JP2006514820A5 - - Google Patents
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- JP2006514820A5 JP2006514820A5 JP2003586178A JP2003586178A JP2006514820A5 JP 2006514820 A5 JP2006514820 A5 JP 2006514820A5 JP 2003586178 A JP2003586178 A JP 2003586178A JP 2003586178 A JP2003586178 A JP 2003586178A JP 2006514820 A5 JP2006514820 A5 JP 2006514820A5
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- JP
- Japan
- Prior art keywords
- peptide
- seq
- group
- nos
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 40
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 150000001413 amino acids Chemical class 0.000 claims 10
- 239000012634 fragment Substances 0.000 claims 6
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 125000003368 amide group Chemical group 0.000 claims 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 3
- 108091006116 chimeric peptides Proteins 0.000 claims 3
- 239000002245 particle Substances 0.000 claims 3
- 125000004122 cyclic group Chemical group 0.000 claims 2
- 230000008707 rearrangement Effects 0.000 claims 2
- 102000001490 Opioid Peptides Human genes 0.000 claims 1
- 108010093625 Opioid Peptides Proteins 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000003399 opiate peptide Substances 0.000 claims 1
- 108010091748 peptide A Proteins 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 230000005945 translocation Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/126,845 US20030181367A1 (en) | 1999-09-27 | 2002-04-19 | Conjugates of membrane translocating agents and pharmaceutically active agents |
| PCT/US2003/012543 WO2003089458A2 (en) | 2002-04-19 | 2003-04-21 | Conjugates of membrane translocating agents and pharmaceutically active agents |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010128982A Division JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006514820A JP2006514820A (ja) | 2006-05-18 |
| JP2006514820A5 true JP2006514820A5 (enExample) | 2006-07-06 |
Family
ID=29248426
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003586178A Withdrawn JP2006514820A (ja) | 2002-04-19 | 2003-04-21 | 膜転位剤および製薬学的有効成分の複合物 |
| JP2010128982A Expired - Fee Related JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010128982A Expired - Fee Related JP5211109B2 (ja) | 2002-04-19 | 2010-06-04 | 膜転位剤および製薬学的有効成分の複合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20030181367A1 (enExample) |
| EP (2) | EP1575987A4 (enExample) |
| JP (2) | JP2006514820A (enExample) |
| AU (1) | AU2003228658A1 (enExample) |
| CA (1) | CA2482719A1 (enExample) |
| WO (1) | WO2003089458A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3192786B2 (ja) | 1992-12-15 | 2001-07-30 | 積水化学工業株式会社 | 長尺体の分離供給装置 |
| US6521737B1 (en) * | 1995-11-10 | 2003-02-18 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| US7176185B2 (en) | 2003-11-25 | 2007-02-13 | Tsrl, Inc. | Short peptide carrier system for cellular delivery of agent |
| CA2939778C (en) | 2007-01-31 | 2019-01-29 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
| CA2682174C (en) | 2007-03-28 | 2021-04-06 | President And Fellows Of Harvard College | Stitched polypeptides |
| WO2009038770A2 (en) * | 2007-09-20 | 2009-03-26 | University Of Massachusetts Cvip | Detoxified recombinant botulinum neurotoxin |
| ES2334315B1 (es) * | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| KR20130099938A (ko) | 2010-08-13 | 2013-09-06 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
| CN104039342A (zh) | 2011-10-18 | 2014-09-10 | 爱勒让治疗公司 | 拟肽大环化合物 |
| HK1205454A1 (en) | 2012-02-15 | 2015-12-18 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| NZ627528A (en) | 2012-02-15 | 2016-05-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
| RU2657749C2 (ru) | 2012-09-21 | 2018-06-15 | Интенсити Терапьютикс, Инк | Способы лечения рака |
| US9788765B2 (en) | 2012-09-28 | 2017-10-17 | Dexcom, Inc. | Zwitterion surface modifications for continuous sensors |
| SG11201503052RA (en) | 2012-11-01 | 2015-05-28 | Aileron Therapeutics Inc | Disubstituted amino acids and methods of preparation and use thereof |
| US9737250B2 (en) | 2013-03-15 | 2017-08-22 | Dexcom, Inc. | Membrane for continuous analyte sensors |
| MX2017003797A (es) | 2014-09-24 | 2017-06-15 | Aileron Therapeutics Inc | Macrociclos peptidomimeticos y usos de los mismos. |
| WO2016154058A1 (en) | 2015-03-20 | 2016-09-29 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| CN108473538B (zh) * | 2015-10-28 | 2022-01-28 | 塔弗达治疗有限公司 | Sstr靶向缀合物及其颗粒和制剂 |
| US20170188922A1 (en) | 2015-12-30 | 2017-07-06 | Dexcom, Inc. | Biointerface layer for analyte sensors |
| WO2025096604A1 (en) * | 2023-10-30 | 2025-05-08 | Adjuvia Therapeutics | Pharmaceutical composition and method of treating disease using a molecular complex assembled on astaxanthin core |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847240A (en) | 1978-01-16 | 1989-07-11 | The Trustees Of Boston University | Method of effecting cellular uptake of molecules |
| US4244946A (en) * | 1979-06-11 | 1981-01-13 | The Salk Institute For Biological Studies | Water-soluble peptides affecting gonadal function |
| US4305872A (en) * | 1979-10-19 | 1981-12-15 | Kenneth Wingrove | Polypeptide derivatives |
| US4316891A (en) * | 1980-06-14 | 1982-02-23 | The Salk Institute For Biological Studies | Extended N-terminal somatostatin |
| US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US5449616A (en) * | 1990-05-23 | 1995-09-12 | University Of Iowa Research Foundation | Nucleic acid encoding dystrophin-associated protein |
| IE80466B1 (en) * | 1995-11-10 | 1998-07-29 | Elan Corp Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| US6361938B1 (en) * | 1996-11-08 | 2002-03-26 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| AU6972798A (en) * | 1997-04-18 | 1998-11-13 | University Of Medicine And Dentistry Of New Jersey | Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog |
| JP4129298B2 (ja) | 1997-05-15 | 2008-08-06 | サイトジェン コーポレーション | 胃腸管（ｇｉｔ）輸送受容体に結合するランダムペプチド、及び関連した方法 |
| US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| IE970794A1 (en) * | 1997-09-24 | 2000-08-23 | Elan Corp Plc | Composition and method for enhancing paracellular transport across cell layers |
| US6423334B1 (en) * | 1997-10-01 | 2002-07-23 | Elan Corporation, Plc | Composition and method for enhancing transport across gastrointestinal tract cell layers |
| US6248558B1 (en) * | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
| EP1086126A1 (en) | 1998-06-10 | 2001-03-28 | The Queen's University of Belfast | Cell-permeable peptide |
| US6348185B1 (en) | 1998-06-20 | 2002-02-19 | Washington University School Of Medicine | Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy |
| US6451601B1 (en) | 1999-04-12 | 2002-09-17 | Modex Therapeutiques, S.A. | Transiently immortalized cells for use in gene therapy |
| EP2269654A3 (en) | 1999-08-24 | 2011-04-13 | Cellgate Inc. | Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties |
| EP1230267B1 (en) * | 1999-09-27 | 2006-03-29 | Elan Corporation | Membrane translocating peptide drug delivery system |
| WO2002088318A2 (en) * | 2001-04-30 | 2002-11-07 | Targeted Genetics Corporation | Lipid-comprising drug delivery complexes and methods for their production |
| CN100443143C (zh) | 2002-12-11 | 2008-12-17 | 唐纳森公司 | Z形过滤介体的逆流清洗系统及其冲洗方法 |
| JP5008350B2 (ja) | 2006-07-05 | 2012-08-22 | 花王株式会社 | ガラス基板用の研磨液組成物 |
| US7981998B2 (en) | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
-
2002
- 2002-04-19 US US10/126,845 patent/US20030181367A1/en not_active Abandoned
-
2003
- 2003-04-21 WO PCT/US2003/012543 patent/WO2003089458A2/en not_active Ceased
- 2003-04-21 CA CA002482719A patent/CA2482719A1/en not_active Abandoned
- 2003-04-21 JP JP2003586178A patent/JP2006514820A/ja not_active Withdrawn
- 2003-04-21 EP EP03726420A patent/EP1575987A4/en not_active Withdrawn
- 2003-04-21 AU AU2003228658A patent/AU2003228658A1/en not_active Abandoned
- 2003-04-21 EP EP11182821A patent/EP2431055A1/en not_active Withdrawn
-
2004
- 2004-09-30 US US10/955,656 patent/US20050101762A1/en not_active Abandoned
-
2005
- 2005-12-16 US US11/303,372 patent/US7638599B2/en not_active Expired - Fee Related
-
2009
- 2009-12-23 US US12/645,922 patent/US8017727B2/en not_active Expired - Fee Related
-
2010
- 2010-06-04 JP JP2010128982A patent/JP5211109B2/ja not_active Expired - Fee Related
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