JP2017517257A5 - - Google Patents

Download PDF

Info

Publication number
JP2017517257A5
JP2017517257A5 JP2016568644A JP2016568644A JP2017517257A5 JP 2017517257 A5 JP2017517257 A5 JP 2017517257A5 JP 2016568644 A JP2016568644 A JP 2016568644A JP 2016568644 A JP2016568644 A JP 2016568644A JP 2017517257 A5 JP2017517257 A5 JP 2017517257A5
Authority
JP
Japan
Prior art keywords
protein
dna sequence
negative strain
effector protein
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016568644A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017517257A (ja
JP6797025B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2015/061086 external-priority patent/WO2015177197A1/en
Publication of JP2017517257A publication Critical patent/JP2017517257A/ja
Publication of JP2017517257A5 publication Critical patent/JP2017517257A5/ja
Application granted granted Critical
Publication of JP6797025B2 publication Critical patent/JP6797025B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016568644A 2014-05-21 2015-05-20 細菌に基づくタンパク質送達 Active JP6797025B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14169335 2014-05-21
EP14169335.8 2014-05-21
PCT/EP2015/061086 WO2015177197A1 (en) 2014-05-21 2015-05-20 Bacteria-based protein delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020121375A Division JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達

Publications (3)

Publication Number Publication Date
JP2017517257A JP2017517257A (ja) 2017-06-29
JP2017517257A5 true JP2017517257A5 (enExample) 2018-06-28
JP6797025B2 JP6797025B2 (ja) 2020-12-09

Family

ID=50771120

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2016568644A Active JP6797025B2 (ja) 2014-05-21 2015-05-20 細菌に基づくタンパク質送達
JP2020121375A Withdrawn JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達
JP2022069709A Active JP7509821B2 (ja) 2014-05-21 2022-04-20 細菌に基づくタンパク質送達

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2020121375A Withdrawn JP2020182478A (ja) 2014-05-21 2020-07-15 細菌に基づくタンパク質送達
JP2022069709A Active JP7509821B2 (ja) 2014-05-21 2022-04-20 細菌に基づくタンパク質送達

Country Status (23)

Country Link
US (3) US10889823B2 (enExample)
EP (2) EP3660034A1 (enExample)
JP (3) JP6797025B2 (enExample)
KR (2) KR102648293B1 (enExample)
CN (2) CN107001431B (enExample)
AU (1) AU2015261905B2 (enExample)
BR (1) BR112016027196B1 (enExample)
CA (1) CA2948570C (enExample)
CY (1) CY1122701T1 (enExample)
DK (1) DK3145946T3 (enExample)
EA (1) EA201692025A1 (enExample)
ES (1) ES2754508T3 (enExample)
HR (1) HRP20192050T1 (enExample)
HU (1) HUE046025T2 (enExample)
IL (2) IL248827B (enExample)
LT (1) LT3145946T (enExample)
PL (1) PL3145946T3 (enExample)
PT (1) PT3145946T (enExample)
RS (1) RS59583B1 (enExample)
SG (1) SG11201609629YA (enExample)
SI (1) SI3145946T1 (enExample)
SM (1) SMT201900626T1 (enExample)
WO (1) WO2015177197A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107001431B (zh) 2014-05-21 2022-11-01 巴塞尔大学 基于细菌的蛋白质递送
WO2017087827A1 (en) * 2015-11-19 2017-05-26 President And Fellows Of Harvard College Method of making recombinant silk andsilk-amyloid hybrid proteins using bacteria
SMT202000620T1 (it) * 2015-11-19 2021-01-05 Univ Basel Distribuzione di proteine basata su batteri
EA201890868A1 (ru) 2015-11-19 2018-12-28 Университет Базель Бактерии с ослабленной вирулентностью для лечения злокачественных солидных опухолей
US12351805B2 (en) 2015-11-19 2025-07-08 Northeastern University Method of making recombinant silk and silk-amyloid hybrid proteins using bacteria
JP6976351B2 (ja) 2016-12-20 2021-12-08 ウニヴェルズィテート・バーゼルUniversitat Basel 弱毒化細菌に基づくタンパク質送達
US11484603B2 (en) 2017-03-31 2022-11-01 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods, systems, and compositions for inhibiting virulence of A/E family pathogens
CN107858367A (zh) * 2017-12-05 2018-03-30 复旦大学附属肿瘤医院 一种利用细菌靶向投递治疗性蛋白的系统及其应用
CN114401730A (zh) * 2019-05-01 2022-04-26 因内特生物制品有限责任公司 免疫调节组合物和方法
EP4045672A4 (en) * 2019-10-18 2023-11-22 University of Virginia Patent Foundation COMPOSITIONS AND METHODS FOR PRODUCING ENHANCED IMMUNE RESPONSES AND RAPID ANTIBODY PRODUCTION
CN111848803B (zh) * 2020-07-21 2022-04-08 珠海中科先进技术研究院有限公司 一种具有突出酸碱稳定性的磷脂酰肌醇蛋白聚糖3的纳米抗体及其制备方法
WO2022087856A1 (zh) * 2020-10-26 2022-05-05 南京吉芮康生物科技研究院有限公司 一种减毒沙门氏菌分泌表达rbd结构域蛋白的新型冠状病毒疫苗抗原递呈系统及其应用
IL302334A (en) * 2020-10-27 2023-06-01 T3 Pharmaceuticals Ag Providing bacteria-based protein
CN114712496B (zh) * 2022-04-29 2023-10-13 中山大学·深圳 一种展示新抗原的细菌衍生外膜囊泡疫苗及制备方法和在制备癌症免疫治疗试剂盒中的应用
CN115896314A (zh) * 2022-07-14 2023-04-04 四川大学 一种基于lf-rpa的猕猴桃细菌性溃疡病菌的无设备、可视化检测方法
CN117511912B (zh) * 2023-12-22 2024-03-29 辉大(上海)生物科技有限公司 IscB多肽、包含其的系统及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965381A (en) * 1998-03-06 1999-10-12 Ludwig Institute For Cancer Research Delivery of proteins into eukaryotic cells with recombinant yersinia
US6596509B1 (en) * 1998-07-10 2003-07-22 Cornell Research Foundation, Inc. Recombinant constructs and systems for secretion of proteins via type III secretion systems
US20020160502A1 (en) 2000-09-26 2002-10-31 Roger Williams Hospital Recombinant BCG vaccines for the prevention and treatment of cancer
AU2002312778A1 (en) * 2001-03-26 2002-10-08 Universite Catholique De Louvain Type iii bacterial strains for use in medicine
FR2862312B1 (fr) * 2003-11-13 2006-02-17 Univ Grenoble 1 Outil de transfert et de production de proteines mettant en oeuvre le systeme de secretion de type iii de pseudomonas
JP2009501357A (ja) 2005-07-15 2009-01-15 レアード テクノロジーズ マップ カンパニー リミテッド 小型カメラ用開閉装置
US8357373B2 (en) 2005-10-04 2013-01-22 Ludwig Institute For Cancer Research Methods for stimulating an immune response using bacterial antigen delivery system
WO2008019183A2 (en) * 2006-05-18 2008-02-14 The Regents Of The University Of California Biopolymer and protein production using type iii secretion systems of gram negative bacteria
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EP1921149A1 (en) * 2006-11-13 2008-05-14 AEterna Zentaris GmbH Microorganisms as carriers of nucleotide sequences coding for antigens and protein toxins, process of manufacturing and uses thereof
EP2268313A2 (en) * 2008-03-17 2011-01-05 Universitätsklinikum Münster Yopm as delivery vehicle for cargo molecules and as biological therapeutic for immunomodulation of inflammatory reactions
WO2010135563A1 (en) * 2009-05-22 2010-11-25 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium and methods of antigen and nucleic acid delivery
JP6936934B2 (ja) 2013-09-24 2021-09-22 メディシナ セラピューティクス インコーポレイテッド インターロイキン−4受容体結合融合タンパク質及びその使用
US10143743B2 (en) 2013-11-18 2018-12-04 Yale University Non-replicating bacterial nanoparticle delivery system and methods of use
CN107001431B (zh) 2014-05-21 2022-11-01 巴塞尔大学 基于细菌的蛋白质递送
EA201890868A1 (ru) 2015-11-19 2018-12-28 Университет Базель Бактерии с ослабленной вирулентностью для лечения злокачественных солидных опухолей
SMT202000620T1 (it) 2015-11-19 2021-01-05 Univ Basel Distribuzione di proteine basata su batteri
JP6976351B2 (ja) 2016-12-20 2021-12-08 ウニヴェルズィテート・バーゼルUniversitat Basel 弱毒化細菌に基づくタンパク質送達

Similar Documents

Publication Publication Date Title
HRP20192050T1 (hr) Isporuka proteina na bazi bakterija
JP2016518833A5 (enExample)
Martin et al. Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A
JP2015212284A5 (enExample)
Wei et al. Facilitation of expression and purification of an antimicrobial peptide by fusion with baculoviral polyhedrin in Escherichia coli
AR108442A1 (es) Proteínas de fusión gdf15 y usos de estas
Ollis et al. Cytoplasmic membrane protonmotive force energizes periplasmic interactions between ExbD and TonB
MX387465B (es) Marcas genéticas de transgenes y métodos de uso.
Wu et al. Acid-induced type VI secretion system is regulated by ExoR-ChvG/ChvI signaling cascade in Agrobacterium tumefaciens
JP2005120106A5 (enExample)
WO2014172631A4 (en) Expression of biologically active proteins in a bacterial cell-free synthesis system using cell extracts with elevated levels of exogenous chaperones
EA201892554A1 (ru) Мутант cd200 и его применения
JP2015523066A5 (enExample)
MX2019003360A (es) Vectores de expresion para una secrecion de proteina mejorada.
WO2016135281A1 (en) Peptides for facilitating secretion and uses thereof
CN110036108A (zh) 一种细菌β-1,3-葡聚糖酶及其编码基因与应用
JP2016520531A5 (enExample)
JP2017529868A5 (enExample)
WO2020102642A8 (en) Endospore display platforms, products and methods
Zelena et al. Escherichia coli as a production host for novel enzymes from basidiomycota
JP2015536347A5 (enExample)
Orrapin et al. Recombinant expression of novel protegrin-1 dimer and LL-37-linker–histatin-5 hybrid peptide mediated biotin carboxyl carrier protein fusion partner
WO2008033451A3 (en) Protein aggregation domains from prions and methods of use thereof
Xiao et al. Peroxisome-targeted and tandem repeat multimer expressions of human antimicrobial peptide LL37 in Pichia pastoris
GB201102700D0 (en) Protein secretion