IT8321083A1 - ANALOGHI RETRO-INVERTITI DEL PENTAPEPTIDE POTENZIANTE LA BRADICHININA BPP5a E METODI PER LA LORO PREPARAZIONE - Google Patents

ANALOGHI RETRO-INVERTITI DEL PENTAPEPTIDE POTENZIANTE LA BRADICHININA BPP5a E METODI PER LA LORO PREPARAZIONE

Info

Publication number
IT8321083A1
IT8321083A1 IT1983A21083A IT2108383A IT8321083A1 IT 8321083 A1 IT8321083 A1 IT 8321083A1 IT 1983A21083 A IT1983A21083 A IT 1983A21083A IT 2108383 A IT2108383 A IT 2108383A IT 8321083 A1 IT8321083 A1 IT 8321083A1
Authority
IT
Italy
Prior art keywords
bpp5a
bradiquinine
pentapeptide
retro
analogs
Prior art date
Application number
IT1983A21083A
Other languages
English (en)
Other versions
IT1164225B (it
IT8321083A0 (it
Original Assignee
Anic Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anic Spa filed Critical Anic Spa
Publication of IT8321083A0 publication Critical patent/IT8321083A0/it
Priority to IT8321083A priority Critical patent/IT1164225B/it
Priority to AT84200658T priority patent/ATE54154T1/de
Priority to DE8484200658T priority patent/DE3482589D1/de
Priority to EP84200658A priority patent/EP0128602B1/en
Priority to EP88201526A priority patent/EP0301639A3/en
Priority to CA000453932A priority patent/CA1252949A/en
Priority to US06/608,985 priority patent/US4522752A/en
Priority to AU27914/84A priority patent/AU571225B2/en
Priority to JP59094760A priority patent/JPH0635477B2/ja
Publication of IT8321083A1 publication Critical patent/IT8321083A1/it
Application granted granted Critical
Publication of IT1164225B publication Critical patent/IT1164225B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
IT8321083A 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione IT1164225B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione
EP88201526A EP0301639A3 (en) 1983-05-13 1984-05-08 Analogues of the bradykinin potentiating peptide bpp 5a and methods for their preparation
DE8484200658T DE3482589D1 (de) 1983-05-13 1984-05-08 Retro-inverse analoga des bradykinin-potentialisierenden peptids bpp-5a und verfahren zu ihrer herstellung.
EP84200658A EP0128602B1 (en) 1983-05-13 1984-05-08 Retro-inverso analogues of the bradykinin potentiating peptide bpp5a and method for their preparation
AT84200658T ATE54154T1 (de) 1983-05-13 1984-05-08 Retro-inverse analoga des bradykininpotentialisierenden peptids bpp-5a und verfahren zu ihrer herstellung.
CA000453932A CA1252949A (en) 1983-05-13 1984-05-09 Retro-inverso analogues of the bradykinin potentiating peptide bpp in5a xx and method for their preparation
US06/608,985 US4522752A (en) 1983-05-13 1984-05-10 Retro-inverso analogues of the bradykinin potentiating peptide BPP5a and methods for their preparation
AU27914/84A AU571225B2 (en) 1983-05-13 1984-05-11 Retro-inverso analogues of the bradykinin potentiating peptide bpp 5a
JP59094760A JPH0635477B2 (ja) 1983-05-13 1984-05-14 ペプチド及びその製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione

Publications (3)

Publication Number Publication Date
IT8321083A0 IT8321083A0 (it) 1983-05-13
IT8321083A1 true IT8321083A1 (it) 1984-11-13
IT1164225B IT1164225B (it) 1987-04-08

Family

ID=11176481

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8321083A IT1164225B (it) 1983-05-13 1983-05-13 Analoghi retro-invertiti del pentapeptide potenziante la bradichina bpp5a e metodi per la loro preparazione

Country Status (8)

Country Link
US (1) US4522752A (it)
EP (2) EP0128602B1 (it)
JP (1) JPH0635477B2 (it)
AT (1) ATE54154T1 (it)
AU (1) AU571225B2 (it)
CA (1) CA1252949A (it)
DE (1) DE3482589D1 (it)
IT (1) IT1164225B (it)

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IT1178789B (it) * 1984-12-21 1987-09-16 Assorenti Peptidi retro-invertiti analoghi del potenziatore della bradichinina bpp 5a
IT1184317B (it) * 1985-02-05 1987-10-28 Eniricerche Spa Retro-inverso analoghi del peptide potenziatore della bradichina bpp5a
IT1184164B (it) * 1985-03-19 1987-10-22 Eniricerche Spa Triptidi ad azione ipotensiva e procedimento per la loro sintesi
IT1190389B (it) * 1985-09-19 1988-02-16 Eniricerche Spa Esapeptidi ad attivita' ipotensiva
EP0667786B1 (en) * 1992-08-27 2004-01-21 Deakin Research Limited Retro-, inverso-, and retro-inverso synthetic peptide analogues
US5968895A (en) 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
DE04029691T1 (de) * 1998-02-02 2007-11-08 Trustees Of Tufts College, Medford Verwendung von Dipetidylpeptidasehemmer zur Regulierung des Glukosemetabolismus
US6465495B1 (en) 1998-07-30 2002-10-15 Osi Pharmaceuticals, Inc. Preparation of pyridone-based phosphotyrosine mimetics and uses thereof
US6984719B1 (en) 1998-09-17 2006-01-10 Hospital Sainte-Justine Peptide antagonists of prostaglandin F2α receptor
US7396905B1 (en) 1999-05-21 2008-07-08 Mckeon Frank Calcipressins: endogenous inhibitors of calcineurin, uses and reagents related thereto
US20040235749A1 (en) * 1999-09-15 2004-11-25 Sylvain Chemtob G-protein coupled receptor antagonists
US6560542B1 (en) * 2000-01-24 2003-05-06 The Cielo Institute Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
US6865492B2 (en) * 2000-01-24 2005-03-08 The Cielo Institute, Inc. Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
US20050119454A1 (en) * 2000-01-24 2005-06-02 The Cielo Institute, Inc. Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
BR0101088A (pt) * 2001-03-19 2003-03-18 Biolab Sanus Farmaceutica Ltda Processo de isolamento e purificação de peptìdeos inibidores das vasopeptidases, com especificidade para o sìtio carboxìlico da enzima conversora da angiotensina, secretados pelas glândulas do veneno de serpentes (bpps), particularmente bothrops jararaca, ou produzidos endogenamente (evasins) possuindo ação vasodilatadora e anti-hipertensiva; processo de determinação da sequência de amido-ácidos dos peptìdios inibidores secretados pela glândula de veneno de serpentes (bpps) ou endógenos (evasins); processo de determinação da sequência de aminoácidos dos bpps por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca. processo de determinação da sequência de aminoácidos dos evasins por dedução do cdna dos precursores dessas moléculas expressos em tecidos de serpentes, especificamente bothrops jararaca, processo de amplificação do cdna a partir das bibliotecas de cdna de pâncreas e/ou cérebro de serpentes, especificamente bothrops jararaca; processo de sìntese em fase sólida de peptìdeos inibidores das vasopeptidases com ação vasodilatadora e anti-hipertensiva, peptìdeos inibidores das vasopeptidases com ação anti-hipertensiva; utilização dos peptìdeos inibidores das vaso peptidases com ação vasodilatadora e anti-hipertensiva na obtenção de composições farmacêuticas; processo de determinação da atividade inibitória sobre as vasopeptidases e de atividade biológica sobre músculo liso, sistema cardiovascular e microcirculatório.
IL161121A0 (en) 2001-10-03 2004-08-31 Harvard College Copolymers for suppression of autoimmune diseases, and methods of use
WO2003045977A2 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Peptidomimetic Inhibitors of Post-Proline Cleaving Enzymes
CA2466870A1 (en) * 2001-11-26 2003-06-05 Trustees Of Tufts College Methods for treating autoimmune disorders, and reagents related thereto
US6935959B2 (en) * 2002-05-16 2005-08-30 Microsoft Corporation Use of multiple player real-time voice communications on a gaming device
US7521530B2 (en) 2002-06-11 2009-04-21 Universite De Montreal Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
DK1697399T3 (en) 2003-12-12 2017-03-06 Government Of The United States Of America As Repr By The Secr Of The Dept Of Health And Human Servi Human cytotoxic t lymphocyte epitope and its agonist epitope from the non-variable number of muc-1 tandem repeat sequences
US7491263B2 (en) 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
CA2573720A1 (en) 2004-07-14 2006-02-23 University Of Utah Research Foundation Netrin-related compositions and uses
DE102004037356B4 (de) * 2004-07-30 2017-11-23 Ansaldo Energia Ip Uk Limited Wandstruktur zur Begrenzung eines Heißgaspfads
MX2007005870A (es) 2004-11-17 2007-10-10 Joanne Mclauring Composiciones que comprenden derivados de escilo-inositol y metodos para tratar trastornos de agregacion de proteinas.
GB0426146D0 (en) 2004-11-29 2004-12-29 Bioxell Spa Therapeutic peptides and method
KR20070120967A (ko) 2005-02-25 2007-12-26 유니버시티 오브 유타 리서치 파운데이션 내피 세포 부착 또는 이동을 촉진시키는 트로포엘라스틴
EP2298792A3 (en) 2005-08-05 2011-10-19 Pharmagap Inc. Peptides targeted to protein kinase C isoforms and uses thereof
US8921050B2 (en) * 2006-03-17 2014-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of diagnosing renal cell carcinoma
US8470963B2 (en) 2006-06-30 2013-06-25 Sku Asset Management Gmbh Multifunctional compounds for pharmaceutical purposes
AU2008238577B2 (en) 2007-04-12 2015-02-19 Waratah Pharmaceuticals Inc. Use of cyclohexanehexol derivatives in the treatment of ocular diseases
KR101561709B1 (ko) * 2007-06-27 2015-10-22 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 올리고펩티드 티로시나제 억제제 및 그의 용도
CN101795703B (zh) * 2007-06-27 2015-05-06 里兰斯坦福初级大学理事会 肽酪氨酸酶抑制剂及其应用
WO2009013319A1 (en) * 2007-07-23 2009-01-29 Bioxell Spa Screening, therapy and diagnosis
GB0821941D0 (en) 2008-12-01 2009-01-07 Renovo Ltd Non-surgical improvements of scars
US9296805B2 (en) 2009-06-18 2016-03-29 Dana-Farber Cancer Institute, Inc. Stabilized insulinotropic peptides and methods of use
JP6025871B2 (ja) 2012-01-26 2016-11-16 クリストファー ジェイ． ソアレス ペプチドホルモンのカルシトニンｃｇｒｐファミリーのペプチドアンタゴニスト及びその使用
US9637527B2 (en) 2012-03-13 2017-05-02 James Cook University Method for treating inflammation with an Ac-TMP-2 protein
US10017551B2 (en) 2013-03-15 2018-07-10 The Regents Of The University Of California Peptides having reduced toxicity that stimulate cholesterol efflux
US20160235813A1 (en) 2013-09-18 2016-08-18 James Cook University Anti-inflammatory proteins and methods of use
CA2988299C (en) 2015-06-05 2023-10-31 Ibio, Inc. Endostatin fragments and variants for use in treating fibrosis
GB201609083D0 (en) 2016-05-24 2016-07-06 Syntab Therapeutics Gmbh Synthetic compound
CA3035561A1 (en) 2016-09-02 2018-03-08 Christopher J. Soares Use of cgrp receptor antagonists in neuroprotection and neurological disorders
WO2018215831A2 (en) 2017-05-22 2018-11-29 National Hellenic Research Foundation Macrocyclic modulators of disease associated protein misfolding and aggregation

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CH568964A5 (it) * 1972-06-01 1975-11-14 Squibb & Sons Inc
HU185263B (en) * 1981-06-12 1984-12-28 Richter Gedeon Vegyeszet Process for producing peptides effective on the immuncontroll analogous with the tp5
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
IT1190891B (it) * 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
ZA838780B (en) * 1982-11-26 1985-01-30 Nyegaard & Co As Peptide compounds
IT1164240B (it) * 1983-05-25 1987-04-08 Anic Spa Decapeptide parzialmente retro-invertito inibitore specifico della renina con elevata resistenza alla idrolisi enzimatica
IT1206339B (it) * 1984-01-13 1989-04-14 Anic Spa Analoghi retro-invertiti esapeptidici c-terminali della sostanza p.

Also Published As

Publication number Publication date
EP0128602B1 (en) 1990-06-27
EP0128602A3 (en) 1987-01-14
AU571225B2 (en) 1988-04-14
ATE54154T1 (de) 1990-07-15
IT1164225B (it) 1987-04-08
JPS59212453A (ja) 1984-12-01
AU2791484A (en) 1984-11-15
IT8321083A0 (it) 1983-05-13
CA1252949A (en) 1989-04-18
US4522752A (en) 1985-06-11
EP0301639A3 (en) 1989-10-18
DE3482589D1 (de) 1990-08-02
JPH0635477B2 (ja) 1994-05-11
EP0301639A2 (en) 1989-02-01
EP0128602A2 (en) 1984-12-19

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