PL2717898T3 - Związki o działaniu prokoagulacyjnym i sposoby ich stosowania - Google Patents

Związki o działaniu prokoagulacyjnym i sposoby ich stosowania

Info

Publication number
PL2717898T3
PL2717898T3 PL12797036T PL12797036T PL2717898T3 PL 2717898 T3 PL2717898 T3 PL 2717898T3 PL 12797036 T PL12797036 T PL 12797036T PL 12797036 T PL12797036 T PL 12797036T PL 2717898 T3 PL2717898 T3 PL 2717898T3
Authority
PL
Poland
Prior art keywords
pro
methods
coagulant compounds
coagulant
compounds
Prior art date
Application number
PL12797036T
Other languages
English (en)
Inventor
Karina THORN
Garabet G. TOBY
Adam R. Mezo
Original Assignee
Bioverativ Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Therapeutics Inc. filed Critical Bioverativ Therapeutics Inc.
Publication of PL2717898T3 publication Critical patent/PL2717898T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
PL12797036T 2011-06-10 2012-06-09 Związki o działaniu prokoagulacyjnym i sposoby ich stosowania PL2717898T3 (pl)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161495818P 2011-06-10 2011-06-10
US201161496543P 2011-06-13 2011-06-13
US201161496540P 2011-06-13 2011-06-13
US201161496542P 2011-06-13 2011-06-13
US201161496541P 2011-06-13 2011-06-13
US201261600237P 2012-02-17 2012-02-17
US201261605540P 2012-03-01 2012-03-01
EP12797036.6A EP2717898B1 (en) 2011-06-10 2012-06-09 Pro-coagulant compounds and methods of use thereof
PCT/US2012/041777 WO2012170969A2 (en) 2011-06-10 2012-06-09 Pro-coagulant compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
PL2717898T3 true PL2717898T3 (pl) 2019-06-28

Family

ID=47296790

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12797036T PL2717898T3 (pl) 2011-06-10 2012-06-09 Związki o działaniu prokoagulacyjnym i sposoby ich stosowania

Country Status (14)

Country Link
US (1) US9486507B2 (pl)
EP (2) EP3527218A1 (pl)
AU (1) AU2012267484B2 (pl)
CA (1) CA2838833A1 (pl)
CY (1) CY1121509T1 (pl)
DK (1) DK2717898T3 (pl)
ES (1) ES2724778T3 (pl)
HR (1) HRP20190494T1 (pl)
HU (1) HUE043894T2 (pl)
LT (1) LT2717898T (pl)
PL (1) PL2717898T3 (pl)
PT (1) PT2717898T (pl)
SI (1) SI2717898T1 (pl)
WO (1) WO2012170969A2 (pl)

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US10317376B2 (en) 2012-04-11 2019-06-11 Bioverativ Therapeutics Inc. Methods of detecting glycosaminoglycans
CA2875247A1 (en) 2012-06-08 2013-12-12 Biogen Idec Ma Inc. Chimeric clotting factors
AU2013270682A1 (en) 2012-06-08 2014-12-11 Biogen Ma Inc. Procoagulant compounds
US10364288B2 (en) 2013-05-24 2019-07-30 Biogen Ma Inc. Anti-GPIIB/IIIA antibodies or uses thereof
TW201536811A (zh) * 2013-05-31 2015-10-01 Biogen Idec Inc 嵌合ｆｖｉｉ－ｘｔｅｎ分子及其用途
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EP3033097B1 (en) 2013-08-14 2021-03-10 Bioverativ Therapeutics Inc. Factor viii-xten fusions and uses thereof
EP3065769A4 (en) * 2013-11-08 2017-05-31 Biogen MA Inc. Procoagulant fusion compound
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WO2016118577A1 (en) * 2015-01-22 2016-07-28 Medimmune, Llc Thymosin-beta-four fusion proteins
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IL319047A (en) * 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
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US10557160B2 (en) 2015-12-15 2020-02-11 Board Of Regents, The University Of Texas System Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same
JP6708751B2 (ja) 2016-04-06 2020-06-10 アルテオジェン・インコーポレイテッド 変形抗体を含む抗体−薬物接合体
WO2017176007A1 (ko) * 2016-04-06 2017-10-12 (주)알테오젠 변형항체를 포함하는 항체-약물 접합체
CA3030163A1 (en) * 2016-07-11 2018-01-18 Board Of Regents, The University Of Texas System Recombinant polypeptides comprising selenocysteine and method for producing the same
CN106317226B (zh) 2016-08-19 2017-09-05 安源医药科技（上海）有限公司 用于构建融合蛋白的连接肽
CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
EP3506945A4 (en) 2016-08-30 2020-07-15 Board of Regents, The University of Texas System PRODUCTION OF SELENO-BIOLOGICALS IN GENETICALLY RECODED ORGANISMS
WO2018102317A1 (en) * 2016-11-29 2018-06-07 The Regents Of The University Of California Modulation of p53 for the treatment of cancer
WO2018102743A1 (en) 2016-12-02 2018-06-07 Bioverativ Therapeutics Inc. Methods of treating hemophilic arthropathy using chimeric clotting factors
US11519917B2 (en) 2017-04-13 2022-12-06 The Regents Of The University Of Michigan Assay for quantifying polyphosphates
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EP3870215A1 (en) * 2018-10-26 2021-09-01 Vrije Universiteit Brussel New tools for improving gene therapy and use thereof
CN109507966A (zh) * 2018-11-20 2019-03-22 东华大学 一种面向纬编面料生产的智能管控系统
CN113101413B (zh) * 2020-01-13 2022-04-08 中国科学院苏州纳米技术与纳米仿生研究所 有序水凝胶纤维支架、其制备方法及应用

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EP2717898A4 (en) 2014-11-26
CA2838833A1 (en) 2012-12-13
NZ619079A (en) 2016-11-25
DK2717898T3 (en) 2019-03-25
LT2717898T (lt) 2019-03-25
EP2717898B1 (en) 2018-12-19
HUE043894T2 (hu) 2019-09-30
CY1121509T1 (el) 2020-05-29
ES2724778T3 (es) 2019-09-16
WO2012170969A2 (en) 2012-12-13
PT2717898T (pt) 2019-05-20
EP3527218A1 (en) 2019-08-21
WO2012170969A3 (en) 2013-08-15
US9486507B2 (en) 2016-11-08
HRP20190494T1 (hr) 2019-07-12
SI2717898T1 (sl) 2019-07-31

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