JP2013531477A5 - - Google Patents
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- JP2013531477A5 JP2013531477A5 JP2013509178A JP2013509178A JP2013531477A5 JP 2013531477 A5 JP2013531477 A5 JP 2013531477A5 JP 2013509178 A JP2013509178 A JP 2013509178A JP 2013509178 A JP2013509178 A JP 2013509178A JP 2013531477 A5 JP2013531477 A5 JP 2013531477A5
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- Prior art keywords
- amino acid
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- 125000003275 alpha amino acid group Chemical class 0.000 claims 36
- 108090000765 processed proteins & peptides Proteins 0.000 claims 33
- 229920001184 polypeptide Polymers 0.000 claims 32
- 102000004196 processed proteins & peptides Human genes 0.000 claims 32
- 102000007562 Serum Albumin Human genes 0.000 claims 5
- 108010071390 Serum Albumin Proteins 0.000 claims 5
- 230000004927 fusion Effects 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 210000004899 c-terminal region Anatomy 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 102100037362 Fibronectin Human genes 0.000 claims 2
- 102000002090 Fibronectin type III Human genes 0.000 claims 2
- 108050009401 Fibronectin type III Proteins 0.000 claims 2
- 108010067306 Fibronectins Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 102000009027 Albumins Human genes 0.000 claims 1
- 108010088751 Albumins Proteins 0.000 claims 1
- 102000003973 Fibroblast growth factor 21 Human genes 0.000 claims 1
- 108090000376 Fibroblast growth factor 21 Proteins 0.000 claims 1
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 241000282560 Macaca mulatta Species 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33067210P | 2010-05-03 | 2010-05-03 | |
| US61/330,672 | 2010-05-03 | ||
| US13/098,851 | 2011-05-02 | ||
| US13/098,851 US8969289B2 (en) | 2010-05-03 | 2011-05-02 | Serum albumin binding molecules |
| PCT/US2011/034998 WO2011140086A2 (en) | 2010-05-03 | 2011-05-03 | Serum albumin binding molecules |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015210912A Division JP6219357B2 (ja) | 2010-05-03 | 2015-10-27 | 血清アルブミン結合性分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013531477A JP2013531477A (ja) | 2013-08-08 |
| JP2013531477A5 true JP2013531477A5 (enExample) | 2014-06-19 |
| JP5876872B2 JP5876872B2 (ja) | 2016-03-02 |
Family
ID=44628186
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013509178A Expired - Fee Related JP5876872B2 (ja) | 2010-05-03 | 2011-05-03 | 血清アルブミン結合性分子 |
| JP2015210912A Expired - Fee Related JP6219357B2 (ja) | 2010-05-03 | 2015-10-27 | 血清アルブミン結合性分子 |
| JP2017185708A Pending JP2018057368A (ja) | 2010-05-03 | 2017-09-27 | 血清アルブミン結合性分子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015210912A Expired - Fee Related JP6219357B2 (ja) | 2010-05-03 | 2015-10-27 | 血清アルブミン結合性分子 |
| JP2017185708A Pending JP2018057368A (ja) | 2010-05-03 | 2017-09-27 | 血清アルブミン結合性分子 |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US8969289B2 (enExample) |
| EP (1) | EP2566888A2 (enExample) |
| JP (3) | JP5876872B2 (enExample) |
| KR (1) | KR101854931B1 (enExample) |
| CN (2) | CN103003301B (enExample) |
| AR (1) | AR081459A1 (enExample) |
| AU (1) | AU2011248273B2 (enExample) |
| BR (1) | BR112012028162A2 (enExample) |
| CA (1) | CA2798510A1 (enExample) |
| CL (1) | CL2012003077A1 (enExample) |
| CO (1) | CO6630173A2 (enExample) |
| EA (1) | EA029334B1 (enExample) |
| IL (1) | IL222832A0 (enExample) |
| MX (2) | MX2012012800A (enExample) |
| PE (1) | PE20130593A1 (enExample) |
| SG (2) | SG185091A1 (enExample) |
| TN (1) | TN2012000518A1 (enExample) |
| TW (1) | TW201138808A (enExample) |
| UY (1) | UY33366A (enExample) |
| WO (1) | WO2011140086A2 (enExample) |
| ZA (1) | ZA201209091B (enExample) |
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| PL2068909T3 (pl) | 2007-03-30 | 2012-09-28 | Ambrx Inc | Modyfikowane polipeptydy fgf-21 i ich zastosowanie |
| KR20100128291A (ko) | 2008-02-14 | 2010-12-07 | 브리스톨-마이어스 스큅 컴퍼니 | Ｅｇｆｒ에 결합하는 조작된 단백질을 기초로 하는 표적화된 치료제 |
| CN102099373A (zh) | 2008-05-22 | 2011-06-15 | 百时美施贵宝公司 | 基于纤连蛋白的多价支架结构域蛋白 |
| EP3412300A1 (en) * | 2008-06-27 | 2018-12-12 | Duke University | Therapeutic agents comprising elastin-like peptides |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子 |
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| US9475850B2 (en) * | 2010-06-05 | 2016-10-25 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
| US9139629B2 (en) | 2010-06-05 | 2015-09-22 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
| US20130331329A1 (en) | 2011-02-24 | 2013-12-12 | The Trustees Of The University Of Pennsylvania | Biomarkers for seizures |
| WO2012122464A1 (en) * | 2011-03-10 | 2012-09-13 | New York University | Methods and compositions for modulating tnf/tnfr signaling |
| EP2697257B1 (en) | 2011-04-13 | 2016-10-19 | Bristol-Myers Squibb Company | Fc fusion proteins comprising novel linkers or arrangements |
| US20140187488A1 (en) | 2011-05-17 | 2014-07-03 | Bristol-Myers Squibb Company | Methods for maintaining pegylation of polypeptides |
| EP2710382B1 (en) | 2011-05-17 | 2017-10-18 | Bristol-Myers Squibb Company | Improved methods for the selection of binding proteins |
| CN104271588B (zh) * | 2011-07-08 | 2017-10-10 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| US9522951B2 (en) | 2011-10-31 | 2016-12-20 | Bristol-Myers Squibb Company | Fibronectin binding domains with reduced immunogenicity |
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| TW201536814A (zh) | 2013-07-25 | 2015-10-01 | Novartis Ag | 用於治療心臟衰竭之合成環狀多肽 |
| CN103550790B (zh) * | 2013-11-04 | 2016-01-27 | 上海交通大学医学院附属瑞金医院 | 骨膜蛋白抗体及其在药物制备中的应用 |
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