JP2005509160A5 - - Google Patents
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- Publication number
- JP2005509160A5 JP2005509160A5 JP2003542928A JP2003542928A JP2005509160A5 JP 2005509160 A5 JP2005509160 A5 JP 2005509160A5 JP 2003542928 A JP2003542928 A JP 2003542928A JP 2003542928 A JP2003542928 A JP 2003542928A JP 2005509160 A5 JP2005509160 A5 JP 2005509160A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- polypeptide
- functional derivative
- binding
- test compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 8
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 241000711549 Hepacivirus C Species 0.000 claims 3
- 101000740659 Homo sapiens Scavenger receptor class B member 1 Proteins 0.000 claims 3
- 102000051417 human SCARB1 Human genes 0.000 claims 3
- 239000005557 antagonist Substances 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34450401P | 2001-11-09 | 2001-11-09 | |
| PCT/EP2002/012272 WO2003040726A2 (en) | 2001-11-09 | 2002-11-01 | Screening for hepatitis c virus entry inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005509160A JP2005509160A (ja) | 2005-04-07 |
| JP2005509160A5 true JP2005509160A5 (enExample) | 2006-01-05 |
Family
ID=23350803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003542928A Withdrawn JP2005509160A (ja) | 2001-11-09 | 2002-11-01 | Ｃ型肝炎ウイルス侵入阻害剤のスクリーニング |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050019751A1 (enExample) |
| EP (1) | EP1444523B1 (enExample) |
| JP (1) | JP2005509160A (enExample) |
| AT (1) | ATE491952T1 (enExample) |
| CA (1) | CA2465731A1 (enExample) |
| DE (1) | DE60238633D1 (enExample) |
| WO (1) | WO2003040726A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0315248D0 (en) * | 2003-06-30 | 2003-08-06 | Hoffmann La Roche | HCV regulated protein expression |
| EP1765869B1 (en) * | 2004-07-08 | 2015-05-20 | JV Bio S.r.l | Antigen binding proteins directed against scavenger receptor b1 that inhibit hcv replication |
| WO2006103493A1 (en) * | 2005-03-29 | 2006-10-05 | Epixis | Methods for enhancing the potency of hcv neutralizing antibodies |
| EP1991215A1 (en) * | 2006-03-09 | 2008-11-19 | Cenix Bioscience GmbH | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases |
| EP1832283A1 (en) * | 2006-03-09 | 2007-09-12 | Cenix Bioscience GmbH | Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases |
| WO2008013918A2 (en) * | 2006-07-26 | 2008-01-31 | Myelin Repair Foundation, Inc. | Cell cycle regulation and differentiation |
| US9052321B2 (en) * | 2008-10-03 | 2015-06-09 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Flavivirus-based system for production of hepatitis C virus (HCV) |
| CN108349853B (zh) * | 2015-11-12 | 2022-03-15 | 沙特基础工业全球技术公司 | 生产芳烃和烯烃的方法 |
| CN112121168B (zh) * | 2020-04-09 | 2022-03-04 | 中国人民解放军军事科学院军事医学研究院 | 一种抑制剂在制备治疗SARS-CoV-2肺炎及其并发症的药物中的应用 |
| JP2025531751A (ja) * | 2022-09-07 | 2025-09-25 | ユナイテッド キングダム リサーチ アンド イノベーション | 代謝関連疾患のための治療薬 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1270939B (it) * | 1993-05-11 | 1997-05-26 | Angeletti P Ist Richerche Bio | Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili. |
| US5925333A (en) * | 1995-11-15 | 1999-07-20 | Massachusetts Institute Of Technology | Methods for modulation of lipid uptake |
| US5998141A (en) * | 1997-07-10 | 1999-12-07 | Millennium Pharmaceuticals, Inc. | Intronic and polymorphic SR-BI nucleic acids and uses therefor |
-
2002
- 2002-11-01 US US10/494,555 patent/US20050019751A1/en not_active Abandoned
- 2002-11-01 DE DE60238633T patent/DE60238633D1/de not_active Expired - Lifetime
- 2002-11-01 WO PCT/EP2002/012272 patent/WO2003040726A2/en not_active Ceased
- 2002-11-01 JP JP2003542928A patent/JP2005509160A/ja not_active Withdrawn
- 2002-11-01 EP EP02802643A patent/EP1444523B1/en not_active Expired - Lifetime
- 2002-11-01 CA CA002465731A patent/CA2465731A1/en not_active Abandoned
- 2002-11-01 AT AT02802643T patent/ATE491952T1/de not_active IP Right Cessation
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