユニバーシティ ファースト ホスピタル | ＩｇＡプロテアーゼトランケートを含む融合タンパク質及びその用途 |
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| US40000A (en) | 1863-09-15 | Improvement in sewing-machines | ||
| US4609231A (en) | 1984-12-24 | 1986-09-02 | Perfectdata Corporation | Floppy diskette storage container |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
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| WO2000006738A2 (en) * | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | NUCLEIC ACIDS AND PROTEINS FROM $i(STREPTOCOCCUS PNEUMONIAE) |
| US6951652B2 (en) * | 1998-07-29 | 2005-10-04 | Biosynth S.R.L. | Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases |
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-
2004
- 2004-04-15 CA CA002522238A patent/CA2522238A1/en not_active Abandoned
- 2004-04-15 EP EP10178910A patent/EP2336357A1/en not_active Withdrawn
- 2004-04-15 JP JP2006505135A patent/JP2007525157A/ja active Pending
- 2004-04-15 EP EP10178893A patent/EP2314718A1/en not_active Withdrawn
- 2004-04-15 EP EP10178932A patent/EP2314719A1/en not_active Withdrawn
- 2004-04-15 EP EP10178944A patent/EP2311989A1/en not_active Withdrawn
- 2004-04-15 EP EP10178949A patent/EP2311990A1/en not_active Withdrawn
- 2004-04-15 CN CN200480010200XA patent/CN1774447B/zh not_active Expired - Fee Related
- 2004-04-15 EP EP04727537A patent/EP1615950A2/en not_active Withdrawn
- 2004-04-15 EP EP10178877A patent/EP2311987A1/en not_active Withdrawn
- 2004-04-15 EP EP10178937A patent/EP2333114A1/en not_active Withdrawn
- 2004-04-15 EP EP10178885A patent/EP2311988A1/en not_active Withdrawn
- 2004-04-15 EP EP10178902A patent/EP2298934A1/en not_active Withdrawn
- 2004-04-15 EP EP10178954A patent/EP2311991A1/en not_active Withdrawn
- 2004-04-15 WO PCT/EP2004/003984 patent/WO2004092209A2/en not_active Ceased
- 2004-04-15 US US10/552,156 patent/US7635487B2/en not_active Expired - Fee Related
- 2004-04-15 CN CN2011100423445A patent/CN102174534A/zh active Pending
- 2004-04-15 AU AU2004230244A patent/AU2004230244B2/en not_active Ceased
-
2009
- 2009-12-14 US US12/637,589 patent/US8372411B2/en not_active Expired - Fee Related
-
2010
- 2010-08-02 JP JP2010174020A patent/JP2011004753A/ja active Pending
-
2012
- 2012-04-25 JP JP2012099977A patent/JP2012184236A/ja active Pending
-
2013
- 2013-01-31 US US13/755,399 patent/US20130136761A1/en not_active Abandoned