JP2008536483A5 - - Google Patents
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- Publication number
- JP2008536483A5 JP2008536483A5 JP2008500259A JP2008500259A JP2008536483A5 JP 2008536483 A5 JP2008536483 A5 JP 2008536483A5 JP 2008500259 A JP2008500259 A JP 2008500259A JP 2008500259 A JP2008500259 A JP 2008500259A JP 2008536483 A5 JP2008536483 A5 JP 2008536483A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- nucleic acid
- acid molecule
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 18
- 102000004196 processed proteins & peptides Human genes 0.000 claims 18
- 108090000765 processed proteins & peptides Proteins 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 150000001413 amino acids Chemical class 0.000 claims 5
- 102000019298 Lipocalin Human genes 0.000 claims 3
- 108050006654 Lipocalin Proteins 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 238000003745 diagnosis Methods 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 102220510486 Ras-related C3 botulinum toxin substrate 2_N92T_mutation Human genes 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002853 nucleic acid probe Substances 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0504767.5A GB0504767D0 (en) | 2005-03-08 | 2005-03-08 | Lipocalin protein |
| GB0504767.5 | 2005-03-08 | ||
| PCT/GB2006/000820 WO2006095164A1 (en) | 2005-03-08 | 2006-03-08 | Lipocalin protein |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008536483A JP2008536483A (ja) | 2008-09-11 |
| JP2008536483A5 true JP2008536483A5 (enExample) | 2009-04-30 |
| JP4933527B2 JP4933527B2 (ja) | 2012-05-16 |
Family
ID=34452020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008500259A Expired - Fee Related JP4933527B2 (ja) | 2005-03-08 | 2006-03-08 | リポカリンタンパク質 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20080254035A1 (enExample) |
| EP (1) | EP1869074A1 (enExample) |
| JP (1) | JP4933527B2 (enExample) |
| KR (1) | KR20070118614A (enExample) |
| CN (1) | CN101189257A (enExample) |
| AU (1) | AU2006221859B2 (enExample) |
| BR (1) | BRPI0609020A2 (enExample) |
| CA (1) | CA2599540A1 (enExample) |
| EA (1) | EA011816B1 (enExample) |
| GB (1) | GB0504767D0 (enExample) |
| IL (1) | IL185547A0 (enExample) |
| MX (1) | MX2007010809A (enExample) |
| NO (1) | NO20075068L (enExample) |
| UA (1) | UA94221C2 (enExample) |
| WO (1) | WO2006095164A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2360519T3 (es) | 2005-04-22 | 2011-06-06 | University Of Washington | Conjugado de cianina-clorotoxina y procedimiento para la visualización intraquirúrgica del cáncer. |
| WO2009023184A2 (en) | 2007-08-10 | 2009-02-19 | Protelix, Inc. | Universal fibronectin type iii binding-domain libraries |
| US8680019B2 (en) * | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
| US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
| BRPI0912683A2 (pt) | 2008-05-15 | 2016-01-26 | Transmolecular Inc | tratamento de tumores metastáticos |
| KR20170091801A (ko) | 2008-10-02 | 2017-08-09 | 압테보 리서치 앤드 디벨롭먼트 엘엘씨 | Ｃｄ86 길항제 다중-표적 결합 단백질 |
| US20130052195A1 (en) | 2009-12-23 | 2013-02-28 | Emergent Product Development Seattle,LLC | Compositions Comprising TNF-alpha and IL-6 Antagonists and Methods of Use Thereof |
| US20130089554A1 (en) | 2009-12-29 | 2013-04-11 | Emergent Product Development Seattle, Llc | RON Binding Constructs and Methods of Use Thereof |
| AU2011213678B2 (en) | 2010-02-04 | 2015-01-29 | Eisai Inc. | Chlorotoxin polypeptides and conjugates and uses thereof |
| WO2011142858A2 (en) | 2010-05-11 | 2011-11-17 | Fred Hutchinson Cancer Research Center | Chlorotoxin variants, conjugates, and methods for their use |
| DK2606061T3 (da) * | 2010-08-16 | 2017-11-06 | Pieris Pharmaceuticals Gmbh | Bindingsproteiner til hepcidin |
| US8846042B2 (en) | 2011-05-16 | 2014-09-30 | Fabion Pharmaceuticals, Inc. | Multi-specific FAB fusion proteins and methods of use |
| CN104487587A (zh) | 2012-04-20 | 2015-04-01 | 新兴产品开发西雅图有限公司 | Cd3结合多肽 |
| CN105189540A (zh) * | 2012-12-10 | 2015-12-23 | 弗莱德哈钦森癌症研究中心 | 含脂质运载蛋白融合伴侣 |
| JP6392315B2 (ja) | 2013-03-14 | 2018-09-19 | イミュソフト コーポレーション | インビトロでのメモリーｂ細胞分化方法およびｖｓｖ−ｇ偽型ウイルスベクターを用いる形質導入方法 |
| AU2014296626B2 (en) | 2013-07-29 | 2019-03-07 | Regeneron Pharmaceuticals, Inc. | Multipartite signaling proteins and uses thereof |
| US11559580B1 (en) | 2013-09-17 | 2023-01-24 | Blaze Bioscience, Inc. | Tissue-homing peptide conjugates and methods of use thereof |
| KR20160079854A (ko) | 2013-10-31 | 2016-07-06 | 프레드 헛친슨 켄서 리서치 센터 | 변형된 조혈 줄기/선조 및 비-t 효과기 세포 및 이의 용도 |
| WO2015095553A1 (en) * | 2013-12-20 | 2015-06-25 | Nephrogenesis, Llc | Methods and apparatus for kidney dialysis |
| RS61223B1 (sr) | 2013-12-20 | 2021-01-29 | Hutchinson Fred Cancer Res | Označeni himerni efektorski molekuli i njihovi receptori |
| JP5866053B1 (ja) * | 2014-12-15 | 2016-02-17 | 株式会社ファンケル | 皮膚粘弾性のマーカー及びその利用 |
| DK3234107T3 (da) | 2014-12-19 | 2022-10-17 | Immusoft Corp | B-celler til in vivo-levering af terapeutiske midler |
| CA2978186A1 (en) | 2015-03-05 | 2016-09-09 | Fred Hutchinson Cancer Research Center | Immunomodulatory fusion proteins and uses thereof |
| US11827904B2 (en) | 2015-04-29 | 2023-11-28 | Fred Hutchinson Cancer Center | Modified stem cells and uses thereof |
| JP6985934B2 (ja) | 2015-04-29 | 2021-12-22 | フレッド ハッチンソン キャンサー リサーチ センター | 操作された造血幹細胞／前駆細胞及び非ｔエフェクター細胞、ならびにその使用 |
| HK1251480A1 (zh) | 2015-09-21 | 2019-02-01 | Aptevo Research And Development Llc | Cd3结合多肽 |
| EP3430058A4 (en) | 2016-03-15 | 2019-10-23 | Generon (Shanghai) Corporation Ltd. | MULTISPECIFIC FAB FUSION PROTEINS AND USES THEREOF |
| CR20180503A (es) | 2016-04-14 | 2018-12-21 | Hutchinson Fred Cancer Res | Composiciones y métodos para programar células terapéuticas utilizando nanoportadores de ácidos nucleicos dirigidos |
| WO2017181149A1 (en) | 2016-04-15 | 2017-10-19 | Blaze Bioscience, Inc. | Methods of treating breast cancer |
| CN117357638A (zh) | 2017-02-17 | 2024-01-09 | 弗雷德哈钦森癌症中心 | 用于治疗bcma相关癌症和自身免疫性失调的联合疗法 |
| JP2020511136A (ja) | 2017-03-17 | 2020-04-16 | フレッド ハッチンソン キャンサー リサーチ センター | 免疫調節性融合タンパク質およびその使用 |
| AU2018385699B2 (en) | 2017-12-14 | 2024-08-15 | Regeneron Pharmaceuticals, Inc. | Daric interleukin receptors |
| EP3847196A4 (en) | 2018-09-07 | 2023-01-04 | ITabMed (HK) Limited | BISPECIFIC ANTIGEN BINDING PROTEINS AND USES THEREOF |
| EP4268831A3 (en) | 2018-09-12 | 2024-05-22 | Fred Hutchinson Cancer Center | Reducing cd33 expression to selectively protect therapeutic cells |
| US12291560B2 (en) | 2018-12-14 | 2025-05-06 | Regeneron Pharmaceuticals, Inc. | Dimerizing agent regulated immunoreceptor complexes |
| BR112021020999A2 (pt) | 2019-05-04 | 2021-12-14 | Inhibrx Inc | Polipeptídeos de ligação à clec12a e usos dos mesmos |
| CA3148027A1 (en) | 2019-05-08 | 2020-11-12 | 2Seventy Bio, Inc. | Cll-1 targeted immunotherapies |
| BR112021026832A2 (pt) | 2019-07-02 | 2022-05-10 | Hutchinson Fred Cancer Res | Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada |
| IL297412A (en) | 2020-05-04 | 2022-12-01 | Immunorizon Ltd | Precursor tri-specific antibody constructs and methods of use thereof |
| CN111979249B (zh) * | 2020-07-28 | 2021-12-10 | 复旦大学附属眼耳鼻喉科医院 | 一种特异性结合脂质运载蛋白-1的核酸适配体及其应用 |
| WO2023215725A1 (en) | 2022-05-02 | 2023-11-09 | Fred Hutchinson Cancer Center | Compositions and methods for cellular immunotherapy |
| WO2025101820A1 (en) | 2023-11-08 | 2025-05-15 | Fred Hutchinson Cancer Center | Compositions and methods for cellular immunotherapy |
| WO2025245169A1 (en) | 2024-05-21 | 2025-11-27 | Fred Hutchinson Cancer Center | Immunotherapy cells equipped with a collagen-targeting payload |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364780A (en) * | 1989-03-17 | 1994-11-15 | E. I. Du Pont De Nemours And Company | External regulation of gene expression by inducible promoters |
| US5252479A (en) * | 1991-11-08 | 1993-10-12 | Research Corporation Technologies, Inc. | Safe vector for gene therapy |
| US5362865A (en) * | 1993-09-02 | 1994-11-08 | Monsanto Company | Enhanced expression in plants using non-translated leader sequences |
| US5693506A (en) * | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US6818418B1 (en) * | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| WO2002018571A2 (en) * | 2000-08-31 | 2002-03-07 | Zymogenetics, Inc. | Human phermone polypeptides |
-
2005
- 2005-03-08 GB GBGB0504767.5A patent/GB0504767D0/en not_active Ceased
-
2006
- 2006-03-08 CN CNA2006800153195A patent/CN101189257A/zh active Pending
- 2006-03-08 JP JP2008500259A patent/JP4933527B2/ja not_active Expired - Fee Related
- 2006-03-08 EA EA200701918A patent/EA011816B1/ru not_active IP Right Cessation
- 2006-03-08 WO PCT/GB2006/000820 patent/WO2006095164A1/en not_active Ceased
- 2006-03-08 CA CA002599540A patent/CA2599540A1/en not_active Abandoned
- 2006-03-08 BR BRPI0609020A patent/BRPI0609020A2/pt not_active IP Right Cessation
- 2006-03-08 EP EP06710035A patent/EP1869074A1/en not_active Withdrawn
- 2006-03-08 AU AU2006221859A patent/AU2006221859B2/en not_active Ceased
- 2006-03-08 KR KR1020077022395A patent/KR20070118614A/ko not_active Ceased
- 2006-03-08 MX MX2007010809A patent/MX2007010809A/es active IP Right Grant
- 2006-03-08 US US11/817,296 patent/US20080254035A1/en not_active Abandoned
- 2006-08-03 UA UAA200711037A patent/UA94221C2/ru unknown
-
2007
- 2007-08-27 IL IL185547A patent/IL185547A0/en unknown
- 2007-10-08 NO NO20075068A patent/NO20075068L/no not_active Application Discontinuation
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