ATE491952T1 - Screening auf inhibitoren des eindringens von hepatitis-c-virus - Google Patents

Screening auf inhibitoren des eindringens von hepatitis-c-virus

Info

Publication number
ATE491952T1
ATE491952T1 AT02802643T AT02802643T ATE491952T1 AT E491952 T1 ATE491952 T1 AT E491952T1 AT 02802643 T AT02802643 T AT 02802643T AT 02802643 T AT02802643 T AT 02802643T AT E491952 T1 ATE491952 T1 AT E491952T1
Authority
AT
Austria
Prior art keywords
screening
methods
hepatitis
inhibitors
cell
Prior art date
Application number
AT02802643T
Other languages
German (de)
English (en)
Inventor
Riccardo Cortese
Elisa Scarselli
Alessandra Vitelli
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE491952T1 publication Critical patent/ATE491952T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02802643T 2001-11-09 2002-11-01 Screening auf inhibitoren des eindringens von hepatitis-c-virus ATE491952T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34450401P 2001-11-09 2001-11-09
PCT/EP2002/012272 WO2003040726A2 (en) 2001-11-09 2002-11-01 Screening for hepatitis c virus entry inhibitors

Publications (1)

Publication Number Publication Date
ATE491952T1 true ATE491952T1 (de) 2011-01-15

Family

ID=23350803

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02802643T ATE491952T1 (de) 2001-11-09 2002-11-01 Screening auf inhibitoren des eindringens von hepatitis-c-virus

Country Status (7)

Country Link
US (1) US20050019751A1 (enExample)
EP (1) EP1444523B1 (enExample)
JP (1) JP2005509160A (enExample)
AT (1) ATE491952T1 (enExample)
CA (1) CA2465731A1 (enExample)
DE (1) DE60238633D1 (enExample)
WO (1) WO2003040726A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315248D0 (en) * 2003-06-30 2003-08-06 Hoffmann La Roche HCV regulated protein expression
US7928193B2 (en) * 2004-07-08 2011-04-19 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Antigen binding proteins directed against scavenger receptor B1 that inhibit HCV replication
WO2006103493A1 (en) * 2005-03-29 2006-10-05 Epixis Methods for enhancing the potency of hcv neutralizing antibodies
EP1832283A1 (en) * 2006-03-09 2007-09-12 Cenix Bioscience GmbH Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases
WO2007101710A1 (en) * 2006-03-09 2007-09-13 Cenix Bioscience Gmbh Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases
WO2008013918A2 (en) * 2006-07-26 2008-01-31 Myelin Repair Foundation, Inc. Cell cycle regulation and differentiation
US9052321B2 (en) * 2008-10-03 2015-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Flavivirus-based system for production of hepatitis C virus (HCV)
CN108349853B (zh) * 2015-11-12 2022-03-15 沙特基础工业全球技术公司 生产芳烃和烯烃的方法
CN112121168B (zh) * 2020-04-09 2022-03-04 中国人民解放军军事科学院军事医学研究院 一种抑制剂在制备治疗SARS-CoV-2肺炎及其并发症的药物中的应用
CN120035665A (zh) * 2022-09-07 2025-05-23 英国研究与创新署 用于代谢相关疾病的治疗剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270939B (it) * 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
US5925333A (en) * 1995-11-15 1999-07-20 Massachusetts Institute Of Technology Methods for modulation of lipid uptake
US5998141A (en) * 1997-07-10 1999-12-07 Millennium Pharmaceuticals, Inc. Intronic and polymorphic SR-BI nucleic acids and uses therefor

Also Published As

Publication number Publication date
WO2003040726A2 (en) 2003-05-15
EP1444523B1 (en) 2010-12-15
CA2465731A1 (en) 2003-05-15
EP1444523A2 (en) 2004-08-11
DE60238633D1 (de) 2011-01-27
WO2003040726A3 (en) 2003-12-18
US20050019751A1 (en) 2005-01-27
JP2005509160A (ja) 2005-04-07

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Legal Events

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