JP2018524019A5 - - Google Patents
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- JP2018524019A5 JP2018524019A5 JP2018515195A JP2018515195A JP2018524019A5 JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5 JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018515195 A JP2018515195 A JP 2018515195A JP 2018524019 A5 JP2018524019 A5 JP 2018524019A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- molecular weight
- polypeptide
- isolated
- high molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021158128A JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562171889P | 2015-06-05 | 2015-06-05 | |
| US62/171,889 | 2015-06-05 | ||
| US201562257607P | 2015-11-19 | 2015-11-19 | |
| US62/257,607 | 2015-11-19 | ||
| PCT/US2016/035858 WO2016197018A1 (en) | 2015-06-05 | 2016-06-03 | Endostatin fragments and variants for use in treating fibrosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Division JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524019A JP2018524019A (ja) | 2018-08-30 |
| JP2018524019A5 true JP2018524019A5 (enExample) | 2019-07-04 |
| JP6952685B2 JP6952685B2 (ja) | 2021-10-20 |
Family
ID=56236074
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018515195A Expired - Fee Related JP6952685B2 (ja) | 2015-06-05 | 2016-06-03 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021158128A Active JP7404320B2 (ja) | 2015-06-05 | 2021-09-28 | 線維症の治療において使用するためのエンドスタチン断片およびバリアント |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US10844392B2 (enExample) |
| EP (1) | EP3303383A1 (enExample) |
| JP (2) | JP6952685B2 (enExample) |
| KR (1) | KR20180033499A (enExample) |
| CN (2) | CN107849117B (enExample) |
| AU (2) | AU2016270428B2 (enExample) |
| BR (1) | BR112017026209A2 (enExample) |
| CA (1) | CA2988299C (enExample) |
| WO (1) | WO2016197018A1 (enExample) |
| ZA (1) | ZA201708223B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10844392B2 (en) * | 2015-06-05 | 2020-11-24 | Ibio, Inc. | Materials and methods for producing endostatin fusion polypeptides in plant cells |
| KR20210058902A (ko) * | 2018-09-14 | 2021-05-24 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | sPD-1 변이체-FC 융합 단백질 |
| WO2021007094A1 (en) * | 2019-07-10 | 2021-01-14 | Musc Foundation For Research Development | Endostatin peptides for the treatment of tumors, fibrosis and acute lung injury |
| EP3996694A1 (en) * | 2019-07-31 | 2022-05-18 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Peptides as inhibitors of fibrotic matrix accumulation |
| JP7493945B2 (ja) * | 2020-01-28 | 2024-06-03 | ポーラ化成工業株式会社 | 培養組織の観察方法、培養方法、評価方法及び培養器具 |
| US20230265407A1 (en) * | 2020-07-02 | 2023-08-24 | Northwestern University | Human recombinant ace2-fc mutants that decouple anti-sars-cov-2 activity from cardiovascular effects |
| US20250195673A1 (en) * | 2020-11-30 | 2025-06-19 | Fred Hutchinson Cancer Center | Compositions and methods for selective depletion of target molecules |
| MX2024002895A (es) * | 2021-09-07 | 2024-06-19 | Musc Found For Res Dev | Péptidos de endostatina para el tratamiento de tumores, fibrosis y lesión pulmonar aguda. |
| EP4568993A4 (en) * | 2022-08-11 | 2026-08-05 | Technion Res & Dev Foundation | PEPTIDES TO TREAT FIBROSIS |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US750375A (en) | 1904-01-26 | Potato-digger | ||
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3832253A (en) | 1973-03-21 | 1974-08-27 | Baxter Laboratories Inc | Method of making an inflatable balloon catheter |
| US4667014A (en) | 1983-03-07 | 1987-05-19 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists |
| US7045313B1 (en) | 1982-11-30 | 2006-05-16 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant vaccinia virus containing a chimeric gene having foreign DNA flanked by vaccinia regulatory DNA |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| CA1200416A (en) | 1983-05-13 | 1986-02-11 | Societe Des Produits Nestle S.A. | Food process |
| IT1164225B (it) | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| US5093258A (en) | 1988-08-26 | 1992-03-03 | Therion Biologics Corporation | Recombinant fowlpox virus and recombination vector |
| US5217879A (en) | 1989-01-12 | 1993-06-08 | Washington University | Infectious Sindbis virus vectors |
| US6406697B1 (en) | 1989-02-23 | 2002-06-18 | Genentech, Inc. | Hybrid immunoglobulins |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| WO1991000916A2 (en) | 1989-07-06 | 1991-01-24 | The Regents Of The University Of California | Receptors for fibroblast growth factors |
| JPH04167172A (ja) | 1990-10-31 | 1992-06-15 | Nec Corp | ベクトルプロセッサ |
| US5756671A (en) | 1994-06-02 | 1998-05-26 | Mitotix, Inc. | CDC37 cell-cycle regulatory protein, and uses related thereto |
| US6080560A (en) * | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
| US5541087A (en) | 1994-09-14 | 1996-07-30 | Fuji Immunopharmaceuticals Corporation | Expression and export technology of proteins as immunofusins |
| US6165460A (en) | 1995-07-10 | 2000-12-26 | Therion Biologics Corporation | Generation of immune responses to prostate-specific antigen (PSA) |
| US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| DE19535939A1 (de) | 1995-09-27 | 1997-04-03 | Agfa Gevaert Ag | Fotografisches Material |
| WO1999029856A1 (en) | 1997-12-08 | 1999-06-17 | Beth Israel Deaconess Medical Center | Restin and methods of use thereof |
| US6218371B1 (en) | 1998-04-03 | 2001-04-17 | University Of Iowa Research Foundation | Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines |
| CA2331370A1 (en) * | 1998-06-03 | 1999-12-09 | The Children's Medical Center Corporation | Protein oligomer compositions comprising endostatin protein and methods of using the same |
| WO2000001720A2 (en) | 1998-07-02 | 2000-01-13 | President And Fellows Of Harvard College | Compositions and methods for treating papillomavirus-infected cells |
| CA2360670A1 (en) | 1999-02-05 | 2000-08-10 | Hilary Koprowski | Production of biomedical peptides and proteins in plants using transcomplementation systems |
| WO2000046380A2 (en) | 1999-02-08 | 2000-08-10 | Chiron Corporation | Fibroblast growth factor receptor-immunoglobulin fusion |
| US7692063B2 (en) * | 2002-11-12 | 2010-04-06 | Ibio, Inc. | Production of foreign nucleic acids and polypeptides in sprout systems |
| JP4874090B2 (ja) * | 2003-01-31 | 2012-02-08 | イミューノメディクス、インコーポレイテッド | 治療薬および診断薬を投与するための方法および組成物 |
| ES2531125T3 (es) | 2003-02-03 | 2015-03-10 | Ibio Inc | Sistema para la expresión de genes en plantas |
| US20060024272A1 (en) * | 2004-07-29 | 2006-02-02 | Large Scale Biology Corporation | C-terminally truncated interferon |
| WO2009003145A1 (en) * | 2007-06-26 | 2008-12-31 | University Of Miami | Antibody-endostatin fusion protein and its variants |
| US8507441B2 (en) | 2009-10-22 | 2013-08-13 | University of Pittsburgh—Of the Commonwealth Systems of Higher Education | Use of endostatin peptides for the treatment of fibrosis |
| WO2013013085A2 (en) * | 2011-07-19 | 2013-01-24 | Thrasos Innovation, Inc. | Anti-fibrotic peptides and their use in methods for treating diseases and disorders characterized by fibrosis |
| US10844392B2 (en) | 2015-06-05 | 2020-11-24 | Ibio, Inc. | Materials and methods for producing endostatin fusion polypeptides in plant cells |
-
2016
- 2016-06-03 US US15/579,690 patent/US10844392B2/en not_active Expired - Fee Related
- 2016-06-03 BR BR112017026209A patent/BR112017026209A2/pt not_active Application Discontinuation
- 2016-06-03 KR KR1020187000354A patent/KR20180033499A/ko not_active Ceased
- 2016-06-03 CN CN201680044858.5A patent/CN107849117B/zh not_active Expired - Fee Related
- 2016-06-03 AU AU2016270428A patent/AU2016270428B2/en not_active Ceased
- 2016-06-03 JP JP2018515195A patent/JP6952685B2/ja not_active Expired - Fee Related
- 2016-06-03 WO PCT/US2016/035858 patent/WO2016197018A1/en not_active Ceased
- 2016-06-03 CA CA2988299A patent/CA2988299C/en active Active
- 2016-06-03 EP EP16732386.4A patent/EP3303383A1/en not_active Withdrawn
- 2016-06-03 CN CN202210968572.3A patent/CN115925878A/zh active Pending
-
2017
- 2017-12-04 ZA ZA2017/08223A patent/ZA201708223B/en unknown
-
2020
- 2020-11-09 US US17/092,539 patent/US11912755B2/en active Active
-
2021
- 2021-02-05 AU AU2021200765A patent/AU2021200765B2/en not_active Ceased
- 2021-09-28 JP JP2021158128A patent/JP7404320B2/ja active Active
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