ATE302002T1 - Verwendung von pyrazolderivaten zur behandlung von unfruchtbarkeit - Google Patents
Verwendung von pyrazolderivaten zur behandlung von unfruchtbarkeitInfo
- Publication number
- ATE302002T1 ATE302002T1 AT01939143T AT01939143T ATE302002T1 AT E302002 T1 ATE302002 T1 AT E302002T1 AT 01939143 T AT01939143 T AT 01939143T AT 01939143 T AT01939143 T AT 01939143T AT E302002 T1 ATE302002 T1 AT E302002T1
- Authority
- AT
- Austria
- Prior art keywords
- pyrazole derivatives
- treat infertility
- compounds
- infertility
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20581400P | 2000-05-19 | 2000-05-19 | |
PCT/US2001/016189 WO2001087287A2 (en) | 2000-05-19 | 2001-05-19 | Use of pyrazole derivatives for treating infertility |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE302002T1 true ATE302002T1 (de) | 2005-09-15 |
Family
ID=22763739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01939143T ATE302002T1 (de) | 2000-05-19 | 2001-05-19 | Verwendung von pyrazolderivaten zur behandlung von unfruchtbarkeit |
Country Status (11)
Country | Link |
---|---|
US (2) | US6914069B2 (de) |
EP (1) | EP1282418B1 (de) |
JP (1) | JP4371295B2 (de) |
AT (1) | ATE302002T1 (de) |
AU (2) | AU6469401A (de) |
CA (1) | CA2405507A1 (de) |
DE (1) | DE60112742T2 (de) |
ES (1) | ES2243504T3 (de) |
IL (1) | IL152097A0 (de) |
PT (1) | PT1282418E (de) |
WO (1) | WO2001087287A2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005504093A (ja) * | 2001-09-27 | 2005-02-10 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 内因性テストステロンレベルの増加方法 |
DK1908463T3 (da) * | 2001-12-14 | 2011-11-28 | Merck Serono Sa | Fremgangsmåder til at inducere ægløsning ved anvendelse af en ikke polypeptid-CAMP-niveaumodulator |
WO2004016592A1 (en) * | 2002-08-14 | 2004-02-26 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
US6649638B1 (en) * | 2002-08-14 | 2003-11-18 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
EP1797072A4 (de) * | 2004-09-17 | 2009-09-09 | Exelixis Inc | Pyrazolkinasemodulatoren und verwendungsverfahren |
US20080167322A1 (en) * | 2005-02-16 | 2008-07-10 | Pinkerton Anthony B | Substituted Pyrazoles as Modulators of Chemokine Receptors |
UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
US20110009463A1 (en) * | 2007-10-17 | 2011-01-13 | Yuri Karl Petersson | Geranylgeranyl transferase inhibitors and methods of making and using the same |
JP2012516344A (ja) * | 2009-01-30 | 2012-07-19 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー | 結晶質n−{(1s)−2−アミノ−1−[(3−フルオロフェニル)メチル]エチル}−5−クロロ−4−(4−クロロ−1−メチル−1h−ピラゾール−5−イル)−2−チオフェンカルボキサミド塩酸塩 |
WO2011161615A1 (en) | 2010-06-24 | 2011-12-29 | Ranbaxy Laboratories Limited | 5-lipoxygenase inhibitors |
AR088020A1 (es) | 2010-06-30 | 2014-05-07 | Ironwood Pharmaceuticals Inc | Compuestos heterociclicos como estimuladores de sgc |
WO2012003476A2 (en) * | 2010-07-02 | 2012-01-05 | Ventana Medical Systems, Inc. | Hapten conjugates for target detection |
CN103402515B (zh) | 2010-11-09 | 2017-05-17 | 铁木医药有限公司 | sGC刺激剂 |
WO2013046041A1 (en) * | 2011-09-30 | 2013-04-04 | Synovo Gmbh | Pyridinylpyrazoles for use as kinase modulators for the treatment of cancer |
CA2861804C (en) | 2011-12-27 | 2021-10-26 | Ironwood Pharmaceuticals, Inc. | 2-benzyl,3(pyrimidin-2-yl)substituted pyrazoles useful as sgc stimulators |
US10287251B2 (en) * | 2015-06-23 | 2019-05-14 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivative or pharmaceutically acceptable salt thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3842088A (en) * | 1973-01-31 | 1974-10-15 | Sandoz Ag | Substituted naphtho pyrazoles |
US5639639A (en) | 1983-11-02 | 1997-06-17 | Genzyme Corporation | Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof |
GB8410899D0 (en) * | 1984-04-27 | 1984-06-06 | Ici Plc | Phenol derivatives |
IT1206302B (it) | 1987-06-26 | 1989-04-14 | Serono Cesare Ist Ricerca | Ormone follicolo-stimolante urinario |
US5017557A (en) | 1987-07-24 | 1991-05-21 | Industria Farmaceutica Serono S.P.A. | Treatment of infertility with somatotrophin releasing factor |
FR2665898B1 (fr) | 1990-08-20 | 1994-03-11 | Sanofi | Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant. |
DE4039733A1 (de) | 1990-12-13 | 1992-06-17 | Basf Ag | Substituierte 5-aminopyrazole |
US5869688A (en) | 1994-07-20 | 1999-02-09 | Monsanto Company | Preparation of substituted 3-aryl-5-haloalkyl-pyrazoles having herbicidal activity |
WO1997012884A1 (en) | 1995-10-04 | 1997-04-10 | Fmc Corporation | Herbicidal 6-heterocyclic indazole derivatives |
AU4945697A (en) | 1996-10-09 | 1998-05-05 | Novartis Ag | Solid phase synthesis of heterocyclic compounds |
CA2270469C (en) * | 1996-11-19 | 2007-04-10 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents |
DE19746749C2 (de) | 1997-10-23 | 1999-12-02 | Bosch Gmbh Robert | Einrichtung zum Verriegeln und Entriegeln einer Tür |
US6191147B1 (en) * | 1998-12-24 | 2001-02-20 | Ppd Discovery, Inc. | Pyrazole compounds and uses thereof |
US20030060494A1 (en) * | 2001-05-18 | 2003-03-27 | Nobuyuki Yasuda | Pharmaceutical use of N-carbamoylazole derivatives |
JP2005504093A (ja) * | 2001-09-27 | 2005-02-10 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | 内因性テストステロンレベルの増加方法 |
-
2001
- 2001-05-19 JP JP2001583755A patent/JP4371295B2/ja not_active Expired - Fee Related
- 2001-05-19 CA CA002405507A patent/CA2405507A1/en not_active Abandoned
- 2001-05-19 WO PCT/US2001/016189 patent/WO2001087287A2/en active IP Right Grant
- 2001-05-19 ES ES01939143T patent/ES2243504T3/es not_active Expired - Lifetime
- 2001-05-19 IL IL15209701A patent/IL152097A0/xx unknown
- 2001-05-19 EP EP01939143A patent/EP1282418B1/de not_active Expired - Lifetime
- 2001-05-19 DE DE60112742T patent/DE60112742T2/de not_active Expired - Lifetime
- 2001-05-19 AU AU6469401A patent/AU6469401A/xx active Pending
- 2001-05-19 PT PT01939143T patent/PT1282418E/pt unknown
- 2001-05-19 AU AU2001264694A patent/AU2001264694B8/en not_active Ceased
- 2001-05-19 AT AT01939143T patent/ATE302002T1/de active
- 2001-05-19 US US09/860,658 patent/US6914069B2/en not_active Expired - Fee Related
-
2004
- 2004-08-19 US US10/921,471 patent/US7456201B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU6469401A (en) | 2001-11-26 |
EP1282418A2 (de) | 2003-02-12 |
US6914069B2 (en) | 2005-07-05 |
US20050026985A1 (en) | 2005-02-03 |
IL152097A0 (en) | 2003-05-29 |
JP4371295B2 (ja) | 2009-11-25 |
ES2243504T3 (es) | 2005-12-01 |
AU2001264694B8 (en) | 2006-05-04 |
WO2001087287A3 (en) | 2002-05-16 |
AU2001264694B2 (en) | 2006-01-05 |
WO2001087287A2 (en) | 2001-11-22 |
US20020132844A1 (en) | 2002-09-19 |
EP1282418B1 (de) | 2005-08-17 |
JP2004501100A (ja) | 2004-01-15 |
US7456201B2 (en) | 2008-11-25 |
PT1282418E (pt) | 2005-10-31 |
DE60112742T2 (de) | 2006-02-02 |
CA2405507A1 (en) | 2001-11-22 |
DE60112742D1 (de) | 2005-09-22 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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