JP2017517257A5 - - Google Patents

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Publication number
JP2017517257A5
JP2017517257A5 JP2016568644A JP2016568644A JP2017517257A5 JP 2017517257 A5 JP2017517257 A5 JP 2017517257A5 JP 2016568644 A JP2016568644 A JP 2016568644A JP 2016568644 A JP2016568644 A JP 2016568644A JP 2017517257 A5 JP2017517257 A5 JP 2017517257A5
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JP
Japan
Prior art keywords
protein
dna sequence
negative strain
effector protein
proteins
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JP2016568644A
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English (en)
Japanese (ja)
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JP6797025B2 (ja
JP2017517257A (ja
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Priority claimed from PCT/EP2015/061086 external-priority patent/WO2015177197A1/en
Publication of JP2017517257A publication Critical patent/JP2017517257A/ja
Publication of JP2017517257A5 publication Critical patent/JP2017517257A5/ja
Application granted granted Critical
Publication of JP6797025B2 publication Critical patent/JP6797025B2/ja
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JP2016568644A 2014-05-21 2015-05-20 細菌に基づくタンパク質送達 Active JP6797025B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14169335.8 2014-05-21
EP14169335 2014-05-21
PCT/EP2015/061086 WO2015177197A1 (en) 2014-05-21 2015-05-20 Bacteria-based protein delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020121375A Division JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達

Publications (3)

Publication Number Publication Date
JP2017517257A JP2017517257A (ja) 2017-06-29
JP2017517257A5 true JP2017517257A5 (enExample) 2018-06-28
JP6797025B2 JP6797025B2 (ja) 2020-12-09

Family

ID=50771120

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016568644A Active JP6797025B2 (ja) 2014-05-21 2015-05-20 細菌に基づくタンパク質送達
JP2020121375A Withdrawn JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達
JP2022069709A Active JP7509821B2 (ja) 2014-05-21 2022-04-20 細菌に基づくタンパク質送達

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2020121375A Withdrawn JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達
JP2022069709A Active JP7509821B2 (ja) 2014-05-21 2022-04-20 細菌に基づくタンパク質送達

Country Status (23)

Country Link
US (3) US10889823B2 (enExample)
EP (2) EP3145946B1 (enExample)
JP (3) JP6797025B2 (enExample)
KR (2) KR102648293B1 (enExample)
CN (2) CN115960919A (enExample)
AU (1) AU2015261905B2 (enExample)
BR (1) BR112016027196B1 (enExample)
CA (1) CA2948570C (enExample)
CY (1) CY1122701T1 (enExample)
DK (1) DK3145946T3 (enExample)
EA (1) EA201692025A1 (enExample)
ES (1) ES2754508T3 (enExample)
HR (1) HRP20192050T1 (enExample)
HU (1) HUE046025T2 (enExample)
IL (2) IL248827B (enExample)
LT (1) LT3145946T (enExample)
PL (1) PL3145946T3 (enExample)
PT (1) PT3145946T (enExample)
RS (1) RS59583B1 (enExample)
SG (1) SG11201609629YA (enExample)
SI (1) SI3145946T1 (enExample)
SM (1) SMT201900626T1 (enExample)
WO (1) WO2015177197A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3145946B1 (en) 2014-05-21 2019-08-14 Universität Basel Bacteria-based protein delivery
US12351805B2 (en) 2015-11-19 2025-07-08 Northeastern University Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria
AU2016358257B2 (en) 2015-11-19 2023-08-17 Universitat Basel Virulence attenuated bacteria for treatment of malignant solid tumors
US11365225B2 (en) * 2015-11-19 2022-06-21 President And Fellows Of Harvard College Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria
HRP20201792T1 (hr) 2015-11-19 2020-12-25 Universität Basel Isporuka proteina na bazi bakterija
PT3559022T (pt) * 2016-12-20 2021-08-19 Univ Basel Distribuição de proteínas baseada em bactérias com virulência atenuada
WO2018183850A2 (en) * 2017-03-31 2018-10-04 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods, systems, and compositions for inhibiting virulance of a/e family pathogens
CN107858367A (zh) * 2017-12-05 2018-03-30 复旦大学附属肿瘤医院 一种利用细菌靶向投递治疗性蛋白的系统及其应用
WO2020223601A1 (en) * 2019-05-01 2020-11-05 Innate Biologics Llc Immunomodulatory compositions and methods
US20220362361A1 (en) * 2019-10-18 2022-11-17 University Of Virginia Patent Foundation Compositions and methods for producing enhanced immune responses and rapid antibody production
CN111848803B (zh) * 2020-07-21 2022-04-08 珠海中科先进技术研究院有限公司 一种具有突出酸碱稳定性的磷脂酰肌醇蛋白聚糖3的纳米抗体及其制备方法
WO2022087856A1 (zh) * 2020-10-26 2022-05-05 南京吉芮康生物科技研究院有限公司 一种减毒沙门氏菌分泌表达rbd结构域蛋白的新型冠状病毒疫苗抗原递呈系统及其应用
CN114712496B (zh) * 2022-04-29 2023-10-13 中山大学·深圳 一种展示新抗原的细菌衍生外膜囊泡疫苗及制备方法和在制备癌症免疫治疗试剂盒中的应用
CN115896314A (zh) * 2022-07-14 2023-04-04 四川大学 一种基于lf-rpa的猕猴桃细菌性溃疡病菌的无设备、可视化检测方法
CN117511912B (zh) * 2023-12-22 2024-03-29 辉大(上海)生物科技有限公司 IscB多肽、包含其的系统及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965381A (en) * 1998-03-06 1999-10-12 Ludwig Institute For Cancer Research Delivery of proteins into eukaryotic cells with recombinant yersinia
WO2000002996A2 (en) 1998-07-10 2000-01-20 Cornell Research Foundation, Inc. Recombinant constructs and systems for secretion of proteins via type iii secretion systems
WO2002026819A2 (en) 2000-09-26 2002-04-04 Roger Williams Hospital Recombinant bcg vaccines for the prevention and treatment of cancer
US20040147719A1 (en) * 2001-03-26 2004-07-29 Guy Cornelis Type III bacterial strains for use in medicine
FR2862312B1 (fr) * 2003-11-13 2006-02-17 Univ Grenoble 1 Outil de transfert et de production de proteines mettant en oeuvre le systeme de secretion de type iii de pseudomonas
EP1905227A4 (en) 2005-07-15 2010-09-15 Laird Technologies Map Co Ltd OPENING AND CLOSING APPARATUS FOR SMALL PHOTOGRAPHIC DEVICES
WO2007044406A2 (en) 2005-10-04 2007-04-19 Ludwig Institute For Cancer Research Methods for stimulating an immune response using bacterial antigen delivery system
WO2008019183A2 (en) * 2006-05-18 2008-02-14 The Regents Of The University Of California Biopolymer and protein production using type iii secretion systems of gram negative bacteria
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EP1921149A1 (en) * 2006-11-13 2008-05-14 AEterna Zentaris GmbH Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof
JP5670875B2 (ja) * 2008-03-17 2015-02-18 ウニベルジテーツクリニクム ミュンスター カーゴ分子の送達ビヒクルおよび炎症反応を免疫調節するための生物学的治療剤としてのＹｏｐＭ
WO2010135563A1 (en) * 2009-05-22 2010-11-25 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium and methods of antigen and nucleic acid delivery
CN105764926A (zh) 2013-09-24 2016-07-13 梅迪塞纳医疗股份有限公司 白介素-4受体结合融合蛋白及其应用
US10143743B2 (en) 2013-11-18 2018-12-04 Yale University Non-replicating bacterial nanoparticle delivery system and methods of use
EP3145946B1 (en) 2014-05-21 2019-08-14 Universität Basel Bacteria-based protein delivery
HRP20201792T1 (hr) 2015-11-19 2020-12-25 Universität Basel Isporuka proteina na bazi bakterija
AU2016358257B2 (en) 2015-11-19 2023-08-17 Universitat Basel Virulence attenuated bacteria for treatment of malignant solid tumors
PT3559022T (pt) 2016-12-20 2021-08-19 Univ Basel Distribuição de proteínas baseada em bactérias com virulência atenuada

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