ATE84545T1 - Derivate des alpha-anp und ihre herstellung. - Google Patents

Derivate des alpha-anp und ihre herstellung.

Info

Publication number
ATE84545T1
ATE84545T1 AT87308586T AT87308586T ATE84545T1 AT E84545 T1 ATE84545 T1 AT E84545T1 AT 87308586 T AT87308586 T AT 87308586T AT 87308586 T AT87308586 T AT 87308586T AT E84545 T1 ATE84545 T1 AT E84545T1
Authority
AT
Austria
Prior art keywords
alpha
gly
arg
hydrogen
production
Prior art date
Application number
AT87308586T
Other languages
English (en)
Inventor
Masahiko Fujino
Mitsuhiro Wakimasu
Kohei Nishikawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE84545T1 publication Critical patent/ATE84545T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C07K14/582—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT87308586T 1987-09-29 1987-09-29 Derivate des alpha-anp und ihre herstellung. ATE84545T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87308586A EP0269220B1 (de) 1986-09-29 1987-09-29 Derivate des alpha-ANP und ihre Herstellung
JP5231429A JPH0726436A (ja) 1993-09-17 1993-09-17 人工芝用パイルおよびその製造方法

Publications (1)

Publication Number Publication Date
ATE84545T1 true ATE84545T1 (de) 1993-01-15

Family

ID=16923426

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87308586T ATE84545T1 (de) 1987-09-29 1987-09-29 Derivate des alpha-anp und ihre herstellung.

Country Status (6)

Country Link
US (1) US5159061A (de)
EP (1) EP0269220B1 (de)
JP (2) JP2508755B2 (de)
AT (1) ATE84545T1 (de)
CA (1) CA1339678C (de)
DE (1) DE3783579T2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0246795A3 (de) * 1986-05-20 1990-04-04 Advanced Peptide Development Limited Synthetische natriuretische Peptide
US5565606A (en) * 1986-10-21 1996-10-15 Hoechst Aktiengesellschaft Synthesis of peptide aminoalkylamides and peptide hydrazides by the solid-phase method
DE3723551A1 (de) * 1987-07-16 1989-01-26 Hoechst Ag Peptide mit vasorelaxierender, natriuretischer und diuretischer wirkung, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
US5047397A (en) * 1988-08-26 1991-09-10 California Biotechnology Inc. Linear analogs of atrial natriuretic peptides
JP2855143B2 (ja) * 1987-12-24 1999-02-10 サイオス インコーポレイテッド 心房の，ナトリウム排出亢進性ペプチドの直鎖アナログ
JP2873586B2 (ja) * 1988-07-15 1999-03-24 武田薬品工業株式会社 抗体およびこれを用いる免疫化学的測定方法
WO1990005103A1 (en) * 1988-11-03 1990-05-17 Prime Technology A sheet feeding apparatus
JPH06256387A (ja) * 1991-06-14 1994-09-13 Suetsuna Yoko 新規なペプチド、その製法およびそれを有効成分とする 血圧降下剤
US5846932A (en) * 1993-11-12 1998-12-08 Genentech, Inc. Receptor specific atrial natriuretic peptides
US6525022B1 (en) 1993-11-12 2003-02-25 Genentech, Inc. Receptor specific atrial natriuretic peptides
US5665704A (en) * 1993-11-12 1997-09-09 Genentech, Inc. Receptor specific atrial natriuretic peptides
BRPI0709427A2 (pt) * 2006-03-30 2011-07-12 Palatin Technologies Inc "construto cìclico, composição farmacêutica e uso de um composto
EP2004633A4 (de) * 2006-03-30 2009-08-26 Palatin Technologies Inc Lineare natriuretische peptidkonstrukte
US8580746B2 (en) * 2006-03-30 2013-11-12 Palatin Technologies, Inc. Amide linkage cyclic natriuretic peptide constructs

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5178029A (de) * 1974-12-27 1976-07-07 Mitsubishi Rayon Co
JPS5421477A (en) * 1977-07-20 1979-02-17 Nitto Boseki Co Ltd Rotating disc of reinforced plastic
JPS5841955A (ja) * 1981-08-31 1983-03-11 関島　唯雄 水引用巻着フイルムの製造方法
AU572173B2 (en) * 1983-08-29 1988-05-05 Institut De Recherches Cliniques De Montreal Natriuretic factors
US4508712A (en) * 1984-01-10 1985-04-02 Washington University Atrial peptide
JPH0780907B2 (ja) * 1984-04-19 1995-08-30 シオス・ノバ・インク 新規な心房性ナトリウム尿排泄亢進性及び血管拡張性ポリペプチド
JPS60259646A (ja) * 1984-06-01 1985-12-21 帝人株式会社 嵩高混繊糸
AU600652B2 (en) * 1984-06-08 1990-08-23 Hisayuki Matsuo Human atrial natriuretic peptide and gene encoding same
JPS617260U (ja) * 1984-06-19 1986-01-17 国産電機株式会社 電動機
JPH0672157B2 (ja) * 1984-08-29 1994-09-14 味の素株式会社 新規ペプチド
JPS61286400A (ja) * 1985-06-14 1986-12-16 Ajinomoto Co Inc 新規ペプチド
US4670540A (en) * 1984-08-29 1987-06-02 Ajinomoto Co., Inc. Novel peptide
JPS61233698A (ja) * 1985-04-09 1986-10-17 Ajinomoto Co Inc 新規ペプチド
DE3443257A1 (de) * 1984-11-28 1986-05-28 Bissendorf Peptide GmbH, 3002 Wedemark Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap)
JPS61161299A (ja) * 1985-01-04 1986-07-21 メルク　エンド　カムパニ−　インコ−ポレ−テツド 心房ペプチド
JPS61280400A (ja) * 1985-06-04 1986-12-10 三菱電機株式会社 アクテイブ近接信管
US4757048A (en) * 1985-11-05 1988-07-12 Biotechnology Research Associates J.V. Synthetic analogs of atrial natriuretic peptides
WO1987002674A1 (en) * 1985-11-05 1987-05-07 Biotechnology Research Associates, J.V. Analogs of atrial natriuretic peptides
DE3614833A1 (de) * 1986-01-16 1987-07-23 Hoechst Ag Peptide mit vasorelaxierender, natriuretischer und diuretischer wirkung, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
EP0232078A3 (de) * 1986-01-31 1990-03-14 Merck & Co. Inc. Peptide mit ANF-Wirkung
EP0246795A3 (de) * 1986-05-20 1990-04-04 Advanced Peptide Development Limited Synthetische natriuretische Peptide

Also Published As

Publication number Publication date
CA1339678C (en) 1998-02-17
EP0269220A3 (en) 1990-05-23
JP2508755B2 (ja) 1996-06-19
DE3783579T2 (de) 1993-05-13
US5159061A (en) 1992-10-27
EP0269220B1 (de) 1993-01-13
JPS63179891A (ja) 1988-07-23
JPH0726436A (ja) 1995-01-27
DE3783579D1 (de) 1993-02-25
EP0269220A2 (de) 1988-06-01

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