JP2012531208A5 - - Google Patents

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Publication number
JP2012531208A5
JP2012531208A5 JP2012517785A JP2012517785A JP2012531208A5 JP 2012531208 A5 JP2012531208 A5 JP 2012531208A5 JP 2012517785 A JP2012517785 A JP 2012517785A JP 2012517785 A JP2012517785 A JP 2012517785A JP 2012531208 A5 JP2012531208 A5 JP 2012531208A5
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JP
Japan
Prior art keywords
polypeptide
sequence
nucleic acid
acid molecule
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2012517785A
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English (en)
Japanese (ja)
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JP2012531208A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/040052 external-priority patent/WO2010151808A1/en
Publication of JP2012531208A publication Critical patent/JP2012531208A/ja
Publication of JP2012531208A5 publication Critical patent/JP2012531208A5/ja
Withdrawn legal-status Critical Current

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JP2012517785A 2009-06-26 2010-06-25 代替軽鎖の発現 Withdrawn JP2012531208A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22087809P 2009-06-26 2009-06-26
US61/220,878 2009-06-26
PCT/US2010/040052 WO2010151808A1 (en) 2009-06-26 2010-06-25 Expression of surrogate light chains

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015256676A Division JP2016105714A (ja) 2009-06-26 2015-12-28 代替軽鎖の発現

Publications (2)

Publication Number Publication Date
JP2012531208A JP2012531208A (ja) 2012-12-10
JP2012531208A5 true JP2012531208A5 (enExample) 2013-08-08

Family

ID=42563044

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012517785A Withdrawn JP2012531208A (ja) 2009-06-26 2010-06-25 代替軽鎖の発現
JP2015256676A Pending JP2016105714A (ja) 2009-06-26 2015-12-28 代替軽鎖の発現

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015256676A Pending JP2016105714A (ja) 2009-06-26 2015-12-28 代替軽鎖の発現

Country Status (12)

Country Link
US (1) US8969082B2 (enExample)
EP (2) EP3205723A1 (enExample)
JP (2) JP2012531208A (enExample)
KR (2) KR101829073B1 (enExample)
CN (1) CN102498210B (enExample)
AU (1) AU2010265949B2 (enExample)
BR (1) BRPI1015916A2 (enExample)
CA (1) CA2764729C (enExample)
IL (1) IL216796A (enExample)
MX (1) MX2012000129A (enExample)
TW (1) TWI560271B (enExample)
WO (1) WO2010151808A1 (enExample)

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US10968276B2 (en) 2013-03-12 2021-04-06 Xencor, Inc. Optimized anti-CD3 variable regions
CA2897987A1 (en) 2013-01-15 2014-07-24 Xencor, Inc. Rapid clearance of antigen complexes using novel antibodies
US10106624B2 (en) 2013-03-15 2018-10-23 Xencor, Inc. Heterodimeric proteins
EP2970486B1 (en) 2013-03-15 2018-05-16 Xencor, Inc. Modulation of t cells with bispecific antibodies and fc fusions
US10858417B2 (en) 2013-03-15 2020-12-08 Xencor, Inc. Heterodimeric proteins
US10519242B2 (en) 2013-03-15 2019-12-31 Xencor, Inc. Targeting regulatory T cells with heterodimeric proteins
US9788534B2 (en) 2013-03-18 2017-10-17 Kymab Limited Animal models and therapeutic molecules
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US20150033372A1 (en) * 2013-05-01 2015-01-29 Kymab Limited Human VpreB & Chimaeric Surrogate Light Chains in Transgenic Non-Human Vertebrates
US11707056B2 (en) 2013-05-02 2023-07-25 Kymab Limited Animals, repertoires and methods
US9783593B2 (en) 2013-05-02 2017-10-10 Kymab Limited Antibodies, variable domains and chains tailored for human use
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JP6775422B2 (ja) 2014-03-28 2020-10-28 ゼンコー・インコーポレイテッドXencor、 Inc. Cd38及びcd3に結合する二重特異性抗体
SG11201704283PA (en) 2014-11-26 2017-06-29 Xencor Inc Heterodimeric antibodies that bind cd3 and tumor antigens
US10259887B2 (en) 2014-11-26 2019-04-16 Xencor, Inc. Heterodimeric antibodies that bind CD3 and tumor antigens
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US11384350B2 (en) 2014-12-15 2022-07-12 The Regents Of The University Of California Cytotoxic molecules responsive to intracellular ligands for selective T cell mediated killing
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