JP2010273685A5 - - Google Patents

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Publication number
JP2010273685A5
JP2010273685A5 JP2010166570A JP2010166570A JP2010273685A5 JP 2010273685 A5 JP2010273685 A5 JP 2010273685A5 JP 2010166570 A JP2010166570 A JP 2010166570A JP 2010166570 A JP2010166570 A JP 2010166570A JP 2010273685 A5 JP2010273685 A5 JP 2010273685A5
Authority
JP
Japan
Prior art keywords
protein
antibody
seq
vertebrate
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010166570A
Other languages
English (en)
Japanese (ja)
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JP2010273685A (ja
Filing date
Publication date
Priority claimed from US08/400,159 external-priority patent/US5869282A/en
Application filed filed Critical
Publication of JP2010273685A publication Critical patent/JP2010273685A/ja
Publication of JP2010273685A5 publication Critical patent/JP2010273685A5/ja
Withdrawn legal-status Critical Current

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JP2010166570A 1995-03-07 2010-07-23 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法 Withdrawn JP2010273685A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/400,159 US5869282A (en) 1991-12-11 1995-03-07 Nucleotide and protein sequences of the serrate gene and methods based thereon

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007260391A Division JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013023179A Division JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Publications (2)

Publication Number Publication Date
JP2010273685A JP2010273685A (ja) 2010-12-09
JP2010273685A5 true JP2010273685A5 (enExample) 2011-07-14

Family

ID=23582455

Family Applications (4)

Application Number Title Priority Date Filing Date
JP8527061A Withdrawn JPH11507203A (ja) 1995-03-07 1996-03-07 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2007260391A Withdrawn JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2010166570A Withdrawn JP2010273685A (ja) 1995-03-07 2010-07-23 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2013023179A Withdrawn JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP8527061A Withdrawn JPH11507203A (ja) 1995-03-07 1996-03-07 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法
JP2007260391A Withdrawn JP2008099687A (ja) 1995-03-07 2007-10-03 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013023179A Withdrawn JP2013150605A (ja) 1995-03-07 2013-02-08 脊椎動物Serrate遺伝子のヌクレオチドおよびタンパク質配列およびそれらに基づく方法

Country Status (11)

Country Link
US (1) US5869282A (enExample)
EP (1) EP0813545B1 (enExample)
JP (4) JPH11507203A (enExample)
AT (1) ATE442381T1 (enExample)
AU (1) AU718955B2 (enExample)
CA (1) CA2214830C (enExample)
DE (1) DE69638022D1 (enExample)
DK (1) DK0813545T3 (enExample)
ES (1) ES2333384T3 (enExample)
PT (1) PT813545E (enExample)
WO (1) WO1996027610A1 (enExample)

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US6436650B1 (en) 1997-07-23 2002-08-20 Yale University Activated forms of notch and methods based thereon
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AU1054900A (en) * 1998-10-30 2000-05-22 Smith & Nephew Plc Compositions comprising notch receptor manipulating agents
US8084258B2 (en) * 1999-07-12 2011-12-27 University Of Basel Manipulation of tissue of organ type using the notch pathway
GB9927328D0 (en) 1999-11-18 2000-01-12 Lorantis Ltd Immunotherapy
US6984522B2 (en) * 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
US20050089518A1 (en) * 2001-12-07 2005-04-28 Clarke Michael F. Prospective identification and characterization of breast cancer stem cells
AU2001288628A1 (en) * 2000-08-31 2002-03-13 Loyola University Chicago Method and reagents for treatment of skin disorders by modulating the notch pathway
AU2001297693A1 (en) * 2000-12-08 2002-09-12 Coley Pharmaceutical Gmbh Cpg-like nucleic acids and methods of use thereof
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GB0118155D0 (en) 2001-07-25 2001-09-19 Lorantis Ltd Superantigen
US20030185829A1 (en) * 2002-03-12 2003-10-02 Erich Koller Jagged 2 inhibitors for inducing apoptosis
US20040102401A1 (en) * 2002-11-22 2004-05-27 Isis Pharmaceuticals Inc. Modulation of jagged 1 expression
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EP2003196A3 (en) * 2003-06-09 2009-01-07 The Regents of the University of Michigan Compositions and methods for treating and diagnosing cancer
WO2005074633A2 (en) * 2004-02-03 2005-08-18 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
US20060252073A1 (en) * 2005-04-18 2006-11-09 Regents Of The University Of Michigan Compositions and methods for the treatment of cancer
WO2006138275A2 (en) * 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) * 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
PT2500360E (pt) 2005-10-31 2015-10-15 Oncomed Pharm Inc Composições e métodos para diagnóstico e tratamento do cancro
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
US7723112B2 (en) * 2005-10-31 2010-05-25 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
WO2008121102A2 (en) * 2006-02-21 2008-10-09 The Regents Of The University Of Michigan Hedgehog signaling pathway antagonist cancer treatment
WO2008092002A2 (en) * 2007-01-24 2008-07-31 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing pancreatic cancer
WO2008140826A1 (en) * 2007-05-15 2008-11-20 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
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US8945569B2 (en) 2009-11-19 2015-02-03 Oncomed Pharmaceuticals, Inc. Jagged-binding agents and uses thereof
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CN102971337B (zh) 2010-04-01 2016-09-21 昂考梅德药品有限公司 卷曲蛋白结合药剂及其应用
WO2011127472A1 (en) 2010-04-09 2011-10-13 Fred Hutchinson Cancer Research Center Compositions and methods for providing hematopoietic function
JP6165627B2 (ja) 2010-04-09 2017-07-19 フレッド ハッチンソン キャンサー リサーチ センター Hlaの適合なしに造血機能を提供するための組成物および方法
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JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Wnt経路インヒビターによる処置の方法およびモニタリング
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JP6734283B2 (ja) 2015-01-21 2020-08-05 フレッド ハッチンソン キャンサー リサーチ センター 遺伝子治療用ポイントオブケア及び/又はポータブルプラットフォーム
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JP2018537472A (ja) 2015-12-04 2018-12-20 フレッド ハッチンソン キャンサー リサーチ センター 増殖造血幹細胞/前駆細胞集団の利用
WO2020037326A1 (en) 2018-08-17 2020-02-20 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by downregulating foxo
CA3109647A1 (en) * 2018-08-17 2020-02-20 Frequency Therapeutics, Inc. Compositions and methods for generating hair cells by upregulating jag-1
CN112680471B (zh) * 2019-10-17 2023-08-01 华南农业大学 ZmSPL基因在调控玉米柱头乳突细胞发育中的应用

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WO1993012141A1 (en) * 1991-12-11 1993-06-24 Yale University Nucleotide and protein sequences of the serrate gene and methods based thereon
US5786158A (en) * 1992-04-30 1998-07-28 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
US6337387B1 (en) * 1995-11-17 2002-01-08 Asahi Kasei Kabushiki Kaisha Differentiation-suppressive polypeptide
JP2000512134A (ja) * 1996-05-31 2000-09-19 ザ ナショナル アメリカン レッド クロス Jagged/Notchタンパク質および核酸に基づく治療および診断の方法および組成物
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