LT2717898T - Pro-koagulianto junginiai ir jų gavimo būdai - Google Patents

Pro-koagulianto junginiai ir jų gavimo būdai

Info

Publication number
LT2717898T
LT2717898T LTEP12797036.6T LT12797036T LT2717898T LT 2717898 T LT2717898 T LT 2717898T LT 12797036 T LT12797036 T LT 12797036T LT 2717898 T LT2717898 T LT 2717898T
Authority
LT
Lithuania
Prior art keywords
pro
methods
coagulant compounds
coagulant
compounds
Prior art date
Application number
LTEP12797036.6T
Other languages
English (en)
Inventor
Karina THORN
Garabet G. TOBY
Adam R. Mezo
Original Assignee
Bioverativ Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioverativ Therapeutics Inc. filed Critical Bioverativ Therapeutics Inc.
Publication of LT2717898T publication Critical patent/LT2717898T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
LTEP12797036.6T 2011-06-10 2012-06-09 Pro-koagulianto junginiai ir jų gavimo būdai LT2717898T (lt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201161495818P 2011-06-10 2011-06-10
US201161496541P 2011-06-13 2011-06-13
US201161496540P 2011-06-13 2011-06-13
US201161496543P 2011-06-13 2011-06-13
US201161496542P 2011-06-13 2011-06-13
US201261600237P 2012-02-17 2012-02-17
US201261605540P 2012-03-01 2012-03-01
PCT/US2012/041777 WO2012170969A2 (en) 2011-06-10 2012-06-09 Pro-coagulant compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
LT2717898T true LT2717898T (lt) 2019-03-25

Family

ID=47296790

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP12797036.6T LT2717898T (lt) 2011-06-10 2012-06-09 Pro-koagulianto junginiai ir jų gavimo būdai

Country Status (14)

Country Link
US (1) US9486507B2 (lt)
EP (2) EP2717898B1 (lt)
AU (1) AU2012267484B2 (lt)
CA (1) CA2838833A1 (lt)
CY (1) CY1121509T1 (lt)
DK (1) DK2717898T3 (lt)
ES (1) ES2724778T3 (lt)
HR (1) HRP20190494T1 (lt)
HU (1) HUE043894T2 (lt)
LT (1) LT2717898T (lt)
PL (1) PL2717898T3 (lt)
PT (1) PT2717898T (lt)
SI (1) SI2717898T1 (lt)
WO (1) WO2012170969A2 (lt)

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CN106279437B (zh) * 2016-08-19 2017-10-31 安源医药科技（上海）有限公司 高糖基化人凝血因子viii融合蛋白及其制备方法与用途
CN106317226B (zh) 2016-08-19 2017-09-05 安源医药科技（上海）有限公司 用于构建融合蛋白的连接肽
EP3506945A4 (en) 2016-08-30 2020-07-15 Board of Regents, The University of Texas System PRODUCTION OF SELENO-BIOLOGICALS IN GENETICALLY RECODED ORGANISMS
WO2018102317A1 (en) * 2016-11-29 2018-06-07 The Regents Of The University Of California Modulation of p53 for the treatment of cancer
WO2018191582A1 (en) * 2017-04-13 2018-10-18 The Board Of Trustees Of The University Of Illinois Assay for quantifying polyphosphates
EP3870215A1 (en) * 2018-10-26 2021-09-01 Vrije Universiteit Brussel New tools for improving gene therapy and use thereof
CN109507966A (zh) * 2018-11-20 2019-03-22 东华大学 一种面向纬编面料生产的智能管控系统
CN113101413B (zh) * 2020-01-13 2022-04-08 中国科学院苏州纳米技术与纳米仿生研究所 有序水凝胶纤维支架、其制备方法及应用

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US9486507B2 (en) 2016-11-08
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SI2717898T1 (sl) 2019-07-31
CY1121509T1 (el) 2020-05-29
CA2838833A1 (en) 2012-12-13
AU2012267484A1 (en) 2014-01-16
US20140303084A1 (en) 2014-10-09
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EP2717898A4 (en) 2014-11-26
EP2717898A2 (en) 2014-04-16
PT2717898T (pt) 2019-05-20
AU2012267484B2 (en) 2017-03-23
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HUE043894T2 (hu) 2019-09-30
EP3527218A1 (en) 2019-08-21

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