JP2016518838A5 - - Google Patents
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- Publication number
- JP2016518838A5 JP2016518838A5 JP2016511045A JP2016511045A JP2016518838A5 JP 2016518838 A5 JP2016518838 A5 JP 2016518838A5 JP 2016511045 A JP2016511045 A JP 2016511045A JP 2016511045 A JP2016511045 A JP 2016511045A JP 2016518838 A5 JP2016518838 A5 JP 2016518838A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- ndt
- enzyme
- api
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361817064P | 2013-04-29 | 2013-04-29 | |
| US61/817,064 | 2013-04-29 | ||
| PCT/EP2014/058761 WO2014177585A2 (en) | 2013-04-29 | 2014-04-29 | Biocatalytic production of nucleoside analogues as active pharmaceutical ingredients |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016518838A JP2016518838A (ja) | 2016-06-30 |
| JP2016518838A5 true JP2016518838A5 (enExample) | 2017-06-15 |
Family
ID=50771465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016511045A Pending JP2016518838A (ja) | 2013-04-29 | 2014-04-29 | 活性医薬成分としてのヌクレオシドアナログの生体触媒生成 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10184142B2 (enExample) |
| EP (1) | EP2992107B1 (enExample) |
| JP (1) | JP2016518838A (enExample) |
| KR (1) | KR20160030876A (enExample) |
| CA (1) | CA2905306A1 (enExample) |
| WO (1) | WO2014177585A2 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2937420A1 (en) * | 2014-04-23 | 2015-10-28 | Synbias Pharma AG | Method for the synthesis of clofarabine |
| JP2016198075A (ja) * | 2015-04-14 | 2016-12-01 | プラズミア バイオテック，エス．エル． | シトシンヌクレオシドアナログの酵素産生 |
| CN106191172A (zh) * | 2015-05-06 | 2016-12-07 | 普拉斯米亚生物技术有限公司 | 胞嘧啶核苷类似物的酶法制备 |
| EP3115461A1 (en) * | 2015-07-07 | 2017-01-11 | Synbias Pharma AG | Method for the synthesis of pentostatin |
| WO2017024310A1 (en) | 2015-08-06 | 2017-02-09 | Chimerix, Inc. | Pyrrolopyrimidine nucleosides and analogs thereof useful as antiviral agents |
| WO2019060692A1 (en) | 2017-09-21 | 2019-03-28 | Chimerix, Inc. | MORPHIC FORMS OF 4-AMINO-7- (3,4-DIHYDROXY-5- (HYDROXYMETHYL) -ETRAHYDROFURAN-2-YL) -2-METHYL-7H-PYRROLO [2,3-D] PYRIMIDINE-5-CARBOXAMIDE AND THEIR USES |
| CN115109814B (zh) * | 2022-08-26 | 2022-11-29 | 常熟药明康德新药开发有限公司 | 一种制备2’-脱氧-2’-氟-β-D-阿拉伯糖腺苷类似物的方法 |
| CN116064703A (zh) * | 2022-10-21 | 2023-05-05 | 凯莱英生命科学技术(天津)有限公司 | 酶催化合成含有保护基的核苷的方法及组合物 |
| CN115725535B (zh) * | 2022-11-30 | 2023-06-06 | 杭州珲益生物科技有限公司 | 一种n-脱氧核糖转移酶及其在脱氧核苷制备中的应用 |
| CN117660383A (zh) * | 2023-11-14 | 2024-03-08 | 杭州中美华东制药有限公司 | 一种n-脱氧核糖转移酶在催化生产曲氟尿苷中的应用及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
| EP1206551B2 (en) * | 1999-08-20 | 2011-10-26 | Institut Pasteur | Enzymatic synthesis of deoxyribonucleosides |
| US7892838B2 (en) * | 2003-03-28 | 2011-02-22 | Institut Pasteur | Method for the in vivo modification of the synthesis activity of a metabolite by means of the modification of a gene the activity of which is not the original activity |
| US9523084B2 (en) | 2012-11-08 | 2016-12-20 | Centre National De La Recherche Scientifique (Cnrs) | Phosphodeoxyribosyl transferase mutant enzymes and uses thereof |
-
2014
- 2014-04-29 EP EP14725646.5A patent/EP2992107B1/en active Active
- 2014-04-29 WO PCT/EP2014/058761 patent/WO2014177585A2/en not_active Ceased
- 2014-04-29 KR KR1020157030620A patent/KR20160030876A/ko not_active Withdrawn
- 2014-04-29 US US14/787,678 patent/US10184142B2/en not_active Expired - Fee Related
- 2014-04-29 CA CA2905306A patent/CA2905306A1/en not_active Abandoned
- 2014-04-29 JP JP2016511045A patent/JP2016518838A/ja active Pending
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