ATE63317T1 - Teilweise modifizierte analogen von retroinverso neurotensinen. - Google Patents

Teilweise modifizierte analogen von retroinverso neurotensinen.

Info

Publication number
ATE63317T1
ATE63317T1 AT85115888T AT85115888T ATE63317T1 AT E63317 T1 ATE63317 T1 AT E63317T1 AT 85115888 T AT85115888 T AT 85115888T AT 85115888 T AT85115888 T AT 85115888T AT E63317 T1 ATE63317 T1 AT E63317T1
Authority
AT
Austria
Prior art keywords
sub
neurotensins
retroinverso
partially modified
modified analogues
Prior art date
Application number
AT85115888T
Other languages
English (en)
Inventor
Fabio Bonelli
Antonello Pessi
Antonio Silvio Verdini
Original Assignee
Eniricerche Spa
Sclavo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eniricerche Spa, Sclavo Spa filed Critical Eniricerche Spa
Application granted granted Critical
Publication of ATE63317T1 publication Critical patent/ATE63317T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT85115888T 1984-12-21 1985-12-12 Teilweise modifizierte analogen von retroinverso neurotensinen. ATE63317T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT24197/84A IT1178786B (it) 1984-12-21 1984-12-21 Analoghi retro-inverso parzialmente modificati della neurotensina
EP85115888A EP0185320B1 (de) 1984-12-21 1985-12-12 Teilweise modifizierte Analogen von retroinverso Neurotensinen

Publications (1)

Publication Number Publication Date
ATE63317T1 true ATE63317T1 (de) 1991-05-15

Family

ID=11212494

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85115888T ATE63317T1 (de) 1984-12-21 1985-12-12 Teilweise modifizierte analogen von retroinverso neurotensinen.

Country Status (6)

Country Link
US (1) US4716149A (de)
EP (1) EP0185320B1 (de)
JP (1) JPS61155396A (de)
AT (1) ATE63317T1 (de)
DE (1) DE3582786D1 (de)
IT (1) IT1178786B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
DE3783280T2 (de) * 1986-07-16 1993-05-06 Eniricerche Spa Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
WO1989009783A1 (en) * 1988-04-08 1989-10-19 Scripps Clinic And Research Foundation Polypeptides stabilized by covalent hydrogen bond replacements
US5807979A (en) * 1988-04-08 1998-09-15 The Scripps Research Institute Synthetic, three-dimensionally stabilized polypeptide mimics of HIV
US5374621A (en) * 1991-09-13 1994-12-20 Regents Of The University Of California Neurotensin method for inhibiting vascular leakage
EP3229586B1 (de) 2014-12-10 2025-07-30 Regents of the University of Minnesota Genetisch modifizierte zellen, gewebe und organe zur behandlung von krankheiten
KR20200141986A (ko) 2018-02-12 2020-12-21 다이어비티스-프리, 인크. 개선된 길항성 항-인간 cd40 단클론 항체
WO2020102454A1 (en) 2018-11-13 2020-05-22 Regents Of The University Of Minnesota Cd40 targeted peptides and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929756A (en) * 1973-11-21 1975-12-30 Univ Brandeis Synthetically produced tridecapeptide having the same activity as the hypothalamic substance, neurotensin
US4110321A (en) * 1976-07-12 1978-08-29 Folkers Karl Synthetic tridecapeptide [Gln4 ]-neurotensin having hormonal activity
US4331661A (en) * 1980-10-03 1982-05-25 The Salk Institute For Biological Studies Bombesin analogs
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
IT1190891B (it) * 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
US4439359A (en) * 1982-07-02 1984-03-27 Merck & Co., Inc. Cyclic octapeptide analogs of neurotensin
US4613586A (en) * 1984-04-19 1986-09-23 Board Of Trustees Of The Leland Stanford Junior University Gastrin releasing peptide-like peptides

Also Published As

Publication number Publication date
DE3582786D1 (de) 1991-06-13
JPS61155396A (ja) 1986-07-15
US4716149A (en) 1987-12-29
EP0185320A2 (de) 1986-06-25
EP0185320A3 (en) 1988-03-16
EP0185320B1 (de) 1991-05-08
IT8424197A0 (it) 1984-12-21
IT1178786B (it) 1987-09-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee