JP2018524019A5 - - Google Patents
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- JP2018524019A5 JP2018524019A5 JP2018515195A JP2018515195A JP2018524019A5 JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5 JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5
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- JP
- Japan
- Prior art keywords
- seq
- molecular weight
- polypeptide
- isolated
- high molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021158128A JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562171889P | 2015-06-05 | 2015-06-05 | |
| US62/171,889 | 2015-06-05 | ||
| US201562257607P | 2015-11-19 | 2015-11-19 | |
| US62/257,607 | 2015-11-19 | ||
| PCT/US2016/035858 WO2016197018A1 (en) | 2015-06-05 | 2016-06-03 | Endostatin fragments and variants for use in treating fibrosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Division JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524019A JP2018524019A (ja) | 2018-08-30 |
| JP2018524019A5 true JP2018524019A5 (enExample) | 2019-07-04 |
| JP6952685B2 JP6952685B2 (ja) | 2021-10-20 |
Family
ID=56236074
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515195A Expired - Fee Related JP6952685B2 (ja) | 2015-06-05 | 2016-06-03 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10844392B2 (enExample) |
| EP (1) | EP3303383A1 (enExample) |
| JP (2) | JP6952685B2 (enExample) |
| KR (1) | KR20180033499A (enExample) |
| CN (2) | CN115925878A (enExample) |
| AU (2) | AU2016270428B2 (enExample) |
| BR (1) | BR112017026209A2 (enExample) |
| CA (1) | CA2988299C (enExample) |
| WO (1) | WO2016197018A1 (enExample) |
| ZA (1) | ZA201708223B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016270428B2 (en) | 2015-06-05 | 2020-11-26 | Musc Foundation For Research Development | Endostatin fragments and variants for use in treating fibrosis |
| AU2019338416A1 (en) * | 2018-09-14 | 2021-04-29 | Akso Biopharmaceutical, Inc. | sPD-1 variant - Fc fusion proteins |
| EP3996736A4 (en) * | 2019-07-10 | 2023-05-24 | Musc Foundation for Research Development | ENDOSTATIN PEPTIDES FOR THE TREATMENT OF TUMOR, FIBROSIS AND ACUTE LUNG INJURY |
| EP3996694A1 (en) * | 2019-07-31 | 2022-05-18 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Peptides as inhibitors of fibrotic matrix accumulation |
| JP7493945B2 (ja) * | 2020-01-28 | 2024-06-03 | ポーラ化成工業株式会社 | 培養組織の観察方法、培養方法、評価方法及び培養器具 |
| WO2022006601A1 (en) * | 2020-07-02 | 2022-01-06 | Northwestern University | Human recombinant ace2-fc mutants that decouple anti-sars-cov-2 activity from cardiovascular effects |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US750375A (en) | 1904-01-26 | Potato-digger | ||
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3832253A (en) | 1973-03-21 | 1974-08-27 | Baxter Laboratories Inc | Method of making an inflatable balloon catheter |
| US4667014A (en) | 1983-03-07 | 1987-05-19 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists |
| US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| CA1200416A (en) | 1983-05-13 | 1986-02-11 | Societe Des Produits Nestle S.A. | Food process |
| IT1164225B (it) | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5093258A (en) | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
| US5217879A (en) | 1989-01-12 | 1993-06-08 | Washington University | Infectious Sindbis virus vectors |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| WO1991000916A2 (en) | 1989-07-06 | 1991-01-24 | The Regents Of The University Of California | Receptors for fibroblast growth factors |
| JPH04167172A (ja) | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
| US5756671A (en) | 1994-06-02 | 1998-05-26 | Mitotix, Inc. | CDC37 cell-cycle regulatory protein, and uses related thereto |
| US6080560A (en) * | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| US6165460A (en) | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
| US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| DE19535939A1 (de) | 1995-09-27 | 1997-04-03 | Agfa Gevaert Ag | Fotografisches Material |
| WO1999029855A1 (en) | 1997-12-08 | 1999-06-17 | Beth Israel Deaconess Medical Center | Mutants of endostatin, 'em 1' having anti-angiogenic activity and methods of use thereof |
| EP1067956B1 (en) | 1998-04-03 | 2007-03-14 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| KR20010052566A (ko) * | 1998-06-03 | 2001-06-25 | 윌리엄 뉴 | 엔도스타틴 단백질을 포함하는 단백질 올리고머 조성물 및이의 사용방법 |
| AU4859399A (en) | 1998-07-02 | 2000-01-24 | President And Fellows Of Harvard College | Compositions and methods for treating papillomavirus-infected cells |
| JP2003517280A (ja) | 1999-02-05 | 2003-05-27 | トーマス・ジェファーソン・ユニバーシティ | トランス相補性システムを用いての植物における生物医学用ペプチド及びタンパク質の生成 |
| WO2000046380A2 (en) | 1999-02-08 | 2000-08-10 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| US7491509B2 (en) | 2003-02-03 | 2009-02-17 | Fraunhofer Usa, Inc. | System for expression of genes in plants |
| US7692063B2 (en) * | 2002-11-12 | 2010-04-06 | Ibio, Inc. | Production of foreign nucleic acids and polypeptides in sprout systems |
| US20060024272A1 (en) * | 2004-07-29 | 2006-02-02 | Large Scale Biology Corporation | C-terminally truncated interferon |
| EP2173377B1 (en) * | 2007-06-26 | 2017-11-29 | University of Miami | Antibody-endostatin fusion protein and its variants |
| WO2011050311A1 (en) | 2009-10-22 | 2011-04-28 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Use of endostatin peptides for the treatment of fibrosis |
| CN106478776A (zh) * | 2011-07-19 | 2017-03-08 | 特拉索斯创新公司 | 抗纤维化肽及其在用于治疗以纤维化为特征的疾病和病症的方法中的用途 |
| AU2016270428B2 (en) | 2015-06-05 | 2020-11-26 | Musc Foundation For Research Development | Endostatin fragments and variants for use in treating fibrosis |
-
2016
- 2016-06-03 AU AU2016270428A patent/AU2016270428B2/en not_active Ceased
- 2016-06-03 KR KR1020187000354A patent/KR20180033499A/ko not_active Ceased
- 2016-06-03 WO PCT/US2016/035858 patent/WO2016197018A1/en not_active Ceased
- 2016-06-03 CN CN202210968572.3A patent/CN115925878A/zh active Pending
- 2016-06-03 BR BR112017026209A patent/BR112017026209A2/pt not_active Application Discontinuation
- 2016-06-03 US US15/579,690 patent/US10844392B2/en not_active Expired - Fee Related
- 2016-06-03 JP JP2018515195A patent/JP6952685B2/ja not_active Expired - Fee Related
- 2016-06-03 CA CA2988299A patent/CA2988299C/en active Active
- 2016-06-03 CN CN201680044858.5A patent/CN107849117B/zh active Active
- 2016-06-03 EP EP16732386.4A patent/EP3303383A1/en not_active Withdrawn
-
2017
- 2017-12-04 ZA ZA2017/08223A patent/ZA201708223B/en unknown
-
2020
- 2020-11-09 US US17/092,539 patent/US11912755B2/en active Active
-
2021
- 2021-02-05 AU AU2021200765A patent/AU2021200765B2/en not_active Ceased
- 2021-09-28 JP JP2021158128A patent/JP7404320B2/ja active Active
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