IT1164225B - Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione - Google Patents

Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione

Info

Publication number
IT1164225B
IT1164225B IT8321083A IT2108383A IT1164225B IT 1164225 B IT1164225 B IT 1164225B IT 8321083 A IT8321083 A IT 8321083A IT 2108383 A IT2108383 A IT 2108383A IT 1164225 B IT1164225 B IT 1164225B
Authority
IT
Italy
Prior art keywords
bpp5a
bradichina
pentapeptide
analogs
enhancing
Prior art date
Application number
IT8321083A
Other languages
English (en)
Other versions
IT8321083A0 (it
IT8321083A1 (it
Inventor
Alessandro Sisto
Antonio Silvio Verdini
Antonino Virdia
Original Assignee
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anic Spa filed Critical Anic Spa
Publication of IT8321083A0 publication Critical patent/IT8321083A0/it
Priority to IT8321083A priority Critical patent/IT1164225B/it
Priority to AT84200658T priority patent/ATE54154T1/de
Priority to EP88201526A priority patent/EP0301639A3/en
Priority to DE8484200658T priority patent/DE3482589D1/de
Priority to EP84200658A priority patent/EP0128602B1/en
Priority to CA000453932A priority patent/CA1252949A/en
Priority to US06/608,985 priority patent/US4522752A/en
Priority to AU27914/84A priority patent/AU571225B2/en
Priority to JP59094760A priority patent/JPH0635477B2/ja
Publication of IT8321083A1 publication Critical patent/IT8321083A1/it
Application granted granted Critical
Publication of IT1164225B publication Critical patent/IT1164225B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
IT8321083A 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione IT1164225B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
EP84200658A EP0128602B1 (en) 1983-05-13 1984-05-08 Retro-inverso analogues of the bradykinin potentiating peptide bpp5a and method for their preparation
EP88201526A EP0301639A3 (en) 1983-05-13 1984-05-08 Analogues of the bradykinin potentiating peptide bpp 5a and methods for their preparation
DE8484200658T DE3482589D1 (de) 1983-05-13 1984-05-08 Retro-inverse analoga des bradykinin-potentialisierenden peptids bpp-5a und verfahren zu ihrer herstellung.
AT84200658T ATE54154T1 (de) 1983-05-13 1984-05-08 Retro-inverse analoga des bradykininpotentialisierenden peptids bpp-5a und verfahren zu ihrer herstellung.
CA000453932A CA1252949A (en) 1983-05-13 1984-05-09 Retro-inverso analogues of the bradykinin potentiating peptide bpp in5a xx and method for their preparation
US06/608,985 US4522752A (en) 1983-05-13 1984-05-10 Retro-inverso analogues of the bradykinin potentiating peptide BPP5a and methods for their preparation
AU27914/84A AU571225B2 (en) 1983-05-13 1984-05-11 Retro-inverso analogues of the bradykinin potentiating peptide bpp 5a
JP59094760A JPH0635477B2 (ja) 1983-05-13 1984-05-14 ペプチド及びその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione

Publications (3)

Publication Number Publication Date
IT8321083A0 IT8321083A0 (it) 1983-05-13
IT8321083A1 IT8321083A1 (it) 1984-11-13
IT1164225B true IT1164225B (it) 1987-04-08

Family

ID=11176481

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione

Country Status (8)

Country Link
US (1) US4522752A (it)
EP (2) EP0128602B1 (it)
JP (1) JPH0635477B2 (it)
AT (1) ATE54154T1 (it)
AU (1) AU571225B2 (it)
CA (1) CA1252949A (it)
DE (1) DE3482589D1 (it)
IT (1) IT1164225B (it)

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IT1184164B (it) * 1985-03-19 1987-10-22 Eniricerche Spa Triptidi ad azione ipotensiva e procedimento per la loro sintesi
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DE04029691T1 (de) 1998-02-02 2007-11-08 Trustees Of Tufts College, Medford Verwendung von Dipetidylpeptidasehemmer zur Regulierung des Glukosemetabolismus
US6465495B1 (en) 1998-07-30 2002-10-15 Osi Pharmaceuticals, Inc. Preparation of pyridone-based phosphotyrosine mimetics and uses thereof
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US7396905B1 (en) 1999-05-21 2008-07-08 Mckeon Frank Calcipressins: endogenous inhibitors of calcineurin, uses and reagents related thereto
US20040235749A1 (en) * 1999-09-15 2004-11-25 Sylvain Chemtob G-protein coupled receptor antagonists
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US20050119454A1 (en) * 2000-01-24 2005-06-02 The Cielo Institute, Inc. Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
BR0101088A (pt) * 2001-03-19 2003-03-18 Biolab Sanus Farmaceutica Ltda Processo de isolamento e purificação de peptìdeos inibidores das vasopeptidases, com especificidade para o sìtio carboxìlico da enzima conversora da angiotensina, secretados pelas glândulas do veneno de serpentes (bpps), particularmente bothrops jararaca, ou produzidos endogenamente (evasins) possuindo ação vasodilatadora e anti-hipertensiva; processo de determinação da sequência de amido-ácidos dos peptìdios inibidores secretados pela glândula de veneno de serpentes (bpps) ou endógenos (evasins); processo de determinação da sequência de aminoácidos dos bpps por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca. processo de determinação da sequência de aminoácidos dos evasins por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca, processo de amplificação do cdna a partir das bibliotecas de cdna de pâncreas e/ou cérebro de serpentes, especificamente bothrops jararaca; processo de sìntese em fase sólida de peptìdeos inibidores das vasopeptidases com ação vasodilatadora e anti-hipertensiva, peptìdeos inibidores das vasopeptidases com ação anti-hipertensiva; utilização dos peptìdeos inibidores das vaso peptidases com ação vasodilatadora e anti-hipertensiva na obtenção de composições farmacêuticas; processo de determinação da atividade inibitória sobre as vasopeptidases e de atividade biológica sobre músculo liso, sistema cardiovascular e microcirculatório.
EP1438061B1 (en) 2001-10-03 2016-05-11 President and Fellows of Harvard College Copolymers for suppression of autoimmune diseases, and methods of use
CA2466870A1 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Methods for treating autoimmune disorders, and reagents related thereto
EP1469873A4 (en) * 2001-11-26 2007-10-03 Tufts College PEPTIDOMIMETIC INHIBITORS OF POST-PROLINE CLEAVAGE ENZYMES
US6935959B2 (en) * 2002-05-16 2005-08-30 Microsoft Corporation Use of multiple player real-time voice communications on a gaming device
US7521530B2 (en) * 2002-06-11 2009-04-21 Universite De Montreal Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
ES2616337T3 (es) 2003-12-12 2017-06-12 Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1
US7491263B2 (en) 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
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DE102004037356B4 (de) * 2004-07-30 2017-11-23 Ansaldo Energia Ip Uk Limited Wandstruktur zur Begrenzung eines Heißgaspfads
MX2007005870A (es) 2004-11-17 2007-10-10 Joanne Mclauring Composiciones que comprenden derivados de escilo-inositol y metodos para tratar trastornos de agregacion de proteinas.
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
MX2007010332A (es) 2005-02-25 2008-02-21 Univ Utah Res Found Metodos y composiciones para promover adhesion o migracion de celula endotelial.
WO2007016763A1 (en) 2005-08-05 2007-02-15 Pharmagap Inc. Peptides targeted to protein kinase c isoforms and uses thereof
US8921050B2 (en) * 2006-03-17 2014-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of diagnosing renal cell carcinoma
CN101528263B (zh) 2006-06-30 2013-01-23 Sku资产管理有限公司 用于癌症的先天性免疫方法的缀合物
JP2010523602A (ja) 2007-04-12 2010-07-15 ワラタ ファーマシューティカルズ， インコーポレイテッド 眼疾患の治療におけるシクロヘキサンヘキソール誘導体の使用
CN103864892A (zh) * 2007-06-27 2014-06-18 里兰斯坦福初级大学理事会 肽酪氨酸酶抑制剂及其应用
KR101561709B1 (ko) * 2007-06-27 2015-10-22 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 올리고펩티드 티로시나제 억제제 및 그의 용도
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JP2016536343A (ja) 2013-09-18 2016-11-24 ジェームス・クック・ユニバーシティー 抗炎症性のタンパク質及び使用方法
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CH568964A5 (it) * 1972-06-01 1975-11-14 Squibb & Sons Inc
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
IT1190891B (it) * 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
FI77875C (fi) * 1982-11-26 1989-05-10 Nyegaard & Co As Foerfarande foer framstaellning av nya terapeutiskt anvaendbara peptider.
IT1164240B (it) * 1983-05-25 1987-04-08 Anic Spa Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica
IT1206339B (it) * 1984-01-13 1989-04-14 Anic Spa Analoghi retro-invertiti esapeptidici c-terminali della sostanza p.

Also Published As

Publication number Publication date
IT8321083A0 (it) 1983-05-13
JPH0635477B2 (ja) 1994-05-11
AU2791484A (en) 1984-11-15
EP0301639A3 (en) 1989-10-18
CA1252949A (en) 1989-04-18
AU571225B2 (en) 1988-04-14
IT8321083A1 (it) 1984-11-13
JPS59212453A (ja) 1984-12-01
EP0128602A2 (en) 1984-12-19
EP0128602A3 (en) 1987-01-14
ATE54154T1 (de) 1990-07-15
EP0128602B1 (en) 1990-06-27
EP0301639A2 (en) 1989-02-01
US4522752A (en) 1985-06-11
DE3482589D1 (de) 1990-08-02

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