JP2011004753A5 - - Google Patents
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- Publication number
- JP2011004753A5 JP2011004753A5 JP2010174020A JP2010174020A JP2011004753A5 JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5 JP 2010174020 A JP2010174020 A JP 2010174020A JP 2010174020 A JP2010174020 A JP 2010174020A JP 2011004753 A5 JP2011004753 A5 JP 2011004753A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- antigenic
- antigen
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000890 antigenic effect Effects 0.000 claims 18
- 150000007523 nucleic acids Chemical class 0.000 claims 16
- 108020004707 nucleic acids Proteins 0.000 claims 15
- 102000039446 nucleic acids Human genes 0.000 claims 15
- 239000012634 fragment Substances 0.000 claims 12
- 239000000427 antigen Substances 0.000 claims 10
- 102000036639 antigens Human genes 0.000 claims 10
- 108091007433 antigens Proteins 0.000 claims 10
- 229920001184 polypeptide Polymers 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 210000004408 hybridoma Anatomy 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000000977 initiatory effect Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 210000000952 spleen Anatomy 0.000 claims 2
- 210000004989 spleen cell Anatomy 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000010367 cloning Methods 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000003248 secreting effect Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450087 | 2003-04-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Division JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Division JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011004753A JP2011004753A (ja) | 2011-01-13 |
| JP2011004753A5 true JP2011004753A5 (enExample) | 2011-03-10 |
Family
ID=33186037
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
| JP2010174020A Pending JP2011004753A (ja) | 2003-04-15 | 2010-08-02 | 肺炎連鎖球菌抗原 |
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505135A Pending JP2007525157A (ja) | 2003-04-15 | 2004-04-15 | 肺炎連鎖球菌抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012099977A Pending JP2012184236A (ja) | 2003-04-15 | 2012-04-25 | 肺炎連鎖球菌抗原 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7635487B2 (enExample) |
| EP (11) | EP2311989A1 (enExample) |
| JP (3) | JP2007525157A (enExample) |
| CN (2) | CN102174534A (enExample) |
| AU (1) | AU2004230244B2 (enExample) |
| CA (1) | CA2522238A1 (enExample) |
| WO (1) | WO2004092209A2 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7128918B1 (en) * | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| EP1456231A2 (en) | 2001-12-20 | 2004-09-15 | Shire Biochem Inc. | Streptococcus antigens |
| AU2004289295B2 (en) | 2003-11-10 | 2010-08-12 | The Uab Research Foundation | Compositions for reducing bacterial carriage and CNS invasion and methods of using same |
| MX2009001778A (es) * | 2006-08-17 | 2009-05-22 | Uab Research Foundation | Peptidos pcpa inmunogenicos y usos de los mismos. |
| WO2008039838A2 (en) * | 2006-09-27 | 2008-04-03 | St. Jude Children's Research Hospital | Synthetic streptococcus pneumoniae vaccine |
| EP1923069A1 (en) | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| EP2164957B1 (en) | 2007-05-23 | 2017-07-12 | The UAB Research Foundation | Detoxified pneumococcal neuraminidase and uses thereof |
| BRPI0811908A2 (pt) * | 2007-05-25 | 2014-11-18 | Novartis Ag | Antígenos de pilus de streptococcus pneumoniae |
| KR101595234B1 (ko) * | 2007-07-23 | 2016-02-26 | 사노피 파스퇴르 리미티드 | 면역원성 폴리펩타이드 및 단일클론 항체 |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| JP5697991B2 (ja) * | 2008-02-01 | 2015-04-08 | サノフィ パストゥール リミテッドSanofi Pasteur Limited | 診断的アッセイ |
| SI2268618T1 (sl) | 2008-03-03 | 2015-09-30 | Novartis Ag | Spojine in sestavki kot modulatorji aktivnosti TLR |
| WO2009115508A2 (en) * | 2008-03-17 | 2009-09-24 | Intercell Ag | Peptides protective against s. pneumoniae and compositions, methods and uses relating thereto |
| EP2108656A1 (en) * | 2008-03-19 | 2009-10-14 | Beninati, Concetta | Antigenic protein fragments of streptococcus pneumoniae |
| US8348429B2 (en) | 2008-03-27 | 2013-01-08 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| US11839430B2 (en) | 2008-03-27 | 2023-12-12 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| WO2009143483A2 (en) * | 2008-05-22 | 2009-11-26 | The Board Of Regents Of The University Of Texas System | PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION |
| WO2010009450A1 (en) | 2008-07-18 | 2010-01-21 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| ES2352704B1 (es) * | 2008-08-08 | 2012-06-14 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) | Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones. |
| EP2327782B1 (en) * | 2008-09-04 | 2015-02-25 | Biotechnology Research Institute Chinese Academy of Agricultural Sciences | Dna molecule for expressing haripin rna, the constructing method and the use thereof |
| EP2328611A4 (en) * | 2008-09-11 | 2011-10-12 | Univ Ben Gurion | COMPOSITIONS AND METHODS FOR THE TREATMENT OF S. PNEUMONIAE INFECTION |
| ATE523204T1 (de) | 2009-02-16 | 2011-09-15 | Karlsruher Inst Technologie | Cd44v6-peptide als bakterielle infektionsinhibitoren |
| JP5668049B2 (ja) | 2009-03-24 | 2015-02-12 | ノバルティス アーゲー | 髄膜炎菌h因子結合タンパク質および肺炎球菌糖結合体の組み合わせ |
| EP2440245B1 (en) | 2009-06-10 | 2017-12-06 | GlaxoSmithKline Biologicals SA | Benzonaphthyridine-containing vaccines |
| JP5931724B2 (ja) * | 2009-06-29 | 2016-06-08 | ジェノセア バイオサイエンシーズ, インコーポレイテッド | StreptococcusPneumoniaeに対するワクチンおよび組成物 |
| TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為tlr活性調節劑之化合物及組合物 |
| BR112012004806B8 (pt) | 2009-09-02 | 2022-10-04 | Novartis Ag | composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso |
| CA2773637A1 (en) | 2009-09-10 | 2011-03-17 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| WO2011057148A1 (en) | 2009-11-05 | 2011-05-12 | Irm Llc | Compounds and compositions as tlr-7 activity modulators |
| WO2011084549A1 (en) | 2009-12-15 | 2011-07-14 | Novartis Ag | Homogeneous suspension of immunopotentiating compounds and uses thereof |
| WO2011112906A2 (en) * | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| CA2792938C (en) | 2010-03-23 | 2018-07-31 | Irm Llc | Compounds (cystein based lipopeptides) and compositions as tlr2 agonists used for treating infections, inflammations, respiratory diseases etc. |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| RU2589256C2 (ru) | 2010-12-03 | 2016-07-10 | Санофи Пастер Лимитид | Композиции и способы для иммунизации против streptococcus pneumoniae |
| WO2012100233A1 (en) * | 2011-01-20 | 2012-07-26 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
| KR102084509B1 (ko) | 2011-05-11 | 2020-03-05 | 칠드런'즈 메디컬 센터 코포레이션 | 변형 비오틴-결합 단백질, 그 융합 단백질 및 응용 |
| JP6170932B2 (ja) | 2011-11-07 | 2017-07-26 | ノバルティス アーゲー | spr0096抗原およびspr2021抗原を含むキャリア分子 |
| AU2013224026A1 (en) * | 2012-02-24 | 2014-08-21 | Novartis Ag | Pilus proteins and compositions |
| US20150132339A1 (en) | 2012-03-07 | 2015-05-14 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
| ES2820898T3 (es) | 2012-05-22 | 2021-04-22 | Glaxosmithkline Biologicals Sa | Conjugado del serogrupo X de meningococos |
| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
| WO2014018904A1 (en) * | 2012-07-26 | 2014-01-30 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
| EP2950819B1 (en) | 2013-02-01 | 2018-03-28 | GlaxoSmithKline Biologicals SA | Intradermal delivery of immunological compositions comprising toll-like receptor agonists |
| US11576958B2 (en) | 2013-02-07 | 2023-02-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US10772497B2 (en) | 2014-09-12 | 2020-09-15 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| US9226856B2 (en) | 2013-03-14 | 2016-01-05 | Envision Diagnostics, Inc. | Inflatable medical interfaces and other medical devices, systems, and methods |
| US20180223326A1 (en) * | 2015-06-18 | 2018-08-09 | The Research Foundation For Microbial Diseases Of Osaka University | Method For Measuring Complement-Dependent Bactericidal Function With Respect To Pneumococci |
| EP3834705B1 (en) | 2015-09-17 | 2023-12-20 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| WO2017190087A1 (en) | 2016-04-30 | 2017-11-02 | Envision Diagnostics, Inc. | Medical devices, systems, and methods for performing eye exams and eye tracking |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US20200038499A1 (en) * | 2017-03-22 | 2020-02-06 | Modernatx, Inc. | Rna bacterial vaccines |
| WO2018183475A1 (en) | 2017-03-28 | 2018-10-04 | Children's Medical Center Corporation | A multiple antigen presenting system (maps)-based staphylococcus aureus vaccine, immunogenic composition, and uses thereof |
| MX2019015524A (es) | 2017-06-23 | 2020-09-10 | Univ Maryland | Composiciones inmunogenicas. |
| CA3090271A1 (en) | 2018-02-12 | 2019-08-15 | Inimmune Corporation | Toll-like receptor ligands |
| GB201807380D0 (en) * | 2018-05-04 | 2018-06-20 | Karlsson Roger | Biomarkers for detecting microbial infection |
| PE20211112A1 (es) | 2018-09-12 | 2021-06-22 | Affinivax Inc | Vacunas neumococicas multivalentes |
| MX2021002909A (es) | 2018-09-12 | 2021-09-08 | Childrens Medical Ct Corp | Vacunas de proteinas de fusion neumococicas. |
| RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
| CN111748535B (zh) * | 2019-03-28 | 2022-07-05 | 安徽华恒生物科技股份有限公司 | 一种丙氨酸脱氢酶突变体及其在发酵生产l-丙氨酸中的应用 |
| WO2022096590A1 (en) | 2020-11-04 | 2022-05-12 | Eligo Bioscience | Phage-derived particles for in situ delivery of dna payload into c. acnes population |
| GB202100097D0 (en) * | 2021-01-05 | 2021-02-17 | Univ Liverpool | Novel composition |
| EP4398933A1 (en) | 2021-09-09 | 2024-07-17 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
| JP2025523396A (ja) * | 2022-06-07 | 2025-07-23 | ペキン ユニバーシティ ファースト ホスピタル | IgAプロテアーゼトランケートを含む融合タンパク質及びその用途 |
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| US40000A (en) | 1863-09-15 | Improvement in sewing-machines | ||
| US4609231A (en) | 1984-12-24 | 1986-09-02 | Perfectdata Corporation | Floppy diskette storage container |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0533838B1 (en) | 1990-06-11 | 1997-12-03 | NeXstar Pharmaceuticals, Inc. | Nucleic acid ligands |
| DK0464533T3 (da) | 1990-06-28 | 1999-04-26 | Gen Hospital Corp | Fusionsproteiner med immunglobulindele, deres fremstilling og anvendelse |
| EP0591431B1 (en) | 1991-06-24 | 2002-12-11 | Chiron Corporation | Hepatitis c virus (hcv) polypeptides |
| ES2366201T3 (es) | 1994-07-15 | 2011-10-18 | University Of Iowa Research Foundation | Oligonucleótidos inmunmoduladores. |
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| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| DE19803453A1 (de) | 1998-01-30 | 1999-08-12 | Boehringer Ingelheim Int | Vakzine |
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| AU2027400A (en) * | 1998-11-19 | 2000-06-05 | St. Jude Children's Research Hospital | Identification and characterization of novel pneumococcal choline binding proteins, cbpg and cbpd, and diagnostic and therapeutic uses thereof |
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| JP2005519035A (ja) | 2001-12-07 | 2005-06-30 | インターツェル・アクチェンゲゼルシャフト | 免疫促進性オリゴデオキシヌクレオチド |
| GB0210128D0 (en) | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
| JP4875490B2 (ja) | 2003-07-31 | 2012-02-15 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | StreptococcusPyogenesについての免疫原組成物 |
-
2004
- 2004-04-15 CN CN2011100423445A patent/CN102174534A/zh active Pending
- 2004-04-15 AU AU2004230244A patent/AU2004230244B2/en not_active Ceased
- 2004-04-15 EP EP10178944A patent/EP2311989A1/en not_active Withdrawn
- 2004-04-15 EP EP10178937A patent/EP2333114A1/en not_active Withdrawn
- 2004-04-15 EP EP10178949A patent/EP2311990A1/en not_active Withdrawn
- 2004-04-15 US US10/552,156 patent/US7635487B2/en not_active Expired - Fee Related
- 2004-04-15 WO PCT/EP2004/003984 patent/WO2004092209A2/en not_active Ceased
- 2004-04-15 EP EP10178910A patent/EP2336357A1/en not_active Withdrawn
- 2004-04-15 CN CN200480010200XA patent/CN1774447B/zh not_active Expired - Fee Related
- 2004-04-15 JP JP2006505135A patent/JP2007525157A/ja active Pending
- 2004-04-15 EP EP10178893A patent/EP2314718A1/en not_active Withdrawn
- 2004-04-15 CA CA002522238A patent/CA2522238A1/en not_active Abandoned
- 2004-04-15 EP EP04727537A patent/EP1615950A2/en not_active Withdrawn
- 2004-04-15 EP EP10178902A patent/EP2298934A1/en not_active Withdrawn
- 2004-04-15 EP EP10178877A patent/EP2311987A1/en not_active Withdrawn
- 2004-04-15 EP EP10178932A patent/EP2314719A1/en not_active Withdrawn
- 2004-04-15 EP EP10178885A patent/EP2311988A1/en not_active Withdrawn
- 2004-04-15 EP EP10178954A patent/EP2311991A1/en not_active Withdrawn
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2009
- 2009-12-14 US US12/637,589 patent/US8372411B2/en not_active Expired - Fee Related
-
2010
- 2010-08-02 JP JP2010174020A patent/JP2011004753A/ja active Pending
-
2012
- 2012-04-25 JP JP2012099977A patent/JP2012184236A/ja active Pending
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2013
- 2013-01-31 US US13/755,399 patent/US20130136761A1/en not_active Abandoned