ATE333869T1 - Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen - Google Patents

Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen

Info

Publication number
ATE333869T1
ATE333869T1 AT02711840T AT02711840T ATE333869T1 AT E333869 T1 ATE333869 T1 AT E333869T1 AT 02711840 T AT02711840 T AT 02711840T AT 02711840 T AT02711840 T AT 02711840T AT E333869 T1 ATE333869 T1 AT E333869T1
Authority
AT
Austria
Prior art keywords
mglur5 antagonists
pruritic conditions
treat
treat pruritic
conditions
Prior art date
Application number
AT02711840T
Other languages
English (en)
Inventor
Fabrizio Gasparini
Laszlo Urban
Josef Gottfried Meingassner
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE333869T1 publication Critical patent/ATE333869T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02711840T 2001-02-07 2002-02-06 Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen ATE333869T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0103045.1A GB0103045D0 (en) 2001-02-07 2001-02-07 Organic Compounds

Publications (1)

Publication Number Publication Date
ATE333869T1 true ATE333869T1 (de) 2006-08-15

Family

ID=9908300

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02711840T ATE333869T1 (de) 2001-02-07 2002-02-06 Verwendung von mglur5 antagonisten zur behandlung von pruritischen zuständen

Country Status (13)

Country Link
US (2) US20040106582A1 (de)
EP (1) EP1359905B1 (de)
JP (2) JP2004517947A (de)
CN (1) CN1253151C (de)
AT (1) ATE333869T1 (de)
AU (1) AU2002231777A1 (de)
BR (1) BR0206917A (de)
CA (1) CA2433409C (de)
DE (1) DE60213365T2 (de)
ES (1) ES2271229T3 (de)
GB (1) GB0103045D0 (de)
PT (1) PT1359905E (de)
WO (1) WO2002062323A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0128996D0 (en) * 2001-12-04 2002-01-23 Novartis Ag Organic compounds
GB0322612D0 (en) * 2003-09-26 2003-10-29 Novartis Ag Organic compounds
CN1870999A (zh) * 2003-10-31 2006-11-29 阿斯利康(瑞典)有限公司 炔烃ⅰ
CA2549969A1 (en) * 2003-10-31 2005-05-19 Astrazeneca Ab Alkynes ii
WO2005044265A1 (en) * 2003-10-31 2005-05-19 Astrazeneca Ab Alkynes iii
GB0503646D0 (en) * 2005-02-22 2005-03-30 Novartis Ag Organic compounds
GB0508319D0 (en) 2005-04-25 2005-06-01 Novartis Ag Organic compounds
KR20150047609A (ko) 2012-08-30 2015-05-04 니뽄 신야쿠 가부시키가이샤 피리딘 유도체 및 의약
KR102035048B1 (ko) * 2015-06-03 2019-10-22 에프. 호프만-라 로슈 아게 에틴일 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013744B1 (en) * 1989-12-29 1994-09-20 Allegran Inc Acetylenes disubstituted with a pyridinyl group and a substituted phenyl group having retinoid like activity
FR2719044B1 (fr) * 1994-04-26 1996-05-31 Cird Galderma Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
US5534641A (en) * 1994-12-29 1996-07-09 Allergan Acetylenes disubstituted with 2-tetrahydropyranoxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
US5498795A (en) * 1994-12-29 1996-03-12 Allergan, Inc. Acetylenes disubstituted with hydroxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
TW544448B (en) * 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
US6774138B2 (en) * 1999-08-31 2004-08-10 Merck & Co., Inc. Thiazolyl(pyridyl)ethyne compounds

Also Published As

Publication number Publication date
CN1535143A (zh) 2004-10-06
AU2002231777A1 (en) 2002-08-19
JP2004517947A (ja) 2004-06-17
CA2433409A1 (en) 2002-08-15
DE60213365D1 (de) 2006-09-07
EP1359905B1 (de) 2006-07-26
JP2012131829A (ja) 2012-07-12
DE60213365T2 (de) 2007-08-09
US20040106582A1 (en) 2004-06-03
US20070265279A1 (en) 2007-11-15
BR0206917A (pt) 2004-02-03
WO2002062323A3 (en) 2003-03-20
ES2271229T3 (es) 2007-04-16
WO2002062323A2 (en) 2002-08-15
CN1253151C (zh) 2006-04-26
PT1359905E (pt) 2006-11-30
EP1359905A2 (de) 2003-11-12
CA2433409C (en) 2010-04-20
GB0103045D0 (en) 2001-03-21

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