AU2005303623A1 - Peptides derived from maurocalcine used as vectors for intracellular addressing of molecules of interest - Google Patents
Peptides derived from maurocalcine used as vectors for intracellular addressing of molecules of interest Download PDFInfo
- Publication number
- AU2005303623A1 AU2005303623A1 AU2005303623A AU2005303623A AU2005303623A1 AU 2005303623 A1 AU2005303623 A1 AU 2005303623A1 AU 2005303623 A AU2005303623 A AU 2005303623A AU 2005303623 A AU2005303623 A AU 2005303623A AU 2005303623 A1 AU2005303623 A1 AU 2005303623A1
- Authority
- AU
- Australia
- Prior art keywords
- peptide
- maurocalcine
- represent
- vector
- lysine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 229940048086 sodium pyrophosphate Drugs 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000002708 spider venom Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- HNKJADCVZUBCPG-UHFFFAOYSA-N thioanisole Chemical compound CSC1=CC=CC=C1 HNKJADCVZUBCPG-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 230000002463 transducing effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 125000000430 tryptophan group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 0.000 description 1
- 229910021642 ultra pure water Inorganic materials 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Insects & Arthropods (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0412045A FR2877946B1 (fr) | 2004-11-12 | 2004-11-12 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
| FR0412045 | 2004-11-12 | ||
| PCT/FR2005/002817 WO2006051224A1 (fr) | 2004-11-12 | 2005-11-14 | Peptides derives de la maurocalcine utilisables comme vecteurs pour l'adressage intracellulaire de molecules d'interet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2005303623A1 true AU2005303623A1 (en) | 2006-05-18 |
Family
ID=34953760
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2005303623A Abandoned AU2005303623A1 (en) | 2004-11-12 | 2005-11-14 | Peptides derived from maurocalcine used as vectors for intracellular addressing of molecules of interest |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8207293B2 (enExample) |
| EP (1) | EP1814905B1 (enExample) |
| JP (1) | JP5416901B2 (enExample) |
| CN (1) | CN101094863A (enExample) |
| AU (1) | AU2005303623A1 (enExample) |
| CA (1) | CA2586811A1 (enExample) |
| FR (1) | FR2877946B1 (enExample) |
| IL (1) | IL183022A0 (enExample) |
| WO (1) | WO2006051224A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2537858A1 (en) | 2011-06-20 | 2012-12-26 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Small efficient cell penetrating peptides derived from the scorpion toxin maurocalcine |
| WO2014141124A1 (en) | 2013-03-13 | 2014-09-18 | Institut National De La Sante Et De La Recherche Medicale | Erk-pathway activating compound for preventing or treating leptin resistance |
| CA2906663A1 (en) | 2013-03-15 | 2014-09-18 | Techulon Inc. | Antisense molecules for treatment of staphylococcus aureus infection |
| JP6600621B2 (ja) | 2013-03-15 | 2019-10-30 | テチュロン インコーポレイテッド | 黄色ブドウ球菌感染の治療のためのアンチセンス分子 |
| PL3007717T3 (pl) * | 2013-06-12 | 2018-12-31 | Pharis Biotec Gmbh | Peptydy o antagonistycznej aktywności w stosunku do naturalnego CXCR4 |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| CN105087492B (zh) * | 2015-07-16 | 2021-04-13 | 中国人民解放军军事医学科学院放射与辐射医学研究所 | 培养原代海马神经元的方法 |
| JP6966424B2 (ja) | 2015-09-09 | 2021-11-17 | フレッド ハッチンソン キャンサー リサーチ センター | 軟骨ホーミングペプチド |
| CA3005928A1 (en) * | 2015-12-11 | 2017-06-15 | Fred Hutchinson Cancer Research Center | Peptides for renal therapy |
| WO2018136614A1 (en) | 2017-01-18 | 2018-07-26 | Fred Hutchinson Cancer Research Center | Peptide compositions and methods of use thereof for disrupting tead interactions |
| CN110475565A (zh) | 2017-03-16 | 2019-11-19 | 光明之火生物科学公司 | 软骨归巢肽缀合物及其使用方法 |
| WO2018232122A1 (en) | 2017-06-15 | 2018-12-20 | Blaze Bioscience, Inc. | Renal-homing peptide conjugates and methods of use thereof |
| CA3086040A1 (en) | 2017-12-19 | 2019-06-27 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6051429A (en) * | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| FR2739621B1 (fr) | 1995-10-05 | 1997-12-05 | Centre Nat Rech Scient | Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives |
| EP1114060B1 (en) * | 1998-09-15 | 2003-06-11 | NIZO food research | Process for producing peptides from biological fluids and peptides obtainable by said process |
| GB0005124D0 (en) * | 2000-03-03 | 2000-04-26 | Cellpep Sa | Maurocalcin,analogues thereof and their therapeutical uses |
| DE60331437D1 (de) * | 2002-06-10 | 2010-04-08 | Amylin Pharmaceuticals Inc | Nachspaltige sulfurentschützung zur konvergenten proteinherstellung beim verfahren von chemischer ligation |
| SE0201863D0 (en) | 2002-06-18 | 2002-06-18 | Cepep Ab | Cell penetrating peptides |
-
2004
- 2004-11-12 FR FR0412045A patent/FR2877946B1/fr not_active Expired - Fee Related
-
2005
- 2005-11-14 WO PCT/FR2005/002817 patent/WO2006051224A1/fr not_active Ceased
- 2005-11-14 CA CA002586811A patent/CA2586811A1/fr not_active Abandoned
- 2005-11-14 JP JP2007540681A patent/JP5416901B2/ja not_active Expired - Fee Related
- 2005-11-14 CN CNA2005800457088A patent/CN101094863A/zh active Pending
- 2005-11-14 US US11/719,171 patent/US8207293B2/en not_active Expired - Fee Related
- 2005-11-14 EP EP05817457.4A patent/EP1814905B1/fr not_active Expired - Lifetime
- 2005-11-14 AU AU2005303623A patent/AU2005303623A1/en not_active Abandoned
-
2007
- 2007-05-06 IL IL183022A patent/IL183022A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2877946B1 (fr) | 2011-02-11 |
| FR2877946A1 (fr) | 2006-05-19 |
| EP1814905B1 (fr) | 2013-04-17 |
| JP2008519592A (ja) | 2008-06-12 |
| IL183022A0 (en) | 2007-09-20 |
| EP1814905A1 (fr) | 2007-08-08 |
| JP5416901B2 (ja) | 2014-02-12 |
| US8207293B2 (en) | 2012-06-26 |
| WO2006051224A1 (fr) | 2006-05-18 |
| CN101094863A (zh) | 2007-12-26 |
| CA2586811A1 (fr) | 2006-05-18 |
| US20090142266A1 (en) | 2009-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1 | Application lapsed section 142(2)(a) - no request for examination in relevant period |