DK162219C - 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner - Google Patents

3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner

Info

Publication number
DK162219C
DK162219C DK621689A DK621689A DK162219C DK 162219 C DK162219 C DK 162219C DK 621689 A DK621689 A DK 621689A DK 621689 A DK621689 A DK 621689A DK 162219 C DK162219 C DK 162219C
Authority
DK
Denmark
Prior art keywords
cyanopyridazines
chlor
unknown
synthesis
Prior art date
Application number
DK621689A
Other languages
English (en)
Other versions
DK621689D0 (da
DK621689A (da
DK162219B (da
Inventor
Kathleen Biziere
Jean-Paul Kan
Camille-Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8301366A external-priority patent/FR2540115B1/fr
Priority claimed from FR8318433A external-priority patent/FR2555178B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK621689D0 publication Critical patent/DK621689D0/da
Publication of DK621689A publication Critical patent/DK621689A/da
Publication of DK162219B publication Critical patent/DK162219B/da
Application granted granted Critical
Publication of DK162219C publication Critical patent/DK162219C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK621689A 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner DK162219C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8301366 1983-01-28
FR8301366A FR2540115B1 (fr) 1983-01-28 1983-01-28 Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR8318433A FR2555178B1 (fr) 1983-11-18 1983-11-18 Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant
FR8318433 1983-11-18

Publications (4)

Publication Number Publication Date
DK621689D0 DK621689D0 (da) 1989-12-08
DK621689A DK621689A (da) 1989-12-08
DK162219B DK162219B (da) 1991-09-30
DK162219C true DK162219C (da) 1992-03-02

Family

ID=26223263

Family Applications (3)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem
DK621689A DK162219C (da) 1983-01-28 1989-12-08 3-chlor-4-cyanopyridaziner til syntese af hidtil ukendte 4-cyanopyridaziner
DK621589A DK162218C (da) 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK025984A DK159969C (da) 1983-01-28 1984-01-20 Pyridazinderivater, der har psykotropisk virkning, og laegemidler indeholdende dem

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK621589A DK162218C (da) 1983-01-28 1989-12-08 3-oxo-4-carboxamidopyridaziner til syntese af hidtil ukendte 4-cyano-pyridaziner

Country Status (25)

Country Link
US (2) US4565814A (da)
EP (1) EP0116494B1 (da)
KR (1) KR910000639B1 (da)
AU (1) AU566352B2 (da)
CA (1) CA1218655A (da)
CS (1) CS274405B2 (da)
DD (1) DD215542A5 (da)
DE (1) DE3469026D1 (da)
DK (3) DK159969C (da)
ES (1) ES529108A0 (da)
FI (1) FI77453C (da)
GR (1) GR81682B (da)
HU (1) HU192975B (da)
IE (1) IE56750B1 (da)
IL (1) IL70755A (da)
MA (1) MA20019A1 (da)
NO (1) NO840329L (da)
NZ (1) NZ206957A (da)
OA (1) OA07645A (da)
PH (1) PH21476A (da)
PL (1) PL143994B1 (da)
PT (1) PT77994B (da)
SG (1) SG9389G (da)
SU (1) SU1274623A3 (da)
YU (1) YU14184A (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3672536D1 (de) * 1985-06-14 1990-08-16 Lilly Co Eli Fungizide pyridazine.
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
NZ509748A (en) * 1998-08-20 2003-01-31 Toyama Chemical Co Ltd Nitrogenous heterocyclic carboxamide derivatives or salts useful as antiviral agents
EP1144388B1 (en) 1999-01-22 2010-01-13 Elan Pharmaceuticals, Inc. Acyl derivatives which treat vla-4 related disorders
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
CN1984904A (zh) * 2004-05-08 2007-06-20 神经能质公司 3-芳基-5,6-二取代哒嗪
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
JP5081828B2 (ja) 2005-09-29 2012-11-28 エラン ファーマシューティカルズ,インコーポレイテッド Vla−4によって媒介される白血球粘着を阻害するカルバメート化合物
NZ567270A (en) 2005-09-29 2011-06-30 Elan Pharm Inc Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4
KR20080100271A (ko) 2006-02-27 2008-11-14 엘란 파마슈티칼스, 인크. Vla-4에 의해 매개되는 백혈구 부착을 억제하는 피리미디닐 술폰아미드 화합물
JP2012525336A (ja) 2009-04-27 2012-10-22 エラン ファーマシューティカルズ,インコーポレイテッド α−4インテグリンのピリジノンアンタゴニスト
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant

Also Published As

Publication number Publication date
NZ206957A (en) 1987-06-30
DK162218C (da) 1992-03-02
OA07645A (fr) 1985-05-23
NO840329L (no) 1984-07-30
SG9389G (en) 1989-07-07
AU2372884A (en) 1984-08-02
HU192975B (en) 1987-08-28
KR910000639B1 (ko) 1991-01-31
YU14184A (en) 1986-10-31
DK621689D0 (da) 1989-12-08
DK621589D0 (da) 1989-12-08
IL70755A0 (en) 1984-04-30
GR81682B (da) 1984-12-12
US4565814A (en) 1986-01-21
FI77453B (fi) 1988-11-30
DK162218B (da) 1991-09-30
SU1274623A3 (ru) 1986-11-30
DK25984A (da) 1984-07-29
PL143994B1 (en) 1988-04-30
IL70755A (en) 1987-03-31
CA1218655A (en) 1987-03-03
DK621589A (da) 1989-12-08
PT77994A (fr) 1984-02-01
CS274405B2 (en) 1991-04-11
DK159969C (da) 1991-05-27
DK159969B (da) 1991-01-07
DE3469026D1 (en) 1988-03-03
FI840349A (fi) 1984-07-29
FI840349A0 (fi) 1984-01-27
PT77994B (fr) 1986-04-10
US4631280A (en) 1986-12-23
PH21476A (en) 1987-10-28
EP0116494B1 (fr) 1988-01-27
FI77453C (fi) 1989-03-10
IE840148L (en) 1984-07-28
PL245932A1 (en) 1985-05-21
MA20019A1 (fr) 1984-10-01
CS61484A2 (en) 1990-09-12
IE56750B1 (en) 1991-12-04
ES8500253A1 (es) 1984-10-01
DK621689A (da) 1989-12-08
ES529108A0 (es) 1984-10-01
DK162219B (da) 1991-09-30
DD215542A5 (de) 1984-11-14
EP0116494A1 (fr) 1984-08-22
DK25984D0 (da) 1984-01-20
AU566352B2 (en) 1987-10-15
KR840007587A (ko) 1984-12-08

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