MX2009003188A - Polipeptidos hibridos inmunogenicos antiobesidad y composicion de vacuna antiobesidad que comprende los mismos. - Google Patents
Polipeptidos hibridos inmunogenicos antiobesidad y composicion de vacuna antiobesidad que comprende los mismos.Info
- Publication number
- MX2009003188A MX2009003188A MX2009003188A MX2009003188A MX2009003188A MX 2009003188 A MX2009003188 A MX 2009003188A MX 2009003188 A MX2009003188 A MX 2009003188A MX 2009003188 A MX2009003188 A MX 2009003188A MX 2009003188 A MX2009003188 A MX 2009003188A
- Authority
- MX
- Mexico
- Prior art keywords
- obese
- cell epitope
- immunogenic hybrid
- vaccine composition
- expression vector
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se describe un polipéptido híbrido inmunogénico para la prevención y el tratamiento de la obesidad, en el cual un péptido mimético de un epitopo del linfocito B de la apolipoproteína B-100; un epitopo del linfocito T auxiliar del virus de la rabia o un epitopo del linfocito T auxiliar del antígeno de la superficie del virus de la hepatitis B y un fragmento del péptido C terminal de la apolipoproteína CII de ratón o un péptido mimético de un epitopo del linfocito B de la apolipoproteína B-100 están fusionados unos con otros en ese orden, en la dirección del término N hacia el término C del mismo. También, se describe una composición de vacuna para la prevención y el tratamiento de la obesidad, que comprende el polipéptido híbrido inmunogénico, junto con un polinucleótido que codifica el polipéptido híbrido inmunogénico, un vector de expresión recombinante que porta el polinucleótido, una célula hospedera que ancla el vector de expresión recombinante y un método para producir el polipéptido híbrido inmunogénico, cultivando la célula hospedera transformada con el vector de expresión recombinante.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20060093130 | 2006-09-25 | ||
| PCT/KR2007/004692 WO2008038990A1 (en) | 2006-09-25 | 2007-09-21 | Anti-obese immunogenic hybrid polypeptides and anti-obese vaccine composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009003188A true MX2009003188A (es) | 2009-05-22 |
Family
ID=39230370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009003188A MX2009003188A (es) | 2006-09-25 | 2007-09-21 | Polipeptidos hibridos inmunogenicos antiobesidad y composicion de vacuna antiobesidad que comprende los mismos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20110002955A1 (es) |
| EP (1) | EP2076544A4 (es) |
| JP (1) | JP2010504094A (es) |
| KR (2) | KR100956893B1 (es) |
| CN (1) | CN101516915A (es) |
| AU (1) | AU2007300842B2 (es) |
| BR (1) | BRPI0717223A2 (es) |
| CA (1) | CA2664529A1 (es) |
| MX (1) | MX2009003188A (es) |
| RU (1) | RU2418005C2 (es) |
| WO (1) | WO2008038990A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101476383B1 (ko) * | 2011-07-12 | 2014-12-24 | 한국생명공학연구원 | 단백질 분비융합인자를 포함하는 재조합 벡터 및 이를 이용한 비만백신 단백질의 대량생산 방법 |
| JP2019527192A (ja) | 2016-05-31 | 2019-09-26 | カーディオバックス リミテッド ライアビリティ カンパニー | 全身性エリテマトーデスの診断及び治療方法 |
| US10858422B2 (en) | 2016-05-31 | 2020-12-08 | Abcentra, Llc | Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody |
| KR102261457B1 (ko) * | 2020-07-22 | 2021-06-09 | (주)쓰리에이치바이오 | 면역 치료제용 펩타이드 |
| EP4368638A3 (en) * | 2020-07-22 | 2024-07-31 | 3H Bio. Co., Ltd. | Peptide for immunotherapeutic agent |
| WO2024040025A2 (en) * | 2022-08-19 | 2024-02-22 | University Of Washington | Th2 vaccine-based prevention and treatment of inflammation in obesity |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60193926A (ja) | 1984-03-15 | 1985-10-02 | Tokyo Daigaku | 単クローン性抗ヒトアポリポ蛋白質ｂ１００抗体 |
| US5837249A (en) * | 1985-04-19 | 1998-11-17 | The Wistar Institute | Method for generating an immunogenic T cell response protective against a virus |
| US5693325A (en) * | 1994-03-15 | 1997-12-02 | Molecumetics, Ltd. | Peptide vaccines and methods relating thereto |
| KR0135708B1 (ko) * | 1994-05-31 | 1998-04-23 | 김은영 | 인간 혈중 아포지단백질 비-100(b-100)에 대한 신규 단일클론 항체 및 이들의 생산을 위한 재조합 하이브리도마 세포주 |
| GB0121171D0 (en) | 2001-08-31 | 2001-10-24 | Glaxosmithkline Biolog Sa | Vaccine |
| KR100472841B1 (ko) | 2000-09-04 | 2005-03-07 | (주)에스제이바이오메드 | 아포지단백질 비-100의 에피토프에 대한 모조 펩타이드,그들의 연쇄물 또는 변형체와 이들을 함유하는 백신 조성물 |
| CN1231262C (zh) * | 2000-09-04 | 2005-12-14 | 金晓骏 | 载脂蛋白b－100表位的模拟肽、其多联体和修饰肽,以及含有这些肽的疫苗组合物 |
| US7241861B2 (en) * | 2001-05-15 | 2007-07-10 | Japan Immunoresearch Laboratories Co., Ltd. | High density lipoprotein-reactive peptides |
| CA2496409A1 (en) * | 2002-08-30 | 2004-03-11 | Glaxo Group Limited | Immunogenic composition comprising an il-13 element and t cell epitopes, and its therapeutic use |
| AU2004263303A1 (en) * | 2003-08-07 | 2005-02-17 | F. Hoffmann-La Roche Ag | RA antigenic peptides |
| KR100639397B1 (ko) * | 2004-03-18 | 2006-10-26 | (주)에스제이바이오메드 | 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물 |
-
2007
- 2007-09-21 CA CA002664529A patent/CA2664529A1/en not_active Abandoned
- 2007-09-21 EP EP07808454A patent/EP2076544A4/en not_active Withdrawn
- 2007-09-21 BR BRPI0717223-0A2A patent/BRPI0717223A2/pt not_active IP Right Cessation
- 2007-09-21 WO PCT/KR2007/004692 patent/WO2008038990A1/en active Application Filing
- 2007-09-21 US US12/442,760 patent/US20110002955A1/en not_active Abandoned
- 2007-09-21 KR KR1020070097000A patent/KR100956893B1/ko active IP Right Grant
- 2007-09-21 RU RU2009115688/10A patent/RU2418005C2/ru not_active IP Right Cessation
- 2007-09-21 MX MX2009003188A patent/MX2009003188A/es not_active Application Discontinuation
- 2007-09-21 AU AU2007300842A patent/AU2007300842B2/en not_active Ceased
- 2007-09-21 JP JP2009529132A patent/JP2010504094A/ja not_active Ceased
- 2007-09-21 CN CNA2007800356531A patent/CN101516915A/zh active Pending
-
2010
- 2010-02-25 KR KR1020100017360A patent/KR100970178B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007300842B2 (en) | 2011-01-27 |
| CN101516915A (zh) | 2009-08-26 |
| JP2010504094A (ja) | 2010-02-12 |
| KR100970178B1 (ko) | 2010-07-14 |
| BRPI0717223A2 (pt) | 2013-09-24 |
| KR20100033395A (ko) | 2010-03-29 |
| KR20080027753A (ko) | 2008-03-28 |
| RU2009115688A (ru) | 2010-11-10 |
| US20110002955A1 (en) | 2011-01-06 |
| EP2076544A4 (en) | 2009-11-11 |
| CA2664529A1 (en) | 2008-04-03 |
| AU2007300842A1 (en) | 2008-04-03 |
| KR100956893B1 (ko) | 2010-05-11 |
| RU2418005C2 (ru) | 2011-05-10 |
| WO2008038990A1 (en) | 2008-04-03 |
| EP2076544A1 (en) | 2009-07-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9969986B2 (en) | Virus like particle comprising modified envelope protein E3 | |
| HRP20200871T1 (hr) | Izmjenjeni rsv f proteini i postupci njihove uporabe | |
| WO2007106476A3 (en) | Compositions and methods for enhancing the immunogenicity of antigens | |
| MX2009003188A (es) | Polipeptidos hibridos inmunogenicos antiobesidad y composicion de vacuna antiobesidad que comprende los mismos. | |
| JP2005120106A5 (es) | ||
| NZ606427A (en) | Extended recombinant polypeptides and compositions comprising same | |
| JP2007513634A5 (es) | ||
| MY150105A (en) | A novel surface exposed haemophilus influenzae protein (protein e; pe) | |
| UA98620C2 (uk) | Атенуйований вірус класичної лихоманки свиней, що містить модифікований глікопротеїн е2 | |
| JP2013529078A5 (es) | ||
| WO2007095320A4 (en) | Hpv antigens, vaccine compositions, and related methods | |
| JP2015535816A5 (es) | ||
| JP2012095652A5 (es) | ||
| JP2013531477A5 (es) | ||
| UA108081C2 (uk) | Модифікація рекомбінантного аденовірусу імуногенними епітопами білка circumsporozoite плазмодія | |
| JP2014503198A5 (es) | ||
| CA2636075A1 (en) | Chimaeric fusion protein with superior chaperone and folding activities | |
| US20160200775A1 (en) | Virus like particle comprising modified envelope protein e3 | |
| MX340772B (es) | Medios y metodos para fabricar neurotoxina altamente pura. | |
| NZ594638A (en) | Antibodies containing therapeutic tpo/epo mimetic peptides for treatment of thrombocytopenia type conditions | |
| WO2008127179A8 (en) | Fusion protein vaccine | |
| JP2010279373A5 (es) | ||
| JP2022547107A (ja) | インフルエンザウイルスワクチン及びその使用 | |
| MX2021007285A (es) | Particulas similares a virus del cmv modificadas por fusion. | |
| TW201008576A (en) | New fusion proteins and their use for the preparation of vaccines against hepatitis C |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |