ATE30033T1 - Verfahren zur herstellung von retro-inverso polypeptiden in fester phase. - Google Patents
Verfahren zur herstellung von retro-inverso polypeptiden in fester phase.Info
- Publication number
- ATE30033T1 ATE30033T1 AT83200889T AT83200889T ATE30033T1 AT E30033 T1 ATE30033 T1 AT E30033T1 AT 83200889 T AT83200889 T AT 83200889T AT 83200889 T AT83200889 T AT 83200889T AT E30033 T1 ATE30033 T1 AT E30033T1
- Authority
- AT
- Austria
- Prior art keywords
- retro
- inverso
- production
- bis
- solid phase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22046/82A IT1190891B (it) | 1982-06-24 | 1982-06-24 | Metodo per la sintesi in fase solida di polipeptidi retroinvertiti |
EP83200889A EP0097994B1 (de) | 1982-06-24 | 1983-06-17 | Verfahren zur Herstellung von retro-inverso Polypeptiden in fester Phase |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE30033T1 true ATE30033T1 (de) | 1987-10-15 |
Family
ID=11190672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT83200889T ATE30033T1 (de) | 1982-06-24 | 1983-06-17 | Verfahren zur herstellung von retro-inverso polypeptiden in fester phase. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0097994B1 (de) |
AT (1) | ATE30033T1 (de) |
DE (1) | DE3373908D1 (de) |
IT (1) | IT1190891B (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU573735B2 (en) * | 1983-02-07 | 1988-06-23 | Aktiebolaget Hassle | Peptide analogue enzyme inhibitors |
IT1164225B (it) * | 1983-05-13 | 1987-04-08 | Anic Spa | Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione |
IT1164240B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica |
IT1164239B (it) * | 1983-05-25 | 1987-04-08 | Anic Spa | Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica |
US4668476A (en) * | 1984-03-23 | 1987-05-26 | Applied Biosystems, Inc. | Automated polypeptide synthesis apparatus |
IT1178786B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Analoghi retro-inverso parzialmente modificati della neurotensina |
IT1178789B (it) * | 1984-12-21 | 1987-09-16 | Assorenti | Peptidi retro-invertiti analoghi del potenziatore della bradichinina bpp 5a |
IT1184317B (it) * | 1985-02-05 | 1987-10-28 | Eniricerche Spa | Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a |
IT1190389B (it) * | 1985-09-19 | 1988-02-16 | Eniricerche Spa | Esapeptidi ad attivita' ipotensiva |
IT1188206B (it) * | 1985-11-28 | 1988-01-07 | Eniricerche Spa | Procedimento per la sintesi in fase solida di peptidi in cui almeno un legame ammidico e' retroinvertito |
GB2187461A (en) * | 1986-02-03 | 1987-09-09 | Medical Res Council | Monitoring method for the synthesis of a linear of amino acid residues |
ES2052517T3 (es) * | 1986-07-16 | 1994-07-16 | Eniricerche Spa | Analogos de tuftsina parcialmente retroinversos, metodo de preparacion de los mismos y composiciones farmaceuticas que los contienen. |
IT1196500B (it) * | 1986-07-16 | 1988-11-16 | Eniricerche Spa | Derivati dell'acido malonico e metodi per la loro sintesi |
HUT71860A (en) * | 1992-08-27 | 1996-02-28 | Deakin Res Ltd | Retro-, inverso-, and retro-inverso synthetic peptide analogues |
FR2717081B1 (fr) * | 1994-03-14 | 1996-06-21 | Centre Nat Rech Scient | Rétropeptides, anticorps dirigés contre ces derniers, et leurs utilisations pour la vaccination et le diagnostic in vitro. |
US6916904B2 (en) | 2002-04-24 | 2005-07-12 | Zolaris Biosciences, Llc | Inhibition of immune complex formation |
EP1730170B1 (de) | 2004-03-10 | 2020-02-19 | Trinity Therapeutics, Inc. | Verfahren zur inhibierung der immunkomplexbildung in einem probanden |
WO2008124768A1 (en) | 2007-04-09 | 2008-10-16 | The General Hospital Corporation | Hemojuvelin fusion proteins and uses thereof |
AR071478A1 (es) | 2008-04-17 | 2010-06-23 | Baxter Healthcare Sa | Peptidos de bajo peso molecular con actividad procoagulante para el tratamiento de pacientes con deficiencia de factor v (fv), fvii, fviii, fx y/o fxi |
MY160699A (en) | 2008-07-18 | 2017-03-15 | Trinity Therapeutics Inc | Methods for treating immune-mediated dengue fever infections and antibody-dependent enhancement of dengue fever infections, including dengue hemorrhagic fever and dengue shock syndrome |
EP3406267A1 (de) | 2011-03-25 | 2018-11-28 | Children's Medical Center Corporation | Lin28-vermittelte steuerung der let-7-biogenese |
EP3527218A1 (de) | 2011-06-10 | 2019-08-21 | Bioverativ Therapeutics Inc. | Gerinnungsfördernde verbindungen und verfahren zur verwendung davon |
MX365403B (es) | 2012-01-09 | 2019-05-31 | Serpin Pharma Llc | Peptidos y metodos para usarlos. |
CA2877886A1 (en) | 2012-06-25 | 2014-01-03 | The Brigham And Women's Hospital, Inc. | Targeted therapeutics comprising heparin binding protein |
BR112015022181A8 (pt) | 2013-03-12 | 2018-01-23 | Massachusetts Eye & Ear Infirmary | proteínas da substância de inibição mulleriana (mis) e usos das mesmas para o tratamento de doenças |
WO2015070014A1 (en) | 2013-11-08 | 2015-05-14 | Biogen Idec Ma Inc. | Procoagulant fusion compound |
WO2016044707A1 (en) | 2014-09-18 | 2016-03-24 | Cedars-Sinai Medical Center | Compositions and methods for treating fibrosis |
WO2016172479A1 (en) | 2015-04-22 | 2016-10-27 | Cedars-Sinai Medical Center | Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes |
US11020462B2 (en) | 2015-08-28 | 2021-06-01 | Serpin Pharma | Methods for treatment of diseases |
WO2017075465A1 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3 |
EP3368689B1 (de) | 2015-10-28 | 2020-06-17 | The Broad Institute, Inc. | Zusammensetzungen zur modulierung von immunantworten unter verwendung von immunzellgensignaturen |
WO2017075451A1 (en) | 2015-10-28 | 2017-05-04 | The Broad Institute Inc. | Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1 |
US20190262399A1 (en) | 2016-09-07 | 2019-08-29 | The Broad Institute, Inc. | Compositions and methods for evaluating and modulating immune responses |
AU2019339264A1 (en) | 2018-09-10 | 2021-03-11 | Board Of Regents, The University Of Texas System | Dry powder formulation of caveolin-1 peptides and methods of use thereof |
US11905336B2 (en) | 2018-09-10 | 2024-02-20 | Lung Therapeutics, Inc. | Modified peptide fragments of CAV-1 protein and the use thereof in the treatment of fibrosis |
US20230374153A1 (en) | 2022-04-13 | 2023-11-23 | Paradigm Immunoterapeutics, Inc. | METHODS OF PREVENTING OR TREATING INFECTION BY RESPIRATORY VIRUSES INCLUDING SARS-CoV-2 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3862114A (en) * | 1971-11-22 | 1975-01-21 | Ici Australia Ltd | Analogs of substance p |
-
1982
- 1982-06-24 IT IT22046/82A patent/IT1190891B/it active
-
1983
- 1983-06-17 AT AT83200889T patent/ATE30033T1/de not_active IP Right Cessation
- 1983-06-17 EP EP83200889A patent/EP0097994B1/de not_active Expired
- 1983-06-17 DE DE8383200889T patent/DE3373908D1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE3373908D1 (en) | 1987-11-05 |
EP0097994A3 (en) | 1985-11-27 |
EP0097994B1 (de) | 1987-09-30 |
EP0097994A2 (de) | 1984-01-11 |
IT1190891B (it) | 1988-02-24 |
IT8222046A0 (it) | 1982-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEIH | Change in the person of patent owner | ||
REN | Ceased due to non-payment of the annual fee |