JP2018524019A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018524019A5 JP2018524019A5 JP2018515195A JP2018515195A JP2018524019A5 JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5 JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- molecular weight
- polypeptide
- isolated
- high molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021158128A JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562171889P | 2015-06-05 | 2015-06-05 | |
| US62/171,889 | 2015-06-05 | ||
| US201562257607P | 2015-11-19 | 2015-11-19 | |
| US62/257,607 | 2015-11-19 | ||
| PCT/US2016/035858 WO2016197018A1 (en) | 2015-06-05 | 2016-06-03 | Endostatin fragments and variants for use in treating fibrosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Division JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524019A JP2018524019A (ja) | 2018-08-30 |
| JP2018524019A5 true JP2018524019A5 (enExample) | 2019-07-04 |
| JP6952685B2 JP6952685B2 (ja) | 2021-10-20 |
Family
ID=56236074
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515195A Expired - Fee Related JP6952685B2 (ja) | 2015-06-05 | 2016-06-03 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10844392B2 (enExample) |
| EP (1) | EP3303383A1 (enExample) |
| JP (2) | JP6952685B2 (enExample) |
| KR (1) | KR20180033499A (enExample) |
| CN (2) | CN107849117B (enExample) |
| AU (2) | AU2016270428B2 (enExample) |
| BR (1) | BR112017026209A2 (enExample) |
| CA (1) | CA2988299C (enExample) |
| WO (1) | WO2016197018A1 (enExample) |
| ZA (1) | ZA201708223B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2988299C (en) * | 2015-06-05 | 2023-10-31 | Ibio, Inc. | Endostatin fragments and variants for use in treating fibrosis |
| KR20210058902A (ko) * | 2018-09-14 | 2021-05-24 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | sPD-1 변이체-FC 융합 단백질 |
| EP3996736A4 (en) * | 2019-07-10 | 2023-05-24 | Musc Foundation for Research Development | ENDOSTATIN PEPTIDES FOR THE TREATMENT OF TUMOR, FIBROSIS AND ACUTE LUNG INJURY |
| US12454551B2 (en) * | 2019-07-31 | 2025-10-28 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Peptides as inhibitors of fibrotic matrix accumulation |
| JP7493945B2 (ja) * | 2020-01-28 | 2024-06-03 | ポーラ化成工業株式会社 | 培養組織の観察方法、培養方法、評価方法及び培養器具 |
| US20230265407A1 (en) * | 2020-07-02 | 2023-08-24 | Northwestern University | Human recombinant ace2-fc mutants that decouple anti-sars-cov-2 activity from cardiovascular effects |
| CA3195315A1 (en) * | 2020-11-30 | 2022-06-02 | Fred Hutchinson Cancer Center | Compositions and methods for selective depletion of target molecules |
| WO2023039399A2 (en) * | 2021-09-07 | 2023-03-16 | Musc Foundation For Research Development | Endostatin peptides for the treatment of tumors, fibrosis and acute lung injury |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US750375A (en) | 1904-01-26 | Potato-digger | ||
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3832253A (en) | 1973-03-21 | 1974-08-27 | Baxter Laboratories Inc | Method of making an inflatable balloon catheter |
| US4667014A (en) | 1983-03-07 | 1987-05-19 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists |
| US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| CA1200416A (en) | 1983-05-13 | 1986-02-11 | Societe Des Produits Nestle S.A. | Food process |
| IT1164225B (it) | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5093258A (en) | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
| US5217879A (en) | 1989-01-12 | 1993-06-08 | Washington University | Infectious Sindbis virus vectors |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| ATE179862T1 (de) | 1989-07-06 | 1999-05-15 | Univ California | Rezeptoren für fibroblasten-wachstumsfaktoren |
| JPH04167172A (ja) | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
| US5756671A (en) | 1994-06-02 | 1998-05-26 | Mitotix, Inc. | CDC37 cell-cycle regulatory protein, and uses related thereto |
| US6080560A (en) * | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| US5541087A (en) * | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| US6165460A (en) | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
| US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| DE19535939A1 (de) | 1995-09-27 | 1997-04-03 | Agfa Gevaert Ag | Fotografisches Material |
| KR20010015868A (ko) | 1997-12-08 | 2001-02-26 | 베쓰 이스라엘 디코니스 메디칼 센터 | 피치아 효모 발현계를 사용하여 항혈관형성 단백질인엔도스타틴, 안지오스타틴 또는 레스틴을 생성시키는 방법 |
| US6218371B1 (en) | 1998-04-03 | 2001-04-17 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| KR20010052566A (ko) * | 1998-06-03 | 2001-06-25 | 윌리엄 뉴 | 엔도스타틴 단백질을 포함하는 단백질 올리고머 조성물 및이의 사용방법 |
| US6399075B1 (en) | 1998-07-02 | 2002-06-04 | President And Fellows Of Harvard College | Compositions and methods for treating Papillomavirus-infected cells |
| WO2000046350A1 (en) | 1999-02-05 | 2000-08-10 | Thomas Jefferson University | Production of biomedical peptides and proteins in plants using transcomplementation systems |
| AU3224700A (en) | 1999-02-08 | 2000-08-25 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| US7692063B2 (en) * | 2002-11-12 | 2010-04-06 | Ibio, Inc. | Production of foreign nucleic acids and polypeptides in sprout systems |
| AU2004209660A1 (en) | 2003-02-03 | 2004-08-19 | Fraunhofer Usa, Inc. | System for expression of genes in plants |
| US20060024272A1 (en) * | 2004-07-29 | 2006-02-02 | Large Scale Biology Corporation | C-terminally truncated interferon |
| JP2010531666A (ja) * | 2007-06-26 | 2010-09-30 | ユニバーシティ オブ マイアミ | 抗体−エンドスタチン融合タンパク質及びそのバリアント |
| WO2011050311A1 (en) | 2009-10-22 | 2011-04-28 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Use of endostatin peptides for the treatment of fibrosis |
| WO2013013085A2 (en) * | 2011-07-19 | 2013-01-24 | Thrasos Innovation, Inc. | Anti-fibrotic peptides and their use in methods for treating diseases and disorders characterized by fibrosis |
| CA2988299C (en) | 2015-06-05 | 2023-10-31 | Ibio, Inc. | Endostatin fragments and variants for use in treating fibrosis |
-
2016
- 2016-06-03 CA CA2988299A patent/CA2988299C/en active Active
- 2016-06-03 CN CN201680044858.5A patent/CN107849117B/zh active Active
- 2016-06-03 CN CN202210968572.3A patent/CN115925878A/zh active Pending
- 2016-06-03 JP JP2018515195A patent/JP6952685B2/ja not_active Expired - Fee Related
- 2016-06-03 BR BR112017026209A patent/BR112017026209A2/pt not_active Application Discontinuation
- 2016-06-03 EP EP16732386.4A patent/EP3303383A1/en not_active Withdrawn
- 2016-06-03 KR KR1020187000354A patent/KR20180033499A/ko not_active Ceased
- 2016-06-03 US US15/579,690 patent/US10844392B2/en not_active Expired - Fee Related
- 2016-06-03 AU AU2016270428A patent/AU2016270428B2/en not_active Ceased
- 2016-06-03 WO PCT/US2016/035858 patent/WO2016197018A1/en not_active Ceased
-
2017
- 2017-12-04 ZA ZA2017/08223A patent/ZA201708223B/en unknown
-
2020
- 2020-11-09 US US17/092,539 patent/US11912755B2/en active Active
-
2021
- 2021-02-05 AU AU2021200765A patent/AU2021200765B2/en not_active Ceased
- 2021-09-28 JP JP2021158128A patent/JP7404320B2/ja active Active