IT8125753A0 - Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori - Google Patents

Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori

Info

Publication number
IT8125753A0
IT8125753A0 IT8125753A IT2575381A IT8125753A0 IT 8125753 A0 IT8125753 A0 IT 8125753A0 IT 8125753 A IT8125753 A IT 8125753A IT 2575381 A IT2575381 A IT 2575381A IT 8125753 A0 IT8125753 A0 IT 8125753A0
Authority
IT
Italy
Prior art keywords
hexapeptides
vasodilators
penta
inverted
terminals
Prior art date
Application number
IT8125753A
Other languages
English (en)
Other versions
IT1212508B (it
Inventor
Antonio Silvio Verdini
Giuseppe Claudio Viscomi
Original Assignee
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anic Spa filed Critical Anic Spa
Priority to IT8125753A priority Critical patent/IT1212508B/it
Publication of IT8125753A0 publication Critical patent/IT8125753A0/it
Priority to US06/448,832 priority patent/US4439360A/en
Priority to AT82201612T priority patent/ATE10364T1/de
Priority to DE8282201612T priority patent/DE3261304D1/de
Priority to EP82201612A priority patent/EP0082568B1/en
Priority to CA000418173A priority patent/CA1249698A/en
Priority to JP57224103A priority patent/JPS58116443A/ja
Application granted granted Critical
Publication of IT1212508B publication Critical patent/IT1212508B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8125753A 1981-12-22 1981-12-22 Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori IT1212508B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT8125753A IT1212508B (it) 1981-12-22 1981-12-22 Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
US06/448,832 US4439360A (en) 1981-12-22 1982-12-10 Retro-inverso analogues of C-terminal penta and hexapeptides of Substance P
AT82201612T ATE10364T1 (de) 1981-12-22 1982-12-16 Retro-inverso analoga von c-terminalen pentaund hexapeptiden der verbindung p.
DE8282201612T DE3261304D1 (en) 1981-12-22 1982-12-16 Retro-inverso analogues of c-terminal penta and hexapeptides of substance p.
EP82201612A EP0082568B1 (en) 1981-12-22 1982-12-16 Retro-inverso analogues of c-terminal penta and hexapeptides of substance p.
CA000418173A CA1249698A (en) 1981-12-22 1982-12-21 Retro-inverso analogues of c-terminal penta and hexapeptides of substance p
JP57224103A JPS58116443A (ja) 1981-12-22 1982-12-22 新規ペプチドおよびその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8125753A IT1212508B (it) 1981-12-22 1981-12-22 Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori

Publications (2)

Publication Number Publication Date
IT8125753A0 true IT8125753A0 (it) 1981-12-22
IT1212508B IT1212508B (it) 1989-11-22

Family

ID=11217635

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8125753A IT1212508B (it) 1981-12-22 1981-12-22 Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori

Country Status (7)

Country Link
US (1) US4439360A (it)
EP (1) EP0082568B1 (it)
JP (1) JPS58116443A (it)
AT (1) ATE10364T1 (it)
CA (1) CA1249698A (it)
DE (1) DE3261304D1 (it)
IT (1) IT1212508B (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0316965A3 (en) * 1983-02-07 1989-08-09 Aktiebolaget Hässle Enzyme inhibitors
IT1164225B (it) * 1983-05-13 1987-04-08 Anic Spa Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
IT1164239B (it) * 1983-05-25 1987-04-08 Anic Spa Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
IT1164240B (it) * 1983-05-25 1987-04-08 Anic Spa Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica
IT1206339B (it) * 1984-01-13 1989-04-14 Anic Spa Analoghi retro-invertiti esapeptidici c-terminali della sostanza p.
JPS617209A (ja) * 1984-06-20 1986-01-13 Meiji Seika Kaisha Ltd 育毛剤組成物
IT1178786B (it) * 1984-12-21 1987-09-16 Assorenti Analoghi retro-inverso parzialmente modificati della neurotensina
IT1184164B (it) * 1985-03-19 1987-10-22 Eniricerche Spa Triptidi ad azione ipotensiva e procedimento per la loro sintesi
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
IT1196500B (it) * 1986-07-16 1988-11-16 Eniricerche Spa Derivati dell'acido malonico e metodi per la loro sintesi
DE3783280T2 (de) * 1986-07-16 1993-05-06 Eniricerche Spa Teilweise retro-invertierte analoge des tuftsin, methode zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
US5877277A (en) 1987-09-24 1999-03-02 Biomeasure, Inc. Octapeptide bombesin analogs
US6218364B1 (en) * 1988-06-20 2001-04-17 Scott L. Harbeson Fluorinated neurokinin A antagonists
US5830863A (en) * 1988-06-20 1998-11-03 Merrell Pharmaceuticals Inc. Neurokinin A antagonists
IT1228451B (it) * 1989-02-22 1991-06-19 Sclavo S P A Siena Nuovi derivati diamminici geminali e loro impiego nelle sintesi di peptidi retro-inversi
IE77033B1 (en) * 1989-08-16 1997-11-19 Univ Tulane Substance P antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862114A (en) * 1971-11-22 1975-01-21 Ici Australia Ltd Analogs of substance p
JPS5411293A (en) * 1977-05-23 1979-01-27 Toyo Soda Mfg Co Ltd Recovery of protease

Also Published As

Publication number Publication date
JPS58116443A (ja) 1983-07-11
DE3261304D1 (en) 1985-01-03
ATE10364T1 (de) 1984-12-15
IT1212508B (it) 1989-11-22
CA1249698A (en) 1989-01-31
EP0082568A3 (en) 1983-10-26
EP0082568B1 (en) 1984-11-21
US4439360A (en) 1984-03-27
EP0082568A2 (en) 1983-06-29

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