JP2010514698A5 - - Google Patents
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- JP2010514698A5 JP2010514698A5 JP2009543249A JP2009543249A JP2010514698A5 JP 2010514698 A5 JP2010514698 A5 JP 2010514698A5 JP 2009543249 A JP2009543249 A JP 2009543249A JP 2009543249 A JP2009543249 A JP 2009543249A JP 2010514698 A5 JP2010514698 A5 JP 2010514698A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- seq
- fragment
- sequence
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 67
- 229920001184 polypeptide Polymers 0.000 claims 65
- 102000004196 processed proteins & peptides Human genes 0.000 claims 65
- 239000012634 fragment Substances 0.000 claims 42
- 238000000034 method Methods 0.000 claims 24
- 210000004027 cell Anatomy 0.000 claims 20
- 241000196324 Embryophyta Species 0.000 claims 17
- 108091033319 polynucleotide Proteins 0.000 claims 17
- 102000040430 polynucleotide Human genes 0.000 claims 17
- 239000002157 polynucleotide Substances 0.000 claims 17
- 230000005875 antibody response Effects 0.000 claims 13
- 230000003472 neutralizing effect Effects 0.000 claims 12
- 241000710886 West Nile virus Species 0.000 claims 9
- 208000015181 infectious disease Diseases 0.000 claims 9
- 230000002458 infectious effect Effects 0.000 claims 9
- 230000004044 response Effects 0.000 claims 6
- 241000700605 Viruses Species 0.000 claims 5
- 150000001413 amino acids Chemical class 0.000 claims 5
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 4
- 230000028993 immune response Effects 0.000 claims 4
- 239000013598 vector Substances 0.000 claims 4
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 3
- 230000007124 immune defense Effects 0.000 claims 3
- 238000003018 immunoassay Methods 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 2
- 241000208125 Nicotiana Species 0.000 claims 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 210000001236 prokaryotic cell Anatomy 0.000 claims 2
- 238000003127 radioimmunoassay Methods 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 230000001131 transforming effect Effects 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 238000004220 aggregation Methods 0.000 claims 1
- 230000002776 aggregation Effects 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 238000004587 chromatography analysis Methods 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 230000001268 conjugating effect Effects 0.000 claims 1
- 241001233957 eudicotyledons Species 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 238000005206 flow analysis Methods 0.000 claims 1
- 230000002068 genetic effect Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000001114 immunoprecipitation Methods 0.000 claims 1
- 230000002480 immunoprotective effect Effects 0.000 claims 1
- 230000010354 integration Effects 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003550 marker Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 238000000159 protein binding assay Methods 0.000 claims 1
- 239000013603 viral vector Substances 0.000 claims 1
- 238000001262 western blot Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87151806P | 2006-12-22 | 2006-12-22 | |
| PCT/US2007/088512 WO2008143713A2 (en) | 2006-12-22 | 2007-12-21 | Plant-made west nile virus (wnv) vaccines, vectors and plant codon optimized sequences |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010514698A JP2010514698A (ja) | 2010-05-06 |
| JP2010514698A5 true JP2010514698A5 (enExample) | 2011-04-07 |
Family
ID=40032322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009543249A Pending JP2010514698A (ja) | 2006-12-22 | 2007-12-21 | 植物によって製造されるウエストナイルウイルス(wnv)ワクチン、ベクターおよび植物コドン最適化配列 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7888069B2 (enExample) |
| EP (1) | EP2099916A2 (enExample) |
| JP (1) | JP2010514698A (enExample) |
| AR (1) | AR064500A1 (enExample) |
| AU (1) | AU2007353773A1 (enExample) |
| BR (1) | BRPI0721141A2 (enExample) |
| CA (1) | CA2671934A1 (enExample) |
| WO (1) | WO2008143713A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2663627T3 (es) | 2010-10-11 | 2018-04-16 | Jennewein Biotechnologie Gmbh | Fucosiltransferasas novedosas y sus aplicaciones |
| WO2012095874A1 (en) | 2011-01-11 | 2012-07-19 | Enneffe S.R.L. | Adjustable anti -theft device |
| WO2013191997A1 (en) * | 2012-06-18 | 2013-12-27 | Dow Agrosciences Llc | Expression of maize codon optimized proteins in pseudomonas fluorescens |
| GB201704126D0 (en) * | 2017-03-15 | 2017-04-26 | Blom Nihlén Kim Andrea | Vaccine |
| US12443985B2 (en) | 2022-12-16 | 2025-10-14 | Sap Se | Solving sparse data problems in a recommendation system with cold start |
| US12430678B2 (en) * | 2022-12-16 | 2025-09-30 | Sap Se | Solving sparse data problems in a recommendation system with freezing start |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5428147A (en) | 1983-04-15 | 1995-06-27 | Mycogen Plant Science, Inc. | Octopine T-DNA promoters |
| US5380831A (en) | 1986-04-04 | 1995-01-10 | Mycogen Plant Science, Inc. | Synthetic insecticidal crystal protein gene |
| US5276268A (en) | 1986-08-23 | 1994-01-04 | Hoechst Aktiengesellschaft | Phosphinothricin-resistance gene, and its use |
| US5637489A (en) | 1986-08-23 | 1997-06-10 | Hoechst Aktiengesellschaft | Phosphinothricin-resistance gene, and its use |
| US5273894A (en) | 1986-08-23 | 1993-12-28 | Hoechst Aktiengesellschaft | Phosphinothricin-resistance gene, and its use |
| US5336603A (en) | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
| DE3924454A1 (de) | 1989-07-24 | 1991-02-07 | Cornelis P Prof Dr Hollenberg | Die anwendung von dna und dna-technologie fuer die konstruktion von netzwerken zur verwendung in der chip-konstruktion und chip-produktion (dna chips) |
| US5073627A (en) | 1989-08-22 | 1991-12-17 | Immunex Corporation | Fusion proteins comprising GM-CSF and IL-3 |
| CA2071943C (en) | 1989-12-22 | 2007-04-24 | Joan Tellefsen Odell | Site-specific recombination of dna in plant cells |
| US5183740A (en) | 1990-02-23 | 1993-02-02 | The United States Of America As Represented By The Secretary Of The Navy | Flow immunosensor method and apparatus |
| US5384253A (en) | 1990-12-28 | 1995-01-24 | Dekalb Genetics Corporation | Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes |
| IL99120A0 (en) | 1991-08-07 | 1992-07-15 | Yeda Res & Dev | Multimers of the soluble forms of tnf receptors,their preparation and pharmaceutical compositions containing them |
| US6419931B1 (en) | 1991-08-26 | 2002-07-16 | Epimmune Inc. | Compositions and methods for eliciting CTL immunity |
| US6025165A (en) | 1991-11-25 | 2000-02-15 | Enzon, Inc. | Methods for producing multivalent antigen-binding proteins |
| DK0617706T3 (da) | 1991-11-25 | 2001-11-12 | Enzon Inc | Multivalente antigenbindende proteiner |
| TW261517B (enExample) | 1991-11-29 | 1995-11-01 | Mitsubishi Shozi Kk | |
| US5643570A (en) | 1992-05-19 | 1997-07-01 | Xoma Corporation | BPI-immunoglobulin fusion proteins |
| US6239328B1 (en) | 1992-10-05 | 2001-05-29 | North Carolina State University | Method for reducing expression variability of transgenes in plant cells |
| ES2176208T3 (es) | 1992-10-05 | 2002-12-01 | Univ North Carolina State | Metodo para incrementar la expresion y para reducir la variabilidad de expresion de genes foraneos en celulas vegetales. |
| NZ257942A (en) | 1992-10-23 | 1996-04-26 | Immunex Corp | Preparing a mammalian protein by expression of a fusion protein containing a leucine zipper domain |
| WO1994012520A1 (en) | 1992-11-20 | 1994-06-09 | Enzon, Inc. | Linker for linked fusion polypeptides |
| FI92882C (fi) | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
| US5753439A (en) | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
| US5843464A (en) | 1995-06-02 | 1998-12-01 | The Ohio State University | Synthetic chimeric fimbrin peptides |
| US5750352A (en) | 1995-08-23 | 1998-05-12 | The Johns Hopkins University | Mono-allelic mutation analysis for identifying germline mutations |
| US5773695A (en) | 1996-01-26 | 1998-06-30 | North Carolina State University | Plant nuclear scaffold attachment region and method for increasing gene expression in transgenic cells |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| WO1998049305A1 (en) | 1997-05-01 | 1998-11-05 | Amgen Inc. | Chimeric opg polypeptides |
| US6214545B1 (en) | 1997-05-05 | 2001-04-10 | Third Wave Technologies, Inc | Polymorphism analysis by nucleic acid structure probing |
| JP4198315B2 (ja) | 1997-08-05 | 2008-12-17 | ヌベンタ バイオファーマスティカル コーポレイション | Hpv抗原およびストレスタンパク質またはこれらのタンパク質の発現が可能な発現ベクターを含む組成物によって誘起されるhpv抗原に対する免疫応答 |
| US6319691B1 (en) | 1999-06-15 | 2001-11-20 | Usa Universe Bioengineering, Inc. | Fusion proteins comprising IFN-alpha2b and TM-alpha1 |
| US6342362B1 (en) | 1999-08-05 | 2002-01-29 | Daniel S. Mytelka | Methods and compositions for the purification of proteins or other macromolecules |
| WO2004045529A2 (en) * | 2002-11-15 | 2004-06-03 | Acambis, Inc. | West nile virus vaccine |
| JP2007526215A (ja) | 2003-05-05 | 2007-09-13 | ダウ アグロサイエンス リミテッド ライアビリティー カンパニー | トランスジェニック植物細胞に由来する安定な免疫予防的および治療的組成物ならびにその産生方法 |
| US8475808B2 (en) | 2003-05-23 | 2013-07-02 | Novartis Vaccines And Diagnostics, Inc. | Immunogenic reagents from west nile virus |
| US20080034455A1 (en) * | 2004-05-21 | 2008-02-07 | Simon Fraser University | Production Of A Protein Localized To The Endoplasmic Reticulum Protein Bodies In A Transgenic Plant And Seed |
-
2007
- 2007-12-21 EP EP07874382A patent/EP2099916A2/en not_active Withdrawn
- 2007-12-21 AU AU2007353773A patent/AU2007353773A1/en not_active Abandoned
- 2007-12-21 JP JP2009543249A patent/JP2010514698A/ja active Pending
- 2007-12-21 US US11/962,924 patent/US7888069B2/en not_active Expired - Fee Related
- 2007-12-21 WO PCT/US2007/088512 patent/WO2008143713A2/en not_active Ceased
- 2007-12-21 BR BRPI0721141-4A patent/BRPI0721141A2/pt not_active Application Discontinuation
- 2007-12-21 CA CA002671934A patent/CA2671934A1/en not_active Abandoned
- 2007-12-21 AR ARP070105865A patent/AR064500A1/es not_active Application Discontinuation
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