BR0311223A - Método para o uso de derivados de piranindol para tratar infecção pelo vìrus da hepatite c - Google Patents
Método para o uso de derivados de piranindol para tratar infecção pelo vìrus da hepatite cInfo
- Publication number
- BR0311223A BR0311223A BR0311223-3A BR0311223A BR0311223A BR 0311223 A BR0311223 A BR 0311223A BR 0311223 A BR0311223 A BR 0311223A BR 0311223 A BR0311223 A BR 0311223A
- Authority
- BR
- Brazil
- Prior art keywords
- pyranindol
- derivatives
- virus infection
- treat hepatitis
- hepatitis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"MéTODO PARA O USO DE DERIVADOS DE PIRANINDOL PARA TRATAR INFECçãO PELO VìRUS DA HEPATITE C". A presente invenção refere-se a métodos de tratamento, prevenção ou inibição de infecção viral Hepatite C em um mamífero compreendendo contato do mamífero de uma quantidade eficaz de um composto da fórmula: em que as substituições em R~ 1~, R~ 2~, R~ 3~ - R~ 12~ e Y são apresentadas no relatório descritivo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38215402P | 2002-05-21 | 2002-05-21 | |
US45870603P | 2003-03-28 | 2003-03-28 | |
PCT/US2003/016294 WO2003099275A1 (en) | 2002-05-21 | 2003-05-21 | Method for the use of pyranoindole derivatives to treat infection with hepatitis c virus |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0311223A true BR0311223A (pt) | 2005-03-15 |
Family
ID=29586949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0311223-3A BR0311223A (pt) | 2002-05-21 | 2003-05-21 | Método para o uso de derivados de piranindol para tratar infecção pelo vìrus da hepatite c |
Country Status (11)
Country | Link |
---|---|
US (1) | US7217730B2 (pt) |
EP (1) | EP1509225A1 (pt) |
JP (1) | JP2005531572A (pt) |
CN (1) | CN1655778A (pt) |
AR (1) | AR040089A1 (pt) |
AU (1) | AU2003239593A1 (pt) |
BR (1) | BR0311223A (pt) |
CA (1) | CA2485972A1 (pt) |
MX (1) | MXPA04011162A (pt) |
TW (1) | TW200400818A (pt) |
WO (1) | WO2003099275A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1718608T3 (da) | 2004-02-20 | 2013-10-14 | Boehringer Ingelheim Int | Virale polymeraseinhibitorer |
CA2557160A1 (en) * | 2004-03-01 | 2005-09-15 | Viropharma Incorporated | Pyranoindole derivatives and the use thereof for the treatment of hepatitis c virus infection or disease |
WO2008024763A2 (en) * | 2006-08-25 | 2008-02-28 | Wyeth | Identification and characterization of hcv replicon variants with reduced susceptibility to hcv-796, and methods related thereto |
CN102872461A (zh) | 2007-05-04 | 2013-01-16 | 弗特克斯药品有限公司 | 用于治疗hcv感染的组合治疗 |
US20120177601A1 (en) * | 2009-07-02 | 2012-07-12 | The Usa As Represented By The Secretary Of The Department Of Veterans Affairs | Treatment of hepatitis c virus infections |
TWI625121B (zh) | 2009-07-13 | 2018-06-01 | 基利科學股份有限公司 | 調節細胞凋亡信號之激酶的抑制劑 |
WO2014003694A1 (en) * | 2012-06-25 | 2014-01-03 | Kucukguzel S Guniz | Synthesis of thiosemicarbazides and triazoles derived from etodolac |
EP2864333B1 (en) * | 2012-06-25 | 2017-07-19 | Kucukguzel, S. Guniz | Etodolac derivatives as hcv ns5b polymerase inhibitors |
EP2738173A1 (en) * | 2012-11-28 | 2014-06-04 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Heterocyclic compounds as inhibitors of the sodium iodide symporter |
CN103864803A (zh) * | 2012-12-07 | 2014-06-18 | 天津科技大学 | 一种1-(苯基)-1,3,4,9-四氢吡喃并[3,4-b]吲哚衍生物的制备及其抗肿瘤药物中的应用 |
EP3693366B8 (en) | 2014-12-23 | 2023-08-09 | Gilead Sciences, Inc. | Processes for preparing ask1 inhibitors |
JP2019001715A (ja) * | 2015-10-30 | 2019-01-10 | 協和発酵キリン株式会社 | 三環性化合物 |
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US3939178A (en) | 1971-06-01 | 1976-02-17 | American Home Products Corporation | Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles |
US3843681A (en) | 1971-06-01 | 1974-10-22 | American Home Prod | 1-carboxamido pyrano(thiopyrano)(3,4-6)indole derivatives |
US3974179A (en) | 1971-06-01 | 1976-08-10 | American Home Products Corporation | 1,3,4,9-Tetrahydropyrano[3,4-b]indole-1-acetamides and derivatives |
US3880853A (en) | 1972-01-13 | 1975-04-29 | Ayerst Mckenna & Harrison | Pyrano-and thiopyranoindole |
US4076831A (en) | 1972-05-16 | 1978-02-28 | American Home Products Corporation | Pyrano[3,4-b]-indole derivatives, pharmaceutical compositions and methods of use |
US4036842A (en) | 1972-05-16 | 1977-07-19 | American Home Products Corporation | Process for preparing polycyclic heterocycles having a pyran ring |
US4012417A (en) | 1972-05-16 | 1977-03-15 | American Home Products Corporation | Process for preparing pyrano[3,4-b]indole or thio pyrano[3,4-b]indole derivatives |
US4070371A (en) | 1972-05-16 | 1978-01-24 | American Home Products Corporation | Derivatives of 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid |
US4118394A (en) | 1976-10-18 | 1978-10-03 | Ayerst, Mckenna & Harrison Limited | Pyrano- and thiopyranoindole derivatives |
US4179503A (en) | 1978-05-08 | 1979-12-18 | American Home Products Corp. | 1-Hydroxyalkanamine pyrano[3,4-b]indole derivatives |
US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
US4503901A (en) | 1982-10-05 | 1985-03-12 | Vinogradov Viktor N | Squeezing caster |
US4515961A (en) | 1983-08-16 | 1985-05-07 | American Home Products Corporation | Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4,-b] indole-1-acetic acid using enrichment crystallization |
US4501899A (en) | 1983-08-16 | 1985-02-26 | American Home Products Corporation | Resolution of (+)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cholesteryl aniline |
US4520203A (en) | 1983-08-16 | 1985-05-28 | American Home Products Corporation | Resolution of (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid using cinchonine |
US4544757A (en) | 1984-02-16 | 1985-10-01 | American Home Products Corporation | Process for the resolution of pyrano[3,4-b]indole-1-acetic acids |
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-
2003
- 2003-05-19 TW TW092113460A patent/TW200400818A/zh unknown
- 2003-05-20 US US10/441,984 patent/US7217730B2/en not_active Expired - Fee Related
- 2003-05-21 BR BR0311223-3A patent/BR0311223A/pt not_active Application Discontinuation
- 2003-05-21 MX MXPA04011162A patent/MXPA04011162A/es unknown
- 2003-05-21 CN CNA038116340A patent/CN1655778A/zh active Pending
- 2003-05-21 WO PCT/US2003/016294 patent/WO2003099275A1/en active Search and Examination
- 2003-05-21 JP JP2004506799A patent/JP2005531572A/ja active Pending
- 2003-05-21 AU AU2003239593A patent/AU2003239593A1/en not_active Abandoned
- 2003-05-21 CA CA002485972A patent/CA2485972A1/en not_active Abandoned
- 2003-05-21 EP EP03734147A patent/EP1509225A1/en not_active Withdrawn
- 2003-05-21 AR ARP030101761A patent/AR040089A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
TW200400818A (en) | 2004-01-16 |
WO2003099275A1 (en) | 2003-12-04 |
AU2003239593A1 (en) | 2003-12-12 |
JP2005531572A (ja) | 2005-10-20 |
CA2485972A1 (en) | 2003-12-04 |
CN1655778A (zh) | 2005-08-17 |
MXPA04011162A (es) | 2005-02-17 |
US7217730B2 (en) | 2007-05-15 |
AR040089A1 (es) | 2005-03-16 |
EP1509225A1 (en) | 2005-03-02 |
US20040082643A1 (en) | 2004-04-29 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |