DE69801369D1 - Peptidanaloge des lh-rh, ihre verwendungen und die sie enthaltenden pharmazeutischen zusammensetzungen - Google Patents

Peptidanaloge des lh-rh, ihre verwendungen und die sie enthaltenden pharmazeutischen zusammensetzungen

Info

Publication number
DE69801369D1
DE69801369D1 DE69801369T DE69801369T DE69801369D1 DE 69801369 D1 DE69801369 D1 DE 69801369D1 DE 69801369 T DE69801369 T DE 69801369T DE 69801369 T DE69801369 T DE 69801369T DE 69801369 D1 DE69801369 D1 DE 69801369D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
compositions containing
peptide analogs
analogs
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69801369T
Other languages
English (en)
Other versions
DE69801369T2 (de
Inventor
Remi Delansorne
Jacques Paris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Theramex SAM
Original Assignee
Laboratoire Theramex SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex SAM filed Critical Laboratoire Theramex SAM
Publication of DE69801369D1 publication Critical patent/DE69801369D1/de
Application granted granted Critical
Publication of DE69801369T2 publication Critical patent/DE69801369T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
DE69801369T 1997-06-02 1998-05-06 Peptidanaloge des lh-rh, ihre verwendungen und die sie enthaltenden pharmazeutischen zusammensetzungen Expired - Lifetime DE69801369T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97401212A EP0882736A1 (de) 1997-06-02 1997-06-02 Peptidanaloge des LH-RH, ihre Verwendungen und die sie enthaltenden pharmazeutischen Zusammensetzungen
PCT/EP1998/002802 WO1998055505A1 (en) 1997-06-02 1998-05-06 Lh-rh peptide analogues, their uses and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69801369D1 true DE69801369D1 (de) 2001-09-20
DE69801369T2 DE69801369T2 (de) 2002-05-16

Family

ID=8229769

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69801369T Expired - Lifetime DE69801369T2 (de) 1997-06-02 1998-05-06 Peptidanaloge des lh-rh, ihre verwendungen und die sie enthaltenden pharmazeutischen zusammensetzungen

Country Status (38)

Country Link
US (1) US6586402B1 (de)
EP (2) EP0882736A1 (de)
JP (1) JP4346115B2 (de)
KR (1) KR100582510B1 (de)
CN (1) CN1134450C (de)
AP (1) AP1195A (de)
AR (1) AR011734A1 (de)
AT (1) ATE204297T1 (de)
AU (1) AU746132B2 (de)
BR (1) BR9809910A (de)
CA (1) CA2292846C (de)
CO (1) CO4790174A1 (de)
CZ (1) CZ299308B6 (de)
DE (1) DE69801369T2 (de)
DK (1) DK0984982T3 (de)
DZ (1) DZ2509A1 (de)
EE (1) EE03879B1 (de)
ES (1) ES2166166T3 (de)
HK (1) HK1029124A1 (de)
HU (1) HUP0003592A3 (de)
ID (1) ID24520A (de)
IL (1) IL133210A0 (de)
JO (1) JO2034B1 (de)
MA (1) MA26502A1 (de)
MY (1) MY122262A (de)
NO (1) NO321786B1 (de)
NZ (1) NZ501463A (de)
OA (1) OA11305A (de)
PE (1) PE84999A1 (de)
PL (1) PL195474B1 (de)
PT (1) PT984982E (de)
RU (1) RU2212247C2 (de)
SI (1) SI0984982T1 (de)
TN (1) TNSN98075A1 (de)
TR (1) TR199902997T2 (de)
TW (1) TW479062B (de)
WO (1) WO1998055505A1 (de)
ZA (1) ZA983992B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882736A1 (de) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. Peptidanaloge des LH-RH, ihre Verwendungen und die sie enthaltenden pharmazeutischen Zusammensetzungen
US20020071829A1 (en) * 1999-04-15 2002-06-13 Richard Boyd Normalization of defective T cell responsiveness through manipulation of thymic regeneration
CA2462046A1 (en) * 2000-10-13 2002-04-18 Monash University Improvement of graft acceptance through manipulation of thymic regeneration
GB0307777D0 (en) 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
DE102004033902A1 (de) * 2004-07-14 2006-02-16 Zentaris Gmbh Neue Tetrahydrocarbazolderivate mit verbesserter biologischer Wirkung und verbesserter Löslichkeit als Liganden für G-Protein gekoppelte Rezeptoren (GPCR's)
CN105384807A (zh) * 2005-12-14 2016-03-09 Ambrx公司 含有非天然氨基酸和多肽的组合物、涉及非天然氨基酸和多肽的方法以及非天然氨基酸和多肽的用途
CN102675418B (zh) * 2011-03-15 2016-04-20 中国人民解放军军事医学科学院毒物药物研究所 Lhrh拮抗剂衍生物、其制备方法及用途
CN110133299A (zh) * 2012-03-18 2019-08-16 株式会社资生堂 疾病样品分析装置、分析系统及分析方法
US20140271937A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9339457B2 (en) 2013-03-13 2016-05-17 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9314423B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Hair treatment systems and methods using peptides and other compositions
US9393265B2 (en) 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9241899B2 (en) 2013-03-13 2016-01-26 Transdermal Biotechnology, Inc. Topical systems and methods for treating sexual dysfunction
US9393264B2 (en) * 2013-03-13 2016-07-19 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9295636B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Wound healing using topical systems and methods
US9295637B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Compositions and methods for affecting mood states
US9314422B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
US9314433B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US20140271731A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Cardiovascular disease treatment and prevention
US9320758B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Brain and neural treatments comprising peptides and other compositions
US9387159B2 (en) 2013-03-13 2016-07-12 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9314417B2 (en) 2013-03-13 2016-04-19 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance
US9849160B2 (en) 2013-03-13 2017-12-26 Transdermal Biotechnology, Inc. Methods and systems for treating or preventing cancer
US20140271938A1 (en) 2013-03-13 2014-09-18 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9687520B2 (en) 2013-03-13 2017-06-27 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9295647B2 (en) 2013-03-13 2016-03-29 Transdermal Biotechnology, Inc. Systems and methods for delivery of peptides
US9750787B2 (en) 2013-03-13 2017-09-05 Transdermal Biotechnology, Inc. Memory or learning improvement using peptide and other compositions
US9320706B2 (en) 2013-03-13 2016-04-26 Transdermal Biotechnology, Inc. Immune modulation using peptides and other compositions
US9724419B2 (en) 2013-03-13 2017-08-08 Transdermal Biotechnology, Inc. Peptide systems and methods for metabolic conditions
CN104418936B (zh) * 2013-08-20 2018-06-05 中国人民解放军军事医学科学院毒物药物研究所 Lhrh拮抗剂衍生物及其药物用途
CN114014913B (zh) * 2022-01-10 2022-03-29 浙江湃肽生物有限公司南京分公司 醋酸曲普瑞林的纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO139560C (no) * 1972-04-29 1979-04-04 Takeda Chemical Industries Ltd Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater
NL7505590A (nl) * 1974-05-18 1975-11-20 Hoechst Ag Werkwijze voor het bereiden van peptiden met lh-rh/fsh-rh-werking.
DE2424287A1 (de) * 1974-05-18 1975-12-04 Hoechst Ag Peptide mit lh-rh/fsh-rh-wirkung und verfahren zu ihrer herstellung
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
US5003011A (en) * 1985-04-09 1991-03-26 The Administrators Of The Tulane Educational Fund Therapeutic decapeptides
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
WO1989007450A1 (en) * 1988-02-10 1989-08-24 Abbott Laboratories Lhrh analogs
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
EP0842946A1 (de) * 1996-11-14 1998-05-20 Laboratoire Theramex S.A. LHRH Analoge mit starrer Konformation, deren Verwendungen und pharmazeutische Zusammensetzungen
EP0882736A1 (de) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. Peptidanaloge des LH-RH, ihre Verwendungen und die sie enthaltenden pharmazeutischen Zusammensetzungen

Also Published As

Publication number Publication date
EE9900546A (et) 2000-06-15
MY122262A (en) 2006-04-29
MA26502A1 (fr) 2004-12-20
JP4346115B2 (ja) 2009-10-21
PL337235A1 (en) 2000-08-14
DZ2509A1 (fr) 2003-01-25
JO2034B1 (en) 1999-05-15
HUP0003592A3 (en) 2001-05-28
CN1134450C (zh) 2004-01-14
DK0984982T3 (da) 2001-11-12
US6586402B1 (en) 2003-07-01
TW479062B (en) 2002-03-11
ATE204297T1 (de) 2001-09-15
ZA983992B (en) 1998-11-20
CZ299308B6 (cs) 2008-06-11
ES2166166T3 (es) 2002-04-01
CA2292846A1 (en) 1998-12-10
AP9901702A0 (en) 1999-12-31
NO995891L (no) 2000-02-01
BR9809910A (pt) 2000-08-01
ID24520A (id) 2000-07-20
CO4790174A1 (es) 1999-05-31
AP1195A (en) 2003-08-18
NO995891D0 (no) 1999-12-01
EP0882736A1 (de) 1998-12-09
TNSN98075A1 (fr) 2005-03-15
NO321786B1 (no) 2006-07-03
AU7654198A (en) 1998-12-21
CN1263535A (zh) 2000-08-16
CZ432999A3 (cs) 2000-06-14
OA11305A (en) 2003-08-25
TR199902997T2 (xx) 2000-03-21
NZ501463A (en) 2001-07-27
AU746132B2 (en) 2002-04-18
AR011734A1 (es) 2000-08-30
RU2212247C2 (ru) 2003-09-20
CA2292846C (en) 2009-12-08
EP0984982A1 (de) 2000-03-15
HK1029124A1 (en) 2001-03-23
PE84999A1 (es) 1999-09-15
HUP0003592A2 (hu) 2001-02-28
SI0984982T1 (en) 2002-02-28
PT984982E (pt) 2002-02-28
EP0984982B1 (de) 2001-08-16
DE69801369T2 (de) 2002-05-16
WO1998055505A1 (en) 1998-12-10
KR100582510B1 (ko) 2006-05-23
EE03879B1 (et) 2002-10-15
JP2002502396A (ja) 2002-01-22
KR20010013286A (ko) 2001-02-26
PL195474B1 (pl) 2007-09-28
IL133210A0 (en) 2001-03-19

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Legal Events

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8364 No opposition during term of opposition