BR9809910A - Peptìdeos lh-rh análogos, seus usos e composições farmacêuticas contendo-os - Google Patents

Peptìdeos lh-rh análogos, seus usos e composições farmacêuticas contendo-os

Info

Publication number
BR9809910A
BR9809910A BR9809910-8A BR9809910A BR9809910A BR 9809910 A BR9809910 A BR 9809910A BR 9809910 A BR9809910 A BR 9809910A BR 9809910 A BR9809910 A BR 9809910A
Authority
BR
Brazil
Prior art keywords
peptides
analogous
pharmaceutical compositions
compositions containing
haa
Prior art date
Application number
BR9809910-8A
Other languages
English (en)
Inventor
Remi Delansorne
Jacques Paris
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Publication of BR9809910A publication Critical patent/BR9809910A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção para <B>"PEPTìDEOS LH-RH ANáLOGOS , SEUS USOS E COMPOSIçõES FARMACêUTICAS CONTENDO-OS"<D>. A invenção refere-se aos peptídeos LH-RH análogos com excelente afinidade aos receptores LH-RH, de fórmula (I): A1-A2-A3-A4-A5-A6-HAA-A7-Pro-Z em que Z, A1 a A7 são especificados na descrição e HAA é um amino ácido hidrofóbico não aromático possuindo de 7 a 20 átomos e carbono. A invenção refere-se também aos usos dos ditos peptídeos análogos e às composições farmacêuticas contendo-os.
BR9809910-8A 1997-06-02 1998-05-06 Peptìdeos lh-rh análogos, seus usos e composições farmacêuticas contendo-os BR9809910A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97401212A EP0882736A1 (en) 1997-06-02 1997-06-02 LH-RH peptide analogues, their uses and pharmaceutical compositions containing them
PCT/EP1998/002802 WO1998055505A1 (en) 1997-06-02 1998-05-06 Lh-rh peptide analogues, their uses and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
BR9809910A true BR9809910A (pt) 2000-08-01

Family

ID=8229769

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809910-8A BR9809910A (pt) 1997-06-02 1998-05-06 Peptìdeos lh-rh análogos, seus usos e composições farmacêuticas contendo-os

Country Status (38)

Country Link
US (1) US6586402B1 (pt)
EP (2) EP0882736A1 (pt)
JP (1) JP4346115B2 (pt)
KR (1) KR100582510B1 (pt)
CN (1) CN1134450C (pt)
AP (1) AP1195A (pt)
AR (1) AR011734A1 (pt)
AT (1) ATE204297T1 (pt)
AU (1) AU746132B2 (pt)
BR (1) BR9809910A (pt)
CA (1) CA2292846C (pt)
CO (1) CO4790174A1 (pt)
CZ (1) CZ299308B6 (pt)
DE (1) DE69801369T2 (pt)
DK (1) DK0984982T3 (pt)
DZ (1) DZ2509A1 (pt)
EE (1) EE03879B1 (pt)
ES (1) ES2166166T3 (pt)
HK (1) HK1029124A1 (pt)
HU (1) HUP0003592A3 (pt)
ID (1) ID24520A (pt)
IL (1) IL133210A0 (pt)
JO (1) JO2034B1 (pt)
MA (1) MA26502A1 (pt)
MY (1) MY122262A (pt)
NO (1) NO321786B1 (pt)
NZ (1) NZ501463A (pt)
OA (1) OA11305A (pt)
PE (1) PE84999A1 (pt)
PL (1) PL195474B1 (pt)
PT (1) PT984982E (pt)
RU (1) RU2212247C2 (pt)
SI (1) SI0984982T1 (pt)
TN (1) TNSN98075A1 (pt)
TR (1) TR199902997T2 (pt)
TW (1) TW479062B (pt)
WO (1) WO1998055505A1 (pt)
ZA (1) ZA983992B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882736A1 (en) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. LH-RH peptide analogues, their uses and pharmaceutical compositions containing them
US20020071829A1 (en) * 1999-04-15 2002-06-13 Richard Boyd Normalization of defective T cell responsiveness through manipulation of thymic regeneration
WO2002030351A2 (en) * 2000-10-13 2002-04-18 Monash University Improvement of graft acceptance through manipulation of thymic regeneration
GB0307777D0 (en) 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
DE102004033902A1 (de) * 2004-07-14 2006-02-16 Zentaris Gmbh Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's)
AU2006326404B2 (en) 2005-12-14 2011-11-03 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
CN102675418B (zh) * 2011-03-15 2016-04-20 中国人民解放军军事医学科学院毒物药物研究所 Lhrh拮抗剂衍生物、其制备方法及用途
EP3663758A1 (en) * 2012-03-18 2020-06-10 Shiseido Company, Ltd. Apparatus, system and method for analyzing disease sample
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9393264B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
CN104418936B (zh) * 2013-08-20 2018-06-05 中国人民解放军军事医学科学院毒物药物研究所 Lhrh拮抗剂衍生物及其药物用途
CN114014913B (zh) * 2022-01-10 2022-03-29 浙江湃肽生物有限公司南京分公司 醋酸曲普瑞林的纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO139560C (no) * 1972-04-29 1979-04-04 Takeda Chemical Industries Ltd Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater
DE2424287A1 (de) * 1974-05-18 1975-12-04 Hoechst Ag Peptide mit lh-rh/fsh-rh-wirkung und verfahren zu ihrer herstellung
NL7505590A (nl) * 1974-05-18 1975-11-20 Hoechst Ag Werkwijze voor het bereiden van peptiden met lh-rh/fsh-rh-werking.
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
US5003011A (en) * 1985-04-09 1991-03-26 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists
EP0328090A3 (en) * 1988-02-10 1990-08-16 Abbott Laboratories Lhrh analogs
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
EP0842946A1 (en) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them
EP0882736A1 (en) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. LH-RH peptide analogues, their uses and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JO2034B1 (en) 1999-05-15
KR20010013286A (ko) 2001-02-26
SI0984982T1 (en) 2002-02-28
PE84999A1 (es) 1999-09-15
CA2292846A1 (en) 1998-12-10
TW479062B (en) 2002-03-11
MY122262A (en) 2006-04-29
NO995891D0 (no) 1999-12-01
JP4346115B2 (ja) 2009-10-21
EP0984982A1 (en) 2000-03-15
AP9901702A0 (en) 1999-12-31
HUP0003592A2 (hu) 2001-02-28
ZA983992B (en) 1998-11-20
ES2166166T3 (es) 2002-04-01
JP2002502396A (ja) 2002-01-22
AP1195A (en) 2003-08-18
AU746132B2 (en) 2002-04-18
PL195474B1 (pl) 2007-09-28
EE03879B1 (et) 2002-10-15
KR100582510B1 (ko) 2006-05-23
AU7654198A (en) 1998-12-21
IL133210A0 (en) 2001-03-19
AR011734A1 (es) 2000-08-30
CA2292846C (en) 2009-12-08
EP0984982B1 (en) 2001-08-16
DE69801369T2 (de) 2002-05-16
MA26502A1 (fr) 2004-12-20
RU2212247C2 (ru) 2003-09-20
US6586402B1 (en) 2003-07-01
CN1134450C (zh) 2004-01-14
CZ432999A3 (cs) 2000-06-14
NO995891L (no) 2000-02-01
HUP0003592A3 (en) 2001-05-28
ATE204297T1 (de) 2001-09-15
EP0882736A1 (en) 1998-12-09
HK1029124A1 (en) 2001-03-23
OA11305A (en) 2003-08-25
CO4790174A1 (es) 1999-05-31
DK0984982T3 (da) 2001-11-12
WO1998055505A1 (en) 1998-12-10
PT984982E (pt) 2002-02-28
TNSN98075A1 (fr) 2005-03-15
NO321786B1 (no) 2006-07-03
EE9900546A (et) 2000-06-15
NZ501463A (en) 2001-07-27
DE69801369D1 (de) 2001-09-20
PL337235A1 (en) 2000-08-14
TR199902997T2 (xx) 2000-03-21
CN1263535A (zh) 2000-08-16
ID24520A (id) 2000-07-20
DZ2509A1 (fr) 2003-01-25
CZ299308B6 (cs) 2008-06-11

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 37 DA LPI 9279/96, OPINO PELO INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE: - NAO APRESENTA SUFICIENCIA DESCRITIVA (ARTIGO 24 DA LPI); - AS REIVINDICACOES ESTAO INDEFINIDAS E/OU NAO ESTAO FUNDAMENTADAS NO RELATORIO DESCRITIVO (ARTIGO 25 DA LPI).

B12B Appeal against refusal [chapter 12.2 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time