JP2008519592A5 - - Google Patents
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- Publication number
- JP2008519592A5 JP2008519592A5 JP2007540681A JP2007540681A JP2008519592A5 JP 2008519592 A5 JP2008519592 A5 JP 2008519592A5 JP 2007540681 A JP2007540681 A JP 2007540681A JP 2007540681 A JP2007540681 A JP 2007540681A JP 2008519592 A5 JP2008519592 A5 JP 2008519592A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- peptide
- lysine
- arginine
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 239000004472 Lysine Substances 0.000 claims 12
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 12
- 239000004475 Arginine Substances 0.000 claims 10
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 10
- 235000018417 cysteine Nutrition 0.000 claims 8
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 8
- 150000001413 amino acids Chemical class 0.000 claims 6
- 235000001014 amino acid Nutrition 0.000 claims 5
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 108091006116 chimeric peptides Proteins 0.000 claims 4
- 108020001507 fusion proteins Proteins 0.000 claims 4
- 230000003834 intracellular effect Effects 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 4
- 102000037865 fusion proteins Human genes 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 150000008574 D-amino acids Chemical class 0.000 claims 1
- 101710118867 Maurocalcin Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000003902 lesion Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0412045 | 2004-11-12 | ||
| FR0412045A FR2877946B1 (fr) | 2004-11-12 | 2004-11-12 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
| PCT/FR2005/002817 WO2006051224A1 (fr) | 2004-11-12 | 2005-11-14 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008519592A JP2008519592A (ja) | 2008-06-12 |
| JP2008519592A5 true JP2008519592A5 (enExample) | 2008-12-18 |
| JP5416901B2 JP5416901B2 (ja) | 2014-02-12 |
Family
ID=34953760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007540681A Expired - Fee Related JP5416901B2 (ja) | 2004-11-12 | 2005-11-14 | 興味のある分子の細胞内位置決めのためのベクターとして用いられるマウロカルシン由来ペプチド |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8207293B2 (enExample) |
| EP (1) | EP1814905B1 (enExample) |
| JP (1) | JP5416901B2 (enExample) |
| CN (1) | CN101094863A (enExample) |
| AU (1) | AU2005303623A1 (enExample) |
| CA (1) | CA2586811A1 (enExample) |
| FR (1) | FR2877946B1 (enExample) |
| IL (1) | IL183022A0 (enExample) |
| WO (1) | WO2006051224A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2537858A1 (en) | 2011-06-20 | 2012-12-26 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Small efficient cell penetrating peptides derived from the scorpion toxin maurocalcine |
| WO2014141124A1 (en) | 2013-03-13 | 2014-09-18 | Institut National De La Sante Et De La Recherche Medicale | Erk-pathway activating compound for preventing or treating leptin resistance |
| US9777274B2 (en) | 2013-03-15 | 2017-10-03 | Techulon Inc. | Antisense molecules for treatment of staphylococcus aureus infection |
| KR20160021076A (ko) | 2013-03-15 | 2016-02-24 | 테출론 인코포레이티드 | 스타필로코커스 아우레우스 감염의 치료를 위한 안티센스 분자 |
| EP3007717B1 (en) | 2013-06-12 | 2018-08-29 | Pharis Biotec GmbH | Peptides with antagonistic activities against natural cxcr4 |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| CN105087492B (zh) * | 2015-07-16 | 2021-04-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 培养原代海马神经元的方法 |
| CN108135970B (zh) | 2015-09-09 | 2023-09-01 | 弗莱德哈钦森癌症中心 | 软骨归巢肽 |
| WO2017100700A2 (en) * | 2015-12-11 | 2017-06-15 | Fred Hutchinson Cancer Research Center | Peptides for renal therapy |
| AU2018210157B2 (en) | 2017-01-18 | 2022-10-06 | Fred Hutchinson Cancer Center | Peptide compositions and methods of use thereof for disrupting TEAD interactions |
| EP3595699A4 (en) | 2017-03-16 | 2020-12-23 | Blaze Bioscience, Inc. | PEPTIDIC CONJUGATES OF CARTILAGE ECOTROPISM AND THEIR METHODS OF USE |
| CA3064436A1 (en) | 2017-06-15 | 2018-12-20 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
| AU2018388583A1 (en) | 2017-12-19 | 2020-06-11 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6051429A (en) * | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| FR2739621B1 (fr) | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
| NZ510539A (en) | 1998-09-15 | 2003-06-30 | Nizo Food Res | A chromatographic process for producing peptides from biological fluids such as milk, whey, blood, egg white and cell culture extracts |
| GB0005124D0 (en) * | 2000-03-03 | 2000-04-26 | Cellpep Sa | Maurocalcin,analogues thereof and their therapeutical uses |
| ATE458745T1 (de) * | 2002-06-10 | 2010-03-15 | Amylin Pharmaceuticals Inc | Nachspaltige sulfurentschützung zur konvergenten proteinherstellung beim verfahren von chemischer ligation |
| SE0201863D0 (en) | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
-
2004
- 2004-11-12 FR FR0412045A patent/FR2877946B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-14 CN CNA2005800457088A patent/CN101094863A/zh active Pending
- 2005-11-14 AU AU2005303623A patent/AU2005303623A1/en not_active Abandoned
- 2005-11-14 JP JP2007540681A patent/JP5416901B2/ja not_active Expired - Fee Related
- 2005-11-14 US US11/719,171 patent/US8207293B2/en not_active Expired - Fee Related
- 2005-11-14 WO PCT/FR2005/002817 patent/WO2006051224A1/fr not_active Ceased
- 2005-11-14 CA CA002586811A patent/CA2586811A1/fr not_active Abandoned
- 2005-11-14 EP EP05817457.4A patent/EP1814905B1/fr not_active Expired - Lifetime
-
2007
- 2007-05-06 IL IL183022A patent/IL183022A0/en unknown
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