IT1212508B - Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori - Google Patents
Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatoriInfo
- Publication number
- IT1212508B IT1212508B IT8125753A IT2575381A IT1212508B IT 1212508 B IT1212508 B IT 1212508B IT 8125753 A IT8125753 A IT 8125753A IT 2575381 A IT2575381 A IT 2575381A IT 1212508 B IT1212508 B IT 1212508B
- Authority
- IT
- Italy
- Prior art keywords
- vasodilators
- substance
- useful
- pentas
- hexapeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8125753A IT1212508B (it) | 1981-12-22 | 1981-12-22 | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
US06/448,832 US4439360A (en) | 1981-12-22 | 1982-12-10 | Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P |
AT82201612T ATE10364T1 (de) | 1981-12-22 | 1982-12-16 | Retro-inverso analoga von c-terminalen pentaund hexapeptiden der verbindung p. |
EP82201612A EP0082568B1 (en) | 1981-12-22 | 1982-12-16 | Retro-inverso analogues of c-terminal penta and hexapeptides of substance p. |
DE8282201612T DE3261304D1 (en) | 1981-12-22 | 1982-12-16 | Retro-inverso analogues of c-terminal penta and hexapeptides of substance p. |
CA000418173A CA1249698A (en) | 1981-12-22 | 1982-12-21 | Retro-inverso analogues of c-terminal penta and hexapeptides of substance p |
JP57224103A JPS58116443A (ja) | 1981-12-22 | 1982-12-22 | 新規ペプチドおよびその製法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8125753A IT1212508B (it) | 1981-12-22 | 1981-12-22 | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8125753A0 IT8125753A0 (it) | 1981-12-22 |
IT1212508B true IT1212508B (it) | 1989-11-22 |
Family
ID=11217635
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8125753A IT1212508B (it) | 1981-12-22 | 1981-12-22 | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
Country Status (7)
Country | Link |
---|---|
US (1) | US4439360A (it) |
EP (1) | EP0082568B1 (it) |
JP (1) | JPS58116443A (it) |
AT (1) | ATE10364T1 (it) |
CA (1) | CA1249698A (it) |
DE (1) | DE3261304D1 (it) |
IT (1) | IT1212508B (it) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0118223A1 (en) * | 1983-02-07 | 1984-09-12 | Aktiebolaget Hässle | Enzyme inhibitors |
IT1164225B (it) * | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
IT1164240B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica |
IT1164239B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica |
IT1206339B (it) * | 1984-01-13 | 1989-04-14 | Anic Spa | Analoghi retro-invertiti esapeptidici c-terminali della sostanza p. |
JPS617209A (ja) * | 1984-06-20 | 1986-01-13 | Meiji Seika Kaisha Ltd | 育毛剤組成物 |
IT1178786B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Analoghi retro-inverso parzialmente modificati della neurotensina |
IT1184164B (it) * | 1985-03-19 | 1987-10-22 | Eniricerche Spa | Triptidi ad azione ipotensiva e procedimento per la loro sintesi |
IT1190389B (it) * | 1985-09-19 | 1988-02-16 | Eniricerche Spa | Esapeptidi ad attivita' ipotensiva |
IT1196500B (it) * | 1986-07-16 | 1988-11-16 | Eniricerche Spa | Derivati dell'acido malonico e metodi per la loro sintesi |
DE3783280T2 (de) * | 1986-07-16 | 1993-05-06 | Eniricerche Spa | Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten. |
US5877277A (en) * | 1987-09-24 | 1999-03-02 | Biomeasure, Inc. | Octapeptide bombesin analogs |
US6218364B1 (en) * | 1988-06-20 | 2001-04-17 | Scott L. Harbeson | Fluorinated neurokinin A antagonists |
US5830863A (en) * | 1988-06-20 | 1998-11-03 | Merrell Pharmaceuticals Inc. | Neurokinin A antagonists |
IT1228451B (it) * | 1989-02-22 | 1991-06-19 | Sclavo S P A Siena | Nuovi derivati diamminici geminali e loro impiego nelle sintesi di peptidi retro-inversi |
IE77033B1 (en) * | 1989-08-16 | 1997-11-19 | Univ Tulane | Substance P antagonists |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3862114A (en) * | 1971-11-22 | 1975-01-21 | Ici Australia Ltd | Analogs of substance p |
JPS5411293A (en) * | 1977-05-23 | 1979-01-27 | Toyo Soda Mfg Co Ltd | Recovery of protease |
-
1981
- 1981-12-22 IT IT8125753A patent/IT1212508B/it active
-
1982
- 1982-12-10 US US06/448,832 patent/US4439360A/en not_active Expired - Fee Related
- 1982-12-16 EP EP82201612A patent/EP0082568B1/en not_active Expired
- 1982-12-16 AT AT82201612T patent/ATE10364T1/de not_active IP Right Cessation
- 1982-12-16 DE DE8282201612T patent/DE3261304D1/de not_active Expired
- 1982-12-21 CA CA000418173A patent/CA1249698A/en not_active Expired
- 1982-12-22 JP JP57224103A patent/JPS58116443A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0082568A2 (en) | 1983-06-29 |
JPS58116443A (ja) | 1983-07-11 |
CA1249698A (en) | 1989-01-31 |
IT8125753A0 (it) | 1981-12-22 |
US4439360A (en) | 1984-03-27 |
DE3261304D1 (en) | 1985-01-03 |
ATE10364T1 (de) | 1984-12-15 |
EP0082568B1 (en) | 1984-11-21 |
EP0082568A3 (en) | 1983-10-26 |
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