DK621589D0 - Mellemprodukter til syntese af hidtil ukendte 4-cyanopyridaziner - Google Patents

Mellemprodukter til syntese af hidtil ukendte 4-cyanopyridaziner

Info

Publication number
DK621589D0
DK621589D0 DK621589A DK621589A DK621589D0 DK 621589 D0 DK621589 D0 DK 621589D0 DK 621589 A DK621589 A DK 621589A DK 621589 A DK621589 A DK 621589A DK 621589 D0 DK621589 D0 DK 621589D0
Authority
DK
Denmark
Prior art keywords
unknown
cyanopyridazines
intermediates
synthesis
unknown unknown
Prior art date
Application number
DK621589A
Other languages
English (en)
Other versions
DK162218C (da
DK621589A (da
DK162218B (da
Inventor
Kathleen Biziere
Jean-Paul Kan
Camille-Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8301366A external-priority patent/FR2540115B1/fr
Priority claimed from FR8318433A external-priority patent/FR2555178B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK621589D0 publication Critical patent/DK621589D0/da
Publication of DK621589A publication Critical patent/DK621589A/da
Publication of DK162218B publication Critical patent/DK162218B/da
Application granted granted Critical
Publication of DK162218C publication Critical patent/DK162218C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK621589A 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner DK162218C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8301366 1983-01-28
FR8301366A FR2540115B1 (fr) 1983-01-28 1983-01-28 Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR8318433 1983-11-18
FR8318433A FR2555178B1 (fr) 1983-11-18 1983-11-18 Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant

Publications (4)

Publication Number Publication Date
DK621589D0 true DK621589D0 (da) 1989-12-08
DK621589A DK621589A (da) 1989-12-08
DK162218B DK162218B (da) 1991-09-30
DK162218C DK162218C (da) 1992-03-02

Family

ID=26223263

Family Applications (3)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem
DK621689A DK162219C (da) 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner
DK621589A DK162218C (da) 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem
DK621689A DK162219C (da) 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner

Country Status (25)

Country Link
US (2) US4565814A (da)
EP (1) EP0116494B1 (da)
KR (1) KR910000639B1 (da)
AU (1) AU566352B2 (da)
CA (1) CA1218655A (da)
CS (1) CS274405B2 (da)
DD (1) DD215542A5 (da)
DE (1) DE3469026D1 (da)
DK (3) DK159969C (da)
ES (1) ES8500253A1 (da)
FI (1) FI77453C (da)
GR (1) GR81682B (da)
HU (1) HU192975B (da)
IE (1) IE56750B1 (da)
IL (1) IL70755A (da)
MA (1) MA20019A1 (da)
NO (1) NO840329L (da)
NZ (1) NZ206957A (da)
OA (1) OA07645A (da)
PH (1) PH21476A (da)
PL (1) PL143994B1 (da)
PT (1) PT77994B (da)
SG (1) SG9389G (da)
SU (1) SU1274623A3 (da)
YU (1) YU14184A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
ES8707201A1 (es) * 1985-06-14 1987-07-16 Lilly Co Eli Un procedimiento para la preparacion de una serie de piridazinas
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
EP1112743B1 (en) * 1998-08-20 2007-10-24 Toyama Chemical Co., Ltd. Nitrogenous heterocyclic carboxamide derivatives or salt thereof as antiviral agents
IL143929A0 (en) 1999-01-22 2002-04-21 Elan Pharm Inc Acyl derivatives which treat vla-4 related disorders
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
CN1984904A (zh) * 2004-05-08 2007-06-20 神经能质公司 3-芳基-5,6-二取代哒嗪
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
EA015388B1 (ru) 2005-09-29 2011-08-30 Элан Фамэсьютикэлс, Инк. ПИРИМИДИНИЛАМИДНЫЕ СОЕДИНЕНИЯ (ВАРИАНТЫ), ВКЛЮЧАЮЩАЯ ИХ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ, ОПОСРЕДОВАННОГО α4-ИНТЕГРИНАМИ
CA2624524C (en) 2005-09-29 2014-07-08 Elan Pharmaceuticals, Inc. Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4
NZ570679A (en) 2006-02-27 2011-01-28 Elan Pharm Inc Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated By VLA-4
CN102459179A (zh) 2009-04-27 2012-05-16 艾伦药物公司 α-4整联蛋白的吡啶酮拮抗剂
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
WO2011133920A1 (en) 2010-04-23 2011-10-27 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant

Also Published As

Publication number Publication date
EP0116494B1 (fr) 1988-01-27
PH21476A (en) 1987-10-28
DK621689D0 (da) 1989-12-08
DK621689A (da) 1989-12-08
GR81682B (da) 1984-12-12
OA07645A (fr) 1985-05-23
CS61484A2 (en) 1990-09-12
PL143994B1 (en) 1988-04-30
SU1274623A3 (ru) 1986-11-30
YU14184A (en) 1986-10-31
DK162219C (da) 1992-03-02
ES529108A0 (es) 1984-10-01
KR840007587A (ko) 1984-12-08
FI840349A0 (fi) 1984-01-27
IE56750B1 (en) 1991-12-04
SG9389G (en) 1989-07-07
CS274405B2 (en) 1991-04-11
DD215542A5 (de) 1984-11-14
NZ206957A (en) 1987-06-30
DK25984A (da) 1984-07-29
EP0116494A1 (fr) 1984-08-22
FI840349A (fi) 1984-07-29
ES8500253A1 (es) 1984-10-01
FI77453C (fi) 1989-03-10
DK25984D0 (da) 1984-01-20
DK162219B (da) 1991-09-30
KR910000639B1 (ko) 1991-01-31
DE3469026D1 (en) 1988-03-03
US4631280A (en) 1986-12-23
NO840329L (no) 1984-07-30
DK162218C (da) 1992-03-02
AU566352B2 (en) 1987-10-15
PT77994B (fr) 1986-04-10
MA20019A1 (fr) 1984-10-01
HU192975B (en) 1987-08-28
CA1218655A (en) 1987-03-03
DK159969B (da) 1991-01-07
AU2372884A (en) 1984-08-02
PT77994A (fr) 1984-02-01
IE840148L (en) 1984-07-28
DK621589A (da) 1989-12-08
IL70755A (en) 1987-03-31
PL245932A1 (en) 1985-05-21
IL70755A0 (en) 1984-04-30
US4565814A (en) 1986-01-21
DK159969C (da) 1991-05-27
DK162218B (da) 1991-09-30
FI77453B (fi) 1988-11-30

Similar Documents

Publication Publication Date Title
DK65882A (da) Fremgangsmaade til fremstilling af substituerede phosphonamider
DK279484D0 (da) Fremgangsmaade til rensning af roeggas
DK621689D0 (da) Mellemprodukter til syntese af hidtil ukendte 4-cyanopyridaziner
DK276582A (da) Fremgangsmaade til fremstilling af cephemderivater
DK129085D0 (da) Fremgangsmaade til fremstilling af proteiner
DK63683A (da) Fremgangsmaade til fremstilling af cephemderivater
DK335882A (da) Fremgangsmaade til fremstilling af cephemderivater
DK427083A (da) Fremgangsmaade til fremstilling af cephemderivater
DK46781A (da) Fremgangsmaade til fremstilling af antirhinovirusmidler
DK480482A (da) Fremgangsmaade til syntese af alfa-chlormethylchlorformiat
DK331282A (da) Fremgangsmaade til fremstilling af hidtil ukendte benztriazoler
DK287484A (da) Fremgangsmaade til fremstilling af acetaldehyd
DE3480701D1 (de) Kontrollierte einleitung der chromdioxydsynthese.
DK153841C (da) Fremgangsmaade til fremstilling af ranitidin
DK12581A (da) Fremgangsmaade til fremstilling af kijanimicin
DK469785D0 (da) Fremgangsmaade til fremstilling af aldehyder
DK175290A (da) Fremgangsmaade til fremstilling af azetidinoner
DK296883D0 (da) Fremgangsmade til fremstilling af eburnanoximaetere
DK559786A (da) Mellemprodukter til fremstilling af beta-lactamantibiotika
DK151796C (da) Fremgangsmaade til fremstilling af cyclopentenoloner
DK157874C (da) Fremgangsmaade til fremstilling af azinomethylrifamyciner
DK425482A (da) Fremgangsmaade til fremstilling af amider
DK468883D0 (da) Fremgangsmade til fremstilling af fugtabsorberende genstande
DK186984D0 (da) Fremgangsmaade til fremstilling af 3-benzothienylglycin-forbindelser
NO850080L (no) Mellomprodukter for fremstilling av cefalosporinforbindelser

Legal Events

Date Code Title Description
PBP Patent lapsed