DK162218C - 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner - Google Patents

3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner

Info

Publication number
DK162218C
DK162218C DK621589A DK621589A DK162218C DK 162218 C DK162218 C DK 162218C DK 621589 A DK621589 A DK 621589A DK 621589 A DK621589 A DK 621589A DK 162218 C DK162218 C DK 162218C
Authority
DK
Denmark
Prior art keywords
carboxamidopyridazines
pyridazines
oxo
cyano
unknown
Prior art date
Application number
DK621589A
Other languages
English (en)
Other versions
DK621589D0 (da
DK621589A (da
DK162218B (da
Inventor
Kathleen Biziere
Jean-Paul Kan
Camille-Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8301366A external-priority patent/FR2540115B1/fr
Priority claimed from FR8318433A external-priority patent/FR2555178B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK621589D0 publication Critical patent/DK621589D0/da
Publication of DK621589A publication Critical patent/DK621589A/da
Publication of DK162218B publication Critical patent/DK162218B/da
Application granted granted Critical
Publication of DK162218C publication Critical patent/DK162218C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK621589A 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner DK162218C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8301366A FR2540115B1 (fr) 1983-01-28 1983-01-28 Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR8301366 1983-01-28
FR8318433 1983-11-18
FR8318433A FR2555178B1 (fr) 1983-11-18 1983-11-18 Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant

Publications (4)

Publication Number Publication Date
DK621589D0 DK621589D0 (da) 1989-12-08
DK621589A DK621589A (da) 1989-12-08
DK162218B DK162218B (da) 1991-09-30
DK162218C true DK162218C (da) 1992-03-02

Family

ID=26223263

Family Applications (3)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem
DK621589A DK162218C (da) 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner
DK621689A DK162219C (da) 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK621689A DK162219C (da) 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner

Country Status (25)

Country Link
US (2) US4565814A (da)
EP (1) EP0116494B1 (da)
KR (1) KR910000639B1 (da)
AU (1) AU566352B2 (da)
CA (1) CA1218655A (da)
CS (1) CS274405B2 (da)
DD (1) DD215542A5 (da)
DE (1) DE3469026D1 (da)
DK (3) DK159969C (da)
ES (1) ES8500253A1 (da)
FI (1) FI77453C (da)
GR (1) GR81682B (da)
HU (1) HU192975B (da)
IE (1) IE56750B1 (da)
IL (1) IL70755A (da)
MA (1) MA20019A1 (da)
NO (1) NO840329L (da)
NZ (1) NZ206957A (da)
OA (1) OA07645A (da)
PH (1) PH21476A (da)
PL (1) PL143994B1 (da)
PT (1) PT77994B (da)
SG (1) SG9389G (da)
SU (1) SU1274623A3 (da)
YU (1) YU14184A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3672536D1 (de) * 1985-06-14 1990-08-16 Lilly Co Eli Fungizide pyridazine.
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
RU2224520C2 (ru) 1998-08-20 2004-02-27 Тояма Кемикал Ко., Лтд. Азотсодержащие гетероциклические производные карбоксамида или их соли и противовирусные средства, включающие их
DK1144388T3 (da) 1999-01-22 2010-05-25 Elan Pharm Inc Acyl-derivater, som behandler VLA-4-relaterede lidelser
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
AU2005260102A1 (en) * 2004-05-08 2006-01-12 Novartis International Pharmaceutical Ltd. 3-aryl-5,6-disubstituted pyridazines
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
KR20080059268A (ko) 2005-09-29 2008-06-26 엘란 파마슈티칼스, 인크. Vla-4에 의해 매개되는 백혈구 부착을 억제하는피리미디닐 아미드 화합물
ATE502031T1 (de) 2005-09-29 2011-04-15 Elan Pharm Inc Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren
CA2643838A1 (en) 2006-02-27 2007-09-07 Elan Pharmaceuticals, Inc. Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
CA2760151A1 (en) 2009-04-27 2010-11-04 Elan Pharmaceuticals, Inc. Pyridinone antagonists of alpha-4 integrins
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
EP2560488B1 (en) 2010-04-23 2015-10-28 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant

Also Published As

Publication number Publication date
PL143994B1 (en) 1988-04-30
DK159969B (da) 1991-01-07
FI77453B (fi) 1988-11-30
DK621589D0 (da) 1989-12-08
FI840349A0 (fi) 1984-01-27
US4565814A (en) 1986-01-21
GR81682B (da) 1984-12-12
ES529108A0 (es) 1984-10-01
DK25984D0 (da) 1984-01-20
PH21476A (en) 1987-10-28
KR840007587A (ko) 1984-12-08
IL70755A (en) 1987-03-31
NO840329L (no) 1984-07-30
FI77453C (fi) 1989-03-10
AU2372884A (en) 1984-08-02
DK162219C (da) 1992-03-02
FI840349A (fi) 1984-07-29
SU1274623A3 (ru) 1986-11-30
AU566352B2 (en) 1987-10-15
US4631280A (en) 1986-12-23
DD215542A5 (de) 1984-11-14
IE840148L (en) 1984-07-28
MA20019A1 (fr) 1984-10-01
IL70755A0 (en) 1984-04-30
ES8500253A1 (es) 1984-10-01
DK621589A (da) 1989-12-08
PL245932A1 (en) 1985-05-21
YU14184A (en) 1986-10-31
DK621689D0 (da) 1989-12-08
CA1218655A (en) 1987-03-03
DK162219B (da) 1991-09-30
DK621689A (da) 1989-12-08
CS61484A2 (en) 1990-09-12
NZ206957A (en) 1987-06-30
DK25984A (da) 1984-07-29
HU192975B (en) 1987-08-28
CS274405B2 (en) 1991-04-11
DE3469026D1 (en) 1988-03-03
OA07645A (fr) 1985-05-23
EP0116494B1 (fr) 1988-01-27
KR910000639B1 (ko) 1991-01-31
EP0116494A1 (fr) 1984-08-22
IE56750B1 (en) 1991-12-04
SG9389G (en) 1989-07-07
PT77994A (fr) 1984-02-01
DK159969C (da) 1991-05-27
DK162218B (da) 1991-09-30
PT77994B (fr) 1986-04-10

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