IT1211792B - O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia - Google Patents
O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessiaInfo
- Publication number
- IT1211792B IT1211792B IT8748404A IT4840487A IT1211792B IT 1211792 B IT1211792 B IT 1211792B IT 8748404 A IT8748404 A IT 8748404A IT 4840487 A IT4840487 A IT 4840487A IT 1211792 B IT1211792 B IT 1211792B
- Authority
- IT
- Italy
- Prior art keywords
- amino
- hydroxypropansulphonic
- adaptity
- alcanoil
- anticonvulsive
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- -1 AMINO Chemical class 0.000 title 1
- 230000002082 anti-convulsion Effects 0.000 title 1
- 206010015037 epilepsy Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8748404A IT1211792B (it) | 1987-09-21 | 1987-09-21 | O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia |
| EP88830373A EP0309421B1 (en) | 1987-09-21 | 1988-09-19 | O-alkanoyl derivatives of 3-amino-2-hydroxypropanesulfonic acid having anticonvulsivant activity and pharmaceutical compositions containing same for the therapeutical treatment of epilepsy |
| AT88830373T ATE82567T1 (de) | 1987-09-21 | 1988-09-19 | 0-alkanoyl-derivate der 3-amino-2hydroxypropanesulfons|ure mit antikonvulsiver wirkung und diese enthaltende pharmazeutische mittel zur therapeutischen behandlung der epilepsie. |
| DE8888830373T DE3876058T2 (de) | 1987-09-21 | 1988-09-19 | 0-alkanoyl-derivate der 3-amino-2-hydroxypropanesulfonsaeure mit antikonvulsiver wirkung und diese enthaltende pharmazeutische mittel zur therapeutischen behandlung der epilepsie. |
| ES88830373T ES2052776T3 (es) | 1987-09-21 | 1988-09-19 | Derivados o-alcanoilo del acido 3-amino-2-hidroxipropansulfonico con actividad anticonvulsiva y composiciones farmaceuticas que los contienen para el tratamiento terapeutico de epilepsia. |
| JP63237456A JPH01102055A (ja) | 1987-09-21 | 1988-09-21 | 3−アミノ−2−ヒドロキシプロパンスルホン酸の0−アルカノイル誘導体 |
| GR920402754T GR3006385T3 (it) | 1987-09-21 | 1992-11-30 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8748404A IT1211792B (it) | 1987-09-21 | 1987-09-21 | O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8748404A0 IT8748404A0 (it) | 1987-09-21 |
| IT1211792B true IT1211792B (it) | 1989-11-03 |
Family
ID=11266349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8748404A IT1211792B (it) | 1987-09-21 | 1987-09-21 | O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0309421B1 (it) |
| JP (1) | JPH01102055A (it) |
| AT (1) | ATE82567T1 (it) |
| DE (1) | DE3876058T2 (it) |
| ES (1) | ES2052776T3 (it) |
| GR (1) | GR3006385T3 (it) |
| IT (1) | IT1211792B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040208875A1 (en) | 1995-03-15 | 2004-10-21 | Queen's University At Kingston | Method for treating amyloidosis |
| US7414076B2 (en) | 2003-06-23 | 2008-08-19 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US7244764B2 (en) | 2003-06-23 | 2007-07-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| US20070010573A1 (en) | 2003-06-23 | 2007-01-11 | Xianqi Kong | Methods and compositions for treating amyloid-related diseases |
| AU2004251717B2 (en) * | 2003-06-23 | 2010-03-11 | Bellus Health (International) Limited | Treatment of amyloid- and epileptogenesis-associated diseases |
| WO2006085149A2 (en) | 2004-12-22 | 2006-08-17 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
| TW200716088A (en) | 2005-04-15 | 2007-05-01 | Neurochem Int Ltd | Formulations and methods for treating amyloidosis |
| AU2006342958A1 (en) | 2005-12-22 | 2007-11-08 | Bellus Health (International) Limited | Treatment of renal disorders, diabetic nephropathy and dyslipidemias |
| SI2089417T1 (sl) | 2006-10-12 | 2015-04-30 | Bhi Limited Partnership | Metode, spojine, sestavki in vektorji za dostavo 3-amino-1-propansulfonske kisline |
| AU2009276343A1 (en) | 2008-08-01 | 2010-02-04 | Bioxiness Pharmaceuticals, Inc. | Methionine analogs and methods of using same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1419097A (en) * | 1973-03-27 | 1975-12-24 | Procter & Gamble Ltd | Preparation of sulphobetaines |
| US4246194A (en) * | 1977-12-08 | 1981-01-20 | Research Organics, Inc. | Amino-hydroxy-alkyl sulfonic acid-zwitterions |
| DE3337026A1 (de) * | 1983-10-12 | 1985-04-25 | Henkel KGaA, 4000 Düsseldorf | Aminoxidsulfonate |
| DE3673099D1 (de) * | 1985-05-09 | 1990-09-06 | Sherex Chem | Alkalivertraegliche amphoterische sulfobetain-tenside. |
| US4891159A (en) * | 1986-08-27 | 1990-01-02 | Miranol Inc. | Low-foam alkali-stable amphoteric surface active agents |
-
1987
- 1987-09-21 IT IT8748404A patent/IT1211792B/it active
-
1988
- 1988-09-19 EP EP88830373A patent/EP0309421B1/en not_active Expired - Lifetime
- 1988-09-19 AT AT88830373T patent/ATE82567T1/de not_active IP Right Cessation
- 1988-09-19 ES ES88830373T patent/ES2052776T3/es not_active Expired - Lifetime
- 1988-09-19 DE DE8888830373T patent/DE3876058T2/de not_active Expired - Fee Related
- 1988-09-21 JP JP63237456A patent/JPH01102055A/ja active Granted
-
1992
- 1992-11-30 GR GR920402754T patent/GR3006385T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0309421A2 (en) | 1989-03-29 |
| ATE82567T1 (de) | 1992-12-15 |
| JPH0565503B2 (it) | 1993-09-17 |
| ES2052776T3 (es) | 1994-07-16 |
| JPH01102055A (ja) | 1989-04-19 |
| EP0309421B1 (en) | 1992-11-19 |
| DE3876058T2 (de) | 1993-03-25 |
| IT8748404A0 (it) | 1987-09-21 |
| EP0309421A3 (en) | 1990-05-02 |
| GR3006385T3 (it) | 1993-06-21 |
| DE3876058D1 (de) | 1992-12-24 |
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