IT1190891B - Metodo per la sintesi in fase solida di polipeptidi retroinvertiti - Google Patents

Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Info

Publication number
IT1190891B
IT1190891B IT22046/82A IT2204682A IT1190891B IT 1190891 B IT1190891 B IT 1190891B IT 22046/82 A IT22046/82 A IT 22046/82A IT 2204682 A IT2204682 A IT 2204682A IT 1190891 B IT1190891 B IT 1190891B
Authority
IT
Italy
Prior art keywords
phase synthesis
polypeptides
bis
retroinverted
solid phase
Prior art date
Application number
IT22046/82A
Other languages
English (en)
Other versions
IT8222046A0 (it
Inventor
Antonello Pessi
Massimo Pinori
Antonio Silvio Verdini
Giuseppe Claudio Viscomi
Original Assignee
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anic Spa filed Critical Anic Spa
Priority to IT22046/82A priority Critical patent/IT1190891B/it
Publication of IT8222046A0 publication Critical patent/IT8222046A0/it
Priority to EP83200889A priority patent/EP0097994B1/en
Priority to AT83200889T priority patent/ATE30033T1/de
Priority to DE8383200889T priority patent/DE3373908D1/de
Application granted granted Critical
Publication of IT1190891B publication Critical patent/IT1190891B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
IT22046/82A 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti IT1190891B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
EP83200889A EP0097994B1 (en) 1982-06-24 1983-06-17 Method for the solid-phase synthesis of retro-inverso polypeptides
AT83200889T ATE30033T1 (de) 1982-06-24 1983-06-17 Verfahren zur herstellung von retro-inverso polypeptiden in fester phase.
DE8383200889T DE3373908D1 (en) 1982-06-24 1983-06-17 Method for the solid-phase synthesis of retro-inverso polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Publications (2)

Publication Number Publication Date
IT8222046A0 IT8222046A0 (it) 1982-06-24
IT1190891B true IT1190891B (it) 1988-02-24

Family

ID=11190672

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Country Status (4)

Country Link
EP (1) EP0097994B1 (it)
AT (1) ATE30033T1 (it)
DE (1) DE3373908D1 (it)
IT (1) IT1190891B (it)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0118223A1 (en) * 1983-02-07 1984-09-12 Aktiebolaget Hässle Enzyme inhibitors
IT1164225B (it) * 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
IT1164240B (it) * 1983-05-25 1987-04-08 Anic Spa Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica
US4668476A (en) * 1984-03-23 1987-05-26 Applied Biosystems, Inc. Automated polypeptide synthesis apparatus
IT1178789B (it) * 1984-12-21 1987-09-16 Assorenti Peptidi retro-invertiti analoghi del potenziatore della bradichinina bpp 5a
IT1178786B (it) * 1984-12-21 1987-09-16 Assorenti Analoghi retro-inverso parzialmente modificati della neurotensina
IT1184317B (it) * 1985-02-05 1987-10-28 Eniricerche Spa Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
IT1188206B (it) * 1985-11-28 1988-01-07 Eniricerche Spa Procedimento per la sintesi in fase solida di peptidi in cui almeno un legame ammidico e' retroinvertito
GB2187461A (en) * 1986-02-03 1987-09-09 Medical Res Council Monitoring method for the synthesis of a linear of amino acid residues
DE3783280T2 (de) * 1986-07-16 1993-05-06 Eniricerche Spa Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
IT1196500B (it) * 1986-07-16 1988-11-16 Eniricerche Spa Derivati dell'acido malonico e metodi per la loro sintesi
AU667578B2 (en) * 1992-08-27 1996-03-28 Deakin Research Limited Retro-, inverso-, and retro-inverso synthetic peptide analogues
FR2717081B1 (fr) * 1994-03-14 1996-06-21 Centre Nat Rech Scient Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro.
US6916904B2 (en) 2002-04-24 2005-07-12 Zolaris Biosciences, Llc Inhibition of immune complex formation
AU2005221187B2 (en) 2004-03-10 2011-09-01 Trinity Therapeutics, Inc. Method for inhibiting immune complex formation in a subjetc
WO2008124768A1 (en) 2007-04-09 2008-10-16 The General Hospital Corporation Hemojuvelin fusion proteins and uses thereof
TWI573806B (zh) 2008-04-17 2017-03-11 巴克斯歐塔公司 生物活性胜肽
EP2320924B1 (en) 2008-07-18 2015-03-11 Trinity Therapeutics, Inc. A polypeptide for use in treating dengue virus infections
EP3406267A1 (en) 2011-03-25 2018-11-28 Children's Medical Center Corporation Lin28-mediated control of let-7 biogenesis
WO2012170969A2 (en) 2011-06-10 2012-12-13 Biogen Idec Ma Inc. Pro-coagulant compounds and methods of use thereof
EP3381461B1 (en) 2012-01-09 2021-03-10 Serpin Pharma, LLC Peptides and methods of using same
ES2651113T3 (es) 2012-06-25 2018-01-24 The Brigham And Women's Hospital, Inc. Tratamientos terapéuticos dirigidos
EP2968470B1 (en) 2013-03-12 2020-10-28 The General Hospital Corporation Modified mullerian inhibiting substance (mis) proteins and uses thereof for the treatment of diseases
EP3065769A4 (en) 2013-11-08 2017-05-31 Biogen MA Inc. Procoagulant fusion compound
EP3194446B1 (en) 2014-09-18 2022-10-26 Cedars-Sinai Medical Center Compositions and methods for treating fibrosis
EP3285795B1 (en) 2015-04-22 2022-11-16 Cedars-Sinai Medical Center Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes and obesity
AU2016317726B2 (en) 2015-08-28 2022-05-26 Serpin Pharma, Llc Methods for treatment of diseases
WO2017075451A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
EP3368689B1 (en) 2015-10-28 2020-06-17 The Broad Institute, Inc. Composition for modulating immune responses by use of immune cell gene signature
WO2017075465A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
WO2018049025A2 (en) 2016-09-07 2018-03-15 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses
BR112021004404A2 (pt) 2018-09-10 2021-08-03 Lung Therapeutics, Inc. fragmentos de peptídeos modificados da proteína cav-1 e o uso destes no tratamento de fibrose
US20230374153A1 (en) 2022-04-13 2023-11-23 Paradigm Immunoterapeutics, Inc. METHODS OF PREVENTING OR TREATING INFECTION BY RESPIRATORY VIRUSES INCLUDING SARS-CoV-2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862114A (en) * 1971-11-22 1975-01-21 Ici Australia Ltd Analogs of substance p

Also Published As

Publication number Publication date
EP0097994B1 (en) 1987-09-30
DE3373908D1 (en) 1987-11-05
EP0097994A3 (en) 1985-11-27
IT8222046A0 (it) 1982-06-24
EP0097994A2 (en) 1984-01-11
ATE30033T1 (de) 1987-10-15

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