IT8222046A0 - Metodo per la sintesi in fase solida di polipeptidi retroinvertiti - Google Patents

Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Info

Publication number
IT8222046A0
IT8222046A0 IT8222046A IT2204682A IT8222046A0 IT 8222046 A0 IT8222046 A0 IT 8222046A0 IT 8222046 A IT8222046 A IT 8222046A IT 2204682 A IT2204682 A IT 2204682A IT 8222046 A0 IT8222046 A0 IT 8222046A0
Authority
IT
Italy
Prior art keywords
polypeptides
inverted
solid phase
phase synthesis
synthesis
Prior art date
Application number
IT8222046A
Other languages
English (en)
Other versions
IT1190891B (it
Inventor
Pessi Antonello
Pinori Massimo
Verdini Antonio Silvio
Viscomi Giuseppe Claudio
Original Assignee
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anic Spa filed Critical Anic Spa
Priority to IT22046/82A priority Critical patent/IT1190891B/it
Publication of IT8222046A0 publication Critical patent/IT8222046A0/it
Priority to AT83200889T priority patent/ATE30033T1/de
Priority to DE8383200889T priority patent/DE3373908D1/de
Priority to EP83200889A priority patent/EP0097994B1/en
Application granted granted Critical
Publication of IT1190891B publication Critical patent/IT1190891B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT22046/82A 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti IT1190891B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
AT83200889T ATE30033T1 (de) 1982-06-24 1983-06-17 Verfahren zur herstellung von retro-inverso polypeptiden in fester phase.
DE8383200889T DE3373908D1 (en) 1982-06-24 1983-06-17 Method for the solid-phase synthesis of retro-inverso polypeptides
EP83200889A EP0097994B1 (en) 1982-06-24 1983-06-17 Method for the solid-phase synthesis of retro-inverso polypeptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Publications (2)

Publication Number Publication Date
IT8222046A0 true IT8222046A0 (it) 1982-06-24
IT1190891B IT1190891B (it) 1988-02-24

Family

ID=11190672

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22046/82A IT1190891B (it) 1982-06-24 1982-06-24 Metodo per la sintesi in fase solida di polipeptidi retroinvertiti

Country Status (4)

Country Link
EP (1) EP0097994B1 (it)
AT (1) ATE30033T1 (it)
DE (1) DE3373908D1 (it)
IT (1) IT1190891B (it)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU573735B2 (en) * 1983-02-07 1988-06-23 Aktiebolaget Hassle Peptide analogue enzyme inhibitors
IT1164225B (it) * 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
IT1164240B (it) * 1983-05-25 1987-04-08 Anic Spa Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica
US4668476A (en) * 1984-03-23 1987-05-26 Applied Biosystems, Inc. Automated polypeptide synthesis apparatus
IT1178789B (it) * 1984-12-21 1987-09-16 Assorenti Peptidi retro-invertiti analoghi del potenziatore della bradichinina bpp 5a
IT1178786B (it) * 1984-12-21 1987-09-16 Assorenti Analoghi retro-inverso parzialmente modificati della neurotensina
IT1184317B (it) * 1985-02-05 1987-10-28 Eniricerche Spa Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
IT1188206B (it) * 1985-11-28 1988-01-07 Eniricerche Spa Procedimento per la sintesi in fase solida di peptidi in cui almeno un legame ammidico e' retroinvertito
GB2187461A (en) * 1986-02-03 1987-09-09 Medical Res Council Monitoring method for the synthesis of a linear of amino acid residues
EP0253190B1 (en) * 1986-07-16 1992-12-30 ENIRICERCHE S.p.A. Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them
IT1196500B (it) * 1986-07-16 1988-11-16 Eniricerche Spa Derivati dell'acido malonico e metodi per la loro sintesi
US6261569B1 (en) 1992-08-27 2001-07-17 Deakin Research Limited Retro-, inverso- and retro-inverso synthetic peptide analogues
FR2717081B1 (fr) * 1994-03-14 1996-06-21 Centre Nat Rech Scient Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro.
US6916904B2 (en) 2002-04-24 2005-07-12 Zolaris Biosciences, Llc Inhibition of immune complex formation
EP1730170B1 (en) 2004-03-10 2020-02-19 Trinity Therapeutics, Inc. Method for inhibiting immune complex formation in a subject
US8895002B2 (en) 2007-04-09 2014-11-25 The General Hospital Corporation Hemojuvelin fusion proteins and uses thereof
TWI541020B (zh) 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽
SG10201500597YA (en) 2008-07-18 2015-04-29 Trinity Therapeutics Inc Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome
WO2012135081A2 (en) 2011-03-25 2012-10-04 Children's Medical Center Corporation Lin28-mediated control of let-7 biogenesis
PL2717898T3 (pl) 2011-06-10 2019-06-28 Bioverativ Therapeutics Inc. Związki o działaniu prokoagulacyjnym i sposoby ich stosowania
AU2013208293B2 (en) 2012-01-09 2017-08-10 Serpin Pharma, Llc Peptides and methods of using same
PT2864360T (pt) 2012-06-25 2018-01-05 The Brigham And Women`S Hospital Inc Terapêuticas dirigidas ao alvo
KR20160029731A (ko) 2013-03-12 2016-03-15 더 제너럴 하스피탈 코포레이션 변형된 뮐러관 억제 물질(mis) 단백질 및 질환 치료를 위한 그 용도
EP3065769A4 (en) 2013-11-08 2017-05-31 Biogen MA Inc. Procoagulant fusion compound
WO2016044707A1 (en) 2014-09-18 2016-03-24 Cedars-Sinai Medical Center Compositions and methods for treating fibrosis
US20180110823A1 (en) 2015-04-22 2018-04-26 Cedars-Sinai Medical Center Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes
CN111909258B (zh) 2015-08-28 2021-09-17 赛品制药有限责任公司 用于疾病治疗的方法
WO2017075465A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
WO2017075451A1 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
WO2017075478A2 (en) 2015-10-28 2017-05-04 The Broad Institute Inc. Compositions and methods for evaluating and modulating immune responses by use of immune cell gene signatures
US20190262399A1 (en) 2016-09-07 2019-08-29 The Broad Institute, Inc. Compositions and methods for evaluating and modulating immune responses
AU2019339264A1 (en) 2018-09-10 2021-03-11 Board Of Regents, The University Of Texas System Dry powder formulation of caveolin-1 peptides and methods of use thereof
EP3849580A4 (en) 2018-09-10 2022-06-15 Lung Therapeutics, Inc. MODIFIED PEPTIDE FRAGMENTS OF CAV-1 PROTEIN AND THEIR USE IN THE TREATMENT OF FIBROSIS
WO2023200887A1 (en) 2022-04-13 2023-10-19 Paradigm Immunotherapeutics, Inc. Methods of preventing or treating infection by respiratory viruses including sars-cov-2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862114A (en) * 1971-11-22 1975-01-21 Ici Australia Ltd Analogs of substance p

Also Published As

Publication number Publication date
EP0097994B1 (en) 1987-09-30
EP0097994A2 (en) 1984-01-11
IT1190891B (it) 1988-02-24
EP0097994A3 (en) 1985-11-27
ATE30033T1 (de) 1987-10-15
DE3373908D1 (en) 1987-11-05

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