|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
DE3374837D1
(en)
|
1982-02-17 |
1988-01-21 |
Ciba Geigy Ag |
Lipids in the aqueous phase
|
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
|
EP0143949B1
(en)
|
1983-11-01 |
1988-10-12 |
TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION |
Pharmaceutical composition containing urokinase
|
|
US4965195A
(en)
|
1987-10-26 |
1990-10-23 |
Immunex Corp. |
Interleukin-7
|
|
US4968607A
(en)
|
1987-11-25 |
1990-11-06 |
Immunex Corporation |
Interleukin-1 receptors
|
|
WO1990005183A1
(en)
|
1988-10-31 |
1990-05-17 |
Immunex Corporation |
Interleukin-4 receptors
|
|
US5714465A
(en)
|
1989-05-19 |
1998-02-03 |
Amgen Inc. |
Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor
|
|
US7144731B2
(en)
|
1989-10-16 |
2006-12-05 |
Amgen Inc. |
SCF antibody compositions and methods of using the same
|
|
WO1991018982A1
(en)
|
1990-06-05 |
1991-12-12 |
Immunex Corporation |
Type ii interleukin-1 receptors
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
JPH05244982A
(ja)
|
1991-12-06 |
1993-09-24 |
Sumitomo Chem Co Ltd |
擬人化ｂ−ｂ１０
|
|
US6239328B1
(en)
|
1992-10-05 |
2001-05-29 |
North Carolina State University |
Method for reducing expression variability of transgenes in plant cells
|
|
US5574138A
(en)
|
1993-03-08 |
1996-11-12 |
Immunex Corporation |
Epithelium-derived T-cell factor
|
|
US7138500B1
(en)
|
1993-05-07 |
2006-11-21 |
Immunex Corporation |
Antibodies to human 4-1BB
|
|
US7211259B1
(en)
|
1993-05-07 |
2007-05-01 |
Immunex Corporation |
4-1BB polypeptides and DNA encoding 4-1BB polypeptides
|
|
US6630143B1
(en)
|
1993-05-24 |
2003-10-07 |
Immunex Corporation |
Antibodies against flt3 ligand
|
|
US7045128B2
(en)
|
1993-05-24 |
2006-05-16 |
Immunex Corporation |
Antibodies against flt3-ligand
|
|
US6303769B1
(en)
|
1994-07-08 |
2001-10-16 |
Immunex Corporation |
Lerk-5 dna
|
|
US5885574A
(en)
|
1994-07-26 |
1999-03-23 |
Amgen Inc. |
Antibodies which activate an erythropoietin receptor
|
|
US5919905A
(en)
|
1994-10-05 |
1999-07-06 |
Immunex Corporation |
Cytokine designated LERK-6
|
|
US6406901B1
(en)
|
1995-06-08 |
2002-06-18 |
Immunex Corporation |
TNF-a converting enzyme
|
|
EP0938499A1
(en)
|
1996-07-19 |
1999-09-01 |
Amgen Inc. |
Analogs of cationic proteins
|
|
US6037525A
(en)
|
1996-08-01 |
2000-03-14 |
North Carolina State University |
Method for reducing expression variability of transgenes in plant cells
|
|
WO1998028424A2
(en)
|
1996-12-23 |
1998-07-02 |
Immunex Corporation |
Receptor activator of nf-kappa b, receptor is member of tnf receptor superfamily
|
|
US5741772A
(en)
|
1997-02-03 |
1998-04-21 |
Amgen Inc. |
Neurotrophic factor NNT-1
|
|
BR9808545A
(pt)
|
1997-04-16 |
2000-05-23 |
Amgen Inc |
ácido nucleico isolado, vetor de expressão, célula hospedeira, processos para produzir uma proteìna de ligação da osteoprotegerina, para detectar a presença de uma proteìna de ligação à osteoprotegerina em uma amostra biológica, para avaliar a capacidade de um composto candidato de ligar-se a uma proteìna de ligação da osteoprotegerina e de um composto de teste para aumentar ou reduzir a ligação da proteìna de ligação da osteoprotegerina a odar, para regular a expressão de uma proteìna de ligação da osteoprotegerina em um animal e para prevenir ou tratar de doença óssea em um mamìfero, polipeptìdeo, protéina de ligação da osteroprotegerina purificada e isolada, ou seu fragmento, análogo ou derivado, e, anticorpo ou seu fragmento
|
|
US6316408B1
(en)
|
1997-04-16 |
2001-11-13 |
Amgen Inc. |
Methods of use for osetoprotegerin binding protein receptors
|
|
US20020173629A1
(en)
|
1997-05-05 |
2002-11-21 |
Aya Jakobovits |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US6245974B1
(en)
|
1997-08-06 |
2001-06-12 |
North Carolina State University |
Matrix attachment regions
|
|
AU742757C
(en)
|
1997-12-17 |
2007-05-17 |
Immunex Corporation |
Cell surface glycoproteins associated with human B cell lymphomas - ULBP, DNA and polypeptides
|
|
JP2001526892A
(ja)
|
1997-12-23 |
2001-12-25 |
イミュネックス・コーポレーション |
Ｓｉｇｉｒｒｄｎａおよびポリペプチド
|
|
WO1999033878A1
(en)
|
1997-12-25 |
1999-07-08 |
Japan Tobacco Inc. |
Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
|
|
NZ505499A
(en)
|
1998-01-23 |
2002-07-26 |
Immunex Corp |
Accessory protein-like DNA and polypeptides
|
|
US6177612B1
(en)
|
1998-07-31 |
2001-01-23 |
Her Majesty The Queen In Right Of Canada, As Represented By The Department Of Agriculture And Agri-Food Canada |
Matrix attachment regions
|
|
EP1108042B1
(en)
|
1998-08-07 |
2008-11-26 |
Immunex Corporation |
Molecules designated b7l-1
|
|
JP4426724B2
(ja)
|
1998-08-07 |
2010-03-03 |
イミュネックス・コーポレーション |
Ｌｄｃａｍと称される分子
|
|
US6210924B1
(en)
|
1998-08-11 |
2001-04-03 |
Amgen Inc. |
Overexpressing cyclin D 1 in a eukaryotic cell line
|
|
WO2000018938A1
(en)
|
1998-09-29 |
2000-04-06 |
Pioneer Hi-Bred International, Inc. |
Mar/sar elements flanking rsyn7-driven construct
|
|
ES2288036T5
(es)
|
1998-11-13 |
2017-07-06 |
Immunex Corporation |
ADN de TSLP humano y polipéptidos
|
|
US7109003B2
(en)
|
1998-12-23 |
2006-09-19 |
Abgenix, Inc. |
Methods for expressing and recovering human monoclonal antibodies to CTLA-4
|
|
EE05627B1
(et)
|
1998-12-23 |
2013-02-15 |
Pfizer Inc. |
CTLA-4 vastased inimese monoklonaalsed antikehad
|
|
US6737056B1
(en)
*
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US7435796B1
(en)
|
1999-02-03 |
2008-10-14 |
Amgen Inc. |
Antibodies which bind B7RP1
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
JP2001206899A
(ja)
|
1999-11-18 |
2001-07-31 |
Japan Tobacco Inc |
ＴＧＦ−βＩＩ型受容体に対するヒトモノクローナル抗体及びその医薬用途
|
|
US20030103978A1
(en)
|
2000-02-23 |
2003-06-05 |
Amgen Inc. |
Selective binding agents of osteoprotegerin binding protein
|
|
EP2990420B1
(en)
|
2000-05-26 |
2016-12-21 |
Immunex Corporation |
Use of interleukin-4 receptor antibodies and compositions thereof
|
|
KR100408844B1
(ko)
|
2000-07-29 |
2003-12-06 |
한국산업기술평가원 |
동물세포 발현벡터
|
|
CA2421588C
(en)
|
2000-09-05 |
2010-01-26 |
Amgen Inc. |
Tnf receptor-like molecules and uses thereof
|
|
US7259010B2
(en)
|
2000-12-15 |
2007-08-21 |
Pangen Biotech Inc. |
Expression vector for animal cell containing nuclear matrix attachment region of interferon beta
|
|
AR032028A1
(es)
|
2001-01-05 |
2003-10-22 |
Pfizer |
Anticuerpos contra el receptor del factor de crecimiento similar a insulina
|
|
ATE437233T1
(de)
|
2001-01-26 |
2009-08-15 |
Selexis Sa |
Matrix-anheftungsregionen und verfahren zu deren verwendung
|
|
AU2002356511A1
(en)
|
2001-07-30 |
2003-04-01 |
Immunex Corporation |
T. reesei phytase enyzmes, polynucleides encoding the enzymes, vectors and host cells thereof, and methods of using
|
|
US7084257B2
(en)
|
2001-10-05 |
2006-08-01 |
Amgen Inc. |
Fully human antibody Fab fragments with human interferon-gamma neutralizing activity
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7658924B2
(en)
|
2001-10-11 |
2010-02-09 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
ES2606537T3
(es)
|
2001-10-23 |
2017-03-24 |
Psma Development Company L.L.C. |
Anticuerpos contra PSMA
|
|
AR039067A1
(es)
|
2001-11-09 |
2005-02-09 |
Pfizer Prod Inc |
Anticuerpos para cd40
|
|
WO2003048327A2
(en)
|
2001-12-03 |
2003-06-12 |
Abgenix, Inc. |
Anti-cd45rb antibodies for use in treating autoimmune disease and transplant rejection
|
|
AU2002351208A1
(en)
|
2001-12-03 |
2003-06-17 |
Abgenix, Inc. |
Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
|
|
JP2005516965A
(ja)
|
2001-12-28 |
2005-06-09 |
アブジェニックス・インコーポレーテッド |
抗ｍｕｃ１８抗体を使用する方法
|
|
EP1470146B8
(en)
|
2001-12-28 |
2007-09-12 |
Amgen Fremont Inc. |
Antibodies against the muc18 antigen
|
|
JP2005514409A
(ja)
|
2001-12-28 |
2005-05-19 |
アブジェニックス・インコーポレーテッド |
Ｍｕｃ１８抗原に対する抗体の使用
|
|
US7135174B2
(en)
|
2002-01-07 |
2006-11-14 |
Amgen Fremont, Inc. |
Antibodies directed to PDGFD and uses thereof
|
|
US8188231B2
(en)
*
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
MXPA04009418A
(es)
|
2002-03-29 |
2005-06-08 |
Schering Corp |
Anticuerpos monoclonales humanos par interleucina-5, y metodos y composiciones que comprenden los mismos.
|
|
US7718776B2
(en)
|
2002-04-05 |
2010-05-18 |
Amgen Inc. |
Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
|
|
EP1542724A4
(en)
|
2002-08-19 |
2005-10-19 |
Abgenix Inc |
ANTIBODIES AGAINST THE MONOCYTE 1 CHIMIOATTRACTIVE PROTEIN (MCP-1) AND USES THEREOF
|
|
PL377091A1
(pl)
|
2002-09-06 |
2006-01-23 |
Amgen, Inc. |
Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych
|
|
CA2499816C
(en)
*
|
2002-09-27 |
2013-07-30 |
Xencor, Inc. |
Optimized fc variants and methods for their generation
|
|
WO2004034988A2
(en)
|
2002-10-16 |
2004-04-29 |
Amgen Inc. |
Human anti-ifn-ϝ neutralizing antibodies as selective ifn-ϝ pathway inhibitors
|
|
JP4754219B2
(ja)
|
2002-12-02 |
2011-08-24 |
アムジエン・フレモント・インコーポレイテツド |
腫瘍壊死因子を対象とする抗体、およびそれらの使用
|
|
US20090010920A1
(en)
*
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
KR101531400B1
(ko)
|
2003-06-27 |
2015-06-26 |
암젠 프레몬트 인코포레이티드 |
상피 성장 인자 수용체의 결실 돌연변이체 지향 항체 및 그용도
|
|
EA013614B1
(ru)
|
2003-07-15 |
2010-06-30 |
Амджен Инк. |
Изолированное антитело к фактору роста нервов (ngf) и способы его применения
|
|
JP2007500132A
(ja)
|
2003-07-25 |
2007-01-11 |
アムジェン インコーポレイテッド |
Ｌｄｃａｍのアンタゴニストおよびアゴニスト、並びにその使用法
|
|
HN2004000285A
(es)
|
2003-08-04 |
2006-04-27 |
Pfizer Prod Inc |
ANTICUERPOS DIRIGIDOS A c-MET
|
|
JP2007521232A
(ja)
|
2003-08-08 |
2007-08-02 |
アブジェニックス・インコーポレーテッド |
副甲状腺ホルモン（ｐｔｈ）に対する抗体およびその使用
|
|
US7318925B2
(en)
|
2003-08-08 |
2008-01-15 |
Amgen Fremont, Inc. |
Methods of use for antibodies against parathyroid hormone
|
|
AR045563A1
(es)
|
2003-09-10 |
2005-11-02 |
Warner Lambert Co |
Anticuerpos dirigidos a m-csf
|
|
WO2005047331A2
(en)
|
2003-11-07 |
2005-05-26 |
Immunex Corporation |
Antibodies that bind interleukin-4 receptor
|
|
CN1938428A
(zh)
|
2003-11-12 |
2007-03-28 |
先灵公司 |
多基因表达的质粒系统
|
|
WO2005058961A2
(en)
|
2003-12-12 |
2005-06-30 |
Amgen Inc. |
Antibodies specific for human galanin, and uses thereof
|
|
CN1956738B
(zh)
|
2004-01-09 |
2013-05-29 |
辉瑞大药厂 |
MAdCAM抗体
|
|
RS20060581A
(sr)
|
2004-04-23 |
2008-11-28 |
Amgen Inc., |
Antitela na domene cd148 koji inhibiraju angiogenezu
|
|
AU2005250341A1
(en)
|
2004-04-23 |
2005-12-15 |
Amgen Inc. |
Antibodies to angiogenesis inhibiting domains of CD148
|
|
BRPI0510674A
(pt)
*
|
2004-07-15 |
2007-12-26 |
Xencor Inc |
variantes fc otimizadas
|
|
ES2414460T3
(es)
|
2004-08-04 |
2013-07-19 |
Amgen Inc. |
Anticuerpos para Dkk-1
|
|
US7423128B2
(en)
|
2004-11-03 |
2008-09-09 |
Amgen Fremont Inc. |
Anti-properdin antibodies, and methods for making and using same
|
|
MX2007005866A
(es)
|
2004-11-17 |
2007-11-12 |
Amgen Inc |
Anticuerpos monoclonales totalmente humanos para il-13.
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
EP1841455A1
(en)
|
2005-01-24 |
2007-10-10 |
Amgen Inc. |
Humanized anti-amyloid antibody
|
|
EP1851245B1
(en)
|
2005-01-26 |
2012-10-10 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
EP3058955B1
(en)
|
2005-03-24 |
2019-05-29 |
Millennium Pharmaceuticals, Inc. |
Antibodies that bind ov064 and methods of use therefor
|
|
EA201100642A1
(ru)
|
2005-04-25 |
2011-12-30 |
Пфайзер Инк. |
Антитела к миостатину
|
|
US7592429B2
(en)
|
2005-05-03 |
2009-09-22 |
Ucb Sa |
Sclerostin-binding antibody
|
|
MX2007013924A
(es)
*
|
2005-05-09 |
2008-01-28 |
Glycart Biotechnology Ag |
Moleculas que unen antigeno que tienen regiones fc modificadas y union alterada a receptores fc.
|
|
EP1909831A4
(en)
|
2005-06-14 |
2013-02-20 |
Amgen Inc |
SELF-BUFFING PROTEIN FORMULATIONS
|
|
CA2854576A1
(en)
|
2005-07-18 |
2007-01-25 |
Haichun Huang |
Human anti-b7rp1 neutralizing antibodies
|
|
PE20071101A1
(es)
|
2005-08-31 |
2007-12-21 |
Amgen Inc |
Polipeptidos y anticuerpos
|
|
DK1933871T3
(da)
|
2005-09-07 |
2013-07-08 |
Amgen Fremont Inc |
Humane monoklonale antistoffer mod activin-receptor-lignende kinase-1
|
|
US7939637B2
(en)
|
2005-12-13 |
2011-05-10 |
Medimmune Limited |
Insulin-like growth factor antibodies and uses thereof
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
US7888482B2
(en)
|
2006-02-10 |
2011-02-15 |
Amgen Inc. |
Antibodies that bind PAR-2
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
EP2035454A2
(en)
|
2006-05-19 |
2009-03-18 |
Amgen, Inc. |
Antibodies to sars coronavirus
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
CL2007002668A1
(es)
|
2006-09-20 |
2008-05-09 |
Amgen Inc |
Proteina de union a antigeno que se une al receptor de glucagon humano; acido nucleico que la codifica; metodo de produccion; composicion farmaceutica que la comprende; y su uso para tratar o prevenir la diabetes tipo 2.
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
US7867494B2
(en)
|
2007-04-02 |
2011-01-11 |
Amgen Fremont Inc. |
Anti-IgE antibodies
|
|
JP2010525820A
(ja)
*
|
2007-04-30 |
2010-07-29 |
セントコア・オーソ・バイオテツク・インコーポレーテツド |
増強されたエフェクター機能を有する、抗組織因子抗体及び組成物
|
|
CL2008001887A1
(es)
|
2007-06-29 |
2008-10-03 |
Amgen Inc |
Proteinas de union a antigeno que se unen al receptor activado por proteasas 2 (par-2); acido nucleico que las codifica; vector y celula huesped; metodo de produccion; y composicion que las comprende.
|
|
KR101559596B1
(ko)
*
|
2007-07-17 |
2015-10-12 |
메르크 파텐트 게엠베하 |
조작 항-알파 ｖ-인테그린 잡종 항체
|
|
CL2008002153A1
(es)
|
2007-07-24 |
2009-06-05 |
Amgen Inc |
Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
|
|
TWI595005B
(zh)
|
2007-08-21 |
2017-08-11 |
安健股份有限公司 |
人類ｃ－ｆｍｓ抗原結合蛋白質
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
|
CA2709354C
(en)
|
2007-12-21 |
2014-06-17 |
Amgen Inc. |
Anti-amyloid antibodies and uses thereof
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
EP2816059A1
(en)
|
2008-05-01 |
2014-12-24 |
Amgen, Inc |
Anti-hepcidin antibodies and methods of use
|
|
KR101391472B1
(ko)
|
2009-03-20 |
2014-05-07 |
암젠 인크 |
알파-4-베타-7 이종이량체 특이적 길항제 항체
|
|
EP2233500A1
(en)
|
2009-03-20 |
2010-09-29 |
LFB Biotechnologies |
Optimized Fc variants
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
RU2012145183A
(ru)
|
2010-03-29 |
2014-05-10 |
Займворкс, Инк. |
Антитела с повышенной или пониженной эффекторной функцией
|
|
US8722044B2
(en)
|
2011-03-15 |
2014-05-13 |
Janssen Biotech, Inc. |
Human tissue factor antibody and uses thereof
|
|
TW201326209A
(zh)
*
|
2011-09-30 |
2013-07-01 |
Chugai Pharmaceutical Co Ltd |
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|
|
US9401875B2
(en)
|
2012-06-01 |
2016-07-26 |
Nippon Telegraph And Telephone Corporation |
Packet transfer processing method and packet transfer processing device
|
|
US9300829B2
(en)
|
2014-04-04 |
2016-03-29 |
Canon Kabushiki Kaisha |
Image reading apparatus and correction method thereof
|