DE3582786D1 - Teilweise modifizierte analogen von retroinverso neurotensinen. - Google Patents

Teilweise modifizierte analogen von retroinverso neurotensinen.

Info

Publication number
DE3582786D1
DE3582786D1 DE8585115888T DE3582786T DE3582786D1 DE 3582786 D1 DE3582786 D1 DE 3582786D1 DE 8585115888 T DE8585115888 T DE 8585115888T DE 3582786 T DE3582786 T DE 3582786T DE 3582786 D1 DE3582786 D1 DE 3582786D1
Authority
DE
Germany
Prior art keywords
sub
neurotensines
retroinverso
modified analogs
partly modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585115888T
Other languages
English (en)
Inventor
Fabio Bonelli
Antonello Pessi
Antonio Silvio Verdini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sclavo SpA
Eni Tecnologie SpA
Original Assignee
Sclavo SpA
Eniricerche SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sclavo SpA, Eniricerche SpA filed Critical Sclavo SpA
Application granted granted Critical
Publication of DE3582786D1 publication Critical patent/DE3582786D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE8585115888T 1984-12-21 1985-12-12 Teilweise modifizierte analogen von retroinverso neurotensinen. Expired - Lifetime DE3582786D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT24197/84A IT1178786B (it) 1984-12-21 1984-12-21 Analoghi retro-inverso parzialmente modificati della neurotensina

Publications (1)

Publication Number Publication Date
DE3582786D1 true DE3582786D1 (de) 1991-06-13

Family

ID=11212494

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585115888T Expired - Lifetime DE3582786D1 (de) 1984-12-21 1985-12-12 Teilweise modifizierte analogen von retroinverso neurotensinen.

Country Status (6)

Country Link
US (1) US4716149A (de)
EP (1) EP0185320B1 (de)
JP (1) JPS61155396A (de)
AT (1) ATE63317T1 (de)
DE (1) DE3582786D1 (de)
IT (1) IT1178786B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
EP0253190B1 (de) * 1986-07-16 1992-12-30 ENIRICERCHE S.p.A. Teilweise retro-invertierte Analoge des Tuftsin, Methode zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
AU3534989A (en) * 1988-04-08 1989-11-03 Scripps Clinic And Research Foundation Polypeptides stabilized by covalent hydrogen bond replacements
US5807979A (en) * 1988-04-08 1998-09-15 The Scripps Research Institute Synthetic, three-dimensionally stabilized polypeptide mimics of HIV
US5374621A (en) * 1991-09-13 1994-12-20 Regents Of The University Of California Neurotensin method for inhibiting vascular leakage
AU2019217207A1 (en) 2018-02-12 2020-08-27 Diabetes-Free, Inc. Improved antagonistic anti-human CD40 monoclonal antibodies
WO2020102454A1 (en) 2018-11-13 2020-05-22 Regents Of The University Of Minnesota Cd40 targeted peptides and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3929756A (en) * 1973-11-21 1975-12-30 Univ Brandeis Synthetically produced tridecapeptide having the same activity as the hypothalamic substance, neurotensin
US4110321A (en) * 1976-07-12 1978-08-29 Folkers Karl Synthetic tridecapeptide [Gln4 ]-neurotensin having hormonal activity
US4331661A (en) * 1980-10-03 1982-05-25 The Salk Institute For Biological Studies Bombesin analogs
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
IT1190891B (it) * 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
US4439359A (en) * 1982-07-02 1984-03-27 Merck & Co., Inc. Cyclic octapeptide analogs of neurotensin
US4613586A (en) * 1984-04-19 1986-09-23 Board Of Trustees Of The Leland Stanford Junior University Gastrin releasing peptide-like peptides

Also Published As

Publication number Publication date
JPS61155396A (ja) 1986-07-15
ATE63317T1 (de) 1991-05-15
EP0185320B1 (de) 1991-05-08
EP0185320A3 (en) 1988-03-16
IT1178786B (it) 1987-09-16
IT8424197A0 (it) 1984-12-21
EP0185320A2 (de) 1986-06-25
US4716149A (en) 1987-12-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee