ATE63317T1 - Teilweise modifizierte analogen von retroinverso neurotensinen. - Google Patents
Teilweise modifizierte analogen von retroinverso neurotensinen.Info
- Publication number
- ATE63317T1 ATE63317T1 AT85115888T AT85115888T ATE63317T1 AT E63317 T1 ATE63317 T1 AT E63317T1 AT 85115888 T AT85115888 T AT 85115888T AT 85115888 T AT85115888 T AT 85115888T AT E63317 T1 ATE63317 T1 AT E63317T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- neurotensins
- retroinverso
- partially modified
- modified analogues
- Prior art date
Links
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000002045 lasting effect Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT24197/84A IT1178786B (it) | 1984-12-21 | 1984-12-21 | Analoghi retro-inverso parzialmente modificati della neurotensina |
EP85115888A EP0185320B1 (de) | 1984-12-21 | 1985-12-12 | Teilweise modifizierte Analogen von retroinverso Neurotensinen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE63317T1 true ATE63317T1 (de) | 1991-05-15 |
Family
ID=11212494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85115888T ATE63317T1 (de) | 1984-12-21 | 1985-12-12 | Teilweise modifizierte analogen von retroinverso neurotensinen. |
Country Status (6)
Country | Link |
---|---|
US (1) | US4716149A (de) |
EP (1) | EP0185320B1 (de) |
JP (1) | JPS61155396A (de) |
AT (1) | ATE63317T1 (de) |
DE (1) | DE3582786D1 (de) |
IT (1) | IT1178786B (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1190389B (it) * | 1985-09-19 | 1988-02-16 | Eniricerche Spa | Esapeptidi ad attivita' ipotensiva |
ES2052517T3 (es) * | 1986-07-16 | 1994-07-16 | Eniricerche Spa | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
US5807979A (en) * | 1988-04-08 | 1998-09-15 | The Scripps Research Institute | Synthetic, three-dimensionally stabilized polypeptide mimics of HIV |
AU3534989A (en) * | 1988-04-08 | 1989-11-03 | Scripps Clinic And Research Foundation | Polypeptides stabilized by covalent hydrogen bond replacements |
US5374621A (en) * | 1991-09-13 | 1994-12-20 | Regents Of The University Of California | Neurotensin method for inhibiting vascular leakage |
WO2019156565A1 (en) | 2018-02-12 | 2019-08-15 | Fast Forward Pharmaceuticals B.V. | Improved antagonistic anti-human cd40 monoclonal antibodies |
WO2020102454A1 (en) | 2018-11-13 | 2020-05-22 | Regents Of The University Of Minnesota | Cd40 targeted peptides and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3929756A (en) * | 1973-11-21 | 1975-12-30 | Univ Brandeis | Synthetically produced tridecapeptide having the same activity as the hypothalamic substance, neurotensin |
US4110321A (en) * | 1976-07-12 | 1978-08-29 | Folkers Karl | Synthetic tridecapeptide [Gln4 ]-neurotensin having hormonal activity |
US4331661A (en) * | 1980-10-03 | 1982-05-25 | The Salk Institute For Biological Studies | Bombesin analogs |
IT1212508B (it) * | 1981-12-22 | 1989-11-22 | Anic Spa | Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori |
IT1190891B (it) * | 1982-06-24 | 1988-02-24 | Anic Spa | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
US4439359A (en) * | 1982-07-02 | 1984-03-27 | Merck & Co., Inc. | Cyclic octapeptide analogs of neurotensin |
US4613586A (en) * | 1984-04-19 | 1986-09-23 | Board Of Trustees Of The Leland Stanford Junior University | Gastrin releasing peptide-like peptides |
-
1984
- 1984-12-21 IT IT24197/84A patent/IT1178786B/it active
-
1985
- 1985-12-12 DE DE8585115888T patent/DE3582786D1/de not_active Expired - Lifetime
- 1985-12-12 EP EP85115888A patent/EP0185320B1/de not_active Expired - Lifetime
- 1985-12-12 AT AT85115888T patent/ATE63317T1/de not_active IP Right Cessation
- 1985-12-13 US US06/808,617 patent/US4716149A/en not_active Expired - Fee Related
- 1985-12-20 JP JP60287645A patent/JPS61155396A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0185320A2 (de) | 1986-06-25 |
US4716149A (en) | 1987-12-29 |
EP0185320B1 (de) | 1991-05-08 |
IT8424197A0 (it) | 1984-12-21 |
DE3582786D1 (de) | 1991-06-13 |
EP0185320A3 (en) | 1988-03-16 |
IT1178786B (it) | 1987-09-16 |
JPS61155396A (ja) | 1986-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |