|
US845948A
(en)
|
1906-11-22 |
1907-03-05 |
Raymond A Hall |
Soldering compound.
|
|
US2103001A
(en)
|
1933-08-28 |
1937-12-21 |
E S Evans And Sons |
Windshield wiper mechanism
|
|
JPS5927900A
(ja)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
固定化オリゴヌクレオチド
|
|
FR2540122B1
(fr)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
|
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
|
US5118800A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
Oligonucleotides possessing a primary amino group in the terminal nucleotide
|
|
FR2567892B1
(fr)
|
1984-07-19 |
1989-02-17 |
Centre Nat Rech Scient |
Nouveaux oligonucleotides, leur procede de preparation et leurs applications comme mediateurs dans le developpement des effets des interferons
|
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
|
US5034506A
(en)
|
1985-03-15 |
1991-07-23 |
Anti-Gene Development Group |
Uncharged morpholino-based polymers having achiral intersubunit linkages
|
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
|
JPS638396A
(ja)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
ポリ標識化オリゴヌクレオチド誘導体
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
|
DE3738460A1
(de)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
Modifizierte oligonukleotide
|
|
CA1327358C
(en)
|
1987-11-17 |
1994-03-01 |
Morio Fujiu |
Fluoro cytidine derivatives
|
|
US5563250A
(en)
|
1987-12-02 |
1996-10-08 |
Neorx Corporation |
Cleavable conjugates for the delivery and release of agents in native form
|
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
|
US5591722A
(en)
|
1989-09-15 |
1997-01-07 |
Southern Research Institute |
2'-deoxy-4'-thioribonucleosides and their antiviral activity
|
|
EP0497875B1
(en)
|
1989-10-24 |
2000-03-22 |
Isis Pharmaceuticals, Inc. |
2' modified oligonucleotides
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
|
WO1991013080A1
(en)
|
1990-02-20 |
1991-09-05 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
|
GB9009980D0
(en)
|
1990-05-03 |
1990-06-27 |
Amersham Int Plc |
Phosphoramidite derivatives,their preparation and the use thereof in the incorporation of reporter groups on synthetic oligonucleotides
|
|
ATE167523T1
(de)
|
1990-05-11 |
1998-07-15 |
Microprobe Corp |
Teststreifen zum eintauchen für nukleinsäure- hybridisierungsassays und verfahren zur kovalenten immobilisierung von oligonucleotiden
|
|
US5637459A
(en)
*
|
1990-06-11 |
1997-06-10 |
Nexstar Pharmaceuticals, Inc. |
Systematic evolution of ligands by exponential enrichment: chimeric selex
|
|
US5602240A
(en)
|
1990-07-27 |
1997-02-11 |
Ciba Geigy Ag. |
Backbone modified oligonucleotide analogs
|
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5489677A
(en)
|
1990-07-27 |
1996-02-06 |
Isis Pharmaceuticals, Inc. |
Oligonucleoside linkages containing adjacent oxygen and nitrogen atoms
|
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
|
US6140496A
(en)
|
1990-10-09 |
2000-10-31 |
Benner; Steven Albert |
Precursors for deoxyribonucleotides containing non-standard nucleosides
|
|
CA2095212A1
(en)
|
1990-11-08 |
1992-05-09 |
Sudhir Agrawal |
Incorporation of multiple reporter groups on synthetic oligonucleotides
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5714331A
(en)
|
1991-05-24 |
1998-02-03 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
|
|
US5719262A
(en)
|
1993-11-22 |
1998-02-17 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having amino acid side chains
|
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
|
DE59208572D1
(de)
|
1991-10-17 |
1997-07-10 |
Ciba Geigy Ag |
Bicyclische Nukleoside, Oligonukleotide, Verfahren zu deren Herstellung und Zwischenprodukte
|
|
US5359044A
(en)
|
1991-12-13 |
1994-10-25 |
Isis Pharmaceuticals |
Cyclobutyl oligonucleotide surrogates
|
|
CA2126691C
(en)
*
|
1991-12-24 |
2003-05-06 |
Phillip Dan Cook |
Gapped 2' modified oligonucleotides
|
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
|
FR2687679B1
(fr)
|
1992-02-05 |
1994-10-28 |
Centre Nat Rech Scient |
Oligothionucleotides.
|
|
CA2076465C
(en)
|
1992-03-25 |
2002-11-26 |
Ravi V. J. Chari |
Cell binding agent conjugates of analogues and derivatives of cc-1065
|
|
US5505931A
(en)
|
1993-03-04 |
1996-04-09 |
The Dow Chemical Company |
Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents
|
|
EP0577558A2
(de)
|
1992-07-01 |
1994-01-05 |
Ciba-Geigy Ag |
Carbocyclische Nukleoside mit bicyclischen Ringen, Oligonukleotide daraus, Verfahren zu deren Herstellung, deren Verwendung und Zwischenproduckte
|
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
|
ATE155467T1
(de)
|
1993-03-30 |
1997-08-15 |
Sanofi Sa |
Acyclische nucleosid analoge und sie enthaltende oligonucleotidsequenzen
|
|
DE4311944A1
(de)
|
1993-04-10 |
1994-10-13 |
Degussa |
Umhüllte Natriumpercarbonatpartikel, Verfahren zu deren Herstellung und sie enthaltende Wasch-, Reinigungs- und Bleichmittelzusammensetzungen
|
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
|
US5446137B1
(en)
|
1993-12-09 |
1998-10-06 |
Behringwerke Ag |
Oligonucleotides containing 4'-substituted nucleotides
|
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
|
US5627053A
(en)
|
1994-03-29 |
1997-05-06 |
Ribozyme Pharmaceuticals, Inc. |
2'deoxy-2'-alkylnucleotide containing nucleic acid
|
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5585108A
(en)
|
1994-12-30 |
1996-12-17 |
Nanosystems L.L.C. |
Formulations of oral gastrointestinal therapeutic agents in combination with pharmaceutically acceptable clays
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5707807A
(en)
|
1995-03-28 |
1998-01-13 |
Research Development Corporation Of Japan |
Molecular indexing for expressed gene analysis
|
|
US5889136A
(en)
|
1995-06-09 |
1999-03-30 |
The Regents Of The University Of Colorado |
Orthoester protecting groups in RNA synthesis
|
|
US6265389B1
(en)
|
1995-08-31 |
2001-07-24 |
Alkermes Controlled Therapeutics, Inc. |
Microencapsulation and sustained release of oligonucleotides
|
|
US6630351B1
(en)
|
1999-06-07 |
2003-10-07 |
Mirus Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
|
WO1997030064A1
(en)
|
1996-02-16 |
1997-08-21 |
Stichting Rega Vzw |
Hexitol containing oligonucleotides and their use in antisense strategies
|
|
WO1998000194A2
(en)
|
1996-06-28 |
1998-01-08 |
Sontra Medical, L.P. |
Ultrasound enhancement of transdermal transport
|
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
|
WO1998031700A1
(en)
|
1997-01-21 |
1998-07-23 |
The General Hospital Corporation |
Selection of proteins using rna-protein fusions
|
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
|
JP3756313B2
(ja)
|
1997-03-07 |
2006-03-15 |
武 今西 |
新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
|
|
US20030073640A1
(en)
|
1997-07-23 |
2003-04-17 |
Ribozyme Pharmaceuticals, Inc. |
Novel compositions for the delivery of negatively charged molecules
|
|
US6794499B2
(en)
|
1997-09-12 |
2004-09-21 |
Exiqon A/S |
Oligonucleotide analogues
|
|
US6004573A
(en)
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
US6548633B1
(en)
|
1998-12-22 |
2003-04-15 |
Genset, S.A. |
Complementary DNA's encoding proteins with signal peptides
|
|
US6517869B1
(en)
|
1997-12-12 |
2003-02-11 |
Expression Genetics, Inc. |
Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
|
|
WO1999029758A1
(en)
|
1997-12-12 |
1999-06-17 |
Samyang Corporation |
Positively-charged poly[alpha-(omega-aminoalkyl)glycolic acid] for the delivery of a bioactive agent via tissue and cellular uptake
|
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
ES2356342T3
(es)
|
1998-01-05 |
2011-04-07 |
The University Of Washington |
Mejora de transporte utilizando agentes de alteración de membrana.
|
|
EP1053019B1
(en)
|
1998-01-07 |
2003-12-03 |
Debio Recherche Pharmaceutique S.A. |
Degradable heterobifunctional poly(ethylene glycol) acrylates and gels and conjugates derived therefrom
|
|
US8287483B2
(en)
|
1998-01-08 |
2012-10-16 |
Echo Therapeutics, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
CA2317777C
(en)
|
1998-01-08 |
2005-05-03 |
Sontra Medical, Inc. |
Sonophoretic enhanced transdermal transport
|
|
US6426086B1
(en)
|
1998-02-03 |
2002-07-30 |
The Regents Of The University Of California |
pH-sensitive, serum-stable liposomes
|
|
EP1072678A4
(en)
|
1998-04-23 |
2006-09-27 |
Takara Bio Inc |
PROCESS FOR SYNTHESIZING DNA
|
|
US6177274B1
(en)
|
1998-05-20 |
2001-01-23 |
Expression Genetics, Inc. |
Hepatocyte targeting polyethylene glyco-grafted poly-L-lysine polymeric gene carrier
|
|
US7091192B1
(en)
|
1998-07-01 |
2006-08-15 |
California Institute Of Technology |
Linear cyclodextrin copolymers
|
|
EP1117720A4
(en)
|
1998-07-13 |
2001-11-14 |
Expression Genetics Inc |
POLYESTER POLY-L-LYSINE ANALOG USED AS A BIODEGRADABLE SOLUBLE GENE CONVEYOR
|
|
US6222030B1
(en)
|
1998-08-03 |
2001-04-24 |
Agilent Technologies, Inc. |
Solid phase synthesis of oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
|
|
US20040171980A1
(en)
|
1998-12-18 |
2004-09-02 |
Sontra Medical, Inc. |
Method and apparatus for enhancement of transdermal transport
|
|
US6255476B1
(en)
|
1999-02-22 |
2001-07-03 |
Pe Corporation (Ny) |
Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
EP1156781B1
(en)
|
1999-02-26 |
2005-06-08 |
Chiron Corporation |
Microemulsions with adsorbed macromolecules and microparticles
|
|
US8410248B2
(en)
|
1999-03-12 |
2013-04-02 |
Human Genome Sciences Inc. |
HWBAO62 polypeptides
|
|
US7084125B2
(en)
|
1999-03-18 |
2006-08-01 |
Exiqon A/S |
Xylo-LNA analogues
|
|
CA2372085C
(en)
|
1999-05-04 |
2009-10-27 |
Exiqon A/S |
L-ribo-lna analogues
|
|
US7098032B2
(en)
|
2001-01-02 |
2006-08-29 |
Mirus Bio Corporation |
Compositions and methods for drug delivery using pH sensitive molecules
|
|
CA2311201A1
(en)
|
1999-08-05 |
2001-02-05 |
Genset S.A. |
Ests and encoded human proteins
|
|
US6245929B1
(en)
|
1999-12-20 |
2001-06-12 |
General Electric Company |
Catalyst composition and method for producing diaryl carbonates, using bisphosphines
|
|
WO2001051092A2
(en)
|
2000-01-07 |
2001-07-19 |
University Of Washington |
Enhanced transport of agents using membrane disruptive agents
|
|
US7491805B2
(en)
|
2001-05-18 |
2009-02-17 |
Sirna Therapeutics, Inc. |
Conjugates and compositions for cellular delivery
|
|
US7833992B2
(en)
|
2001-05-18 |
2010-11-16 |
Merck Sharpe & Dohme |
Conjugates and compositions for cellular delivery
|
|
WO2001062827A2
(en)
|
2000-02-22 |
2001-08-30 |
Shearwater Corporation |
N-maleimidyl polymer derivatives
|
|
US6368801B1
(en)
|
2000-04-12 |
2002-04-09 |
Molecular Staging, Inc. |
Detection and amplification of RNA using target-mediated ligation of DNA by RNA ligase
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
US6696038B1
(en)
|
2000-09-14 |
2004-02-24 |
Expression Genetics, Inc. |
Cationic lipopolymer as biocompatible gene delivery agent
|
|
DK1334109T3
(da)
|
2000-10-04 |
2006-10-09 |
Santaris Pharma As |
Forbedret syntese af purin-blokerede nukleinsyre-analoger
|
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
|
US6649138B2
(en)
|
2000-10-13 |
2003-11-18 |
Quantum Dot Corporation |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
|
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
|
US6897196B1
(en)
|
2001-02-07 |
2005-05-24 |
The Regents Of The University Of California |
pH sensitive lipids based on ortho ester linkers, composition and method
|
|
US6652886B2
(en)
|
2001-02-16 |
2003-11-25 |
Expression Genetics |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
|
|
US8137911B2
(en)
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
|
ES2340532T3
(es)
|
2001-06-05 |
2010-06-04 |
Curevac Gmbh |
Arnm con un contenido g/c aumentado que codifica para un antigeno bacteriano y utilizacion del mismo.
|
|
US6586524B2
(en)
|
2001-07-19 |
2003-07-01 |
Expression Genetics, Inc. |
Cellular targeting poly(ethylene glycol)-grafted polymeric gene carrier
|
|
EP1412065A2
(en)
|
2001-07-27 |
2004-04-28 |
President And Fellows Of Harvard College |
Laminar mixing apparatus and methods
|
|
CA2462144C
(en)
|
2001-09-28 |
2016-09-20 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Micro-rna molecules
|
|
EP1443905A4
(en)
|
2001-10-03 |
2010-06-23 |
Univ Johns Hopkins |
COMPOSITIONS FOR ORAL GENE THERAPY AND METHOD OF USE THEREOF
|
|
WO2003042383A1
(en)
|
2001-11-14 |
2003-05-22 |
Toyo Boseki Kabushiki Kaisha |
Dna synthesis promoters, dna polymerase-associated factors and utilization thereof
|
|
CA2409775C
(en)
|
2001-12-03 |
2010-07-13 |
F. Hoffmann-La Roche Ag |
Reversibly modified thermostable enzymes for dna synthesis and amplification in vitro
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
PT1474109E
(pt)
|
2001-12-21 |
2010-10-25 |
Alcon Inc |
Utilização de nanopartículas inorgânicas sintéticas como veículos em medicamentos oftálmicos
|
|
US20050222064A1
(en)
|
2002-02-20 |
2005-10-06 |
Sirna Therapeutics, Inc. |
Polycationic compositions for cellular delivery of polynucleotides
|
|
EP1485070A1
(en)
|
2002-03-13 |
2004-12-15 |
Novartis AG |
Pharmaceutical microparticles
|
|
US7074596B2
(en)
|
2002-03-25 |
2006-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Synthesis and use of anti-reverse mRNA cap analogues
|
|
GB0209539D0
(en)
|
2002-04-26 |
2002-06-05 |
Avecia Ltd |
Monomer Polymer and process
|
|
AU2003217531A1
(en)
|
2002-05-02 |
2003-11-17 |
Massachusetts Eye And Ear Infirmary |
Ocular drug delivery systems and use thereof
|
|
US7374930B2
(en)
|
2002-05-21 |
2008-05-20 |
Expression Genetics, Inc. |
GLP-1 gene delivery for the treatment of type 2 diabetes
|
|
EP1386925A1
(en)
|
2002-07-31 |
2004-02-04 |
Girindus AG |
Method for preparing oligonucleotides
|
|
US6653468B1
(en)
|
2002-07-31 |
2003-11-25 |
Isis Pharmaceuticals, Inc. |
Universal support media for synthesis of oligomeric compounds
|
|
JP2006502301A
(ja)
|
2002-09-06 |
2006-01-19 |
インサート セラピューティクス インコーポレイテッド |
治療剤配送のためのシクロデキストリン基材重合体
|
|
US7534872B2
(en)
|
2002-09-27 |
2009-05-19 |
Syngen, Inc. |
Compositions and methods for the use of FMOC derivatives in DNA/RNA synthesis
|
|
EP1567169A4
(en)
|
2002-11-04 |
2009-10-21 |
Xenoport Inc |
GEMCITABINE PROMOTERS, THEIR PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
|
|
WO2004048593A2
(en)
|
2002-11-21 |
2004-06-10 |
Epicentre Technologies |
Methods for using riboprimers for strand displacement replication of target sequences
|
|
MXPA05007652A
(es)
*
|
2003-01-16 |
2006-02-22 |
Hybridon Inc |
Modulacion de propiedades inmunoestimulantes de compuestos basados en oligonucleotido mediante la utilizacion de dinucleotidos inmunoestimulantes modificados.
|
|
JP2006525405A
(ja)
|
2003-05-05 |
2006-11-09 |
ベン‐グリオン ユニバーシティ オブ ザ ネゲヴ リサーチ アンド デベロップメント オーソリティ |
注入可能な架橋されたポリマー調製物およびその使用
|
|
WO2005007819A2
(en)
|
2003-07-09 |
2005-01-27 |
Wisconsin Alumni Research Foundation |
Charge-dynamic polymers and delivery of anionic compounds
|
|
KR100992646B1
(ko)
|
2003-07-09 |
2010-11-05 |
제이에스알 가부시끼가이샤 |
파장판
|
|
GB0316089D0
(en)
|
2003-07-09 |
2003-08-13 |
Xo Bioscience Ltd |
Differentiation method
|
|
US8506967B2
(en)
|
2003-07-11 |
2013-08-13 |
Novavax, Inc. |
Functional influenza virus like particles (VLPs)
|
|
US8592197B2
(en)
|
2003-07-11 |
2013-11-26 |
Novavax, Inc. |
Functional influenza virus-like particles (VLPs)
|
|
CA2533701A1
(en)
|
2003-07-31 |
2005-02-17 |
Isis Pharmaceuticals, Inc. |
Oligomeric compounds and compositions for use in modulation of small non-coding rnas
|
|
US20050130201A1
(en)
|
2003-10-14 |
2005-06-16 |
Dharmacon, Inc. |
Splint-assisted enzymatic synthesis of polyribounucleotides
|
|
WO2005084180A2
(en)
|
2003-12-19 |
2005-09-15 |
University Of Cincinnati |
Polyamides and polyamide complexes for delivery of oligonucleotide decoys
|
|
US8957034B2
(en)
|
2004-01-28 |
2015-02-17 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
|
KR20070044805A
(ko)
|
2004-04-15 |
2007-04-30 |
키아스마, 인코포레이티드 |
생물학적 장벽 투과를 촉진시킬 수 있는 조성물
|
|
WO2005108411A2
(en)
|
2004-05-05 |
2005-11-17 |
Isis Pharmaceuticals, Inc. |
Substituted pixyl protecting groups for oligonucleotide synthesis
|
|
US20080103053A1
(en)
|
2005-11-22 |
2008-05-01 |
Helicos Biosciences Corporation |
Methods and compositions for sequencing a nucleic acid
|
|
JP2008502739A
(ja)
|
2004-06-11 |
2008-01-31 |
トラスティーズ オブ タフツ カレッジ |
絹に基づく薬物送達システム
|
|
US7527947B2
(en)
|
2004-06-14 |
2009-05-05 |
Novozymes A/S |
Signal peptide for producing a polypeptide
|
|
US8057821B2
(en)
|
2004-11-03 |
2011-11-15 |
Egen, Inc. |
Biodegradable cross-linked cationic multi-block copolymers for gene delivery and methods of making thereof
|
|
US20080261905A1
(en)
|
2004-11-08 |
2008-10-23 |
K.U. Leuven Research And Development |
Modified Nucleosides for Rna Interference
|
|
US7964571B2
(en)
|
2004-12-09 |
2011-06-21 |
Egen, Inc. |
Combination of immuno gene therapy and chemotherapy for treatment of cancer and hyperproliferative diseases
|
|
ES2407979T3
(es)
|
2004-12-10 |
2013-06-17 |
Kala Pharmaceuticals, Inc. |
Copolímeros de bloques de poli(éter-anhídrido) funcionalizados
|
|
US8187570B1
(en)
|
2005-01-04 |
2012-05-29 |
Gp Medical, Inc. |
Nanoparticles for protein drug delivery
|
|
US8192718B1
(en)
|
2005-01-04 |
2012-06-05 |
Gp Medical, Inc. |
Pharmaceutical composition of nanoparticles
|
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
AU2006336384B2
(en)
|
2005-02-14 |
2010-12-16 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
US8415325B2
(en)
|
2005-03-31 |
2013-04-09 |
University Of Delaware |
Cell-mediated delivery and targeted erosion of noncovalently crosslinked hydrogels
|
|
WO2006107903A2
(en)
|
2005-04-01 |
2006-10-12 |
Intezyne Technologies, Incorporated |
Polymeric micelles for drug delivery
|
|
EP1885403B1
(en)
|
2005-04-12 |
2013-05-08 |
Nektar Therapeutics |
Poly(ethyleneglycol) conjugates of Lysostaphin
|
|
US8246995B2
(en)
|
2005-05-10 |
2012-08-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
|
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
|
US7550264B2
(en)
|
2005-06-10 |
2009-06-23 |
Datascope Investment Corporation |
Methods and kits for sense RNA synthesis
|
|
HUE025208T2
(en)
|
2005-06-16 |
2016-03-29 |
Nektar Therapeutics |
Conjugates with degradable binding and polymer reagents useful in the preparation of such conjugates
|
|
CA2611985C
(en)
|
2005-06-17 |
2016-08-16 |
The University Of North Carolina At Chapel Hill |
Nanoparticle fabrication methods, systems, and materials
|
|
CN101495504A
(zh)
|
2005-06-30 |
2009-07-29 |
阿切埃米克斯有限公司 |
用于生产全2’-修饰的核酸转录产物的材料和方法
|
|
US8101385B2
(en)
|
2005-06-30 |
2012-01-24 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
HUE029465T2
(en)
|
2005-08-10 |
2017-02-28 |
Macrogenics Inc |
Identification and preparation of antibodies with variant fc regions and methods for their use
|
|
US9012219B2
(en)
|
2005-08-23 |
2015-04-21 |
The Trustees Of The University Of Pennsylvania |
RNA preparations comprising purified modified RNA for reprogramming cells
|
|
PL2578685T3
(pl)
|
2005-08-23 |
2020-01-31 |
The Trustees Of The University Of Pennsylvania |
Rna zawierający zmodyfikowane nukleozydy i sposoby jego zastosowania
|
|
BRPI0615420A2
(pt)
|
2005-09-01 |
2011-05-17 |
Novartis Vaccines & Diagnostic |
vacinação múltipla que inclui meningococo do sorogrupo c
|
|
US8420605B2
(en)
|
2005-09-07 |
2013-04-16 |
The University Of Strathclyde |
Hydrogel compositions
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
AU2006314757A1
(en)
|
2005-11-18 |
2007-05-24 |
Bioline Limited |
A method for enhancing enzymatic DNA polymerase reactions
|
|
US8603457B2
(en)
|
2005-12-02 |
2013-12-10 |
University Of Rochester |
Nonsense suppression and genetic codon alteration by targeted modification
|
|
JP2009519033A
(ja)
|
2005-12-16 |
2009-05-14 |
ディアト |
核酸を細胞に送達するための細胞貫通ペプチド結合体
|
|
US8143042B2
(en)
|
2006-01-12 |
2012-03-27 |
Massachusetts Institute Of Technology |
Biodegradable elastomers
|
|
US7951784B2
(en)
*
|
2006-01-26 |
2011-05-31 |
University Of Massachusetts |
RNA interference agents for therapeutic use
|
|
EP1984381B1
(en)
|
2006-01-27 |
2010-09-29 |
Isis Pharmaceuticals, Inc. |
6-modified bicyclic nucleic acid analogs
|
|
WO2007097561A1
(en)
|
2006-02-20 |
2007-08-30 |
Ewha University - Industry Collaboration Foundation |
Peptide having cell membrane penetrating activity
|
|
JP5312050B2
(ja)
|
2006-02-21 |
2013-10-09 |
ネクター セラピューティクス |
分割型の分解性重合体とそれから生成される複合体
|
|
CA2648291A1
(en)
|
2006-04-04 |
2007-11-01 |
Stc.Unm |
Swellable particles for drug delivery
|
|
EP2019691B1
(en)
|
2006-05-15 |
2020-08-12 |
Massachusetts Institute of Technology |
Polymers for functional particles
|
|
US8501478B2
(en)
|
2006-06-15 |
2013-08-06 |
University Of Cincinnati |
Trehalose click polymers for delivery of biologically active molecules
|
|
JP5271902B2
(ja)
|
2006-07-12 |
2013-08-21 |
ノバルティス アーゲー |
コンタクトレンズ製造用の化学線架橋性コポリマー
|
|
JP2010502713A
(ja)
|
2006-09-08 |
2010-01-28 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
粘液を通る輸送を増強するための組成物および方法
|
|
GB0619182D0
(en)
|
2006-09-29 |
2006-11-08 |
Leuven K U Res & Dev |
Oligonucleotide arrays
|
|
US8313777B2
(en)
|
2006-10-05 |
2012-11-20 |
The Johns Hopkins University |
Water-dispersible oral, parenteral, and topical formulations for poorly water soluble drugs using smart polymeric nanoparticles
|
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
|
US8414927B2
(en)
|
2006-11-03 |
2013-04-09 |
Boston Scientific Scimed, Inc. |
Cross-linked polymer particles
|
|
US7999087B2
(en)
|
2006-11-15 |
2011-08-16 |
Agilent Technologies, Inc. |
2′-silyl containing thiocarbonate protecting groups for RNA synthesis
|
|
US8242258B2
(en)
|
2006-12-03 |
2012-08-14 |
Agilent Technologies, Inc. |
Protecting groups for RNA synthesis
|
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
|
JP2010511713A
(ja)
|
2006-12-05 |
2010-04-15 |
ランデック コーポレイション |
薬物送達
|
|
CN101611145B
(zh)
|
2006-12-21 |
2013-08-14 |
诺维信股份有限公司 |
用于在细菌细胞中表达基因的修饰型信使rna稳定化序列
|
|
ES2447516T3
(es)
|
2006-12-21 |
2014-03-12 |
Stryker Corporation |
Formulaciones de liberación sostenida que comprenden cristales BMP-7
|
|
CA2673029C
(en)
|
2006-12-22 |
2017-03-28 |
Archemix Corp. |
Materials and methods for the generation of transcripts comprising modified nucleotides
|
|
JP5606738B2
(ja)
|
2006-12-27 |
2014-10-15 |
ウェルズ ファーゴ バンク ナショナル アソシエイション |
解離可能な連結を有する第ｉｘ因子部分−ポリマー共役体
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
EP2131848A4
(en)
|
2007-02-16 |
2012-06-27 |
Merck Sharp & Dohme |
COMPOSITIONS AND METHODS FOR REINFORCED ACTIVITY OF BIOLOGICAL ACTIVE MOLECULES
|
|
WO2008109712A2
(en)
|
2007-03-05 |
2008-09-12 |
Washington University |
Nanoparticle delivery systems for membrane-integrating peptides
|
|
DK2308514T3
(da)
|
2007-03-23 |
2013-09-02 |
To Bbb Holding B V |
Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren
|
|
CA2702305C
(en)
|
2007-03-30 |
2015-07-21 |
Bind Biosciences, Inc. |
Cancer cell targeting using nanoparticles
|
|
ATE499967T1
(de)
|
2007-04-27 |
2011-03-15 |
Echo Therapeutics Inc |
Hautpermeationsvorrichtung für analytenmessung oder transdermale arzneiabgabe
|
|
AU2008247488B2
(en)
|
2007-05-04 |
2014-02-27 |
Marina Biotech, Inc. |
Amino acid lipids and uses thereof
|
|
US8202983B2
(en)
|
2007-05-10 |
2012-06-19 |
Agilent Technologies, Inc. |
Thiocarbon-protecting groups for RNA synthesis
|
|
US8880907B2
(en)
|
2007-06-21 |
2014-11-04 |
Schneider Electric It Corporation |
Method and system for determining physical location of equipment
|
|
WO2009006438A2
(en)
|
2007-06-29 |
2009-01-08 |
Epicentre Technologies Corporation |
Copy dna and sense rna
|
|
US9144546B2
(en)
|
2007-08-06 |
2015-09-29 |
Clsn Laboratories, Inc. |
Nucleic acid-lipopolymer compositions
|
|
US20090042825A1
(en)
|
2007-08-06 |
2009-02-12 |
Majed Matar |
Composition, method of preparation & application of concentrated formulations of condensed nucleic acids with a cationic lipopolymer
|
|
WO2009042971A2
(en)
|
2007-09-26 |
2009-04-02 |
Intrexon Corporation |
Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
|
|
US8945625B2
(en)
|
2007-12-10 |
2015-02-03 |
The Trustees Of The University Of Pennsylvania |
Regulated delivery systems for inner ear drug application and uses thereof
|
|
CN103911378A
(zh)
|
2007-12-11 |
2014-07-09 |
斯克利普斯研究所 |
涉及mRNA翻译增强因子的组合物和方法
|
|
EP2072618A1
(en)
|
2007-12-14 |
2009-06-24 |
Johannes Gutenberg-Universität Mainz |
Use of RNA for reprogramming somatic cells
|
|
WO2009108891A2
(en)
|
2008-02-29 |
2009-09-03 |
Egen, Inc. |
Modified poloxamers for gene expression and associated methods
|
|
CN102027043A
(zh)
|
2008-03-14 |
2011-04-20 |
艾根股份有限公司 |
生物可降解的交联支链聚(亚烷基亚胺)
|
|
WO2009127060A1
(en)
|
2008-04-15 |
2009-10-22 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
FR2931824B1
(fr)
|
2008-05-29 |
2014-11-28 |
Centre Nat Rech Scient |
Procede de synthese d'arn par voie chimique.
|
|
PL215513B1
(pl)
|
2008-06-06 |
2013-12-31 |
Univ Warszawski |
Nowe boranofosforanowe analogi dinukleotydów, ich zastosowanie, czasteczka RNA, sposób otrzymywania RNA oraz sposób otrzymywania peptydów lub bialka
|
|
PL2285350T3
(pl)
|
2008-06-16 |
2018-03-30 |
Pfizer Inc. |
Sposoby otrzymywania funkcjonalizowanych kopolimerów dwublokowych stanowiących środki kierujące do stosowania przy wytwarzaniu nanocząstek terapeutycznych
|
|
US8318211B2
(en)
|
2008-06-16 |
2012-11-27 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same
|
|
JP6363320B2
(ja)
|
2008-06-16 |
2018-07-25 |
ファイザー・インク |
薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法
|
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
|
US20100009424A1
(en)
|
2008-07-14 |
2010-01-14 |
Natasha Forde |
Sonoporation systems and methods
|
|
US20110224447A1
(en)
|
2008-08-18 |
2011-09-15 |
Bowman Keith A |
Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids
|
|
WO2010027512A2
(en)
|
2008-09-06 |
2010-03-11 |
Chemgenes Corporation |
Rna synthesis - phosphoramidites for synthetic rna in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic rna at the 3' - end
|
|
WO2010030763A2
(en)
|
2008-09-10 |
2010-03-18 |
Bind Biosciences, Inc. |
High throughput fabrication of nanoparticles
|
|
US20100075072A1
(en)
|
2008-09-25 |
2010-03-25 |
Tsung-Wei Chen |
Decorative structure of tree-shaped bells
|
|
US20120015899A1
(en)
|
2008-10-25 |
2012-01-19 |
Plant Bioscience, Limited |
Modified plant virus particles and uses therefor
|
|
JP6087504B2
(ja)
|
2008-11-07 |
2017-03-01 |
マサチューセッツ インスティテュート オブ テクノロジー |
アミノアルコールリピドイドおよびその使用
|
|
JP2012512175A
(ja)
|
2008-12-15 |
2012-05-31 |
バインド バイオサイエンシズ インコーポレイテッド |
治療薬を徐放するための長時間循環性ナノ粒子
|
|
WO2010080724A1
(en)
|
2009-01-12 |
2010-07-15 |
Merck Sharp & Dohme Corp. |
Novel lipid nanoparticles and novel components for delivery of nucleic acids
|
|
WO2010087791A1
(en)
|
2009-01-27 |
2010-08-05 |
Utc Power Corporation |
Distributively cooled, integrated water-gas shift reactor and vaporizer
|
|
US8669085B2
(en)
|
2009-02-05 |
2014-03-11 |
Ut-Battelle, Llc |
Transformation of gram positive bacteria by sonoporation
|
|
CN102348569B
(zh)
|
2009-03-12 |
2015-08-19 |
伊利诺斯工具制品有限公司 |
误加燃料禁止装置
|
|
AU2010226434A1
(en)
|
2009-03-20 |
2011-10-13 |
Egen, Inc. |
Polyamine derivatives
|
|
CN104722342B
(zh)
|
2009-03-24 |
2017-01-11 |
芝加哥大学 |
滑动式芯片装置和方法
|
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
|
EP3427755B1
(en)
|
2009-04-13 |
2020-10-21 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Hpv particles and uses thereof
|
|
MX2011011134A
(es)
|
2009-04-21 |
2012-01-31 |
Selecta Biosciences Inc |
Agentes inmunonanoterapeuticos que proporcionan una respuesta sesgada hacia th1.
|
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
|
CA2760776C
(en)
|
2009-05-05 |
2019-07-09 |
Alnylam Pharmaceuticals, Inc. |
Lipid compositions for the delivery of therapeutic agents
|
|
DE202009007116U1
(de)
|
2009-05-18 |
2010-10-14 |
Amoena Medizin-Orthopädie-Technik GmbH |
Antidekubituskissen
|
|
KR101916875B1
(ko)
|
2009-05-27 |
2018-11-08 |
셀렉타 바이오사이언시즈, 인크. |
면역조절제-중합체성 화합물
|
|
DK3431076T3
(da)
|
2009-06-10 |
2021-12-20 |
Arbutus Biopharma Corp |
Forbedret lipidformulering
|
|
US8569256B2
(en)
|
2009-07-01 |
2013-10-29 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods for the delivery of therapeutic agents
|
|
ES2613498T3
(es)
|
2009-07-01 |
2017-05-24 |
Protiva Biotherapeutics Inc. |
Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos
|
|
RU2012107416A
(ru)
|
2009-07-30 |
2013-09-10 |
ТП Вижн Холдинг Б.В. |
Распределенный перенос изображения
|
|
WO2011012316A2
(de)
|
2009-07-31 |
2011-02-03 |
Ludwig-Maximilians-Universität |
Rna mit einer kombination aus unmodifizierten und modifizierten nucleotiden zur proteinexpression
|
|
CA2769043C
(en)
|
2009-08-01 |
2017-09-12 |
F. Hoffmann-La Roche Ag |
Improved detection of bacterial (mollicutes) contamination
|
|
DK2462147T3
(en)
|
2009-08-05 |
2015-02-23 |
Polyphor Ag |
Conformationally limited fully synthetic macrocyclic compounds
|
|
US9181295B2
(en)
|
2009-08-20 |
2015-11-10 |
Sirna Therapeutics, Inc. |
Cationic lipids with various head groups for oligonucleotide delivery
|
|
US20120253032A1
(en)
|
2009-10-08 |
2012-10-04 |
Merck Sharp & Dohme Corporation |
Novel cationic lipids with short lipid chains for oligonucleotide delivery
|
|
US8859284B2
(en)
|
2009-10-22 |
2014-10-14 |
The United States Of America, As Represented By The Secretary Of The Navy |
Delivery of nanoparticles to neurons
|
|
WO2011140627A1
(en)
|
2009-11-04 |
2011-11-17 |
The University Of British Columbia |
Nucleic acid-containing lipid particles and related methods
|
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
|
WO2011060250A1
(en)
|
2009-11-13 |
2011-05-19 |
Bend Research, Inc. |
Cationic dextran polymer derivatives
|
|
US9415113B2
(en)
|
2009-11-18 |
2016-08-16 |
University Of Washington |
Targeting monomers and polymers having targeting blocks
|
|
GB0920304D0
(en)
|
2009-11-20 |
2010-01-06 |
Medical Res Council |
Novel liposome nanoparticles for tumour magnetic resonance imaging
|
|
SI3338765T1
(sl)
|
2009-12-01 |
2019-05-31 |
Translate Bio, Inc. |
Derivat steroida za dostavo MRNA pri humanih genetskih boleznih
|
|
PT3112467T
(pt)
|
2009-12-07 |
2018-04-16 |
Univ Pennsylvania |
Preparações de arn compreendendo arn modificado purificado para a reprogramação de células
|
|
BR112012016021A8
(pt)
|
2009-12-11 |
2018-06-12 |
Bind Biosciences Inc |
Formulações estáveis para liofilização de partículas terapêuticas
|
|
EP2512487A4
(en)
|
2009-12-15 |
2013-08-07 |
|
THERAPEUTIC POLYMERNANOPARTICLES WITH CORTICOSTEROIDS AND METHOD FOR THE PRODUCTION AND USE THEREOF
|
|
WO2011084521A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticles comprising epothilone and methods of making and using same
|
|
US9295649B2
(en)
|
2009-12-15 |
2016-03-29 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
|
AU2010334911A1
(en)
|
2009-12-23 |
2012-07-12 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
|
JP2011130725A
(ja)
*
|
2009-12-25 |
2011-07-07 |
Contig I:Kk |
Ｌｎａオリゴヌクレオチドとそれを含有する化粧品
|
|
US20110171248A1
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
US9670487B2
(en)
|
2010-01-22 |
2017-06-06 |
Sirna Therapeutics, Inc. |
Cationic lipids for oligonucleotide delivery
|
|
WO2011091307A1
(en)
|
2010-01-23 |
2011-07-28 |
University Of Connecticut |
Affinity hydrogels for controlled protein release
|
|
US20130101609A1
(en)
|
2010-01-24 |
2013-04-25 |
Novartis Ag |
Irradiated biodegradable polymer microparticles
|
|
WO2011106086A1
(en)
|
2010-02-25 |
2011-09-01 |
Albert Einstein College Of Medicine Of Yeshiva University |
Pegylated albumin polymers and uses thereof
|
|
US8889193B2
(en)
|
2010-02-25 |
2014-11-18 |
The Johns Hopkins University |
Sustained delivery of therapeutic agents to an eye compartment
|
|
WO2011112608A1
(en)
|
2010-03-08 |
2011-09-15 |
University Of Rochester |
Synthesis of nanoparticles using reducing gases
|
|
EP2547715A4
(en)
|
2010-03-16 |
2013-10-30 |
Univ Utah Res Found |
SPLICABLE MODIFICATIONS FOR REDUCABLE POLY (AMID ETHYLENIMINE) FOR REINFORCED NUCLEOTIDE DELIVERY
|
|
EP2547345A1
(en)
|
2010-03-18 |
2013-01-23 |
Merck Sharp & Dohme Corp. |
Endosomolytic poly(amidoamine) disulfide polymers for the delivery of oligonucleotides
|
|
US20110230816A1
(en)
|
2010-03-18 |
2011-09-22 |
Tyco Healthcare Group Lp |
Gels for Transdermal Delivery
|
|
US9149432B2
(en)
|
2010-03-19 |
2015-10-06 |
Massachusetts Institute Of Technology |
Lipid vesicle compositions and methods of use
|
|
US8207290B2
(en)
|
2010-03-26 |
2012-06-26 |
Cerulean Pharma Inc. |
Methods and systems for generating nanoparticles
|
|
JP2013528665A
(ja)
|
2010-03-26 |
2013-07-11 |
メルサナ セラピューティックス， インコーポレイテッド |
ポリヌクレオチドの送達のための修飾ポリマー、その製造方法、およびその使用方法
|
|
EP2558074B1
(en)
|
2010-04-08 |
2018-06-06 |
The Trustees of Princeton University |
Preparation of lipid nanoparticles
|
|
CN103002878B
(zh)
|
2010-04-09 |
2015-07-01 |
帕西拉制药有限公司 |
用于配制大直径合成膜囊泡的方法
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
KR101196667B1
(ko)
|
2010-04-15 |
2012-11-02 |
포항공과대학교 산학협력단 |
피에이치 민감성 금속 나노 입자를 이용한 항암제 전달 시스템
|
|
WO2011130624A2
(en)
|
2010-04-16 |
2011-10-20 |
Immune Disease Institute, Inc. |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
WO2011139911A2
(en)
|
2010-04-29 |
2011-11-10 |
Isis Pharmaceuticals, Inc. |
Lipid formulated single stranded rna
|
|
WO2011143230A1
(en)
|
2010-05-10 |
2011-11-17 |
Alnylam Pharmaceuticals |
Methods and compositions for delivery of active agents
|
|
US20130123338A1
(en)
|
2010-05-12 |
2013-05-16 |
Protiva Biotherapeutics, Inc. |
Novel cationic lipids and methods of use thereof
|
|
JP2013531634A
(ja)
|
2010-05-24 |
2013-08-08 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オリゴヌクレオチド送達のための新規なアミノアルコールカチオン性脂質
|
|
CN103118700A
(zh)
|
2010-05-26 |
2013-05-22 |
西莱克塔生物科技公司 |
合成纳米载体联合疫苗
|
|
CN102858375B
(zh)
|
2010-05-26 |
2016-08-10 |
江苏命码生物科技有限公司 |
载有干扰核糖核酸的细胞微粒子、其制备方法及其应用
|
|
WO2011153120A1
(en)
|
2010-06-04 |
2011-12-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
|
WO2011157713A2
(en)
|
2010-06-14 |
2011-12-22 |
F. Hoffmann-La Roche Ag |
Cell-penetrating peptides and uses therof
|
|
BRPI1001959A2
(pt)
|
2010-06-15 |
2012-03-06 |
Instituto De Pesquisas Tecnológicas Do Est. S. Paulo S/a - Ipt |
Nanocarreadores coloidais para ativos hidrofílicos e processo de produção
|
|
WO2011163483A2
(en)
|
2010-06-25 |
2011-12-29 |
Massachusetts Institute Of Technology |
Polymers for biomaterials and therapeutics
|
|
JP5517788B2
(ja)
|
2010-07-01 |
2014-06-11 |
キヤノン株式会社 |
画像形成装置
|
|
KR101130137B1
(ko)
|
2010-07-02 |
2012-03-28 |
연세대학교 산학협력단 |
발광다이오드 모듈
|
|
WO2012006380A2
(en)
|
2010-07-06 |
2012-01-12 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
EP2590626B1
(en)
|
2010-07-06 |
2015-10-28 |
GlaxoSmithKline Biologicals SA |
Liposomes with lipids having an advantageous pka-value for rna delivery
|
|
HRP20161352T1
(hr)
|
2010-07-06 |
2016-12-02 |
Glaxosmithkline Biologicals Sa |
Čestice nalik na virione za unos samoreplicirajućih molekula rna
|
|
US20130177523A1
(en)
|
2010-07-13 |
2013-07-11 |
University Of Utah Research Foundation |
Gold particles and methods of making and using the same in cancer treatment
|
|
WO2012012772A2
(en)
|
2010-07-22 |
2012-01-26 |
The Johns Hopkins University |
Drug eluting hydrogels for catheter delivery
|
|
DE102010032758B4
(de)
|
2010-07-29 |
2012-02-23 |
Fujitsu Technology Solutions Intellectual Property Gmbh |
Computersystem, Verfahren zum Programmieren einer Echtzeituhr und Computerprogrammprodukt
|
|
AU2011285200B2
(en)
|
2010-07-30 |
2014-08-21 |
CureVac SE |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
|
US8524215B2
(en)
|
2010-08-02 |
2013-09-03 |
Janssen Biotech, Inc. |
Absorbable PEG-based hydrogels
|
|
US20130190626A1
(en)
|
2010-08-02 |
2013-07-25 |
Curtin University Of Technology |
Determining location of, and imaging, a subsurface boundary
|
|
AU2011285909B2
(en)
|
2010-08-02 |
2016-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
|
|
WO2012018881A2
(en)
|
2010-08-03 |
2012-02-09 |
Alnylam Pharmaceuticals, Inc. |
Methods and compositions for the regulation of rna
|
|
WO2012021516A2
(en)
|
2010-08-09 |
2012-02-16 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucletide hybrid structures and methods of use thereof
|
|
WO2012024233A2
(en)
|
2010-08-14 |
2012-02-23 |
The Regents Of The University Of California |
Zwitterionic lipids
|
|
US8829329B2
(en)
|
2010-08-18 |
2014-09-09 |
International Business Machines Corporation |
Solar cell and battery 3D integration
|
|
EP2606072A4
(en)
|
2010-08-19 |
2016-04-20 |
Peg Biosciences Inc |
SYNERGISTIC BIOMOLECULAR POLYMER CONJUGATES
|
|
US20120064110A1
(en)
|
2010-08-20 |
2012-03-15 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza a virus hemagglutinin
|
|
US20120225129A1
(en)
|
2010-08-20 |
2012-09-06 |
Cerulean Pharma Inc. |
Conjugates, particles, compositions, and related methods
|
|
PL4066857T3
(pl)
|
2010-08-31 |
2023-03-20 |
Glaxosmithkline Biologicals Sa |
Pegylowane liposomy do dostarczania rna kodującego immunogen
|
|
EP3406730B1
(en)
|
2010-08-31 |
2022-02-23 |
Sirna Therapeutics, Inc. |
Novel single chemical entities and methods for delivery of oligonucleotides
|
|
SMT202300096T1
(it)
|
2010-08-31 |
2023-05-12 |
Glaxosmithkline Biologicals Sa |
Liposomi piccoli per la somministrazione di rna codificante un immunogeno
|
|
CA2809863A1
(en)
|
2010-08-31 |
2012-03-08 |
Novartis Ag |
Lipids suitable for liposomal delivery of protein-coding rna
|
|
US10307372B2
(en)
|
2010-09-10 |
2019-06-04 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
|
US8466122B2
(en)
|
2010-09-17 |
2013-06-18 |
Protiva Biotherapeutics, Inc. |
Trialkyl cationic lipids and methods of use thereof
|
|
EP3943114B1
(en)
|
2010-09-20 |
2024-08-07 |
Sirna Therapeutics, Inc. |
Novel low molecular weight cationic lipids for oligonucleotide delivery
|
|
US20130183718A1
(en)
|
2010-09-21 |
2013-07-18 |
RibpxX GmbH |
Method for Synthesizing RNA using DNA Template
|
|
JP2013540757A
(ja)
|
2010-09-24 |
2013-11-07 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド |
カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル
|
|
EP2618846A1
(en)
|
2010-09-24 |
2013-07-31 |
Mallinckrodt LLC |
Aptamer conjugates for targeting of therapeutic and/or diagnostic nanocarriers
|
|
AU2011307277A1
(en)
|
2010-09-30 |
2013-03-07 |
Merck Sharp & Dohme Corp. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
|
US9782342B2
(en)
|
2010-10-11 |
2017-10-10 |
Wichita State University |
Composite magnetic nanoparticle drug delivery system
|
|
FI122520B
(fi)
|
2010-10-15 |
2012-03-15 |
Vesna Blazevic |
Noroviruksen kapsidi ja rotaviruksen VP6-proteiini käytettäväksi yhdistelmärokotteena
|
|
JP2013545727A
(ja)
|
2010-10-21 |
2013-12-26 |
メルク・シャープ・アンド・ドーム・コーポレーション |
オリゴヌクレオチド送達用の新規低分子量カチオン性脂質
|
|
WO2012054923A2
(en)
|
2010-10-22 |
2012-04-26 |
Bind Biosciences, Inc. |
Therapeutic nanoparticles with high molecular weight copolymers
|
|
DK2635265T3
(en)
|
2010-11-05 |
2018-07-16 |
Sirna Therapeutics Inc |
New low molecular weight cyclic amine-containing cationic lipids for oligonucleotide delivery
|
|
WO2012061703A1
(en)
|
2010-11-05 |
2012-05-10 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
|
WO2012068187A1
(en)
|
2010-11-19 |
2012-05-24 |
Merck Sharp & Dohme Corp. |
Poly(amide) polymers for the delivery of oligonucleotides
|
|
US8901101B2
(en)
|
2010-12-17 |
2014-12-02 |
Sirna Therapeutics, Inc. |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides
|
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
EP2661255B1
(en)
|
2011-01-04 |
2021-03-10 |
Brown University |
Nanotubes as carriers of nucleic acids into cells
|
|
WO2012099755A1
(en)
|
2011-01-11 |
2012-07-26 |
Alnylam Pharmaceuticals, Inc. |
Pegylated lipids and their use for drug delivery
|
|
DE102011002640B4
(de)
|
2011-01-13 |
2021-10-07 |
Evonik Operations Gmbh |
Verfahren zur Aufreinigung von Biphephos
|
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
|
WO2012109121A1
(en)
|
2011-02-07 |
2012-08-16 |
Purdue Research Foundation |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
|
US20120207840A1
(en)
|
2011-02-10 |
2012-08-16 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment Of Non-Melanoma Skin Cancer
|
|
EP2489371A1
(en)
|
2011-02-18 |
2012-08-22 |
Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria |
Carrier peptides for drug delivery
|
|
US8846850B2
(en)
|
2011-02-22 |
2014-09-30 |
Rutgers, The State University Of New Jersey |
Amphiphilic macromolecules for nucleic acid delivery
|
|
US20120237565A1
(en)
|
2011-03-14 |
2012-09-20 |
Intezyne Technologies, Incorporated |
Pegylated polyplexes containing two or more different polymers for polynucleotide delivery
|
|
WO2012125987A2
(en)
|
2011-03-17 |
2012-09-20 |
Massachusetts Institute Of Technology |
Delivery system
|
|
MX366228B
(es)
|
2011-03-25 |
2019-07-03 |
Selecta Biosciences Inc |
Nanoportadores sinteticos de liberacion mediada por osmosis.
|
|
WO2012129648A1
(en)
|
2011-03-25 |
2012-10-04 |
University Of Guelph |
Enhancing protein expression of adeno-associated virus vectors
|
|
US9901554B2
(en)
|
2011-03-31 |
2018-02-27 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
|
EP2691078A1
(en)
|
2011-03-31 |
2014-02-05 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
|
US10647959B2
(en)
|
2011-04-27 |
2020-05-12 |
President And Fellows Of Harvard College |
Cell-friendly inverse opal hydrogels for cell encapsulation, drug and protein delivery, and functional nanoparticle encapsulation
|
|
US20120283503A1
(en)
|
2011-04-29 |
2012-11-08 |
The Johns Hopkins University |
Nanoparticle loaded stem cells and their use in mri guided hyperthermia
|
|
WO2012149268A1
(en)
|
2011-04-29 |
2012-11-01 |
Selecta Biociences, Inc. |
Tolerogenic synthetic nanocarriers for allergy therapy
|
|
EP3409112B1
(en)
|
2011-05-04 |
2022-07-27 |
The University of Nottingham |
Novel polymers which resist bacterial attachment
|
|
US9327029B2
(en)
|
2011-05-05 |
2016-05-03 |
Celacare Technologies, Llc |
Antimicrobial silver hydrogel composition for the treatment of burns and wounds
|
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
|
US20120302940A1
(en)
|
2011-05-26 |
2012-11-29 |
Jackson State University |
Popcorn Shape Gold Nanoparticle For Targeted Diagnosis, Photothermal Treatment and In-Situ Monitoring Therapy Response for Cancer and Multiple Drug Resistance Bacteria
|
|
US20140308363A1
(en)
|
2011-05-31 |
2014-10-16 |
Bind Therapeutics, Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
|
DK2714017T3
(en)
|
2011-06-02 |
2018-09-03 |
Univ California |
MEMBRANE-WRAPPED NANOPARTICLES AND METHOD OF USE
|
|
CA2838063C
(en)
|
2011-06-08 |
2023-07-11 |
Shire Human Genetic Therapies, Inc. |
Cleavable lipids
|
|
WO2012170930A1
(en)
|
2011-06-08 |
2012-12-13 |
Shire Human Genetic Therapies, Inc |
Lipid nanoparticle compositions and methods for mrna delivery
|
|
US20120330084A1
(en)
|
2011-06-27 |
2012-12-27 |
Richard Harris Pantell |
Neutron Source for Neutron Capture Therapy
|
|
FR2977065B1
(fr)
|
2011-06-27 |
2014-07-04 |
Itec E |
Cable pour systeme d'alimentation electrique
|
|
FI123464B
(fi)
|
2011-06-30 |
2013-05-31 |
Ionphase Oy |
Halogeeniton polymeeriseos
|
|
FI125987B
(fi)
|
2011-06-30 |
2016-05-13 |
Convion Oy |
Menetelmä ja järjestely suojakaasujen tarpeen minimoimiseksi
|
|
CN103764121A
(zh)
|
2011-07-06 |
2014-04-30 |
诺华股份有限公司 |
用于递送rna分子的具有有用n:p比的脂质体
|
|
JP5970065B2
(ja)
|
2011-07-08 |
2016-08-17 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ |
ピラゾール酸をアントラニル酸エステルと反応させる工程によってテトラゾール置換アントラニル酸ジアミド誘導体を製造する方法
|
|
US20130012566A1
(en)
|
2011-07-10 |
2013-01-10 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Diagnostic Or Therapeutic Agents For The Treatment of Alopecia
|
|
US9617392B2
(en)
|
2011-07-10 |
2017-04-11 |
President And Fellows Of Harvard College |
Compositions and methods for self-assembly of polymers with complementary macroscopic and microscopic scale units
|
|
WO2013009717A1
(en)
|
2011-07-10 |
2013-01-17 |
Elisabet De Los Pinos |
Virion derived protein nanoparticles for delivering diagnostic or therapeutic agents for the treatment of skin-related diseases
|
|
MX368848B
(es)
|
2011-07-11 |
2019-10-18 |
Tokuyama Corp |
Composición curable fotocrómica.
|
|
WO2013012680A1
(en)
|
2011-07-15 |
2013-01-24 |
3M Innovative Properties Company |
An electrical connector
|
|
KR101339722B1
(ko)
|
2011-07-18 |
2013-12-10 |
이화다이아몬드공업 주식회사 |
Ｃｍｐ 패드 컨디셔너
|
|
ES2670944T3
(es)
|
2011-07-21 |
2018-06-04 |
Croda International Plc |
Copolímeros de bloques de poliéter-poliamida ramificados y métodos de preparación y uso de los mismos
|
|
AU2012290306B2
(en)
|
2011-07-29 |
2017-08-17 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte (CTL) immune responses
|
|
KR20140051357A
(ko)
|
2011-08-26 |
2014-04-30 |
애로우헤드 리서치 코오포레이션 |
Ｉｎ Ｖｉｖｏ 핵산 전달용 폴리(비닐 에스테르) 고분자
|
|
US9126966B2
(en)
|
2011-08-31 |
2015-09-08 |
Protiva Biotherapeutics, Inc. |
Cationic lipids and methods of use thereof
|
|
JP2014531456A
(ja)
|
2011-09-22 |
2014-11-27 |
バインド セラピューティックス インコーポレイテッド |
治療用ナノ粒子と癌を治療する方法
|
|
WO2013072929A2
(en)
|
2011-09-23 |
2013-05-23 |
Indian Institute Of Technology |
Nanop article based cosmetic composition
|
|
JP6250543B2
(ja)
|
2011-09-27 |
2017-12-20 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
ジ脂肪族置換ｐｅｇ化脂質
|
|
EP2763701B1
(en)
|
2011-10-03 |
2018-12-19 |
Moderna Therapeutics, Inc. |
Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
|
|
WO2013055971A1
(en)
|
2011-10-11 |
2013-04-18 |
Arizona Board Of Regents For And On Behalf Of Arizona State University |
Polymers for delivering a substance into a cell
|
|
EP2766407B1
(en)
|
2011-10-12 |
2018-06-27 |
The Curators Of The University Of Missouri |
Pentablock polymers
|
|
CN104023711A
(zh)
|
2011-10-14 |
2014-09-03 |
Stc.Unm公司 |
用于靶向递送(包括负载物的透皮递送)的多孔纳米颗粒支撑的脂质双层(原始细胞)及其方法
|
|
AU2012325997C1
(en)
|
2011-10-18 |
2018-07-05 |
Dicerna Pharmaceuticals, Inc. |
Amine cationic lipids and uses thereof
|
|
WO2013059922A1
(en)
|
2011-10-25 |
2013-05-02 |
The University Of British Columbia |
Limit size lipid nanoparticles and related methods
|
|
KR102272498B1
(ko)
|
2011-10-27 |
2021-07-06 |
메사추세츠 인스티튜트 오브 테크놀로지 |
약물 캡슐화 마이크로스피어를 형성할 수 있는, ｎ-말단 상에 관능화된 아미노산 유도체
|
|
CA2851828A1
(en)
|
2011-10-28 |
2013-05-02 |
Presage Biosciences, Inc. |
Methods for drug delivery
|
|
DK2773326T3
(en)
|
2011-11-04 |
2019-04-15 |
Nitto Denko Corp |
PROCEDURE FOR STERILE PREPARATION OF LIPID NUCLEIC ACID PARTICLES
|
|
US20130116408A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
|
US20130115247A1
(en)
|
2011-11-05 |
2013-05-09 |
Aura Biosciences, Inc. |
Virion Derived Protein Nanoparticles For Delivering Radioisotopes For The Diagnosis And Treatment Of Malignant And Systemic Disease And The Monitoring Of Therapy
|
|
EP4026543B1
(en)
|
2011-11-18 |
2024-08-07 |
Regeneron Pharmaceuticals, Inc. |
Polymer coated protein microparticles for extended release formulations for use in the vitreous of the eye for treating vascular eye disorders
|
|
EP2785326A2
(en)
|
2011-11-29 |
2014-10-08 |
The University of North Carolina at Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
|
US20130142781A1
(en)
|
2011-12-02 |
2013-06-06 |
Invivo Therapeutics Corporation |
Peg based hydrogel for peripheral nerve injury applications and compositions and method of use of synthetic hydrogel sealants
|
|
CA2854054C
(en)
|
2011-12-02 |
2020-05-12 |
Pegasus Laboratories, Inc. |
Amphipathic lipid-based sustained release compositions
|
|
WO2013082529A1
(en)
|
2011-12-02 |
2013-06-06 |
Yale University |
Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
|
|
GB201121070D0
(en)
|
2011-12-07 |
2012-01-18 |
Isis Innovation |
composition for delivery of biotherapeutics
|
|
US20140308304A1
(en)
|
2011-12-07 |
2014-10-16 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
|
JP6305343B2
(ja)
|
2011-12-07 |
2018-04-04 |
アルニラム・ファーマシューティカルズ・インコーポレーテッド |
活性薬剤の送達のための分岐アルキルおよびシクロアルキルを末端とする生分解性脂質
|
|
WO2013086354A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Biodegradable lipids for the delivery of active agents
|
|
EP2787977A4
(en)
|
2011-12-09 |
2015-05-06 |
Univ California |
LIPOSOMAL ACTIVE INVERTING
|
|
US20150000936A1
(en)
|
2011-12-13 |
2015-01-01 |
Schlumberger Technology Corporation |
Energization of an element with a thermally expandable material
|
|
ES2843402T3
(es)
|
2011-12-13 |
2021-07-16 |
Engeneic Molecular Delivery Pty Ltd |
Minicélulas intactas de origen bacteriano para la administración de agentes terapéuticos a tumores cerebrales
|
|
CN104245794A
(zh)
|
2011-12-16 |
2014-12-24 |
麻省理工学院 |
α-氨基脒聚合物及其用途
|
|
RU2649364C2
(ru)
|
2011-12-16 |
2018-04-02 |
Модерна Терапьютикс, Инк. |
Составы на основе модифицированного нуклеозида, нуклеотида и нуклеиновой кислоты
|
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
|
EP2794701B1
(en)
|
2011-12-19 |
2017-03-08 |
The University Of Sydney |
A peptide-hydrogel composite
|
|
RU2014129863A
(ru)
*
|
2011-12-21 |
2016-02-10 |
Модерна Терапьютикс, Инк. |
Способы повышения жизнеспособности или увеличения продолжительности жизни органа или экспланта органа
|
|
WO2013103659A1
(en)
|
2012-01-04 |
2013-07-11 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Stabilizing rna by incorporating chain-terminating nucleosides at the 3'-terminus
|
|
WO2013106086A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
|
WO2013106073A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
|
WO2013106072A1
(en)
|
2012-01-10 |
2013-07-18 |
Sorbent Therapeutics, Inc. |
Compositions comprising crosslinked cation-binding polymers and uses thereof
|
|
CA2861021A1
(en)
|
2012-01-12 |
2013-07-18 |
Stc.Unm |
Immunogenic hpv l2-containing vlps and related compositions and methods
|
|
WO2013106715A1
(en)
|
2012-01-13 |
2013-07-18 |
Allergan, Inc. |
Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
|
|
WO2013105101A1
(en)
|
2012-01-13 |
2013-07-18 |
Department Of Biotechnology |
Solid lipid nanoparticles entrapping hydrophilic/ amphiphilic drug and a process for preparing the same
|
|
CA2863632C
(en)
|
2012-01-19 |
2017-07-11 |
The Johns Hopkins University |
Nanoparticle formulations with enhanced mucosal penetration
|
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
WO2013116126A1
(en)
|
2012-02-01 |
2013-08-08 |
Merck Sharp & Dohme Corp. |
Novel low molecular weight, biodegradable cationic lipids for oligonucleotide delivery
|
|
US20150056158A1
(en)
|
2012-02-03 |
2015-02-26 |
Commonwealth Scientific And Industrial Research Organisation |
Branched polymers
|
|
EP2809345A4
(en)
|
2012-02-03 |
2015-11-25 |
Univ Emory |
IMMUNOSTIMULATING COMPOSITIONS, PARTICLES THEREFOR, AND USES THEREFOR
|
|
WO2013119602A1
(en)
|
2012-02-06 |
2013-08-15 |
President And Fellows Of Harvard College |
Arrdc1-mediated microvesicles (armms) and uses thereof
|
|
KR102081560B1
(ko)
|
2012-02-09 |
2020-02-25 |
라이프 테크놀로지스 코포레이션 |
친수성 중합체성 입자 및 그의 제조 방법
|
|
JP2015513788A
(ja)
|
2012-02-10 |
2015-05-14 |
イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ |
高度ｘジブロックコポリマーの製造、精製及び使用
|
|
BR112014020052B8
(pt)
|
2012-02-16 |
2023-04-18 |
Vlp Therapeutics Llc |
Partícula do tipo vírus, composições, método de produção de anticorpo e uso da referida partícula
|
|
CN104203216A
(zh)
|
2012-02-17 |
2014-12-10 |
效思因公司 |
热敏纳米颗粒制剂及其制备方法
|
|
CA2902256A1
(en)
|
2012-02-17 |
2013-08-22 |
Massachusetts Institute Of Technology |
Self-regulated peptide hydrogel for insulin delivery
|
|
WO2013123492A2
(en)
|
2012-02-17 |
2013-08-22 |
Massachusetts Institute Of Technology |
Glucose-responsive microgels for closed loop insulin delivery
|
|
US10202628B2
(en)
|
2012-02-17 |
2019-02-12 |
President And Fellows Of Harvard College |
Assembly of nucleic acid sequences in emulsions
|
|
ES2669561T3
(es)
|
2012-02-17 |
2018-05-28 |
University Of Georgia Research Foundation, Inc. |
Nanopartículas para el transporte mitocondrial de agentes
|
|
US10398905B2
(en)
|
2012-02-19 |
2019-09-03 |
Nvigen, Inc. |
Uses of porous nanostructure in delivery
|
|
EP2817359B9
(en)
|
2012-02-20 |
2020-03-25 |
Cambridge Enterprise Limited |
Cucurbituril-based hydrogels
|
|
WO2013124867A1
(en)
|
2012-02-21 |
2013-08-29 |
Amrita Vishwa Vidyapeetham University |
Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules
|
|
EP2816964B1
(en)
|
2012-02-21 |
2023-12-27 |
Ben-Gurion University of The Negev Research and Development Authority |
Hydrogel system comprising spatially separated bioactive polypeptides
|
|
GB201203085D0
(en)
|
2012-02-22 |
2012-04-04 |
Univ Manchester |
Hydrogels
|
|
CN108949772A
(zh)
|
2012-04-02 |
2018-12-07 |
现代泰克斯公司 |
用于产生与人类疾病相关的生物制剂和蛋白质的修饰多核苷酸
|
|
EP3520821A1
(en)
|
2012-04-02 |
2019-08-07 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
|
US9512456B2
(en)
|
2012-08-14 |
2016-12-06 |
Modernatx, Inc. |
Enzymes and polymerases for the synthesis of RNA
|